Umama wakho, ubaba wakho, noma ngisho nawe ngokwakho cishe uthatha imithi ye-cholesterol, akunjalo? Ama-statin awuhlobo lomuthi odokotela abaluncomayo kubantu abaningi ezweni lakithi. Iningi labantu abasebenzisa le mithi bangaphila kahle ngaphandle kwezinkinga. Kodwa-ke, abanye abantu bangase babe nemiphumela emibi emincane. Ngakho-ke namuhla, sizokhuluma ngezinzuzo zalo muthi kanye nemiphumela emibi engaba khona.
Kalula nje, iyini i-statin?
Ama-statin ayiqembu lemithi evame ukunqunywa odokotela ukusiza ukwehlisa izinga le-cholesterol egazini lethu. Umsebenzi oyinhloko wale mithi ukwehlisa leli zinga le-cholesterol futhi kusivikele ezifweni ezingathi sína njengokuhlaselwa yinhliziyo kanye nesifo sohlangothi. Izifundo zikhombisile ukuthi ukusebenzisa ama-statin kunganciphisa ingozi yokuhlaselwa yinhliziyo, isifo sohlangothi, ngisho nokufa ngenxa yesifo senhliziyo cishe ngo-25%.
Manje, udokotela wakho uzohlola amazinga akho e-cholesterol ngokuhlolwa kwegazi okulula. Uma i-cholesterol yakho "embi", noma i-LDL (Low-Density Lipoprotein) cholesterol iphezulu, usengozini enkulu yesifo senhliziyo. Udokotela wakho angase akunike i-statin, ikakhulukazi uma unezinye izici eziyingozi, njengesifo sikashukela noma umfutho wegazi ophakeme.
Lomuthi usebenza kanjani?
Kalula nje, le mithi ivimba isenzo se-enzyme esiza isibindi sethu ukuthi senze i-cholesterol. Lapho amazinga e-cholesterol egazini lethu enyuka, iqala ukwakheka ezindongeni zemithambo yegazi yethu. Kufana nokugqwala okwakheka ngaphakathi kwepayipi lamanzi elidala. Ngokuhamba kwesikhathi, le mithambo yegazi iyavaleka, futhi ihlule legazi lingabhajwa endaweni evalekile, okungaholela ekuhlaselweni yinhliziyo noma isifo sohlangothi. Ama-statin asiza ukwehlisa i-cholesterol embi (LDL) ngenkathi futhi ekhulisa amazinga e -cholesterol enhle (HDL) , enhle emzimbeni wethu.
Into ebaluleke kakhulu ukuthi ngenkathi uthatha ama-statin, ungathuthukisa imiphumela yemithi ngokulondoloza indlela yokuphila enempilo . Lokho kusho ukudla ukudla okulinganiselayo, ukuzivocavoca umzimba, nokugwema ukubhema.
Yiziphi imiphumela emibi yama-statin?
Nakuba abantu abaningi bengenazo izinkinga, abanye abantu bangase babe nemiphumela emibi. Ungakhathazeki, eminingi yale miphumela ayibi kakhulu.
| Imiphumela Engemihle ye-Statin | |
|---|---|
| Imiphumela Emibi Evamile | |
| Ikhanda elibuhlungu | Ubunzima bokulala |
| Ukuhlanza | Ubuhlungu noma ubuthakathaka bemisipha (i-Myalgia) |
| Ukozela kanye nesiyezi | Ubuhlungu besisu, ukuqunjelwa |
| Uhudo noma ukuqunjelwa | Ukuqubuka kwesikhumba |
| Imiphumela Engavamile Engavamile | |
| Isicanucanu nokulahlekelwa izinwele | Ukuba ndikindiki ezithweni zomzimba |
| Ukuvuvukala kwesibindi (kungase kuzwakale njengomkhuhlane) | Izinkinga ezinjengokungasebenzi kahle kocansi |
Kukhona futhi izixwayiso zokuthi ama-statin angabangela ingozi encane kakhulu yezimo ezifana nokulahlekelwa yinkumbulo, ukudideka kwengqondo, amazinga aphezulu kashukela egazini, kanye nesifo sikashukela sohlobo lwesibili. Sizoxoxa ngalokhu kabanzi.
Imiphumela emibi emibi kakhulu, kodwa engavamile kakhulu
Kubalulekile ukuqaphela lezi zinto, kodwa futhi kudingeka ukhumbule ukuthi lezi zinto zenzeka kaningi kakhulu .
- I-Myositis: Lokhu ukuvuvukala kwemisipha, okungabangela ukuvuvukala. Le ngozi inganda kancane uma ama-statin ethathwa neminye imithi ethile.
- I-Rhabdomyolysis: Lokhu kuyisifo esibi kakhulu, futhi esingavamile kakhulu.Imiphumela emibi. Lokhu kwenzeka lapho amangqamuzana esibindi onakala kakhulu, futhi amaprotheni akhishwa kuwo aqoqana egazini futhi alimaze izinso. Lokhu kungaholela ekuhlulekeni kwezinso. Kodwa ungakhathazeki, lesi simo asivamile kakhulu, sithinta umuntu oyedwa kuphela kwabayizinkulungwane eziyishumi abathatha ama-statin.
Okubaluleke kakhulu: Uma uzwa ubuhlungu obungachazeki, obungavamile, ukuqina, noma ubuthakathaka emisipheni noma emalungeni akho ngenkathi uthatha ama-statin , shayela udokotela wakho ngokushesha umtshele.
Ukwesaba okuvamile kanye nezinganekwane mayelana nama-statin
1. Ingabe ama-statin abangela ukulahlekelwa yinkumbulo? Ingabe abangela ukuwohloka komqondo?
Kwakunehlebezi esikhathini esithile esidlule lokuthi ama-statin angabangela i-dementia. Kodwa ucwaningo eminyakeni engama-20 edlule lukhombisile ukuthi lokhu kungamanga ngokuphelele. Eqinisweni, ezinye izifundo zibonisa ukuthi ukuthatha ama-statin empeleni kunganciphisa ingozi ye-dementia kwabanye abantu.
2. Ingabe kukhona ukuxhumana phakathi kwama-statin nesifo sikashukela?
Lokhu kuyinkimbinkimbi kancane. Abantu abanesifo sikashukela basengozini enkulu yesifo senhliziyo, ngakho odokotela bavame ukubanika ama-statin. Kodwa-ke, ama-statin anengozi encane yokwenyuka kancane kwamazinga kashukela egazini. Lokhu kuvame kakhulu kubantu abanesifo sikashukela sangaphambi kwesikhathi. Njengoba le ngozi incane kakhulu, izinzuzo zama-statin kubantu abanesifo sikashukela zinkulu kakhulu. Kodwa kungcono ukukhuluma nodokotela wakho ngalokhu ngaphambi kokwenza isinqumo.
Ukudla neminye imithi engahambisani nalo muthi
Ama-statin angasebenzisana nokudla okuthile kanye neminye imithi, okungandisa ingozi yemiphumela emibi.
- I-Grapefruit: Lokhu kuyinto abantu abaningi abangazi. Ikhemikhali elikujusi we-grapefruit lingashintsha indlela amanye ama-statin ahlukaniswa ngayo emzimbeni. Lokhu kungenza umuthi usebenze kahle futhi kubangele imiphumela emibi. Uma uthanda ukudla noma ukuphuza i-grapefruit, khuluma nodokotela wakho mayelana nokuthi ingabe lokhu kungathinta uhlobo lwe-statin oluthathayo.
- Eminye imithi: Ama-statin angasebenzisana nemithi yokuphazamiseka kwenhliziyo, eminye imithi yokwehlisa i-cholesterol, eminye imithi elwa namagciwane, kanye nemithi ye-HIV.
Ngakho-ke, kubalulekile ukuthi wazise udokotela wakho ngayo yonke imithi oyithathayo, hhayi nje leyo oyinikezwe udokotela wakho, kodwa nanoma yini oyithengayo ekhemisi, okuhlanganisa imithi yobuhlungu, amavithamini, imithi yendabuko, kanye nemithi ye-Ayurvedic.
Yini okufanele uyenze uma kuvela imiphumela emibi?
Uma uhlangabezana nanoma yimiphi imiphumela emibi, ungayeki ukuthatha umuthi ngokuzumayo. Kunalokho, khuluma nodokotela wakho. Angase akwazi ukukunikeza izixazululo ezifana nalezi:
- Yeka ukuthatha umuthi izinsuku ezimbalwa bese ubona ukuthi lezi zimpawu zibangelwa yiwo ngempela yini umuthi.
- Shintsha uhlobo lwe-statin olunikezwayo.
- Nciphisa umthamo womuthi.
- Cabanga ngolunye uhlobo lomuthi wokwehlisa i-cholesterol.
Abanye abantu bathatha isithasiselo esibizwa ngokuthi i-Coenzyme Q10 (CoQ10) ngenxa yobuhlungu bemisipha. Nakuba abanye bekholelwa ukuthi lokhu kungasiza ekunciphiseni ubuhlungu, akukafakazelwa ngokwesayensi ukuthi kusebenza kahle ngokuphelele. Uma ucabanga ukusebenzisa into efana nale, qiniseka ukuthi ukhuluma nodokotela wakho ngakho.
Umlayezo Wokuya Nawe Ekhaya
- I-Statin iwumuthi obaluleke kakhulu osiza ekunciphiseni i-cholesterol futhi usindise izimpilo ekuhlaselweni yinhliziyo kanye nohlangothi.
- Iningi labantu alibi nemiphumela emibi. Imiphumela emibi abanye abantu abayitholayo ngokuvamile ayibi yingozi.
- Uma uzwa ubuhlungu obungavamile emisipheni noma emalungeni akho, tshela udokotela wakho ngokushesha.
- Ungalokothi uyeke ukuthatha imithi yakho ngaphandle kokubonisana nodokotela wakho .
- Imiphumela emihle kakhulu ingatholakala ngokuphila impilo enempilo ngokudla okuhle nokuzivocavoca umzimba ngenkathi uthatha imithi.
- Ungakhohlwa ukutshela udokotela wakho nganoma yimiphi eminye imithi noma amavithamini owaphuzayo.
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