Kungenzeka ukuthi awukaze uzwe nge-SAM-e (ebizwa ngokuthi i-SAM-e) ngaphambili. Kodwa bewazi, lokhu kuyikhemikhali ebaluleke kakhulu ekhiqizwa ngokwemvelo emzimbeni wakho, owakho nowami, njalo ngomzuzwana wosuku. Kalula nje, kubalulekile ekusebenzeni okuvamile kwemizimba yethu. Imizimba yethu iyikhiqiza njalo, nsuku zonke, njalo ngomzuzwana.
Yini ngempela eyenziwa yi-SAM-e emizimbeni yethu?
Ake sithi umzimba wethu uyinkampani enkulu. Umsebenzi ngamunye kule nkampani udinga ukuthumela imiyalezo. 'Izithunywa' ezithwala le miyalezo phakathi kwamangqamuzana ezinzwa yilokho esikubiza ngokuthi ama-neurotransmitter . Kufana nomuntu ohambisa izincwadi ehhovisi. Ngakho-ke kunenqubo ebaluleke kakhulu eyenzeka kuwo wonke umzimba esiza ekwenzeni la ma-neurotransmitter, futhi sikubiza ngokuthi i-methylation . Umsebenzi oyinhloko we-SAM-e ukusiza ngale nqubo ye-methylation.
Nakuba imizimba yethu ikhiqiza lokhu, ngezinye izikhathi kungase kunganeli. Yilapho abanye abantu bekusebenzisa khona njengesithasiselo . Nakuba kutholakala njengesithasiselo emazweni anjengeMelika, futhi kunikezwa njengomuthi kadokotela kwamanye amazwe aseYurophu. Igama layo lesayensi yi-S-adenosylmethionine.
Pho kungani abantu besebenzisa i-SAM-e?
Abantu abaningi bakhetha ukusebenzisa into ezwakala 'njengeyemvelo' futhi 'ethambile kancane' kunemithi yendabuko yaseNtshonalanga. Ngoba bacabanga ukuthi njengoba kuyinto ekhiqizwa ngumzimba ngokwawo, ngeke kube nemiphumela emibi emikhulu. Kulabo bantu, i-SAM-e iyindlela ehlukile ekhangayo.
I-SAM-e ixoxwa kakhulu ngokuphathelene nezimo ezimbili zezokwelapha: i-osteoarthritis kanye nokucindezeleka.
I-Osteoarthritis
Ezinye izifundo zithole ukuthi i-SAM-e ingasiza ekunciphiseni ubuhlungu, ikakhulukazi obubangelwa yi-osteoarthritis yedolo noma i-hip. Ezinye izifundo zibonise ukuthi i-SAM-e isebenza kahle njengemithi elwa nokuvuvukala engeyona i-steroidal (ama-NSAID) njenge -ibuprofen noma i-celecoxib ekunciphiseni ubuhlungu nasekuthuthukiseni ukuhamba kwamalunga. Nakuba ingase ingasebenzi ngokushesha njengemithi, kuthiwa futhi inemiphumela emibi embalwa . Lokhu kungenxa yokuthi i-SAM-e inganciphisa umsebenzi wamakhemikhali athile emzimbeni abangela ukuvuvukala nobuhlungu.
Ngokucindezeleka
Abanye abantu abanesifo sokucindezeleka kutholakale ukuthi banamazinga aphansi e-SAM-e. Amanye ama-antidepressant ahlasela ama-neurotransmitter ebuchosheni, njenge -serotonin , i-norepinephrine , kanye ne-dopamine .Abacwaningi bakholelwa ukuthi i-SAM-e ingavuselela futhi.
Kodwa iningi lezifundo ezenziwe ngalokhu zincane futhi zesikhashana. Ngakho -ke akukakafakazelwa ngokugcwele ukuthi kusebenza kahle kangakanani ekucindezelekeni. Nakuba abanye abantu basebenzisa i-SAM-e kanye nemithi yokucindezeleka, akukho nzuzo ecacile yokwenza kanjalo.
Into ebalulekile ukuthi i-SAM-e ayiyona into ewumlingo. Uma uyisebenzisa, kufanele ibe yingxenye eyodwa kuphela yohlelo lokwelashwa oluphelele. Okusho ukuthi, kufanele ihambisane nezinye izindlela zokwelapha, njengokudla nokuzivocavoca.
Ngaphezu kwalokhu okubili, abanye abantu bayisebenzisela nezimo ezifana ne -intrahepatic cholestasis , isifo sika-Alzheimer , i-fibromyalgia , kanye ne-migraine , kodwa ucwaningo alukabi khona olwanele ngalokhu okwamanje.
Uma ngisebenzisa i-SAM-e, kufanele ngithathe malini?
Akukho mthamo othize walokhu. Kuyahlukahluka kumuntu nomuntu, kuye ngesifo. Isibonelo, ama-milligram angu-400-600 ngosuku okucindezeleka, kanye nama-milligram angu-600-1200 ngosuku (ahlukaniswe ngemithamo emithathu) we- osteoarthritis asetshenziswe ezifundweni.
Kodwa kufanele nakanjani ukhulume nodokotela wakho mayelana nokuthi lokhu kulungile yini kuwe nokuthi kufanele uthathe malini. Udokotela wakho angase akucebise ukuthi wandise kancane kancane umthamo ukuze unciphise imiphumela emibi efana nokungahlaliseki nokukhathazeka .
Ingabe kukhona ingozi ekusebenziseni lokhu?
I-SAM-e ibhekwa njengephephile, kodwa izifundo eziningi bezingokwesikhashana, ngakho-ke abukho ubufakazi obuncane bokuphepha kwayo ekusetshenzisweni kwesikhathi eside.
Imiphumela emibi ngokuvamile ayibi mibi kakhulu. Imiphumela emibi evame kakhulu yile:
| Imiphumela Emibi Evamile Ye-SAM-e | |
|---|---|
| - Ukuphazamiseka kwesisu, isicanucanu | - Uhudo noma ukuqunjelwa |
| - Umlomo owomile | - Ikhanda elibuhlungu kanye nesiyezi |
| - Ukukhathazeka nokungaphumuli | - Ukujuluka |
| - Ukuqunjelwa (igesi) | - Ukungalali |
Izimo okufanele uziqaphele kakhulu
Abanye abantu bangase bacabange ukuthi ukuthatha lokhu ngaphandle kokukhuluma nodokotela kulungile ngoba imiphumela emibi mincane kakhulu. Kodwa lelo yiphutha elikhulu. Ukuthatha i-SAM-e kungaba yingozi, ikakhulukazi uma uthatha eminye imithi noma izithasiselo.
| Ubani/nini lapho umuntu kufanele aqaphele khona? | Iyini ingozi? |
|---|---|
| Abantu abathatha ukwelashwa kokucindezeleka (ikakhulukazi labo abathatha eminye imithi yokucindezeleka noma izithasiselo ezifana ne-St. John's wort) | Imiphumela ehlangene yalezi zidakamizwa zombili ingabangela amazinga aphezulu kakhulu e-serotonin emzimbeni (i-Serotonin Syndrome). |
| Abantu abanesifo sokuphazamiseka kwengqondo | Lokhu kungase kube kubi kakhulu esimweni sabo sokusebenza ngokweqile kanye nokujabula (i-Mania/Hypomania). |
| Omama abakhulelwe nabancelisayo | Ngenxa yokuntuleka kwedatha yokuphepha, gwema ukuthatha ngaphandle kwemvume kadokotela wakho. |
| Izingane ezincane | Akukhuthazwa ezinganeni. |
| Abantu abasebenzisa eminye imithi (yokukhwehlela, izinhlungu, isifo sikashukela, isifo sikaParkinson, ama-MAOI) | Iseluleko sezokwelapha sibalulekile njengoba kungase kwenzeke ukusebenzisana okungafuneki nalo muthi. |
Uma uthenga isithasiselo se-SAM-e, qiniseka ukuthi uhlola ikhwalithi yaso. Kungumqondo omuhle ukubheka izimpawu zesitifiketi sekhwalithi njenge-US Pharmacopeia (USP) noma i-Good Manufacturing Practice (GMP) kulebula.
Imibuzo Evame Ukubuzwa (Imibuzo Evame Ukubuzwa)
- Ingabe i-SAM-e ibangela ukulahleka kwezinwele?
Cha, i-SAM-e ayibikwanga ukuthi ibangela ukulahleka kwezinwele.
- Kuthatha isikhathi esingakanani ukubona imiphumela?
Ngokuvamile kuthatha amasonto ambalwa ukuzwa noma yiluphi ushintsho.
- Ingabe i-SAM-e ikwenza ube mkhulu?
Cha, asikho isizathu sokukholelwa ukuthi i-SAM-e ibangela ukukhuluphala.
- Ingabe i-SAM-e ikwenza uzizwe ungcono?
Yebo, uma lokhu kuphumelela ekucindezelekeni, abanye abantu bazizwa sengathi banamandla engeziwe. Lokho kungaba amandla amahle futhi akhiqizayo. Kodwa kwabanye, kungazwakala njengokukhathazeka noma ukungaphumuli.
- Awukwazi yini ukuthola i-SAM-e ekudleni?
Cha, akukho ukudla okuqukethe i-SAM-e. Kuyinto umzimba ozikhiqizayo wona.
Umlayezo Wokuya Nawe Ekhaya
- I-SAM-e iyinhlanganisela eyenzeka ngokwemvelo emizimbeni yethu futhi ibalulekile ekusebenzeni komzimba kanye nesimo sengqondo.
- Nakuba isetshenziswa njengesengezo sokwelapha ubuhlungu bamalunga nokucindezeleka, kusenobufakazi obuncane besayensi bokusebenza kwayo.
- Nakuba imiphumela emibi ivame ukuba mincane, kungaba nezingozi kwabanye abantu futhi uma ithathwa neminye imithi.
- Ungalokothi uqale ukusebenzisa i-SAM-e ngaphandle kweseluleko sezokwelapha, ikakhulukazi uma uthatha imithi yesinye isimo, noma uma ukhulelwe noma uncelisa.
- Njenganoma yisiphi isithasiselo, lokhu kufanele kusetshenziswe kuphela ngaphansi kwesiqondiso sikadokotela wakho.
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