Ake sifunde ngamaphilisi e-Imatinib? Siza ekulweni kwakho nomdlavuza!

Ingabe wena noma othile omaziyo wake walwa nomdlavuza? Ngezikhathi ezinjalo, odokotela basinikeze imithi ehlukahlukene, akunjalo? I-Imatinib umuthi okhethekile osiza ukulawula amangqamuzana omdlavuza anjalo. Ake sixoxe ngalo muthi ngokuningiliziwe namuhla, akunjalo?

Uhlobo luni lomuthi i-Imatinib?

Kalula nje, i-Imatinib umuthi othuthukisiwe ohlasela amangqamuzana omdlavuza futhi usize ekumiseni ukukhula kwawo. Njenge-sniper, ihlasela amaprotheni athile kumaseli omdlavuza ngenkathi isindisa amangqamuzana anempilo amaningi ngangokunokwenzeka. Lokhu kunciphisa ijubane lamangqamuzana omdlavuza ekuhlukaneni nasekusabalaleni.

Elinye igama lalo muthi emakethe yi -Gleevec . Udokotela wakho angase abize lo muthi ngaleli gama.

Lo muthi usetshenziselwa izifo ezinjani?

Lo muthi, obizwa ngokuthi i-Imatinib, usetshenziswa kakhulu ukwelapha izinhlobo ezithile ze -leukemia , okuyizinhlobo zomdlavuza ezikhula egazini. Ngaphezu kwalokho,:

• I-Myelodysplastic Syndromes yizifo ezihlobene nomnkantsha wamathambo.
• Ngezinye izinhlobo zomdlavuza.
• Iphinde isetshenziswe ezinhlotsheni ezikhethekile zezimila ezakha ohlelweni lwethu lokugaya ukudla (okungukuthi, amathumbu), ezibizwa ngokuthi ama-GIST (Gastrointestinal Stromal Tumors) .

Kodwa khumbula, odokotela ngezinye izikhathi bangawusebenzisa lo muthi kwezinye izimo, ngakho-ke uma unemibuzo mayelana nokuthi kungani unikezwe lo muthi, kungcono njalo ukubuza udokotela wakho noma usokhemisi.

Yiziphi izinto okudingeka uzitshele udokotela ngaphambi kokuthatha umuthi?

Ngaphambi kokuthi uqale ukuthatha i-Imatinib, kunezinto ezimbalwa okufanele uzitshele udokotela wakho. Uma ungabatsheli, bangase bangakulungeli, noma bangase babangele ezinye izinkinga. Ngakho qiniseka ukuthi ubatshela:

• Uma unezinkinga zokopha.
• Uma okwamanje unesifo esithile - ikakhulukazi izifo ezibangelwa amagciwane njenge-chickenpox kanye ne-herpes.
• Uma unesifo senhliziyo noma ukwehluleka kwenhliziyo.
• Uma unesifo sezinso.
• Uma unesifo sesibindi.
• Uma unesifo samaphaphu.
• Uma unezinkinga zesisu.
• Uma uke waba nokusabela kokungezwani komzimba ne-Imatinib esikhathini esidlule, noma kunoma yimuphi omunye umuthi, ukudla, udayi, noma izithasiselo.
• Uma ukhulelwe noma uzama ukukhulelwa.
• Uma ungumama oncelisayo.

Kubaluleke kakhulu ukuze uphephe ukunikeza udokotela lolu lwazi!

Ungayisebenzisa kanjani le mithi ngendlela efanele?

Kubaluleke kakhulu ukwazi kahle ukuthi uwuthatha kanjani lo muthi. Kufanele ulandele ngqo lokho okushiwo udokotela.

• Leli philisi kufanele liphuzwe nengilazi enkulu yamanzi . Ungaliphuzi nenani elincane lamanzi.
• Kungcono ukuyithatha kanye nokudla. Lokhu kungasiza ekunciphiseni ukucasuka kwesisu kanye nesicanucanu.
• Ungawuthathi lo muthi kanye nejusi likagrapefruit nganoma yisiphi isizathu. Ijusi likagrapefruit lingaphazamisa ukusebenza kahle kwalo muthi.
• Phuza umuthi njengoba nje udokotela wakho ekuyalele, ngesikhathi esifanele, ngenani elifanele. Ungalokothi uthathe okungaphezu kwalokho udokotela akutshele kona, noma uwuthathe kaningi.
• Ungayeki ukuthatha lo muthi ngokuzumayo ngaphandle kweseluleko sikadokotela wakho.

Abanye abantu bakuthola kunzima ukugwinya amaphilisi, akunjalo? Uma unenkinga enjalo, khuluma nodokotela wakho, usokhemisi, noma uchwepheshe wezempilo. Bangakusiza ngalokho. Kungase kube nezindlela zokuncibilikisa iphilisi emanzini bese uliphuza, kodwa lokho kufanele kwenziwe kuphela ngaphansi kweseluleko sikadokotela.

Kuthiwani uma lo muthi unikezwa izingane...?

Yebo, kwezinye izimo ezikhethekile, i-Imatinib inganikwa izingane ezincane njengonyaka owodwa ubudala. Kodwa lokho kunqunywa udokotela wezingane. Kunezinto ezimbalwa okufanele uziqaphele kakhulu lapho uzinika izingane. Ngakho-ke, uma unikeza ingane lo muthi, kubalulekile ukukhuluma nodokotela ngawo bese uchaza konke.

Wenzani uma uphuza umuthi omningi ngephutha?

Uma lokho kwenzeka, okungukuthi, uma ucabanga ukuthi uphuze okungaphezu kwalokho obekucabanga, kufanele ushayele ucingo ngokushesha esikhungweni sokulawula ubuthi noma egumbini lezimo eziphuthumayo esibhedlela esiseduze. Ungachithi isikhathi. Lona umuthi owanikezwa wona, ungawabelani nanoma ubani.

Wenzani uma uphuthelwa isikhathi sokubonana nodokotela?

Uma ukhohlwa ngephutha ukuthatha umthamo, thatha ngokushesha nje lapho ukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo wakho olandelayo, yeqa umthamo ophuthelwe bese uthatha umthamo wakho olandelayo ngesikhathi esihleliwe. Ungalokothi uthathe umthamo ophindwe kabili ukuze ubuyisele umthamo okhohliwe. Ukwenza kanjalo kungandisa inani lomuthi owuthathayo.

Yimiphi eminye imithi engasebenzisana nalo muthi?

Lokhu kubaluleke kakhulu . I-Imatinib ingasebenzisana neminye imithi oyithathayo. Lokhu kusho ukuthi uma ithathwa kanye nalowo muthi, imiphumela ye-Imatinib ingashintsha, noma imiphumela yomunye umuthi ingashintsha, noma imiphumela emibi inganda.

Ngakho-ke, uma uthatha i-Imatinib, kufanele utshele udokotela wakho ngayo yonke imithi oyithathayo (eyalelwe udokotela wakho, leyo oyithenga ekhemisi, imithi yendabuko, imikhiqizo yamakhambi, amavithamini). Kufanele futhi utshele udokotela wakho uma ubhema, uphuza utshwala, noma usebenzisa ezinye izidakamizwa.

I-Imatinib ingasebenzisana nemithi elandelayo:

• Eminye imithi yokulwa namagciwane ye -HIV noma i-AIDS
• I-Bosentan
• I-Cisapride
• I-Clarithromycin
• I-Cyclosporine
• I-Dexamethasone
• I-Diltiazem
• Ama-alkaloid e-Ergot (isb., i-dihydroergotamine, i-ergonovine, i-ergotamine, i-methylergonovine)
• I-Erythromycin
• Ijusi le-Grapefruit noma i-grapefruit - Njengoba kushiwo ngaphambili, lokhu kufanele kugwenywe nakanjani.
• Imithi yokwehlisa i-cholesterol (isib. i-atorvastatin, i-lovastatin, i-simvastatin)
• Imithi yokucindezeleka, ukukhathazeka, noma ukugula kwengqondo
• Imithi yokulwa nesikhunta (isb. i-ketoconazole, i-itraconazole)
• Imithi yokushaya kwenhliziyo okungajwayelekile (isib. i-amiodarone, i-bepridil, i-dofetilide, i-encainide, i-flecainide, i-propafenone, i-quinidine)
• Imithi yokwelapha ukuxhuzula (isib. i-carbamazepine, i-phenobarbital, i-phenytoin)
• Amaphilisi okulala
• Ama-NSAID (isb. ibuprofen, naproxen)
• I-Pimozide
• I-Rifabutin
• I-Rifampin
• I-Sildenafil
• I-Sirolimus
• Ikhambi le-St. John's wort
• I-Tacrolimus
• Imigomo
• I-Verapamil
• I-Warfarin - umuthi ovimbela ukujiya kwegazi

Lolu hlu aluphelele. Ngakho-ke , kungcono ukutshela udokotela wakho ngayo yonke imithi oyithathayo. Ikakhulukazi khuluma nodokotela wakho ngaphambi kokuthatha imithi efana ne-paracetamol, i-aspirin, i-ibuprofen, i-ketoprofen, ne-naproxen.

Yiziphi izinto okufanele uziqaphele lapho uthatha umuthi?

Udokotela wakho uzoqapha impilo yakho njalo ngenkathi uthatha i-Imatinib. Lokhu kuzofaka ukuhlolwa kwegazi okuvamile ukuze kubonwe ukuthi umuthi uwuthinta kanjani umzimba wakho nokuthi ngabe kukhona yini imiphumela emibi. Uma uthola izimpawu ezintsha, kufanele utshele udokotela wakho ngokushesha.

Qaphela ukusabela okukhulu kwesikhumba okungenzeka.

Lo muthi ungabangela ukusabela okukhulu kwesikhumba kwabanye abantu. Lokhu kungenzeka emavikini noma ezinyangeni ngemuva kokuqala umuthi. Uma uthola ukuqubuka kwesikhumba okubangelwa umkhuhlane noma ukugula okufana nomkhuhlane, tshela udokotela wakho ngokushesha.Ukuqhuma kungaba bomvu noma nsomi, bese kuba amabala bese kukhishwa. Noma, ukuqhuma okubomvu kungase kuhambisane nama-lymph node avuvukele ebusweni, ezindebeni, entanyeni, noma emakhwapheni.

Zivikele ezifweni

Uma unezimpawu ezifana nomkhuhlane, ukubanda, umphimbo obuhlungu, noma umkhuhlane, ungaziphilisi. Shayela udokotela wakho ngokushesha ukuze uthole iseluleko. Lo muthi unganciphisa amandla omzimba wakho okulwa nezifo. Ngakho zama ukuhlala kude nabantu abagulayo ngangokunokwenzeka.

Ingozi yokopha

Lo muthi ungandisa ingozi yakho yokopha noma ukuklwebheka. Tshela udokotela wakho uma uthola imihuzuko evame ukuklwebheka, ukopha ekhaleni, ukopha ezinsinini lapho uxubha amazinyo akho, noma okunye ukopha okungajwayelekile.

Ukozela kanye nesiyezi

Lomuthi ungakwenza uzizwe ulele noma unesizungu. Ngakho-ke, uze wazi kahle ukuthi lomuthi uthinta kanjani wena, gwema ukushayela, ukusebenzisa imishini, noma ukwenza noma yini edinga ukugxilisa ingqondo.

Lo muthi unjani komama abakhulelwe nabancelisayo?

Lolu udaba olubaluleke kakhulu .

• Ungakhulelwa ngenkathi uthatha lo muthi futhi izinsuku ezingu-14 ngemva kokuyeka umuthi.
• Uma owesifazane ehlela ukukhulelwa, noma ecabanga ukuthi ukhulelwe, kufanele atshele udokotela wakhe. Lo muthi ungabangela imiphumela emibi kakhulu enganeni engakazalwa. Buza udokotela wakho noma usokhemisi ukuze uthole ulwazi olwengeziwe.
• Ungamncelisi umntwana wakho ibele ngenkathi uthatha lo muthi futhi inyanga eyodwa ngemva kokuyeka umuthi.

Yimiphi imiphumela emibi engaba khona yalo muthi?

Njenganoma yimuphi umuthi, i-Imatinib ingabangela imiphumela emibi kwabanye abantu. Akuwona wonke umuntu oyitholayo, kodwa abanye abantu bayayithola. Ezinye zalezi zinto okufanele uzitshele udokotela wakho ngokushesha , kanti ezinye azimbi kakhulu futhi zizophela ezinsukwini ezimbalwa. Kodwa uma ziqhubeka noma zikhathaza, kufanele utshele udokotela wakho .

Imiphumela emibi okufanele uyitshele udokotela wakho ngokushesha:

• Izimpawu zokungezwani komzimba: ukuqubuka kwesikhumba, ukulunywa noma ukuqubuka, ukuvuvukala kobuso, izindebe, ulimi.
• Izinkinga zokuphefumula.
• Izinguquko embonweni.
• Umchamo omnyama.
• Ukuzizwa ugula okuvamile noma izimpawu ezifana nomkhuhlane.
• Izitulo ezinombala okhanyayo.
• Ukulahlekelwa yisifiso sokudla.
• Ukwehla kwenani legazi: Lo muthi ungabangela ukwehla kwenani lamaseli amhlophe egazi, amaseli abomvu egazi, nama-platelet. Lokhu kungandisa ingozi yakho yokuthola izifo nokopha.
• Izilonda zomlomo.
• Ukuqubuka, umkhuhlane, kanye nokuvuvukala kwama-lymph node.
• Ubomvu, ukuqubuka, ukuxebuka noma ukukhululeka kwesikhumba nakho kungavela emlonyeni.
• Ubuhlungu esiswini esingenhla kwesokudla.
• Izimpawu zama-platelet aphansi noma ukopha: ukuklwebheka, amabala abomvu akhomba esikhumbeni, umnyama, indle ephuzile, igazi emchameni, ukuphuma kwegazi ekhaleni.
• Izimpawu zamaseli abomvu aphansi: ubuthakathaka obungavamile, ukukhathala, izikhathi zokuquleka, kanye nokuphelelwa yikhanda.
• Izimpawu zokutheleleka: umkhuhlane noma ukubanda, ukukhwehlela, umphimbo obuhlungu, ubuhlungu noma ubunzima bokuchama.
• Ukuvuvukala kwemilenze noma amaqakala.
• Ubunzima bokuchama noma ukushintsha inani lomchamo.
• Ukuhlanza.
• Ukuphuzi kwamehlo noma isikhumba.

Imiphumela emibi evame ukungadingi ukwelashwa (kodwa kufanele ibikwe kudokotela wakho uma iqhubeka noma ikhathaza):

• Ukuncipha kwesifiso sokudla.
• Uhudo.
• Ukungalali (ubunzima bokulala).
• Ikhanda elibuhlungu.
• Isilungulela.
• Ubuhlungu bamalunga.
• Ukuqaqamba kwemisipha noma ubuhlungu.
• Isicanucanu.
• Isisu esibuhlungu.

Lolu hlu lungase lungahlanganisi yonke imiphumela emibi engaba khona. Uma ubona noma yini engavamile, buza udokotela wakho ngayo. Ungabika futhi imiphumela emibi ku-FDA (Food and Drug Administration) ku-1-800-FDA-1088 (eSri Lanka, ungayibika egunyeni elilawula izidakamizwa elifanele ngodokotela wakho).

Ngingawugcina kanjani lo muthi?

Lomuthi kufanele ugcinwe kude nezingane . Lokho kubaluleke kakhulu.

• Gcina amaphilisi ekamelweni lokushisa, phakathi kwama-degree Celsius angu-15 no-30 (ama-degree Fahrenheit angu-59 no-86).
• Vikela umswakama. Lokho kusho ukuthi ungayigcini ezindaweni ezimanzi njengendlu yokugezela.
• Gcina ibhodlela livaliwe kahle.
• Ungasebenzisi imithi ephelelwe yisikhathi. Yilahle.

Leli pheshana liyisifinyezo kuphela. Lingase lingabi nalo lonke ulwazi. Uma uneminye imibuzo mayelana nalo muthi, khuluma nodokotela wakho, usokhemisi, noma uchwepheshe wezempilo.

Umyalezo Wokuya Ekhaya:

Kulungile, ngakho-ke, kulokho esikhulume ngakho nge-Imatinib, kunezinto ezimbalwa okufanele uzikhumbule nakanjani :

• I-Imatinib umuthi okhethekile osiza ekumiseni ukukhula kwamaseli omdlavuza. Yithathe njengoba nje udokotela wakho ekutshelile, ngesikhathi esifanele, ngenani elifanele.
• Yithathe nokudla namanzi amaningi. Ungalinge uyithathe nejusi yamagilebhisi.
• Tshela udokotela wakho ngayo yonke eminye imithi oyithathayo kanye nazo zonke izimo zakho zezokwelapha . Lokhu kubaluleke kakhulu uma ukhulelwe, uzama ukukhulelwa, noma uncelisa.
• Kuzodingeka ukuthi uhlolwe igazi njalo. Qaphela izinguquko zesikhumba, izimpawu zokutheleleka, kanye nokopha okungavamile. Uma ubona into efana naleyo , tshela udokotela wakho ngokushesha.
• Siphinde sakhuluma ngokuthi yini okufanele uyenze uma uphuza umuthi omningi kakhulu noma uphuthelwe ukudla, akunjalo? Uyakhumbula lezo zinto.
• Gcina lo muthi endaweni epholile, eyomile kude nezingane.

Impi nomdlavuza ayilula. Kodwa ngemithi ethuthukisiwe efana nale, nangokulandela imiyalelo kadokotela ngokucophelela, uzothola amandla amakhulu okunqoba le mpi. Kungakhathaliseki ukuthi unenkinga enjani, ungesabi ukukhuluma nodokotela. Ngikufisela ukululama okusheshayo!

imatinib , i-gleevec, umdlavuza, i-leukemia, i-GIST, izidakamizwa, imiphumela emibi