Ngezinye izikhathi sizibuza, "Nginomlando womndeni womdlavuza, ngakho-ke ngiyazibuza ukuthi nami nginamathuba amaningi okuwuthola." Eqinisweni, ezinye izinhlobo zomdlavuza zingabangelwa amathonya ezakhi zofuzo adluliselwa ezizukulwaneni ngezizukulwane. Isibonelo, i-Lynch Syndrome yisimo esikhuphula kakhulu ingozi yomdlavuza, kodwa akukhulunywa kakhulu ngaso. Kubaluleke kakhulu ukuqaphela lokhu. Ngakho ake sixoxe ngakho namuhla.
Kalula nje, iyini i-Lynch Syndrome?
I-Lynch syndrome yisimo sofuzo esidluliselwa kusuka kumzali kuya enganeni, noma ufuzo . Umuntu onalesi simo unamathuba amaningi, noma usengozini, yokuthola izinhlobo ezithile zomdlavuza kunezinye.
Ngokukhethekile, umuntu onalesi simo unethuba eliphakeme ngo-40% kuya ku-80% lokuthola umdlavuza we-colonectal eneminyaka engu-70. Kukhona futhi nengozi ephezulu yokuthola umdlavuza wesibeletho, ama-ovari, kanye nesisu. Okukhethekile ngalokhu ukuthi umdlavuza ungakhula ngaphambi kwesikhathi esivamile somdlavuza, mhlawumbe eminyakeni engu-30 noma engu-40.
Esikhathini esidlule, odokotela babeyibiza nangokuthi i-HNPCC (i-Hereditary Non-Polyposis Colorectal Cancer), kodwa manje igama elithi Lynch syndrome selisetshenziswa kakhulu.
Iyini imbangela yalesi simo?
Ukuze siqonde lokhu, ake sicabange ngemizimba yethu okwesikhashana. Imizimba yethu yakhiwe yizigidigidi zamaseli. Lawa maseli ahlala ehlukana futhi enza amaseli amasha. Cabanga ngakho njengokwenza amakhophi ngomshini wokukopisha. Lapho amaseli ehlukana ngale ndlela, ngezinye izikhathi kwenzeka amaphutha amancane. Kodwa ngenhlanhla, i-DNA yomzimba wethu iqukethe 'izakhi zofuzo zokulungisa okungafani' ezikhethekile eziqaphela la maphutha futhi ziwalungise.
Umuntu one-Lynch syndrome unesici noma iphutha kwenye yalezi 'zakhi zofuzo zokuhlola' . Bese kuthi, lapho lawo maseli ehlukana, amanye amaphutha awalungiswa, futhi amangqamuzana anesici ayaqhubeka ehlukana, futhi amanye amangqamuzana amaningi anesici aqala ukwakheka emzimbeni. Ngokuhamba kwesikhathi, la maseli anesici aba umdlavuza.
Uma umama noma ubaba wakho enalesi simo, unethuba elingu-50% lokusizuza njengefa.
Yiziphi izimpawu ezingase zibonise i-Lynch syndrome?
Kunamaphuzu amaningana abalulekile angaphakamisa ukukhathazeka ngalesi simo. Uma okukodwa noma ngaphezulu kwalokhu kusebenza kuwe noma emndenini wakho, kubaluleke kakhulu ukukhuluma nodokotela.
| Isikhathi Sokusola I-Lynch Syndrome | |
|---|---|
| Umlando womdlavuza womuntu siqu | Une-cancer ye-colorectal ngaphambi kokuba uneminyaka engu-50. |
| Umlando womdlavuza womndeni |
|
| Izimila ezingezona ezomdlavuza | Ama-polyp, uhlobo lokukhula okungenawo umdlavuza emathunjini, ayenzeka esemncane. |
Ungasibona kanjani lesi simo?
Uma wena noma othile emndenini wakho enesifo somdlavuza futhi udokotela wakho esola ukuthi kungenzeka ukuthi kungenxa ye-Lynch syndrome, isampula encane yomdlavuza ingahlolwa. Kunezindlela ezimbili eziyinhloko zokwenza lokhu:
- Ukuhlolwa kwe-Immunohistochemistry (IHC): Lokhu kuhlolwa kwezinhlobo zamaprotheni atholakala kumaseli omdlavuza. Uma amaprotheni akhiqizwa 'yizakhi zofuzo zokuhlola' esikhulume ngazo ngaphambilini engekho kulawo maseli, kungaba uphawu lwe-Lynch syndrome.
- Ukuhlolwa kokungazinzi kwe-Microsatellite (MSI): Lokhu kuhlola ngqo amaphutha ku-DNA yamaseli omdlavuza.
Uma lezi zivivinyo ziqinisekisa ukuthi unesifo se-Lynch, noma uma ucabanga ukuthi usengozini ngoba othile emndenini wakho unalesi simo, ungenza ukuhlolwa kofuzo kusampula yegazi ukuze uthole ukuthi ngabe nawe unalesi sici sofuzo.
Ukusekelwa nguMeluleki wezakhi zofuzo
Kuleli qophelo, udokotela wakho angase akuthumele kumeluleki wezakhi zofuzo. Bazokuchazela izinto eziningi ngalokhu.
- Indlela i-Lynch syndrome ezuzwa ngayo emndenini.
- Okushiwo yimiphumela yombiko wakho wokuhlolwa kwezakhi zofuzo.
- Indlela le miphumela ethinta ngayo ingozi yakho yomdlavuza.
- Amathuba okuthi izingane zakho zizozuza leli jini kuwe.
- Izinketho zakho zokuvimbela umdlavuza.
Khumbula, ukuxilongwa ukuthi une-Lynch syndrome akusho ukuthi uzoba nomdlavuza nakanjani . Kusho ukuthi ubungozi bakho buphezulu kakhulu kunezinye.
Uma une-Lynch syndrome, iphathwa kanjani?
Into engcono kakhulu ongayenza uma wazi ukuthi unalesi simo ukuyohlolwa njalo ukuze uhlole umdlavuza. Ngisho noma umdlavuza uvela, kungenzeka kakhulu ukuthi utholakale usesesigabeni sokuqala futhi welapheke ngokuphelele . Isibonelo, umdlavuza wamathumbu ungelapheka kuma-90% ezimo uma utholakale kusenesikhathi.
Udokotela wakho uzonquma ukuthi yiziphi izivivinyo okudingeka uzenze nokuthi uzidinga kangaki. Izivivinyo ezivame ukunconywa yilezi:
- Ama-colonoscopy: Kusukela eminyakeni engu-20-25, ungase ucelwe ukuba wenze lokhu kuhlolwa njalo ngonyaka noma emibili. Lokhu kuhlola ama-polyps noma izimpawu zomdlavuza emathunjini amakhulu.
- Ama-Endoscopy: Kusukela eminyakeni yakho engama-30, lokhu kungenziwa njalo eminyakeni emi-3-5 ukuhlola isisu namathumbu.
- Ukuhlolwa kwabesifazane: Ngemva kweminyaka engama-30, ukuhlolwa okufana nokuhlolwa kwe-pelvic, i-transvaginal ultrasound, noma i-uterine biopsy kunganconywa njalo ngonyaka ukuhlola isibeletho nama-ovari.
Abanye abantu, ikakhulukazi abesifazane abaye baba nezingane, bakhuluma nodokotela wabo ngokuhlinzwa kokuvimbela ukuze banciphise ingozi yokuba nomdlavuza. Lokhu kusho ukususa ikholoni, isibeletho, noma ama-ovari ngokuhlinzwa ngaphambi kokuba umdlavuza ukhule. Lesi yisinqumo somuntu siqu ngokuphelele.
Ukubaluleka kwendlela yokuphila enempilo
Nakuba kuhlolwa njalo, ukuphila ngendlela enempilo nakho kuyasiza ekunciphiseni le ngozi.
- Yidla ukudla okucebile ngemifino, izithelo, ubhontshisi kanye nokolweni ophelele.
- Vivinya umzimba njalo .
- Lawula isisindo sakho.
- Nciphisa ukusetshenziswa kotshwala.
Ezinye izifundo zikhombisile ukuthi ukuthatha i-aspirin ephansi nsuku zonke kunganciphisa le ngozi, kodwa kudingeka ucwaningo olwengeziwe ngalokhu. Ngakho-ke , ungalokothi uqale ukuthatha imithi wedwa ngaphandle kokubonisana nodokotela wakho.
Umlayezo Wokuya Nawe Ekhaya
- I-Lynch syndrome yisimo sofuzo esidluliselwa ezizukulwaneni ngezizukulwane. Sandisa ingozi yomdlavuza ohlukahlukene, okuhlanganisa umdlavuza wamathumbu amakhulu kanye nowesibeletho.
- Uma othile emndenini wakho eke waba nomdlavuza esemncane (ikakhulukazi ikholoni noma isibeletho), lokho kungaba yimbangela yengozi.
- Uma unokungabaza noma ukukhathazeka ngalokhu, qiniseka ukuthi ukhuluma nodokotela wakho. Uzokunikeza isiqondiso esidingekayo.
- Ukutholwa unalesi simo akusho ukuthi umdlavuza uzovela. Kuyithuba lokuthatha izinyathelo zokuzivikela kumdlavuza kusenesikhathi.
- Ukuhlolwa njalo kuyisikhali sakho esinamandla kakhulu. Ngisho noma umdlavuza ungaba khona, ungatholakala kusenesikhathi futhi welashwe ngempumelelo.
💬 Comments (0)
Awekho amazwana athunyelwe okwamanje. Faka amazwana akho lapha okokuqala ngqa.
Engeza amazwana akho