Ingabe ubuso bakho buvuvukala ngokuzumayo? Ingabe ulimi lwakho luyaqhekeka? Ingabe kungaba yiMelkersson-Rosenthal Syndrome (MRS)?

Wake wakubona, noma wakuzwa ukuvuvukala okungazelelwe kolunye uhlangothi lobuso bakho, udebe oluvuvukile, umuzwa wokucasuka kolunye uhlangothi lobuso bakho, noma ukuqhekeka okungajwayelekile olimini lwakho? Lokhu kungase kungabi yinoma yisiphi isenzakalo esivamile. Kungase kube izimpawu zesimo esingavamile esizokhuluma ngaso.

Iyini i-Melkersson-Rosenthal Syndrome?

Kulungile, ake sibheke ukuthi iyini i-Melkersson-Rosenthal Syndrome, noma i-MRS ngamafuphi. Kalula nje, yisimo esingavamile kakhulu sezinzwa. Okusho ukuthi, sithinta kakhulu uhlelo lwezinzwa ebusweni bethu. Izimpawu eziyinhloko zalesi simo ukuvuvukala kobuso, imifantu engavamile olimini (njengemifantu ejulile), kanye nokukhubazeka kobuso, okuwukulahlekelwa ukusebenza kolunye noma zombili izinhlangothi zobuso. Cabanga, ngokuzumayo, ikhona lomlomo liyadonswa phansi futhi awukwazi ukuvala amehlo akho kahle.

Lesi simo se-'MRS' ngezinye izikhathi singaba uphawu lwesimo esizayo, njengesifo sikaCrohn (isimo sokuvuvukala kwamathumbu esingamahlalakhona) noma i-sarcoidosis (isifo esibangela amaqhubu amancane, avuvukele ezingxenyeni ezahlukene zomzimba). Odokotela ngezinye izikhathi babiza lesi simo ngokuthi ``Orofacial Granulomatosis`` . Yisimo esibangela amaqhubu amancane, anamaqhubu abizwa ngokuthi ama-granuloma, ahambisana nokuvuvukala ebusweni nasemlonyeni.

Ubani ongaba nalesi simo 'se-MRS'? Sivame kangakanani?

Manje ungase ucabange ukuthi, "Ubani ongathola lokhu?" Empeleni, lesi simo esibizwa ngokuthi 'i-MRS' singakhula kunoma yimuphi ubudala. Kodwa-ke, sivame kakhulu kubantu abasha, ngokuvamile abaseminyakeni yabo yokuqala yama-20, lapho izimpawu ziqala ukubonakala.

Kodwa uma kukhulunywa ngokuthi kuvame kangakanani, i-MRS iyisimo esingavamile kakhulu . Kuthiwa sithinta iphesenti elincane kakhulu labantu, cishe u-0.08%. Kodwa ososayensi bakholelwa ukuthi ngenxa yokuthi izimpawu zifana nezinye izifo, kungase kube nabantu abaningi abangakahlolwa. Lokhu kusho ukuthi kungase kube nabantu abaningi abahlushwa yilesi simo kunaleli nani. Ngakho-ke uma unezimpawu ezinjengalezi, ungayeki ukucabanga ukuthi, "Lokhu kwenzeka kubantu abambalwa kakhulu, ayikho indlela engizokuthola ngayo." Into ebaluleke kakhulu ukufuna iseluleko sezokwelapha.

Yiziphi izimbangela ze-'MRS'?

Kulungile, manje ake sibone ukuthi yini ebangela lesi simo 'se-MRS'. Uma sikhuluma iqiniso, ososayensi abakakwazi ukuthola imbangela eqondile . Kodwa kunezinto ezimbalwa okucatshangwa ukuthi zinegalelo kulesi simo:

• Isifo sikaCrohn: Njengoba ngishilo ekuqaleni, lesi yisimo sokuvuvukala kwamathumbu okungapheli. Kutholakale ukuthi abantu abanalesi sifo basengozini enkulu yokuthola i-MRS.
• Ifa lofuzo: Lokhu kusho ukuthi lingadluliselwa ezizukulwaneni ngezizukulwane. Uma othile emndenini eke waba nalesi simo, lokho kungaba yimbangela. Kodwa lokhu akukafakazelwa okwamanje.
• Ukusabela kwe-Hypersensitivity: Lokhu kwenzeka lapho amasosha omzimba wethu esabela ngokweqile entweni ethile (esiyibiza ngokuthi 'i-antigen' noma 'i-allergen' - okusho ukuthi kungaba yinto ebangela ukungezwani komzimba). Kufana nokungezwani komzimba, kodwa kuyinkimbinkimbi kancane.
• I-Sarcoidosis: Lesi yisifo esibangela ukwakheka kwamaqhubu amancane (ama-granuloma) ezingxenyeni ezahlukene zomzimba. Lesi sifo kucatshangwa ukuthi sihlobene ne-MRS.
• Ukutheleleka ngegciwane noma ngamagciwane: Kukhona umbono wokuthi lesi simo ngezinye izikhathi singavela ngemva kokutheleleka okubangelwa yigciwane noma ngamagciwane.

Ingabe i-'MRS' iyi-'(Isifo Sokuzivikela Emzimbeni)'?

Manje abanye abantu bangase bazibuze, "Ingabe lesi ``(isifo esizivikela ngokuzenzakalelayo)''?" Okusho ukuthi, ingabe yisimo lapho amasosha omzimba wethu ehlasela khona amangqamuzana ethu aphilile? Empeleni, 'i-MRS' ayibhekwa njenge-``(isifo esizivikela ngokuzenzakalelayo)'.

Lokhu kuhlukaniswa njengesifo sezinzwa . Lokho kusho ukuthi kuyinkinga yobuchopho noma uhlelo lwezinzwa. Kubizwa nangokuthi isifo se-granulomatous . Lokho kusho ukuthi kuyisimo esingapheli, esivuvukile, esinamaqhubu (i-granuloma) esakheka ezicutshini zomzimba. Uyaqonda? Ngakho-ke asiweli ngqo esigabeni "sokuzivikela komzimba."

Ziyini izimpawu ze-'MRS'?

Kulungile, ake sibheke izimpawu zalesi simo se-'MRS', noma isimo se-'(Orofacial Granulomatosis)' engikhulume ngaso ekuqaleni. Kunezimpawu ezintathu eziyinhloko ezibonakala kulokhu. Lezi zibizwa ngokuthi 'izimpawu ezintathu ezivamile' .

1. Ukukhubazeka kobuso: Lesi yisimo lapho kukhona ubuthakathaka noma ukungazweli ohlangothini olulodwa lobuso, ngezinye izikhathi kuzo zombili izinhlangothi. Lokhu kungase kungabi khona ezigabeni zokuqala, kodwa kungase kuvele ezigabeni zakamuva. Njengoba lesi sifo siqhubeka, isikhathi salokhu kukhubazeka singakhula. Cabanga nje, ngokuzumayo ungakwazi ukuhambisa uhlangothi olulodwa lomlomo wakho, unenkinga yokuvala amehlo akho, noma ukukhishwa kwekhona lomlomo wakho lapho uphuza amanzi.

2. Ukuvuvukala kobuso: Abantu abane-MRS bavame ukuzwa ukuvuvukala kobuso (i-Orofacial edema). Ukuvuvukala kwezindebe (i-Cheilitis granulomatosis) kuvame kakhulu. Umlomo ophezulu uvame ukuvuvukala ngaphambi komlomo ongezansi. Izindebe zingase zome, ziqhekeke, zibe buhlungu, futhi zingase zibe nsundu ngokubomvu. Kwabanye abantu, izindebe zingase zibe lukhuni njengedwala. Akuzona izindebe kuphela, kodwa nezihlathi, izinkophe, futhi ngezinye izikhathi ngisho nesikhumba sekhanda singavuvukala. Lokhu kuvuvukala kungaba kubi kakhulu futhi kuhlale isikhathi eside njengoba lesi sifo siphinde sivela.

3. Ulimi olunemifantu:Lokhu kubangela ukwakheka kwemifantu ejulile, efana nemisele phezulu kolimi. Odokotela babiza lokhu ngokuthi "ulimi lwe-Scrotal" noma "uLingua plicata". Lokhu ngokuvamile akubuhlungu, kodwa abanye abantu bangase babe nokuvuvukala, ukulunywa, kanye nomuzwa oshisayo olimini. Kungabangela nokulahlekelwa ukunambitha futhi kuholele ekuthelelekeni ngomlomo.

Into ebalulekile ukuthi akuwona wonke umuntu onazo zonke lezi zimpawu ezintathu. Abanye abantu bangase babe nesici esisodwa noma ezimbili kuphela kulezi ezintathu. Abanye bangase babe nazo zonke ezintathu.

Lezi zimpawu azihlali njalo. Ziyafika zidlule. Okokuqala, zingase zihlale amahora ambalwa kuphela . Kodwa uma zibuya kamuva, zingase zibe zimbi kakhulu futhi zihlale isikhathi eside.

Ezinye izimpawu

Ngaphezu kwalezi zimpawu eziyinhloko, kungase kube nezinye izimpawu eziningana:

• Isiyezi
• Ikhanda elibuhlungu le-migraine
• Ukukhala ezindlebeni (i-tinnitus) noma ukulahlekelwa ukuzwa
• Ngemva kokuba isifo sesibe sibi kakhulu futhi sesipholile, ngezinye izikhathi izibazi zingase zivele ebusweni .
• Ubunzima bokugwinya
• Izinkinga zokubona: Amehlo omile, ukubona okufiphele, kanye nokuvuvukala kwamehlo (uveitis).

I-MRS ihlolwa kanjani?

Manje ungase uzibuze, "Ngingazi kanjani ukuthi lokhu 'kungu-MRS'?" Empeleni, 'u-MRS' kunzima kancane ukuxilonga. Ngoba izimpawu zakhe zingadidaniswa nezinye izimo. Isibonelo, izimpawu zakhe zingafana 'nokusabela kokungezwani komzimba' noma 'ukukhubazeka kukaBell', esinye isimo esibangela ukukhubazeka kobuso.

Udokotela uvame ukuxilonga i-MRS ngokubheka umlando wakho uma unezimpawu ezimbili kwezithathu engizikhulumile ngaphambili. Ngezinye izikhathi, ukuqinisekisa ukuxilongwa nokususa ezinye izimo, kungase kuthathwe ingcezu encane yezicubu emlonyeni wakho ukuze ihlolwe (i-biopsy). Lokhu kuzobheka ukuba khona kwama-granuloma.

Futhi, udokotela angakudlulisela kwabanye ochwepheshe abaningana, njengoba lokhu kungathinta izinhlelo eziningi. Lokhu kufaka phakathi:

• Udokotela Wezifo Zokungezwani Komzimba
• Udokotela Wesikhumba
• Udokotela Wesisu - Bheka izinto ezifana nesifo sikaCrohn.
• Udokotela Wezifo Zomzimba
• Udokotela wamehlo

Ingabe ikhona ikhambi le-'MRS'? Yiziphi izindlela zokwelapha?

Kulungile, umbuzo omkhulu abantu abaningi abanawo njengamanje uthi, "Ingabe ikhona ikhambi eliphelele lalesi simo 'se-MRS'?" Ngokudabukisayo, alikho ikhambi eliqinisekile le-'MRS' okwamanje.

Ngezinye izikhathi izimpawu ziyaphela ngaphandle kokwelashwa, kodwa zingaphinde zibuye.

Ngakho-ke, uyelapha kanjani? Uma izimpawu zibuya futhi zikhathaza, kunezindlela eziningana zokwelapha ezingasiza ekunciphiseni ubuhlungu, ukuvimbela ukutheleleka, nokuthuthukisa ukubukeka. Zihlanganisa:

• Ama-antibiotic: Uma kukhona ukutheleleka ngamagciwane.
• Ama-Antihistamine: Yehlisa izimpawu ezifana nokungezwani komzimba kanye nokuvuvukala.
• Ama-Corticosteroids: Lena imithi enamandla enciphisa ukuvuvukala nokuvuvukala. Inganikezwa njengomjovo ngqo endaweni evuvukele, noma njengamaphilisi.
• Ama-immunosuppressants: Lawa asiza ekunciphiseni ukuvuvukala ngokulawula kancane umsebenzi wesimiso sokuzivikela komzimba.
• I-Methotrexate: Lona futhi umuthi olawula amasosha omzimba futhi unciphise ukuvuvukala.
• Imithi engeyona eye-steroidal elwa nokuvuvukala (ama-NSAID): Yehlisa ubuhlungu nokuvuvukala (isib. i-Ibuprofen, i-Diclofenac).
• Ukuhlinzwa: Ngezinye izikhathi ukuhlinzwa kungenziwa ukuze kuncishiswe ukuvuvukala kwezindebe ezivuvukele kakhulu noma ukuze kuncishiswe ingcindezi ezinzwa zobuso. Kodwa-ke, lokhu akuvamile ukwenziwa.
• Izithibi ze-TNF-alpha: Lezi futhi ziwuhlobo olukhethekile lwemithi esiza ekunqandeni ukuvuvukala. Ngokuvamile zinikezwa uma ezinye izindlela zokwelapha zingasebenzi.

Lezi zindlela zokwelapha zenzelwe ukulawula izimpawu nokunciphisa ukungakhululeki. Udokotela wakho uzonquma ukwelashwa okukulungele.

Ingabe isimo se-'MRS' singavinjelwa?

Ingabe lesi simo se-'MRS' singavinjelwa? Eqinisweni, njengoba ososayensi bengakaqondi ngokugcwele izimbangela zalokhu, ayikakabikho indlela eqinisekisiwe yokukuvimbela. Ngakho-ke, sidinga ukugxila ekuqapheleni izimpawu kusenesikhathi futhi sifune ukwelashwa okufanele.

Uzolulama kanjani u-'NKK'? Ingabe uzolulama?

Ikusasa liphetheni ngomuntu one-MRS? Lokhu kuyahlukahluka kuye ngomuntu nomuntu. Abanye abantu banezimpawu ezincane kakhulu, njengokunye njalo eminyakeni embalwa, futhi ziyanyamalala zodwa. Kwabanye, izimpawu zingase zivele kaningi, njengangezinsuku ezimbalwa, futhi zingase zibe zimbi kakhulu isikhathi ngasinye.

Lesi simo singaba impilo yonke, futhi ukuvuvukala kungaba okuhlala njalo. Kodwa ososayensi abacabangi ukuthi lesi sifo sithinta impilo yonke. Lokho kusho ukuthi ungaphila impilo evamile naso, kodwa kufanele uphile nezimpawu. Ngakho-ke, ukuhlala uqinile engqondweni nakho kubaluleke kakhulu.

Imibuzo okufanele uyibuze udokotela wakho

Uma une-Melkersson-Rosenthal Syndrome, noma usola ukuthi unayo, kuwumqondo omuhle ukubuza udokotela wakho le mibuzo:

• Ungasho kanjani ngokuqiniseka ukuthi lokhu kuyi-Melkersson-Rosenthal Syndrome? Akunakwenzeka yini ukuthi kube okunye?
• Yibaphi abanye ochwepheshe okufanele ngibabone? (isib., udokotela wesikhumba, udokotela wezinzwa, njll.)
• Uma izimpawu ziphinde zibuya, kufanele ngifune nini iseluleko sezokwelapha? Yiziphi izimpawu okufanele ngikhathazeke ngazo kakhulu?
• Ingabe kufanele ngihlolwe isifo sikaCrohn noma i-sarcoidosis?
• Yini okufanele ngiyenze ukuze ngivimbele ukutheleleka, ukuvuvukala okungapheli, kanye nezibazi?
• Ingabe uncoma ukuhlolwa kwezakhi zofuzo? Kungakutshelani?
• Ingabe kukhona amaqembu okusekelana owaziyo asiza abantu abanalezi zimo? Ingabe kungaba khona izinzuzo zokuthi ngiwajoyine?

Ngakho-ke, yiziphi izinto ezibaluleke kakhulu okufanele sizithathe ekhaya kule ndaba?

I-Melkersson-Rosenthal Syndrome (MRS) yisimo esingavamile kakhulu esithinta imizwa yobuso. Uma uzwa ukuvuvukala kobuso okungazelelwe, ukukhubazeka kobuso, noma imifantu engavamile olimini lwakho, kufanele nakanjani ubone udokotela.

Nakuba kungekho ikhambi eliqondile lalokhu, kunezindlela zokwelapha ezisebenzayo zokulawula izimpawu, ukunciphisa ukungakhululeki, nokuvimbela izinkinga. Ngakho ungakhathazeki. Ngokutholakala kusenesikhathi kanye nokwelashwa okufanele, ungaphila kahle nalesi simo. Awuwedwa, futhi odokotela bakho nabathandekayo bakho bangakusiza.

Isifo iMelkersson -Rosenthal, i-MRS, ukuvuvukala kobuso, ukukhubazeka kobuso, ulimi oluqhekekile, i-neuropathy, i-granulomatosis yomlomo wesibeletho