Isimiso somzimba wakho sokuzivikela siyindlela emangalisayo yokuzivikela. Kodwa ngezinye izikhathi lesi simiso singasebenza ngendlela ehlukile kancane. Ngezinye izikhathi singaba matasa kakhulu futhi silimaze imizimba yethu, noma ngezinye izikhathi sidinga usizo lokulwa nezitha ezifana namaseli omdlavuza. Ezimweni ezinjalo, sikhuluma ngokwelashwa okukhethekile okusiza isimiso sethu sokuzivikela futhi silawule ukusebenza kwaso. Lokho kuyi-photopheresis.
Kalula nje, kuyini i-photopheresis?
I-Photopheresis iwukwelashwa okusebenzisa ukukhanya ukushintsha ukusebenza kwamaseli akho amhlophe egazi, abizwa ngokuthi ama-lymphocyte. Lawa maseli, abizwa ngokuthi ama-lymphocyte, angamasosha ayinhloko esistimu yethu yomzimba. Yiwo abhubhisa izinto ezifana namaseli omdlavuza, amabhaktheriya, namagciwane. Ngakho-ke, uma kunenkinga ngala ma-lymphocyte, ukwelashwa nge-photopheresis kuyasiza kakhulu.
Cabanga ngale ndlela. Bathatha ingxenye yegazi lakho, balifake emshinini, bese behlukanisa kuphela amangqamuzana amhlophe egazi abizwa ngokuthi ama-lymphocyte. Bese, balixuba nomuthi okhethekile bese bewubeka ekukhanyeni kwe-UV, okushintsha indlela lawo maseli asebenza ngayo. Ekugcineni, lawa maseli aphathwe abuyiselwa emzimbeni wakho kanye nalo lonke igazi lakho.
Ngale ndlela, singaqinisa amasosha omzimba ethu, noma siwalawule uma enza ngendlela engafuneki. Ngamanye amazwi, lokhu kwelashwa kunamandla 'okuvula nokuvala' isistimu yomzimba njengoba kudingeka.
Yiziphi izimo ezisetshenziswayo lokhu kwelashwa?
I-Photopheresis uhlobo lokwelashwa nge-immunotherapy. Okusho ukuthi, iyindlela yokwelapha izifo ngokusebenzisa amasosha omzimba ethu. Kunezindlela eziningana eziyinhloko zokusebenzisa kwayo.
| Isimo sezokwelapha | Incazelo elula |
|---|---|
| I-Cutaneous T-cell lymphoma (CTCL) | Lolu uhlobo olungavamile lomdlavuza wegazi oluthinta isikhumba. Ukwelashwa nge-photopheresis kwaqala ukwethulwa njengokwelashwa kwalesi sifo. Lapho ama-lymphocyte aphathwe ebuyiselwa emzimbeni, asiza ekubhubhiseni amangqamuzana omdlavuza. |
| Isifo Sokuxhunyelelwa Uma Siqhathaniswa Nesifo Somuntu Osiphethe (GVHD) | Ngemva kokuthile okufana nokufakelwa umongo wethambo, amaseli okuqala asanda kutholwa angaqala ukuhlasela umzimba wakho njengokungathi 'uyisitha.' Lokhu kwelashwa kungamisa noma kulawule lokho kuhlasela okungafuneki. |
| Ukwenqatshwa kokufakelwa isitho somzimba | Ngemva kokufakelwa isitho esikhulu, njengephaphu, isibindi, noma inhliziyo, amasosha omzimba angase enqabe isitho esisha. Lokhu kwelashwa kusiza ekuvimbeleni lokho. |
Ezinye izimo zezokwelapha
Ngaphezu kwalezi zimo eziyinhloko, odokotela bangase batuse i-photopheresis kwezinye izimo eziningana zezokwelapha.
- Isifo sikaCrohn
- I-Eczema (i-Atopic dermatitis)
- I-Scleroderma
- I-Psoriasis, isifo sesikhumba
- Isifo sikashukela sohlobo 1
Kufanele sizilungiselele kanjani ngaphambi kokwelashwa?
Udokotela wakho uzochaza lokhu kuwe. Ngokuvamile, bazokucela ukuthi unakekele lezi zinto ngaphambi kokwelashwa.
- Phuza amanzi amaningi: Phuza okungenani izingilazi zamanzi ezingu-8 ngosuku izinsuku ezimbili ngaphambi kokwelashwa. Lokhu kuzosiza ukugeleza kwegazi lakho kangcono, okwenza kube lula ukudonsa igazi ngesikhathi sokwelashwa.
- Gwema i-caffeine notshwala: Izinto ezifana netiye, ikhofi, notshwala zingaqeda amanzi emzimbeni, okunciphisa ukuhamba kwegazi.
- Gwema ukudla okunamafutha: Uma udla ukudla okunamafutha amaningi, njengokudla okuthosiwe namaswidi, kungaba nzima kancane ngomshini ohlukanisa amangqamuzana amhlophe egazi egazini ukwenza umsebenzi wawo.
Lokhu kwelashwa kusebenza kanjani?
Lonke lolu hlelo lwenzeka ngenkathi ulele kahle embhedeni. Luyinqubo engenabuhlungu.
1. Ukukhipha igazi: Umhlengikazi noma udokotela uzokhipha igazi emthanjeni ongalweni yakho noma ngepayipi elikhethekile (i-catheter) elifakwe esifubeni sakho. Uma kudingeka, ukhilimu wokuqeda izinhlungu ungafakwa endaweni ukuvimbela ubuhlungu.
2. Ukuhlukaniswa kwamaseli:Igazi olithathayo liya ngqo emshinini okhethekile. Lo mshini uhlukanisa kuphela amangqamuzana amhlophe egazi abizwa ngokuthi ama-lymphocyte kumaseli abomvu egazi kanye nama-platelet egazini lakho.
3. Ukwengeza umuthi: Umuthi wezitshalo ophephile obizwa ngokuthi `8-methoxypsoralen (8-MOP)` ufakwa emangqamuzaneni egazi amhlophe ahlukanisiwe. Lo muthi usebenza kuphela uma ubekwe ekukhanyeni.
4. Ukwelashwa ngokukhanya: Manje, amangqamuzana amhlophe egazi analo muthi atholakala ekukhanyeni kwe-ultraviolet A (ukukhanya kwe-UVA) ngaphakathi komshini. Ngemuva kwalokho, umuthi uqala ukusebenza futhi ushintshe umsebenzi wamangqamuzana amhlophe egazi.
5. Ukufakwa kabusha: Okokugcina, amangqamuzana amhlophe egazi aphathwe ngale ndlela afakwa emzimbeni wakho, kanye nezinye izingxenye zegazi ezihlukanisiwe ngaphambilini.
Lonke lolu hlelo lungathatha cishe amahora angu-3-4.
Yimiphi imiphumela emibi nezinto okufanele siziqaphele?
I-Photopheresis ibhekwa njengokwelashwa okuphephile kakhulu , futhi abantu abaningi ababi nemiphumela emibi.
Nokho, ngezinye izikhathi izinto ezincane zingenzeka.
- Umfutho wegazi lakho ungase wehle kancane ngesikhathi sokwelashwa. Uma lokhu kwenzeka, ungase unikezwe uketshezi olufakwa emthanjeni ukuze ubuyisele esimweni esijwayelekile.
- Ungase uzizwe unesicanucanu, unesiyezi, noma ubanda, njengalapho unikela ngegazi. Uma uzizwa ngale ndlela, tshela umhlengikazi ngokushesha.
- Ungase ube bomvu, isiyezi, noma umkhuhlane emahoreni angu-6-8 ngemva kokwelashwa. Uma umkhuhlane wakho ungaphezu kwama-degree Celsius angu-37.8 (100 degrees Fahrenheit), tshela udokotela wakho. Angase akuncome ukuthi uthathe umuthi ofana ne-paracetamol.
Izinto okudingeka siziqaphele kakhulu ngemva kokwelashwa
Lokhu kubaluleke kakhulu. Ukwelashwa nge-photopheresis kwenza isikhumba sakho namehlo akho azwele kakhulu elangeni.
Gwema ukuchayeka elangeni eliqondile nelingaqondile amahora angama-24 ngemuva kokwelashwa. Ukukhanya kwelanga okungaqondile ukukhanya okuvela efasiteleni noma ekhethinini.
- Uma uphuma ngaphandle, gqoka izingubo ezimboza umzimba wakho wonke. Sebenzisa isivikelo selanga esine-SPF engama-30 noma ngaphezulu.
- Gqoka izibuko zelanga ezivikela emisebeni ye-UVA, kokubili ngaphakathi nangaphandle, amahora angama-24. Izibuko zelanga "ezimboza amehlo" ezimboza womabili amehlo zingcono kakhulu.
Kuthatha isikhathi esingakanani ukubona imiphumela?
Lokhu kuzohluka kuye ngesimo sakho kanye nenani lokwelashwa. Abanye abantu babona ukuthuthuka okukhulu ezimpawini zabo zingakapheli izinyanga ezingu-3-4. Kwezinye izimo (njenge-scleroderma), kungathatha izinyanga ezingu-6-12 ukuthi izimpawu zithuthuke. Ngakho-ke, ukubekezela kubalulekile ngalokhu kwelashwa. Buza udokotela wakho ngesikhathi ongalindela ukubona imiphumela ngokusekelwe esimweni sakho.
Umlayezo Wokuya Nawe Ekhaya
- I-Photopheresis iyindlela yokwelapha ephephile esebenzisa ukukhanya ukwelapha amangqamuzana akho amhlophe egazi nokulawula umsebenzi wesimiso somzimba sokuzivikela.
- Lokhu kusetshenziselwa kakhulu izinto ezifana nomdlavuza we-CTCL, izimo ze-GVHD, kanye nokuvimbela ukwenqatshwa ngemva kokufakelwa izitho zomzimba.
- Ukwelashwa akubuhlungu, kodwa ukuvikelwa elangeni kuyimfuneko emahoreni angama-24 ngemva kokwelashwa.
- Kungathatha isikhathi ukubona imiphumela, ngakho-ke kubalulekile ukubekezela nokufuna ukwelashwa.
- Khuluma nodokotela wakho ngokukhululekile nganoma yiziphi izinkinga, ukwesaba, noma ukungabaza onakho ngalokhu.
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