Uke wezwa ngalo mdlavuza ongavamile? Ake sifunde nge-Signet Ring Cell Carcinoma

Wake wezwa ngohlobo lomdlavuza olubizwa ngokuthi "i-Signet Ring Cell Carcinoma"? Mhlawumbe leli gama lizwakala lingavamile. Kodwa lolu uhlobo lomdlavuza okudingeka sonke siluqaphele. Ngoba uhlobo lomdlavuza olusakazeka ngokushesha, okungukuthi, olunolaka . Ngakho-ke, ake sikuqonde lokhu ngokuningiliziwe namuhla, njengokungathi sikhuluma nomngane.

Kuyini i-Signet Ring Cell Carcinoma?

Kalula nje, i-Signet Ring Cell Carcinoma (SRCC) uhlobo lomdlavuza. Ivame ukuqala emgudwini wakho wokugaya ukudla , ikakhulukazi esiswini sakho. Ithola igama layo elingavamile ngenxa yendlela la maseli omdlavuza abukeka ngayo ngaphansi kwe-microscope. Abukeka njengendandatho, kodwa uhlangothi olulodwa lude kancane, njenge-"signet ring" eyayisetshenziswa ukuvala izinhlamvu ezinsukwini zakudala.

Lo mdlavuza, obizwa ngokuthi "i-SRCC", ungowesigaba somdlavuza obizwa ngokuthi "i-Adenocarcinoma." Lokhu kusho ukuthi lo mdlavuza uvela kumaseli atholakala ezindlaleni zomzimba wethu, esiwabiza ngokuthi amaseli ezindla . Empeleni lawa uhlobo lweseli elivamile elitholakala ezicutshini ezingaphakathi kwezitho zethu.

Kodwa-ke, ukutholakala une-SRCC kungaba yinselele kancane. Lona umdlavuza okhula ngokushesha kakhulu, ngakho-ke ukwelashwa kudinga ukuqala ngokushesha okukhulu. Kodwa-ke, abacwaningi basasebenza ukuthola ukwelashwa okungcono kakhulu kwalesi simo. Uma unalesi simo, kuzodingeka usebenzisane nodokotela wakho womdlavuza ukuze uthole uhlelo lokwelashwa olungcono kakhulu.

Ingabe kunezinhlobo ezahlukene zalo mdlavuza?

Yebo, odokotela bahlukanisa le `(SRCC)` ngokuya ngokuthi umdlavuza uqala kusiphi isitho. Isikhathi esiningi, okungukuthi, cishe amaphesenti angama-90 e-`(SRCC)` avela njengomdlavuza wesisu . Akuvamile kakhulu, ukuthi iqala kwezinye izingxenye zomzimba lapho kukhona khona amaseli ezindlala.

Isibonelo, u-1% noma ngaphansi komdlavuza ezithweni ezilandelayo kutholakale ukuthi "yi-(SRCC)":

• Umdlavuza wamathumbu amakhulu
• Umdlavuza we-rectal
• Umdlavuza we-pancreatic
• Umdlavuza wesinye
• Umdlavuza wenyongo
• Umdlavuza we-Esophageal
• Umdlavuza wesithasiselo
• Umdlavuza we-prostate
• Umdlavuza webele

Uvame kangakanani lo mdlavuza obizwa ngokuthi ``(SRCC)''?

Manje bheka, amaphesenti angama-90-95 omdlavuza wesisu angowohlobo lwe-"Adenocarcinomas". Kulawo mdlavuza wesisu ohlobo lwe-"Adenocarcinomas" , aphakathi kwama-35% nama-40% yi-"SRCC" .

Umdlavuza wesisu ungowesihlanu ovame kakhulu emhlabeni. Kodwa-ke, ukwanda komdlavuza wesisu kuye kwehla uma kuqhathaniswa nesikhathi esidlule. Lokhu kungenxa yokutholakala kwezindlela zokwelapha ezintsha ezingavimbela izinto ezifana nokutheleleka ngebhaktheriya i-Helicobacter pylori (H. pylori), okuyisici esiyingozi somdlavuza wesisu.

Kodwa ngokumangalisayo, inani lomdlavuza wesisu otholakale njengo-"(SRCC)" liyakhula. Ososayensi abakaqiniseki ukuthi kungani.

Ziyini izimpawu zalo mdlavuza? Ingabe kunzima ukubona kusenesikhathi?

Nakhu okufanele ukuqaphele. Izimpawu ze-SRCC zivame ukuvela ngemva kokuba umdlavuza ususakazeke . Ngakho-ke, abantu abaningi abaqapheli ukuthi banenkinga ezigabeni zokuqala. I-SRCC eqala esiswini ivame ukusabalala iye e-peritoneum, emathanjeni, kanye nakwabesifazane, ema-ovari.

Izimpawu ze-`(SRCC)` zingafaka:

• Ukuqunjelwa, ukungagayi kahle kokudla
• Ubuhlungu besisu
• Isicanucanu nokuhlanza
• Uhudo
• Indle enegazi
• Ukukhathala okuvamile
• Ubuhlungu bamalunga
• Ubuhlungu benhliziyo, ukushaya kwenhliziyo okusheshayo, kanye nobunzima bokuphefumula

Cabanga nje, umngane wakho unesifo sesisu esingapheli kanye nesisu esibuhlungu ngemva kokudla. Angase acabange, "O, lokhu kumelwe kube yisifo sofuba esivamile." Kodwa eziningi zalezi zimpawu zingabonakala nasezifweni zesisu ezingatheni kangako njengomdlavuza. Ngakho ungesabi ukuthi umdlavuza ngoba nje unalezi zimpawu. Kodwa-ke, uma unezimpawu eziqhubekayo nezingelapheki, kuhlale kuwukuhlakanipha ukubona udokotela.

Kungani lolu hlobo lomdlavuza luvela? Iyini imbangela?

I-SRCC ikhula lapho amangqamuzana ezindlala angajwayelekile eqala ukuzakhela amakhophi. Lawa maseli angajwayelekile angakha amathumba, asakaze, futhi abhubhise izicubu ezinempilo. Kodwa-ke, abacwaningi abakaqiniseki ukuthi kungani amangqamuzana ahilelekile ku-SRCC eba angajwayelekile kwasekuqaleni.

Ezinye izifundo zibonise ukuthi izinguquko ku-gene ebizwa ngokuthi i-CDH1, eyenza iphrotheni ebalulekile kumaseli ezindlala, zingadlala indima. Kodwa-ke, kusekuningi okusazotholakala mayelana nendlela amaseli ezindlala (SRCC) aba ngayo amabi.

Odokotela bawuthola kanjani lo mdlavuza '(SRCC)'?

Ukuxilongwa kwe-(SRCC) kuvame ukuqala ngodokotela ebuza ngezimpawu zakho futhi enze ukuhlolwa ngokomzimba. Lokhu kungabasiza bathole umbono wokuthi inkinga ikuphi emzimbeni wakho. Banganquma ukuthi yiziphi izivivinyo okufanele bazenze. Lezi zivivinyo zingafaka:

• Ukuhlolwa kwezithombe:I-computed tomography (CT) scan ivame ukusetshenziswa ukuthola izimila endleleni yokugaya ukudla. Uma udokotela wakho ethola isimila esisolisayo, angase futhi acele i-PET scan ukuze abone ukuthi amaseli omdlavuza asakazekile yini.
• Ukuhlolwa kwegazi: Kuzothathwa isampula yegazi lakho futhi kuzokwenziwa ukuhlolwa okuningana. Lokhu kungafaka phakathi ukuhlolwa kokuhlola impilo yakho jikelele, kanye nokuhlolwa kokuhlola izimpawu zezifo ezifana nomdlavuza.
• I-Biopsy: Lolu vivinyo olubaluleke kakhulu . Udokotela kuzodingeka athathe isampula yalo lonke umdlavuza noma izicubu bese elihlola. Lena yindlela udokotela azoqinisekisa ngayo ukuthi ngabe yi-SRCC. Udokotela wezifo uzobheka isampula ngaphansi kwe-microscope ukuze abone ukuthi kukhona yini amaseli "endandatho yophawu". Bangenza nokuhlolwa okukhethekile okubizwa ngokuthi i-immunohistochemistry kusampula ukuqinisekisa ukuthi amaseli anomdlavuza.

Kungelashwa kanjani lokhu? Ingabe kungelapheka?

Ukwelashwa okutholayo kuncike ezintweni eziningi. Okuyinhloko ukuthi umdlavuza uqale kuphi (uhlobo) nokuthi ususakazeke kangakanani (isigaba). Konke lokhu kunqunywa ngemva kokukhuluma nodokotela wakho. Abantu abaningi abane-(SRCC) badinga ukwelashwa okungaphezu kokukodwa, noma inhlanganisela yokwelashwa . Lokhu kungafaka:

• Ukuhlinzwa kwe-Endoscopic: Uma umdlavuza ungakasabalali, ukuhlinzwa kungenziwa kusetshenziswa indlela ebizwa ngokuthi i-esophagogastroduodenoscopy. Lokhu kuhilela ukususa isimila ngepayipi elifakwe ngomlomo. Lena inqubo engahlaseli.
• Ukususwa Okukhulu: Lena inqubo yokuhlinzwa evame kakhulu ye-SRCC. Lokhu kungenxa yokuthi umdlavuza uvame ukuba sezingeni eliphezulu uma utholakala. Lokhu kuhilela ukususa lonke isimila kanye nezicubu ezizungezile. Njengoba i-SRCC ivame ukusabalala iye kuma-lymph node, odokotela basusa namanye ama-lymph node.
• I-Hyperthermic Intraperitoneal Chemotherapy (HIPEC): Lokhu kuyinhlanganisela yokuhlinzwa kanye ne-chemotherapy yokwelapha umdlavuza osakazeke ngaphakathi kwesisu. Ngemva kokuba udokotela esuse isimila, imithi ye-chemotherapy ifakwa ngqo esiswini. Imithi bese iyashiswa. Ukushisa kwenza imithi ye-chemotherapy ibe nobuthi kakhulu kunoma yimaphi amangqamuzana omdlavuza asele.
• I-chemotherapy yesistimu: Udokotela wakho angase futhi ancome le ndlela. Lapha, unikezwa imithi ye-chemotherapy, kungaba ngamaphilisi noma njenge-IV. Le mithi ihamba emzimbeni wakho wonke futhi ibulale amangqamuzana omdlavuza. Nakuba i-chemotherapy iyindlela yokwelapha evamile (i-SRCC), ingase ingasebenzi kahle esikhathini eside.
• Ukwelashwa ngemisebe:Abanye odokotela batusa kokubili ukwelashwa ngemisebe kanye ne-chemotherapy ukubulala noma yimaphi amangqamuzana omdlavuza asele ngemva kokuhlinzwa. Ukwelashwa ngemisebe (SRCC) kusebenzisa umshini ongaphandle komzimba ukuqondisa amandla kumaseli omdlavuza.
• Izivivinyo zemitholampilo: Lezi zenzelwe ukuhlola ukuphepha nokusebenza kahle kwezindlela ezintsha zokwelapha umdlavuza. Ososayensi bayaqhubeka nokufunda ngezinguquko zamaseli eziholela ku-(SRCC), ngenhloso yokuthuthukisa izindlela zokwelapha ezingamisa lezi zinguquko. Ukubamba iqhaza esivivinyweni semitholampilo kungakunika ithuba lokuthola lezi zindlela zokwelapha ezintsha.

Uma ngine-`(SRCC)`, yiziphi izinto engizobhekana nazo?

Eqinisweni, akekho ongabikezela ngqo ukuthi ulwazi lomuntu nge-SRCC luzoba njani. Kodwa esikwaziyo ukuthi uma kuqhathaniswa nezinye izinhlobo ze-carcinoma, i-SRCC ingumdlavuza onolaka kakhulu, okhula ngokushesha . Kungenzeka ukuthi ibuye futhi ngemva kokuhlinzwa. Kunzima futhi ukulawula isikhathi eside ngemithi ejwayelekile yomdlavuza efana ne-chemotherapy.

Okuhlangenwe nakho kwakho kuzoncika kakhulu emigomweni yakho. Uma umdlavuza usesigabeni sokuqala, umgomo kungaba ukwelapha umdlavuza ngokuphelele nokuwugcina "uphilile." Uma umdlavuza ususakazeke, njengasesigabeni sesi-4, ukwelashwa kungakusiza ukuthi uphile ngokunethezeka.

Buza udokotela wakho ukuthi yini ongayilindela ngokusekelwe ekuxilongweni kwakho.

Ngingazinakekela kanjani? Ngingenzani?

Kubalulekile ukufunda okuningi ngangokunokwenzeka mayelana nokuxilongwa kwakho (i-SRCC). Kungcono ukuthola izimpendulo zemibuzo (noma ngabe zinzima) kunokukhathazeka ngokuthi kwenzekani emzimbeni wakho. Buza udokotela wakho ukuthi ukuxilongwa kwakho kuzothinta kanjani impilo yakho yonke kanye nokuphila kwansuku zonke.

Futhi, buza udokotela wakho ukuthi ungazuza yini ezinsizakalweni zokunakekelwa kobuhlungu. Umgomo wokunakekelwa kobuhlungu ukuhlinzeka impumuzo ezimpawini. Kungakhathaliseki ukuthi umdlavuza wakho ukusiphi isigaba, lezi zinsizakalo zingasiza ekunciphiseni izimpawu zomdlavuza kanye nemiphumela emibi yokwelashwa.

Kufanele ngimbone nini udokotela?

Uma unezimpawu zesisu ezingapheli, ezingachazeki - isibonelo, ubuhlungu besisu noma isifo sohudo - bona udokotela. Ngokuvamile, lezi zingaba izimpawu zesimo esingesibi kangako. Akuvamile kakhulu , zingaba izimpawu zesimila esiswini.

Kufanele ngiye nini e-Emergency Treatment Unit (ETU) ?

Uma unezimpawu ezifana nesiyezi, umkhuhlane, kanye nobunzima bokuphefumula (ukuphelelwa umoya), iya ekamelweni lezimo eziphuthumayo ngokushesha. Lezi zimpawu zivame ezimweni eziningi ezidinga ukwelashwa okuphuthumayo, okuhlanganisa nobunzima obukhulu (SRCC).

Yimiphi imibuzo okufanele ngiyibuze udokotela wami?

Kubalulekile ukuqonda konke mayelana nokuxilongwa kwakho, okuhlanganisa nokuthi kuthinta kanjani impilo yakho yansuku zonke. Ungabuza imibuzo efana nale:

• Uhlobo luni lomdlavuza enginalo?
• Umdlavuza wami ukusiphi isigaba?
• Yikuphi ukwelashwa okuncomayo?
• Yimiphi imiphumela emibi engingayilindela ekwelashweni?
• Iyini imiphumela yami yokwelashwa?
• Yiziphi izinyathelo engingazithatha ukuze ngiphile ne-`(SRCC)` kube lula?

Okokugcina, izinto okufanele uzikhumbule

Ukwazi ukuthi umdlavuza wakho uyi-signet ring cell carcinoma (SRCC) kubalulekile kodokotela abancoma ukwelashwa ngokusekelwe kuhlobo lomdlavuza. Kodwa umbuzo omkhulu kubantu abaningi ungaba: "Lokhu kuzoyithinta kanjani impilo yami?" Impendulo ayilula. Ukuba nayo (SRCC) kusho ukuthi kungadingeka wenze izinqumo ezinzima mayelana nezinketho zakho zokwelashwa. Ungadinga usizo lokuqonda ukuthi ukuxilongwa kwakho kuzoshintsha kanjani impilo yakho yansuku zonke.

Ungesabi, khuluma nodokotela wakho ucele usizo. Ungumuntu ongcono kakhulu ukuchaza ukuthi yiziphi izinyathelo ongazithatha ukuze uphathe okuzayo. Khumbula, awuwedwa.

I- Carcinoma Yeseli Lendandatho Yesignali, i-SRCC, Umdlavuza Wesisu, Izimpawu Zomdlavuza, Ukwelashwa Komdlavuza, i-Adenocarcinoma, Umdlavuza Wesisu