Uyazi nge-capsule ye-Sonidegib (Odomzo) yomdlavuza wesikhumba?

Kuvamile ukuthi ukwesaba okuncane nokukhathazeka kufike engqondweni yakho uma uzwa amagama athi umdlavuza wesikhumba. Kodwa sinenhlanhla, ngoba ngesayensi yezokwelapha ethuthukisiwe namuhla, kunezindlela zokwelapha eziphumelelayo kakhulu zezifo ezinjalo. I-Sonidegib umuthi wesimanje osetshenziselwa ukwelapha uhlobo olunjalo lomdlavuza wesikhumba, ikakhulukazi i-'Basal Cell Carcinoma'. Ngakho-ke namuhla, ake sixoxe ngalo muthi ngamagama alula, ukuthi ungawusebenzisa kanjani, okufanele uqaphele ngakho, kanye nayo yonke imiphumela emibi.

Uhlobo luni lomuthi iSonidegib?

Kalula nje, lolu uhlobo lomuthi olubizwa ngokuthi "ukwelashwa okuqondiwe." Lokhu kusho ukuthi lo muthi uhlose amangqamuzana omdlavuza kuphela futhi uvimba ukukhula kwawo, ngaphandle kokulimaza amangqamuzana anempilo. Ngokuvamile uzothola lokhu emakethe ngaphansi kwegama lomkhiqizo i-Odomzo. Usetshenziswa kakhulu ukulawula uhlobo lomdlavuza wesikhumba olubizwa ngokuthi i-'Basal Cell Carcinoma.'

Izinto okudingeka uzitshele udokotela wakho ngaphambi kokuqala imithi

Ngaphambi kokuqala lokhu kwelashwa, kubaluleke kakhulu ukwazisa udokotela wakho ngokucacile ngalokhu okulandelayo:

• Kungakhathaliseki ukuthi uke waba nezinkinga zemisipha ngaphambili.
• Kungakhathaliseki ukuthi kukhona ukusabela kokungezwani komzimba nomuthi i-Sonidegib noma yimuphi omunye umuthi, ukudla, noma idayi.
• Uma uzama ukukhulelwa, noma ukhulelwe njengamanje, lokhu kuyinto okumele uyisho. Leli iphuzu elibaluleke kakhulu.
• Uma ungumama oncelisayo, sicela usazise futhi.

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Ngiyisebenzisa kanjani ngempela le mithi?

Ukuze uthole okuningi kulo muthi, kubalulekile ukuwusebenzisa njengoba kuqondiswe.

• Lomuthi kufanele ugwinywe uphelele ngengilazi yamanzi .
• Ungalokothi uphule, uchoboze, noma uhlafune le capsule. Ukwenza kanjalo kungathinta ukusebenza kahle komuthi.
• Lokhu kufanele kuthathwe esiswini esingenalutho . Okusho ukuthi, ihora elilodwa ngaphambi noma amahora amabili ngemva kokudla. Ungakuthathi lokhu kanye nokudla.
• Enye into ebalulekile ukugwema ukuthatha lo muthi kanye nejusi lamagilebhisi.
• Thatha umuthi wakho nsuku zonke, njengoba uyalelwe, ngesikhathi udokotela wakho akuyalele sona. Ungayeki ukuthatha umuthi wakho ngaphandle kweseluleko sikadokotela wakho.
• Uma unikezwe lo muthi, uzothola incwajana yolwazi ekhethekile (i-MedGuide) ngawo. Kubalulekile ukuwufunda nokuwuqonda ngokucophelela isikhathi ngasinye.

Uma uphuthelwa umthamo wemithi ngokuzumayo, ungesabi. Khohlwa umthamo ophuthelwe bese uthatha umthamo olandelayo njengokujwayelekile ngosuku olulandelayo ngesikhathi esihleliwe. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ngoba nje ukhohliwe.

Kuthiwani uma ngiphuza kakhulu?

Uma ucabanga ukuthi uthathe umuthi omningi kakhulu, shayela ngokushesha iNational Poisons Information Centre eColombo National Hospital, noma uye e-Emergency Treatment Unit (ETU) yesibhedlela esiseduze.

Izinto okufanele uziqaphele kakhulu lapho uthatha imithi

Naka kakhulu la maphuzu ukuze uphephe futhi uphumelele ekwelashweni kwakho ngenkathi uthatha lo muthi.

• Ukukhulelwa nokuncelisa (kwabesifazane): Lena yinto ebaluleke kakhulu. Ungakhulelwa nganoma yisiphi isizathu ngenkathi uthatha lo muthi. Futhi, kufanele ugweme ukukhulelwa izinyanga ezingama-20 ngemuva kokuyeka umuthi. Lo muthi ungabangela ukukhubazeka okukhulu kokuzalwa noma ngisho nokufa enganeni engakazalwa. Kufanele uhlolwe ukuqinisekisa ukuthi awukhulelwe ngaphambi kokuqala umuthi. Uma ungumama oncelisayo, ungancelisi ngenkathi uthatha umuthi futhi izinyanga ezingama-20 ngemuva kokuyeka umuthi.

• Kwabesilisa abafuna ukuba ngubaba wengane: Gwema ukuba ngubaba wengane ngenkathi uthatha lo muthi kanye nezinyanga ezingu-8 ngemuva kokuwuyeka. Uma uya ocansini phakathi nalesi sikhathi , kufanele usebenzise ikhondomu ye-latex. Lokhu kuyadingeka noma ngabe uke wahlinzwa i-vasectomy. Uma umlingani wakho ekhulelwa, tshela udokotela wakho ngokushesha. Futhi, gwema ukunikela ngesidoda ngenkathi uthatha lo muthi kanye nezinyanga ezingu-8 ngemuva kokuwuyeka.

• Ukunikela Ngegazi: Unganikeli ngegazi ngenkathi uthatha umuthi futhi izinyanga ezingama-20 ngemuva kokuqeda ukwelashwa. Uma igazi linikezwa owesifazane okhulelwe, angase abhekane nalo muthi.

• Ukuhlolwa kwezokwelapha: Udokotela wakho uvame uku-oda ukuhlolwa kwegazi ukuze abone ukuthi umuthi uwuthinta kanjani umzimba wakho ngenkathi uthatha lo muthi. Qiniseka ukuthi wenza lokhu kuhlolwa njalo.

Imiphumela emibi engase ivele ngenxa yemithi

Njenganoma yimuphi umuthi, i-Sonidegib ingabangela imiphumela emibi. Eminye yale miphumela ingaba mibi kakhulu, ngakho-ke kubalulekile ukuyiqaphela.

Uma uhlangabezana nanoma yiziphi ezinye izimpawu ezingavamile ezingashiwongo kulolu hlu, khuluma nodokotela wakho ngazo futhi.

Eminye imithi engase ihlangane nalo muthi (Ukusebenzisana Kwezidakamizwa)

'Ukuxhumana kwezidakamizwa' yilapho umuthi owodwa esiwuthathayo uthinta isenzo somunye umuthi esiwuthathayo. Ngakho-ke, kubaluleke kakhulu ukutshela udokotela wakho ngayo yonke imithi oyithathayo. Eminye yemithi engase ihlangane ne-Sonidegib ibhalwe ngezansi.

• Eminye imithi yokwelapha izifo zesikhunta (isib. i-ketoconazole, i-itraconazole, i-fluconazole)
• Eminye imithi yesifo sokuwa (isib. i-carbamazepine, i-phenytoin)
• Imithi efana ne-atazanavir ne-saquinavir
• Ama-antibiotic afana ne-erythromycin ne-telithromycin
• I-Rifampin, i-rifabutin
• Imithi yokulawula i-asidi yesisu (isib. i-omeprazole, i-famotidine)
• Imikhiqizo yamakhambi njenge-St. John's Wort

Lolu hlu aluphelele. Ngakho-ke, tshela udokotela wakho nganoma yimiphi imithi, amavithamini, noma imithi yendabuko oyithathayo. Futhi, ungakhohlwa ukutshela udokotela wakho uma ubhema noma uphuza utshwala.