Mhlawumbe wena noma othile emndenini wakho unikezwe umuthi obizwa ngokuthi 'i-Ruxolitinib' ngudokotela wakho. Igama lingase lizwakale liyinkimbinkimbi kancane. Kodwa ungesabi. Into ebaluleke kakhulu ukuba nolwazi oluphelele ngale mithi ekhethekile bese uyisebenzisa. Ngakho-ke namuhla, ake sixoxe ngokuthi uyini lo muthi, wenzani, nokuthi yini okudingeka siyiqaphele lapho siwusebenzisa.
Kuyini i-Ruxolitinib?
Kalula nje, i-Ruxolitinib umuthi ohlasela amaprotheni athile ngaphakathi kwamaseli omzimba wethu futhi ulawula umsebenzi wawo, okusho ukuthi uvimba amangqamuzana ekukhuleni. Lokhu kubizwa ngokuthi ukwelashwa okuqondiwe .
Lo muthi usetshenziswa kakhulu ukwelapha izimo ezintathu:
- I-Myelofibrosis: Lokhu kwenzeka lapho izicubu ezine-fibrous ziqoqana emnkantsheni wethambo, ziphazamisa ukukhiqizwa kwamangqamuzana egazi anempilo.
- I-Polycythemia Vera: Kulesi simo, umzimba ukhiqiza amangqamuzana egazi abomvu amaningi kunalokho okudingekayo.
- Isifo se-graft-versus-host: Lokhu kwenzeka ngemva kokuthile okufana nokufakelwa umnkantsha, lapho amangqamuzana atshaliwe eqala ukuhlasela imizimba yethu.
Udokotela wakho angase futhi ancome lo muthi kwezinye izimo.
Izinto okudingeka uzitshele udokotela wakho ngaphambi kokuqala imithi
Ngaphambi kokuqala lo muthi, kubaluleke kakhulu ukutshela udokotela wakho nganoma yiziphi izinkinga zempilo onazo. Uma unezinye zalezi ezilandelayo, qiniseka ukuthi uyamtshela ngazo.
| Isimo | Incazelo |
|---|---|
| Izifo zenhliziyo nezinkinga zemithambo yegazi | Uma uke waba nokuhlaselwa yinhliziyo noma isifo sohlangothi ngaphambilini, izinkinga zokujiya kwegazi, noma amazinga aphezulu e-cholesterol. |
| Izifo | Umlando wamanje noma wangaphambilini weSifo Sofuba (TB), i-Hepatitis, noma olunye ukutheleleka ngamagciwane, amagciwane, noma isikhunta. |
| Isifo sezinso noma sesibindi | Uma unesifo sezinso noma usebenzisa i-dialysis, noma unesifo sesibindi. |
| Izinkinga zegazi nomdlavuza | Uma unenani eliphansi legazi, amaseli amhlophe egazi aphansi, amaseli abomvu egazi aphansi, noma ama-platelet aphansi, noma uma unomunye umdlavuza. |
| Amanye amaphuzu | Tshela udokotela wakho uma ubhema, uzama ukukhulelwa, ukukhulelwa, noma uncelisa. Tshela udokotela wakho uma une-allergies ku-ruxolitinib noma kunoma yimuphi omunye umuthi noma ukudla. |
Ngingawusebenzisa kanjani lo muthi?
Lo muthi kufanele uphuzwe ngomlomo nengilazi yamanzi. Ungaphuzwa nokudla noma ngaphandle kokudla. Kodwa-ke, uma uzwa ubuhlungu besisu, kungcono ukuwuphuza nokudla.
Kubaluleke kakhulu: Gwema ukuphuza ijusi likagrapefruit ngokuphelele ngenkathi uthatha lo muthi, ngoba ijusi likagrapefruit lingathinta indlela lo muthi osebenza ngayo.
Zama ukuphuza umuthi wakho ngesikhathi esifanayo nsuku zonke. Thatha umthamo njengoba nje udokotela wakho ekuyalele. Uma unemiphumela emibi, udokotela wakho angakutshela ukuthi ushintshe umthamo noma uyeke ukuthatha umuthi. Ungalokothi ushintshe umthamo noma uyeke ukuthatha umuthi ngaphandle kweseluleko sikadokotela wakho.
Kuthiwani uma uphuthelwa umthamo othile womuthi?
Thatha umthamo ophuthelwe ngokushesha nje lapho ukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo wakho olandelayo, yeqa umthamo ophuthelwe bese uthatha umthamo olandelayo ngesikhathi esihleliwe. Ungathathi umthamo ophindwe kabili nganoma yisiphi isizathu.
Kuthiwani uma ngiphuza umuthi omningi kakhulu?
Uma ucabanga ukuthi uthathe umuthi omningi kakhulu, shayela ngokushesha iNational Poisons Information Centre eColombo National Hospital . Noma uye e-Emergency Treatment Unit (ETU) yesibhedlela esiseduze.
Eminye imithi engasebenzisana ne-Ruxolitinib
Tshela udokotela wakho ngayo yonke imithi oyithathayo, okuhlanganisa imithi kadokotela kanye nemithi ethengiswa ngaphandle kwemithi kadokotela, imithi yendabuko, amavithamini, kanye nemikhiqizo yamakhambi (njenge-St. John's wort). Eminye imithi ingasebenzisana ne-Ruxolitinib.
Ngezansi kunezibonelo ezimbalwa nje:
- Eminye imithi yokulwa namagciwane esetshenziswa i-HIV noma i-AIDS
- Imithi yokutheleleka kwesikhunta (isb. i-fluconazole, i-ketoconazole)
- Amanye ama-antibiotic (isib. i-clarithromycin, i-erythromycin)
- Eminye imithi yokwelapha isithuthwane/ ukuxhuzula (isib. i-carbamazepine, i-phenytoin)
- I-Rifampin (umuthi wesifo sofuba)
- Umkhiqizo wezitshalo i-St. John's wort
Lolu hlu aluphelele, ngakho-ke kubaluleke kakhulu ukutshela udokotela wakho ngakho konke okuthathayo .
Yiziphi izinto ezikhethekile okufanele uziqaphele lapho uthatha umuthi?
Kungumqondo omuhle ukunaka izinguquko emzimbeni wakho ngenkathi uthatha lo muthi.
- Ukuhlolwa kwegazi: Udokotela wakho uvame uku-oda ukuhlolwa kwegazi ukuze ahlole izinto ezifana noshintsho ngobukhulu bamaseli akho egazi.
- Ingozi yokutheleleka: Lo muthi unganciphisa ikhono lomzimba lokulwa nezifo, okungukuthi, ukuzivikela komzimba. Ngakho-ke, uma uhlangabezana nezimpawu ezifana nomkhuhlane, umkhuhlane, umphimbo obuhlungu, ukukhwehlela, ungaziphilisi, kodwa tshela udokotela wakho. Nciphisa ukuya ezindaweni lapho abantu abagulayo betholakala khona ngangokunokwenzeka.
- Ukopha nokuklwebheka: Uma ukhubeka emzimbeni wakho ngendlela engachazeki, noma uma ukopha kungayeki ngisho nokulimala okuncane, yazisa udokotela wakho.
- Ingozi Yomdlavuza: Abanye abantu abasebenzisa lo muthi bangase babe nengozi eyengeziwe yokuba nezinye izinhlobo zomdlavuza, njengomdlavuza wesikhumba. Ngakho-ke mboza isikhumba sakho uma uphuma elangeni, sebenzisa isithako sokuvikela ilanga, bese ukhuluma nodokotela wakho ngalokhu.
- Ukutheleleka kobuchopho okukhulu: Akuvamile ukuthi ezinye iziguli zingenwe ukutheleleka kobuchopho okukhulu. Tshela udokotela wakho ngokushesha uma unenkinga yokubona, yokukhuluma, yokucabanga, yokuhamba, noma yokuma, noma uma udidekile.
- Omama abancelisayo: Ungancelisi ingane yakho ngenkathi uthatha lo muthi futhi amasonto amabili ngemva kokuyeka umuthi.
Yimiphi imiphumela emibi engingayithola?
Njenganoma yimuphi umuthi, i-Ruxolitinib ingabangela imiphumela emibi. Eminye iyingozi, kanti eminye ivamile. Kubalulekile ukuqaphela lokhu.
| Umphumela ongemuhle | Incazelo |
|---|---|
| Imiphumela emibi kakhulu okufanele ibikwe kudokotela wakho ngokushesha | |
| Ukusabela kokungezwani komzimba | Ukuqubuka kwesikhumba, ukulunywa, ukuvuvukala kobuso, izindebe noma ulimi. |
| Ihluli | Ubuhlungu esifubeni, ubunzima bokuphefumula, ubuhlungu, ukuvuvukala, noma umuzwa ofudumele emlenzeni. |
| Isifo senhliziyo | Ubunzima bokuphefumula, ubuhlungu noma ukuqina esifubeni, entanyeni, emhlane, noma ezingalweni, ukukhathala okukhulu. |
| Isifo sohlangothi | Ukushintsha kombono, ukudideka, ubunzima bokukhuluma noma ukuqonda, ikhanda elibuhlungu kakhulu, ukungazweli noma ubuthakathaka obungazelelwe ebusweni, engalweni, noma emlenzeni. |
| Ukopha noma ukuklwebheka okungavamile | Imivimbo engachazeki, ukopha okungapheli. |
| Imiphumela emibi evame ukungabi mibi kakhulu, kodwa okufanele ibikwe kudokotela uma iqhubeka | |
| Ezinye izifo ezincane | Uhudo, ikhanda elibuhlungu, ukuqaqamba kwemisipha, ukuvuvukala kwamalungu omzimba. |
Lolu hlu aluhlanganisi yonke imiphumela emibi engaba khona. Uma uhlangabezana nanoma yini engavamile, khuluma nodokotela wakho.
Umlayezo Wokuya Nawe Ekhaya
- Qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi, amavithamini, kanye nemikhiqizo yamakhambi oyithathayo.
- Gwema ukuphuza ijusi yamagilebhisi ngenkathi uthatha lo muthi.
- Uma ubona izimpawu zokutheleleka njengomkhuhlane nokukhwehlela, noma ukopha okungajwayelekile noma ukuminyana, funa iseluleko sikadokotela ngokushesha.
- Uma uhlangabezana nezimpawu ezinkulu njengobuhlungu besifuba, ubunzima bokuphefumula, noma ubunzima bokukhuluma, hamba uye eMnyangweni Wezimo Eziphuthumayo (ETU) wesibhedlela ngokushesha.
- Ungalokothi uyeke ukuthatha imithi noma ushintshe umthamo ngaphandle kweseluleko sikadokotela wakho.
- Uma unenkinga ngalo muthi, ungesabi ukukhuluma nodokotela wakho ngawo.
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