Uma uthola ukuthi othile emndenini wakho, ikakhulukazi ingane encane, unesifo sikashukela, uzizwa wesaba kakhulu futhi ushaqekile, akunjalo? Kufanele ufake i-insulin nsuku zonke, ulawule ukudla kwakho, futhi uhlole ushukela wakho njalo... Sonke siyazi ukuthi kunzima kangakanani ukuphila nezinto ezinjengalezi. Kodwa, endabeni yesifo sikashukela sohlobo 1, manje sekukhona ukwelashwa okusha okungabambezela ukuqala kwezimpawu ngeminyaka eminingana, okungukuthi, ukubambezela ukuqala kwezimpawu, ungakukholwa? Yebo, namuhla sikhuluma ngalelo themba elisha.
Okokuqala, ake sibone, siyini isifo sikashukela sohlobo 1?
Uma kukhulunywa ngesifo sikashukela, abantu abaningi ezweni lethu bayazi ngesifo sikashukela sohlobo 2. Sivame ukubangelwa abantu abadala kanye nendlela yokuphila engaphilile. Kodwa isifo sikashukela sohlobo 1 sihlukile.
Kalula nje, umzimba wethu une-organ ebizwa ngokuthi i-pancreas. Yizinhlayiya ezikhethekile kule pancreas ezikhiqiza i-hormone ebalulekile i-insulin . Umsebenzi we-insulin ukusiza amangqamuzana omzimba ukuthi athathe ushukela (i-glucose) owengezwa egazini ekudleni esikudlayo bese ewusebenzisa ukwenza amandla. Kufana nokuvula umnyango ngesihluthulelo.
Kusifo sikashukela sohlobo 1, amasosha omzimba wethu abhubhisa ngephutha amangqamuzana amahle enza i-insulin. Bese umzimba ungakhiqizi i-insulin oyidingayo. Ngakho-ke, izinga likashukela egazini liyakhuphuka ngendlela engalawuleki. Lokhu kubizwa ngokuthi isifo sikashukela sohlobo 1. Lesi yisimo esingenakwelashwa futhi sidinga imijovo ye-insulin nsuku zonke impilo yonke.
Kungani lokhu kwenzeka? Indlela umzimba ophulukisa ngayo
Cabanga ngomonakalo ongaba khona uma ibutho lezwe lethu lingahlasela ngephutha abantu abangenacala ezweni lakithi. Yilokho okwenzekayo ngesifo sikashukela sohlobo 1. "Ibutho" elivikela imizimba yethu ezifweni, isimiso somzimba sokuzivikela , liyacasuka ngesizathu esithile bese liqala ukubhubhisa amangqamuzana akhiqiza i-insulin kuma-pancreas ethu, licabanga ukuthi "liyizitha." Sibiza lezi zifo lapho umzimba uzihlasela khona izifo zokuzivikela komzimba .
Lokhu akwenzeki konke ngesikhathi esisodwa. Lokhu kubhujiswa kwenzeka kancane, ngezigaba eziningana. Ngokuvamile, ngesikhathi kuvela izimpawu, iningi lamaseli akhiqiza i-insulin lisuke selibhujisiwe kakade.
Izigaba ezintathu zalesi sifo (Izigaba ze-T1D)
Ukuthuthukiswa kwesifo sikashukela sohlobo 1 kungahlukaniswa ngokucacile ngezigaba ezintathu. Lokhu kuzoba lula kuwe ukukuqonda uma ubheka ithebula.
| Isiteji | Kwenzakalani | Izimpawu kanye namazinga kashukela egazini |
|---|---|---|
| Isigaba 1 | Amasosha omzimba aqala ukuhlasela amaseli enza i-insulin, kodwa kusakhiqizwa i-insulin eyanele. | Azikho izimpawu. Amazinga kashukela egazini ajwayelekile. |
| Isigaba sesi-2 | Njengoba ukubhujiswa kwamangqamuzana kuqhubeka, ukukhiqizwa kwe-insulin kuyancipha, okwenza kube nzima ngomzimba ukulawula amazinga kashukela. | Azikho izimpawu ezisobala okwamanje. Kodwa izinga likashukela egazini liphakeme (elingavamile). Lokhu kungatholakala ngokuhlolwa okukhethekile. |
| Isigaba 3 | Inani elikhulu lamaseli akhiqiza i-insulin liyabhujiswa, okwenza kube nzima ngomzimba ukulawula amazinga kashukela. | Izimpawu ezisobala ziyavela. Ukuchama njalo, ukoma ngokweqile, indlala, ukwehla kwesisindo, kanye nokukhathala okukhulu kuyavela. Lesi sifo sivame ukutholakala kulesi sigaba. |
Ithemba Elisha: Umuthi we-Teplizumab (Tzield)
Lokhu kwelashwa okusha okukhulunywe ngakho ekuqaleni kunganikezwa labo abasesigabeni sesi-2, okungukuthi, ngaphambi kokuba kuvele izimpawu, kodwa ushukela wabo egazini uphezulu. Igama lalo muthi yi -Teplizumab (Tzield) .
Kwenzekani ngalo muthi?
Lokhu kufana nomenzi wokuthula. Lo muthi uthinta amasosha omzimba ethu. Ubuthakathaka "amasosha" aziphatha kabi futhi azama ukubhubhisa amangqamuzana akhiqiza i-insulin. Khona-ke lawo maseli anamandla amancane okulimaza ama-pancreas. Ngenxa yalokho, amangqamuzana amahle asele avikelwe isikhathi eside futhi aqhubeke nokukhiqiza i-insulin edingwa ngumzimba.
Lesi sifo singabambezeleka isikhathi esingakanani?
Njengoba ukuhlolwa kwezokwelapha kubonisile, lokhu kwelashwa kuye kwakwazi ukulibazisa ukuqhubekela phambili esigabeni sesi-3, isigaba lapho izimpawu zivela khona, ngesilinganiso seminyaka emibili . Kwabanye abantu, kungalibazisa isikhathi eside nakakhulu.
Iyini inzuzo yangempela yokulibazisa lesi sifo?
Ungase ucabange, "Sekuyiminyaka emibili kuphela, kusho ukuthini lokho?" Kodwa leso sikhathi siyigugu kakhulu, ikakhulukazi empilweni yengane.
- Ukukhululeka emthwalweni wansuku zonke: Ungaphila impilo ejwayelekile eminye iminyaka emibili ngaphandle kokujova i-insulin nsuku zonke, ukuhlaba umunwe wakho ukuhlola ushukela egazini lakho, noma ukukhathazeka ngokudla.
- Inhlalakahle yengqondo: Kumntwana noma kumuntu osemusha, kulokhu ukukhululeka nabangani bakhe, ngaphandle kokucindezeleka kokuthi "Nginesifo sikashukela," kubaluleke kakhulu.
- Ukukhula ngokomzimba: Phakathi nalesi sikhathi sokungabi nazimpawu, ukukhula ngokomzimba nangokwengqondo kwengane kwenzeka ngokujwayelekile ngaphandle kokuphazamiseka.
- Isikhathi sokulungiselela: Ngisho noma lesi sifo singenakugwenywa, umndeni unesikhathi sokubhekana naso, ufunde ngaso, futhi ulungiselele ngokwengqondo nangokomzimba.
- Ukulibazisa izinkinga: Lokhu futhi kubambezela ukuqala kwezinkinga zesikhathi eside (umonakalo wamehlo, wezinso, kanye nemizwa) ezingabangelwa isifo sikashukela.
Ubani lokwelashwa okufanelekelayo nokuthi yini okufanele uyazi
Lokhu akuyona indlela yokwelapha enganikezwa wonke umuntu. Lo muthi okwamanje uvunyelwe:
- Kulabo abaneminyaka engaphezu kwengu-8 ubudala .
- Kulabo abasesigabeni sesi-2 sesifo sikashukela sohlobo 1.
Lokhu akusiqedi lesi sifo ngokuphelele. Kumane nje kubambezele ukuqala kwezimpawu. Futhi, ukuze umuntu athole lokhu kwelashwa, kumele aqinisekiswe ngokuhlolwa kwegazi okukhethekile kungakhathaliseki ukuthi useqenjini eliyingozi noma usesigabeni sesi-2.
Uma ucabanga ukuthi wena noma ingane yakho ningaba sengozini yokuthola isifo sikashukela sohlobo 1 (isibonelo, uma othile emndenini wakho enesifo sikashukela sohlobo 1), kungcono ukukhuluma nodokotela wakho ngalokhu. Angenza izivivinyo ezidingekayo futhi anqume ukuthi lolu hlobo lokwelashwa lukulungele yini. Lesi esinye isinyathelo esiqhubekela phambili ezweni lobuchwepheshe.
Umlayezo Wokuya Nawe Ekhaya
- Isifo sikashukela sohlobo 1 yisimo lapho amasosha omzimba ebhubhisa khona amaseli awo akhiqiza i-insulin.
- Lesi sifo asiveli sonke ngesikhathi esisodwa; sikhula ngezigaba eziningana. Izimpawu zivela esigabeni sesithathu.
- Umuthi omusha obizwa ngokuthi i-Teplizumab (Tzield) ungalibazisa ukuqala kwezimpawu cishe iminyaka emibili kubantu abanesifo sesigaba sesi-2.
- Lesi sikhathi sinikeza isiguli "isikhathi samahhala" esibalulekile ngokwengqondo nangokomzimba.
- Uma usola ukuthi wena noma othile emndenini wakho usengozini yokuba nesifo sikashukela sohlobo 1, kubaluleke kakhulu ukukhuluma nodokotela wakho ngakho.
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