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Isebenza kanjani ngempela le mithi yesifo sikashukela?
Kalula nje, umgomo oyinhloko wayo yonke le mithi ukwehlisa ushukela wegazi lakho, noma "i-glucose egazini," uye ezingeni elinempilo. Lokhu kusiza futhi ukulawula inani lakho le-"A1c". Ukumelana ne-insulin kuyimbangela enkulu yesifo sikashukela sohlobo 2 (kanye nesifo sikashukela sokukhulelwa).Isimo esibizwa ngokuthi `ukumelana ne-insulin`. Cabanga nje, amangqamuzana emzimbeni wakho (imisipha yakho, amafutha, kanye namaseli esibindi) awasabeli kahle ku-hormone `insulin`. I-insulin yinto eyenziwa yi-pancreas yakho. Iguqula ushukela `glucose` ovela ekudleni esikudlayo ube amandla. Lena inqubo ebalulekile ukuze siphile. Ngakho-ke, uma unesifo sokumelana ne-insulin, i-pancreas yakho kufanele ikhiqize i-insulin eningi ukulawula amazinga kashukela egazini lakho. Kodwa-ke, lapho i-pancreas yakho ingakwazi ukwenza i-insulin eyanele, amazinga kashukela egazini lakho ayakhuphuka. Yilokhu esikubiza ngokuthi amazinga kashukela aphezulu egazini `i-hyperglycemia`. Uma lokhu kuqhubeka, kungabangela izinkinga ezahlukene zempilo. Ukumelana ne-insulin kuyinkimbinkimbi kancane. Imithi yesifo sikashukela isebenza ngezindlela ezahlukene zokwehlisa ushukela egazini. Eminye imithi isiza i-pancreas yakho ukuthi yenze i-insulin eningi. Ngaphezu kwemithi, ukuzivocavoca nakho kubalulekile ekunciphiseni ngokwemvelo ukumelana ne-insulin.Yimiphi imithi yomlomo yesifo sikashukela?
Kunezinhlobo eziningana zemithi esiza ukulawula isifo sikashukela, futhi isebenza ngezindlela ezahlukene. Ake sibheke ukuthi iyini:| Isigaba sezidakamizwa | Indlela esebenza ngayo | Izibonelo |
|---|---|---|
| Izithibi ze-Alpha-glucosidase | Ilawula ukuwohloka kwama-carbohydrate noshukela emathunjini. | `I-Acarbose`, `I-Miglitol` |
| Ama-Biguanides | Yehlisa inani le-glucose ekhiqizwa yisibindi, yandisa ukuzwela kwe-insulin. | 'I-Metformin' |
| Ama-sequestrant e-bile acid | Nakuba kunciphisa i-cholesterol, kunciphisa amazinga kashukela egazini. | `I-Colesevelam` |
| Ama-agonist e-Dopamine-2 | Ithonya ubuchopho ekunciphiseni ukumelana ne-insulin. | 'I-Bromocriptine' |
| Ama-DPP-4 inhibitors (ama-Gliptin) | I-hormone ye-GLP-1 igcina ushukela egazini ulawulwa ngokuwugcina usebenza. | I-Alogliptin, i-Linagliptin, i-Saxagliptin, i-Sitagliptin |
| Ama-Meglitinides (ama-Glinides) | Ivuselela i-pancreas futhi ibangele ukuthi ikhiphe i-insulin. | `I-Nateglinide`, `I-Repaglinide` |
| Izithibi ze-SGLT2 | I-glucose eyengeziwe ikhishwa emchameni. | ``Canagliflozin'', ``Dapagliflozin'', ``Empagliflozin'' |
| Ama-Sulfonylurea | Kuvuselela ama-pancreas futhi kubangele ukuthi akhiphe i-insulin eningi. | "I-Glimepiride", "I-Glipizide", "I-Glyburide" |
| Ama-Thiazolidinediones (ama-TZD) | Kwenza izicubu zizwele kakhulu kwi-insulin. | "I-Rosiglitazone", "I-Pioglitazone" |
Iyini imiphumela emibi yemithi yesifo sikashukela?
Njengayo yonke imithi, imithi yesifo sikashukela ingaba nemiphumela emibi. Umuthi ngamunye ungabangela izinkinga ezahlukene. Imiphumela emibi evame kakhulu izinkinga zesisu (uhudo, ukuqunjelwa, ukuqunjelwa). Into ebaluleke kakhulu ukutshela udokotela wakho nganoma yimiphi imiphumela emibi.Ingozi ye-hypoglycemia
Eminye imithi yesifo sikashukela, ikakhulukazi leyo ebizwa ngokuthi 'i-Meglitinides' kanye ne-'Sulfonylureas', ingabangela amazinga kashukela egazini lakho ukuba ehle ngokuzumayo (i-hypoglycemia). Lokhu kwenzeka lapho ushukela egazini lakho wehla ngaphansi kuka-70 mg/dL. Lesi yisimo esibi kakhulu.Izimpawu ze-hypoglycemia: ukuqhaqhazela, ukujuluka, isiyezi, indlala enkulu, ukungaphumuli, kanye nokushaya kwenhliziyo okusheshayo. Uma lezi zimpawu zenzeka, yidla okuthile okunoshukela noma ama-carbohydrate ngokushesha.
Izinto okufanele uzixoxe nodokotela wakho
- Ukukhulelwa : Uma ukhulelwe noma uhlela ukukhulelwa, kubalulekile ukuxoxa ngemithi yakho nodokotela wakho. Imithi eminingi ephuzwayo, ngaphandle kweMetformin , ayinconywa ngesikhathi sokukhulelwa .
- Eminye imithi: Tshela udokotela wakho ngayo yonke eminye imithi, amavithamini , kanye nezithasiselo ozithathayo.
- Imiphumela emibi: Tshela udokotela wakho nganoma yimiphi imiphumela emibi oyitholayo.
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