Ukhathazekile ngamaqhubu noma amaqhubu emzimbeni wakho? Lawa kungaba ama-neurofibroma. Ake sixoxe ngawo!

Wake waphawula amaqhubu amancane noma amaqhubu emzimbeni wakho, kungaba ngaphansi noma ngaphezulu kwesikhumba? Noma wake wambona umuntu omaziyo enawo? Kuvamile ukuzizwa wesaba futhi ukhathazekile uma ubona lokhu. Kodwa akuwona wonke amaqhubu ayingozi. Namuhla sizokhuluma ngohlobo olulodwa olunjalo lweqhubu, okuyisimo esibizwa ngokuthi i-neurofibroma. Ungakhathazeki, sizoxoxa ngalokhu ngokuningiliziwe nangokulula.

Kuyini i-Neurofibroma?

Kalula nje, i-neurofibroma iyisimila esingenabungozi esikhula emangqamuzaneni akho ezinzwa. Empeleni ingenye yeqembu lezimo ezingavamile zofuzo ezibizwa ngokuthi i-neurofibromatosis. Abanye abantu abazalwa bene-neurofibromatosis bangase babe nalezi zimila esikhumbeni, ngaphansi kwesikhumba, noma ngaphakathi emzimbeni.

Kodwa nansi into, ama-neurofibroma amaningi awabangeli izinkinga ezinkulu zempilo . Kodwa-ke, ngezinye izikhathi, uma ekhula kancane, angathinta imizwa eminingi futhi abangele izinkinga ezinkulu zempilo. Uma kunjalo, odokotela bazowasusa ngokuhlinzwa.

Ubani othinteka kakhulu yilesi simo?

Eqinisweni, abantu bazalwa benalezi zinhlayiya ze-neurofibroma. Kodwa into emangalisayo ukuthi, lapho lezi zinhlayiya ziqala ukuvela, kungathatha iminyaka. Esikhathini esiningi, zibonakala ngokucacile ngesikhathi sobusha.

Ngokwezibalo, cishe ingane eyodwa kwezingu-3,000 ingaba nesifo esibizwa ngokuthi i-Neurofibromatosis Type 1 (NF1) . Ngokuvamile sitholakala singakafiki eminyakeni eyi-10. Cishe ama-25% ezingane ezine-NF1, noma cishe eyodwa kwezine, zingaba nezimila ezingaba nkulu ngokwanele ukubangela izinkinga ezinkulu zempilo.

I-neurofibroma ithinta kanjani imizimba yethu?

Indlela ama-neurofibromas athinta ngayo umuntu ngamunye iyahlukahluka kakhulu. Kuya ngohlobo lwesimila, ukuthi sikhulu kangakanani, nokuthi sitholakala kuphi emzimbeni.

• Kwabanye abantu, lokhu kubonakala njengamaqhubu amancane noma amabala esikhumba esijiyile.
• Kodwa-ke, kwabanye abantu abane-neurofibroma enkulu, ingathinta izitho zabo zangaphakathi ngisho nomgogodla.

Cabanga ngakho, ngezinye izikhathi kufana nebhola elincane elakha ngaphakathi emzimbeni. Umphumela walo uncike ekutheni likuphi.

Ingabe lezi ziqhubu zingaba umdlavuza?

Lena inkinga abantu abaningi abanayo. Iningi lama-neurofibroma alibi yisifo esibulalayo. Awanangozi.

Kodwa,Kukhona uhlobo olukhethekile olubizwa ngokuthi i-Plexiform neurofibromas. Cishe u-10% walolu hlobo, noma cishe oyedwa kwabayishumi, unamandla okuba nomdlavuza. Ngakho-ke, kubaluleke kakhulu ukuba udokotela akuhlole uma uneqhubu elinjengaleli.

Ziyini izimpawu ze-Neurofibroma?

Izimpawu ze-neurofibroma ziyahlukahluka. Njengoba kushiwo ngaphambili, zincike ohlotsheni, usayizi, kanye nendawo yesimila. Ngokumangalisayo, abanye abantu abane-neurofibroma bangase bangakhombisi zimpawu. Kodwa-ke, ngezinye izikhathi zingadala izimo ezifana nokukhubazeka noma ngisho nokungaboni.

Ake sibheke lezi zinhlobo ze-neurofibromas kanye nezimpawu ezihambisana nazo:

Ama-neurofibromas asendaweni

Lokhu kubizwa nangokuthi i-cutaneous neurofibromas.

• Lokhu kungabonakala njengamaqhubu amancane emzimbeni wonke .
• Lokhu kuvame ukwenzeka kubantu abaneminyaka ephakathi kuka-20 no-40.
• La maqhubu angaluma futhi angase abe buhlungu uma ecindezelwa .

Ama-neurofibromas asakazeka kabanzi

Lena enye engeyohlobo olufanayo lwe-cutaneous neurofibroma.

• Lezi zivame ukubonakala ekhanda nasentanyeni .
• Kubonakala njengendawo ebanzi, ephakanyisiwe ebusweni besikhumba.
• Ungase uzwe umuzwa wokucasuka noma ukuba ndikindiki uma uwuthinta.

I-Plexiform neurofibromas

Lolu hlobo lwe-neurofibroma luvela emaqenjini ezinzwa.

• Lezi zivame kakhulu ezinganeni ezine-Neurofibromatosis Type 1.
• Lezi zimila zingakhula zibe zinkulu ngokuhamba kwesikhathi . Ngezinye izikhathi, zingabonakala njengezigaxa ezinkulu kakhulu esikhumbeni noma ngaphansi kwesikhumba sezingane.
• Lokhu kungacindezela umgogodla noma imizwa engaphandle, okubangela izimpawu ezifana nokukhubazeka , ubuthakathaka, kanye nokungazweli .
• Kwabanye abantwana abane-Plexiform neurofibromas, ingcindezi yalezi zimila emgogodleni ingabangela isimo esibizwa ngokuthi i-scoliosis . Kubalulekile ukuqaphela lokhu, ngoba njengabazali, sidinga ukuzwela kakhulu lapho into efana nale ithinta ingane.

Zibukeka kanjani lezi ziqhubu? (Ukubukeka)

Amathumba e-neurofibroma, akheka esikhumbeni noma ngaphansi kwaso, abukeka ehluke kakhulu kuma-neurofibroma e-plexiform, akheka ngaphakathi emzimbeni.

• Ama-neurofibromas asendaweni / ama-neurofibromas esikhumba:Lezi yizigaxa ezinombala wesikhumba (amaqhubu) . Ngokuvamile zitholakala esiqwini, ekhanda, entanyeni, ezingalweni nasemilenzeni. Zicishe zibe usayizi we-pea . Zithambile uma uzithinta futhi zinokwakheka okuthambile kancane . Uma ucindezela iqhubu elinjengaleli, lizocwila esikhumbeni, futhi uma ususa isandla sakho, sizophinde sivele. Odokotela bakubiza lokhu ngokuthi "uphawu lwembobo yezinkinobho." Kubukeka njengembobo ehembeni lapho kufakwa khona inkinobho.
• Ama-neurofibroma asakazekile: Lawa angabonakala njengendawo ebomvu, ephakanyisiwe esikhumbeni .
• Ama-neurofibroma e-Plexiform: Lawa angabukeka njengezigaxa ezinkulu ezinenyama ezikhishwe emzimbeni. Odokotela bawachaza “njengesikhwama sezimpethu ngaphansi kwesikhumba.” Uma ubona into efana nale, kungcono ukufuna iseluleko sezokwelapha ngokushesha.

Kuyini i-Neurofibromatosis Type 1 (NF1)?

I-Neurofibromatosis Uhlobo 1 (NF1) yisimo esithinta cishe ingane eyodwa kwezingu-3,300 ezisanda kuzalwa. I-Neurofibroma iwuphawu olulodwa nje lwalesi simo (NF1). Kunezinye izimpawu:

• Izindawo ze-café-au-lait: Lezi zindawo zinsundu kancane, zinombala wekhofi, futhi zinkulu. Lezi zindawo zingakhula zibe zinkulu ngokuhamba kwesikhathi.
• Ukukhula okungenangozi engxenyeni enombala yeso (iris): Lokhu kubizwa nangokuthi amaqhubu e-Lisch.
• Izimila ze-optic nerve: Lezi zibizwa ngokuthi ama-glioma e-optic pathway.

Uma usola ukuthi ingane yakho inesinye salezi zimpawu, kubalulekile ukubonana nodokotela wezingane ukuze uthole iseluleko.

Ziyini izimbangela ze-neurofibroma?

I-Neurofibroma iyisibonakaliso sesimo se-neurofibromatosis uhlobo 1 (NF1). Lesi simo sibangelwa ukuguquka noma ushintsho ku-gene ebizwa ngokuthi i-NF1 gene. I-NF1 gene inemiyalelo yokwenza iphrotheni ebizwa ngokuthi i-neurofibromin.

Bheka manje, le phrotheni ebizwa ngokuthi i-Neurofibromin ibaluleke kakhulu. Iyiphrotheni yokuvimbela isimila . Lokho kusho ukuthi, yilokho okuvimbela amaseli ukuthi akhule ngokushesha kakhulu futhi ahlukane ngokungalawuleki. Ikwenza kanjani lokho? Kukhona enye iphrotheni ebizwa ngokuthi i-Ras protein, esiza amaseli ukuthi akhule futhi ahlukane. Leyo phrotheni ye-Ras ilawulwa yi-Neurofibromin.

Ngakho-ke, uma leso sakhi sofuzo `(NF1)` siguquguquka, siyayeka ukuvimba ukukhula kwamangqamuzana. Bese amangqamuzana anda ngokungalawuleki futhi akhe amathumba. Uyaqonda?

Lesi simo `(NF1)` singadluliselwa ezinganeni uma omunye wabazali enalesi shintsho sezakhi zofuzo. Labo bazali kungenzeka ukuthi basizuze kubazali babo. Kodwa-ke, ngokumangazayo, abantu abangu-50% abane-`(NF1)`, okungukuthi, cishe ingxenye, abanawo umlando womndeni walesi sifo. Lokhu kusho ukuthi lesi simo singavela ngisho noma kwenzeka ushintsho olusha lwezakhi zofuzo.

Odokotela bakuthola kanjani lokhu?

Odokotela bavame ukwenza ukuhlolwa ngokomzimba kuqala ukuze bathole i-neurofibroma. Lokhu kusho ukuthi bayakubheka futhi bahlole amaqhubu.

Ngaphezu kwalokho, ukuhlolwa kwezithombe okufana nalokhu kungasetshenziswa:

• I-CT scan (i-Computed Tomography scan) kanye ne-MRI scan (i-MRI - Magnetic Resonance Imaging): Lezi zivivinyo zisetshenziselwa ukuthola izimila ezincane kakhulu. Ziphinde zisize ekutholeni ukuthi isimila sikuphi nokuthi ukuhlinzwa kuzothinta yini izicubu noma izitho ezizungezile.
• I-PET scan (i-Positron Emission Tomography scan): Lokhu kuhlolwa kusiza odokotela ukuthi banqume ukuthi isimila asiyona ingozi noma siyingozi.

Yiziphi izindlela zokwelapha i-neurofibroma?

Odokotela banezindlela eziningana zokwelapha i-neurofibroma:

• Ukuqapha: Uma i-neurofibroma yakho ingenangozi futhi ingabangeli izinkinga ezinkulu, udokotela wakho uzokutshela ukuthi uze uzohlolwa njalo ukuze abone ukuthi kukhona yini ushintsho.
• Ukuhlinzwa kwepulasitiki: Udokotela wakho angase akuncome ukuhlinzwa kwepulasitiki ukuze kususwe amahlumela angenangozi esikhumbeni noma ngaphansi kwaso.
• Ukuhlinzwa: Uma une-neurofibroma ecindezela amathambo noma izitho zomzimba wakho, udokotela wakho angase ancome ukuhlinzwa ukuze kususwe isimila esiningi ngangokunokwenzeka, noma isimila esiningi ngangokunokwenzeka, ngaphandle kokulimaza izitho zomzimba noma izicubu zakho.

Ingabe ikhona imiphumela emibi yokuhlinzwa?

Imiphumela emibi yokuhlinzwa kwe-neurofibroma iyahlukahluka kusukela ekuhlinzweni kuya ekuhlinzweni. Isibonelo, imiphumela emibi yokuhlinzwa ukususa izimila zesikhumba ihlukile kuleyo yokuhlinzwa ukususa izimila zomgogodla. Uma uhlela ukwenza ukuhlinzwa kwe-neurofibroma, kubalulekile ukubuza udokotela wakho ngemiphumela emibi yokuhlinzwa.

Ingabe ikhona indlela yokuvimbela lokhu ukuthi kungenzeki?

I-Neurofibroma iyisifo esibangelwa izakhi zofuzo, ngakho-ke kunzima ukuvimbela ukukhula kwalezi zimila .

Kwenzekani uma ngine-neurofibroma?

Ngokuvamile, abantu abaningi abane-neurofibromas abathinteki yilesi simo . Kodwa-ke, labo abanezimila eziningi noma ezinkulu bangase bakhathazeke ngokubukeka kwabo futhi bazizwe sengathi kuthinta ikhwalithi yempilo yabo. Uma unalesi simo, khuluma nodokotela wakho mayelana nokuhlinzwa ukuze kususwe izimila ezibonakalayo ezikwenza uzizwe ungakhululekile futhi uzizwe ukhathazekile. Ama-neurofibromas awavamile ukubuya ngemva kokuhlinzwa.

Ngingazinakekela kanjani uma ngine-neurofibroma?

Ama-neurofibroma ayizimila ezingenabungozi, futhi awavamile ukubangela izinkinga ezinkulu zempilo . Kodwa-ke, abantu abanezimila eziningi ze-neurofibroma, noma labo abanezimila ezinkulu, ngezinye izikhathi bangase bazizwe bekhathazekile ngokubukeka kwabo. Ezimweni ezinjalo, ukuhlinzwa kungaba yindlela enhle.

Ukutholwa unesimila esingenabungozi kungase kungabi yinto eyesabekayo noma eyesabekayo njengokutholwa unesimila esinomdlavuza. Kodwa-ke, ngisho nesimila esingenabungozi njenge-neurofibroma singaba nomthelela empilweni yakho.

Lokhu kungathinta ukubukeka kwakho. Abanye abantu bahlakulela ama-neurofibroma, angakhula abe makhulu ngokwanele ukuthi athinte izitho nezicubu eziseduze. Uma utholakale une-neurofibroma, buza udokotela wakho mayelana nokuhlinzwa ukuze kususwe ama-neurofibroma akho.

Futhi, khumbula ukuthi i-neurofibroma ingaba uphawu lwesimo esingavamile, esizuzwe njengefa esibizwa ngokuthi i-neurofibromatosis, esingabangela izinkinga ezinkulu zempilo. Ngakho-ke, kubaluleke kakhulu ukubuza udokotela wakho ukuthi iqhubu lakho liwuphawu lwe-neurofibromatosis.

Umlayezo Wokuya Nawe Ekhaya

Kulungile, ngakho-ke nazi ezinye zezinto ezibaluleke kakhulu okudingeka uzikhumbule kulokho esikhulume ngakho:

• I-Neurofibroma uhlobo lwesimila esikhula emangqamuzaneni ezinzwa futhi ngokuvamile asiyona ingozi .
• Lokhu kungaba uphawu lwesifo sofuzo esibizwa ngokuthi i-neurofibromatosis.
• Nakuba ngokuvamile lokhu kungabangeli izinkinga ezinkulu zempilo, ezinye izinhlobo ezinkulu noma ezithambile zingabangela izinkinga .
• Iphesenti elincane lezinhlobo ze-Plexiform lisengozini yokuba nomdlavuza .
• Izimpawu ziyahlukahluka, kusukela ekuqhumeni kwesikhumba, ukungazweli, ubuhlungu, futhi ngezinye izikhathi ngisho nomonakalo omkhulu wezinzwa.
• Ukuxilongwa kwenziwa ngokuhlolwa kwezokwelapha kanye, uma kudingeka, nge-CT, i-MRI, kanye ne-PET scans.
• Ukwelashwa kuwukubhekisisa, noma ukuhlinzwa uma kudingeka.
• LokhuAkunakuvinjelwa ngoba kuyizakhi zofuzo, kodwa izimpawu zingalawulwa.
• Uma unezinsolo mayelana neqhubu elinjengaleli, kungcono ungesabi futhi ufune iseluleko sezokwelapha .

Khumbula, awuwedwa. Ukuqaphela lezi zimo nokuthola usizo lwezokwelapha oludingekayo kungakusiza uhlale uphilile.

i- neurofibroma, i-neurofibromatosis, i-NF1, amaqhubu esikhumba, izimila zemizwa, izindawo ze-café-au-lait, izifo zofuzo