Ingabe lezi zinguquko emzimbeni wakho zibangelwa yi-histamine? Ake sithole ngokuqinisekile!

Ingabe uzizwa ulunywa ngokuzumayo? Ingabe uthimula ngemva kokuthimula? Noma ingabe uthola ubomvu emzimbeni wakho ngemva kwesikhathi esithile ngemva kokudla ukudla okuthile? Lezi zinto kungenzeka ukuthi zenzeke nakuwe. Esikhathini esiningi, umuntu obangela lokhu kungakhululeki ubizwa ngokuthi i-histamine. Namuhla, ake sixoxe ngokuthi iyini i-histamine, ukuthi kungani ibalulekile emizimbeni yethu, nokuthi kwenzekani uma ikhula.

Iyini ngempela i-histamine?

Kalula nje, i-histamine iyikhemikhali eyenzeka ngokwemvelo emizimbeni yethu. Ifana nesithunywa esincane esisebenza emizimbeni yethu. Igcinwa ngaphakathi kwamaseli athile emizimbeni yethu. Igcinwa kakhulu ezinhlotsheni ezimbili zamaseli abizwa ngokuthi ama-mast cell kanye nama-basophil . Lawa maseli ayingxenye yesimiso sethu somzimba sokuzivikela, uhlelo olusivikela ezifweni. Cabanga ngakho njengenqaba. Lapho isitha (isibonelo, igciwane noma impova) sivela ngaphandle kwale nqaba, onogada abanjengalawa maseli e-mast basebenzisa isikhali esibizwa ngokuthi i-histamine ukuqala impi. Akukhona lokho kuphela, kodwa lo mngane obizwa ngokuthi i-histamine naye uhilelekile ekusizeni isisu sethu ukugaya ukudla kanye neminye imisebenzi yobuchopho.

Kungani le histamine iphuma emizimbeni yethu?

Isizathu esiyinhloko sokukhishwa kwe-histamine emzimbeni ukusabela kokungezwani komzimba . Ake sibone ukuthi kwenzeka kanjani. 1. Ukungezwani komzimba: Ake sithi une-allergy othulini. Uma uya endaweni lapho kunothuli khona, lezo zinhlayiya zothuli (esizibiza ngokuthi ama-allergen ) zingena ekhaleni lakho. Khona-ke amaseli e-mast emzimbeni wethu aqaphela lezi zinhlayiya zothuli "njengesitha". Ayazazi futhi aqale ukuzilwa nazo. Ngalesi sikhathi, i-histamine engaphakathi kwamaseli e-mast ikhishwa ngokuzumayo. Njengebhomu eliqhumayo. Le histamine yiyona ebangela ukuthimula, ikhala elicijile, namehlo alumayo.

• Ezinye zezinto ezivame ukubangela ukungezwani komzimba yilezi:
• Impova
• Izibungu zothuli
• I-dander yezilwane
• Ukudla okuthile (isib. ubisi, amaqanda , amakinati , ukudla kwasolwandle )
• Ukulunywa yizinambuzane
• Eminye imithi

2. Ukulimala noma Ukutheleleka: Uma umzimba ulimele, isikhumba siphukile, noma igciwane lingena, i-histamine iyakhishwa. I-Histamine isiza ukwandisa ukugeleza kwegazi endaweni yokulimala, iletha izinto ezidingekayo namaseli alwa namagciwane ukusiza ukuphulukisa inxeba.

Yini eyenziwa yi-histamine emzimbeni?

Uma i-histamine ikhishwa emzimbeni, iya ezingxenyeni ezahlukene zomzimba wethu futhi inemiphumela ehlukile.

• Imithambo yegazi : I-Histamine ibangela ukuba imithambo yegazi emincane emzimbeni wethu ivuleke. Lokhu kubizwa ngokuthi i-vasodilation . Lokhu kubangela ukuthi igazi eliningi ligeleze kuyo. Yingakho ngezinye izikhathi uma une-allergy, isikhumba sakho siba bomvu bese uzizwa ushisa. Futhi, uketshezi luqala ukuvuza ezindongeni zemithambo yegazi. Lokhu kubangela ukuvuvukala (Ukuvuvukala/ Ukuvuvukala ), ikhala eligobhozayo , namehlo anamanzi.
• Uhlelo lokuphefumula : I-Histamine ibangela ukuthi imisipha emaphashini inciphe. Lokhu kubizwa ngokuthi i-bronchoconstriction . Lokhu kubangela ubunzima bokuphefumula kanye nomuzwa wokuqina esifubeni, ikakhulukazi kubantu abane -asthma .
• Isikhumba: I-Histamine ingavuselela iziphetho zemizwa esikhumbeni futhi ibangele ukulunywa/ukuklwebheka. Iphinde ibe nesibopho sokuvela kwamaqhubu abomvu, avuvukele (ama-hives/urticaria) esikhumbeni.
• Uhlelo lokugaya ukudla: Ukufinyela kwemisipha emathunjini kungabangela ukuqaqamba kwesisu, isicanucanu, ukuhlanza, kanye nesifo sohudo. I-Histamine iyasiza futhi ekukhuthazeni ukukhiqizwa kwe-asidi esiswini.
• Isimiso sezinzwa: I-Histamine isebenza futhi njenge -neurotransmitter ebuchosheni. Lokhu kusho ukuthi iyasiza ekuthwaleni imiyalezo phakathi kwamangqamuzana ezinzwa. Lokhu kusiza kakhulu ekusigcineni siphapheme futhi siqaphile. (Yingakho eminye imithi emidala yokungezwani komzimba isenza silale, ngoba inciphisa nomsebenzi we-histamine ebuchosheni.)

Ziyini izimpawu zokwanda kwe-histamine?

Izimpawu zokugcwala ngokweqile kwe-histamine zingahluka kumuntu nomuntu, kuye ngokuthi ingakanani i-histamine ekhishwe kanye nokuthi yisiphi isitho somzimba esithinteke kakhulu.

• Izimpawu zesikhumba:
• Ukubomvu kwesikhumba, ukulunywa
• I-Eczema, ukuqhuma kwesikhumba
• I-Urticaria/Ama-Hives: Amabala esikhumba asheshe avele, abomvu, avuvukele, futhi aluma kakhulu.
• Izimpawu zekhala nomphimbo:
• Ukuthimula
• I-Rhinorrhea noma ukuminyana kwamakhala
• Impumulo elumayo, umphimbo, kanye nolwanga
• Ukukhwehlela
• Ukuvuvukala komphimbo, ukushintsha kwezwi
• Izimpawu ezihlobene namehlo:
• Amehlo abomvu, alumayo
• Izinyembezi zigeleza emehlweni
• Ukuvuvukala kwamehlo
• Izimpawu ezihlobene namaphaphu:
• Ubunzima bokuphefumula, ukushoda kokuphefumula
• Ukuzwa ukuqina esifubeni
• Ukushaya umoya (ukushaya ikhwela) lapho uphefumula
• Uma une-asthma, i-asthma iyanda.
• Izimpawu ezihlobene nesistimu yokugaya ukudla:
• Isicanucanu, ukuhlanza
• Ubuhlungu besisu, ukuqunjelwa
• Uhudo
• Ezinye izici:
• Ikhanda elibuhlungu (ikhanda elibuhlungu)
• Isiyezi
• Umfutho wegazi ophansi (ikakhulukazi ezimweni ezinzima)

Cabanga nje ukuthi umngane wakho uSugath udle i-shrimp. Kungakapheli nesigamu sehora, umzimba wakhe wonke wawusuluma futhi waba nokuqubuka okubomvu. Wayenenkinga yokuphefumula. Lokhu kungenzeka ukuthi umzimba kaSugath wakhipha i-histamine eningi ngokuzumayo ngenxa ye-shrimp.

Isimo esiyingozi kakhulu: i-Anaphylaxis

Lokhu kuyisimo esibi kakhulu nesisongela impilo sokungezwani komzimba ne-histamine. Lokhu kubizwa ngokuthi i-anaphylaxis . Kulokhu, inani elikhulu le-histamine likhishwa emzimbeni wonke ngesikhathi esisodwa. Lokhu kungenzeka ngemizuzu embalwa. Izimpawu eziyinhloko ze-anaphylaxis yilezi:

• Ubunzima obukhulu bokuphefumula (ukuvaleka komgudu womoya ngenxa yokuvuvukala komphimbo nolimi)
• Isiyezi, ukuzizwa uphelelwe amandla
• Ukushaya kwenhliziyo
• Ukwehla okungazelelwe komfutho wegazi
• Ukudideka
• Isikhumba esiluhlaza okwesibhakabhaka noma esimpunga

Uma ubona noma yiziphi zalezi zimpawu, kuyisimo esiphuthumayo sezokwelapha. Kufanele uyiswe esibhedlela ngokushesha. Ukuhlehlisa ukwelashwa kungaba yingozi empilweni. Ukwelashwa kokuqala ezimweni ezinjalo umjovo we-adrenaline (Adrenaline/Epinephrine) .

Ungayilawula kanjani imiphumela ye-histamine?

Ngenhlanhla, sinezindlela zokulawula lokhu kungakhululeki okubangelwa yi-histamine. 1. Ama-Antihistamine: Lolu uhlobo oluyinhloko lomuthi. Le mithi ivimba izindawo lapho i-histamine ibopha khona (okubizwa ngokuthi ama-histamine receptors) . Lokhu kuvimbela i-histamine ekubeni nomthelela wayo.

• Ama-antihistamine esizukulwane sokuqala: Lawa angabangela ukozela okuthile (isb., i-chlorpheniramine, i-diphenhydramine). Ngakho-ke, kufanele kuqashelwe lapho uwathatha ebusuku noma lapho wenza imisebenzi efana nokushayela.
• Ama-antihistamine esizukulwane sesibili: Lawa awakwazi ukulala kakhulu (isib. iLoratadine, iCetirizine, iFexofenadine). Angcono kakhulu ukuwasebenzisa emini.

Udokotela uzonquma ukuthi iyiphi i-antihistamine ekufanele nokuthi udinga ukuyithatha isikhathi esingakanani. 2. Iziqinisi zamaseli e-mast:Le mithi isebenza ngokuvimbela ukukhishwa kwe-histamine kumaseli e-mast. (Isibonelo: i-Cromolyn sodium). Lokhu kuza njenge-spray yamakhala namaconsi amehlo. 3. Ama-Corticosteroids: Le mithi enamandla enciphisa ukuvuvukala. Ngezinye izikhathi, isetshenziswa isikhathi esifushane ukulawula i-asthma ezimweni ezinzima ze-allergy. 4. Ukugwema izinto ezibangela i-allergy: Uma wazi ukuthi yini oyi-allergy kuyo, kungcono ukugwema lezo zinto ngangokunokwenzeka. Isibonelo, uma u-allergy othulini, ungenza izinto ezifana nokugcina indlu yakho ihlanzekile nokugqoka imaski uma uphuma ngaphandle ngesikhathi se-pollen.

Kuyini Ukungabekezelelani Kwe-Histamine?

Lokhu kuhlukile kancane kunokungezwani komzimba. Ukungabekezelelani i-histamine kwenzeka lapho umzimba wethu ungakwazi ukuphula i-histamine kahle ekudleni noma enanini le-histamine ekhiqizwa emzimbeni. Isizathu esiyinhloko salokhu ukwehla kwe-enzyme i-Diamine Oxidase (DAO) . Kulesi simo, izimpawu ezifanayo nezokungezwani komzimba (ukucasuka, ikhanda elibuhlungu, izinkinga zesisu) zingavela. Kodwa-ke, lokhu kwenzeka lapho udla ukudla okune-histamine eningi (isib. ushizi ogugile, ukudla okubilisiwe, iwayini, imifino nezithelo). Uma unokungabaza ngalokhu, kungcono ukubona udokotela bese ukhuluma naye.

Kufanele ubonane nini nodokotela?

Ngokuvamile, kulungile ukuthenga i-antihistamine ekhemisi uma unezimpawu ezincane zokungezwani komzimba. Kodwa-ke, ezimweni ezinjengalezi, kufanele nakanjani ubone udokotela:

• Uma uvame ukuzwa izimpawu zokungezwani komzimba ezinzima.
• Uma izimpawu zingalawulwa ngemithi ejwayelekile.
• Uma uzizwa unzima ukuphefumula noma ukuqina kwesifuba.
• Uma uhlangabezana nanoma yiziphi izimpawu ze-anaphylaxis (lokhu kuyisimo esiphuthumayo!).
• Uma ufuna ukuthola ukuthi yini ngempela ekwenza uzwele (kunezivivinyo zokungezwani komzimba ngalokho).
• Uma kukhona ukusolakala kokungabekezelelani kwe-histamine.

Udokotela angahlola isimo sakho ngokunembile futhi akunikeze ukwelashwa okungcono kakhulu kanye neseluleko osidingayo.

Okokugcina, izinto okufanele uzikhumbule (Umyalezo Wokuya Ekhaya)

Ngakho-ke, yize i-histamine iyikhemikhali ebalulekile emizimbeni yethu, ngezinye izikhathi ingaba yinkinga kancane.

• I-Histamine idlala indima ebalulekile ekungezwani komzimba, futhi iyasiza nasekupholeni kwamanxeba kanye nokusebenza kwesisu.
• Izinto ezifana nokuthimula, isikhumba esilumayo, amaqhubu, kanye nokuminyana kwamakhala kungabangelwa yi-histamine.
• I-Anaphylaxis yisimo esiyingozi kakhulu esibangelwa yi-histamine. Yisimo esiphuthumayo sezokwelapha esidinga ukwelashwa okuphuthumayo.
• Ama-antihistamine yimithi eyinhloko elawula imiphumela ye-histamine.
• Uma unezimpawu zokungezwani komzimba ezivame ukwenzeka noma ezinzima, qiniseka ukuthi ufuna iseluleko sikadokotela.

Akukho okufanele ukhathazeke ngakho. Iningi lalezi zimo ezihlobene ne-histamine lingaphathwa ngempumelelo. Into ebaluleke kakhulu ukunaka umzimba wakho futhi ufune iseluleko esifanele sezokwelapha uma kudingeka. i-histamine, i-allergy, i-allergy reaction, i-antihistamine, i-anaphylaxis, i-urticaria, i-asthma, i-allergic reaction, i-asthma, i-allergy, i-allergy, i-allergy.