Ingabe udokotela wakho ukunike umuthi wesimo esifana nokucindezeleka noma ubuhlungu obungapheli? Uke wezwa ngegama elithi 'ama-antidepressant e-tricyclic' phakathi kwalawo mithi? Nakuba lena iyimithi yesizukulwane esidala, isasebenza kakhulu kwezinye izimo. Ngakho-ke namuhla, ake sixoxe ngakho konke ngalezi zidakamizwa zokucindezeleka ze-tricyclic, noma "ama-TCA" ngamafuphi.
Kalula nje, iyini le mithi yokucindezeleka yama-tricyclic (ama-TCA)?
Ama-antidepressant e-Tricyclic (TCA) ayiqembu lemithi esiza ukulawula izimpawu zesifo sokucindezeleka okukhulu. Nakuba enegama elithi "i-antidepressant" egameni lawo, odokotela bayawanikeza nemithi yezinye izimo ezahlukahlukene.
Lezi zibizwa nangokuthi ama-antidepressant "esizukulwaneni sokuqala" ngoba kwakuyiwona ama-antidepressant okuqala ukutholwa. Zibizwa ngokuthi "ama-tricyclic" ngoba zinezindandatho ezintathu esakhiweni sazo samakhemikhali.
Kulezi zinsuku, ngenxa yokuthi imithi emisha yokucindezeleka iphephile futhi inemiphumela emibi embalwa (njenge-SSRIs), odokotela abavami ukunikeza ama-TCA okucindezeleka. Kodwa-ke, angase asebenze kangcono kwabanye abantu abangazange baphendule kweminye imithi. Avame ukusetshenziswa nakwezinye izimo.
Yiziphi izinhlobo zama-TCA? Yiziphi izinhlobo zezifo odokotela abazinikeza zona?
Kunezinhlobo eziningana eziyinhloko zama-TCA asetshenziswa eSri Lanka nasemhlabeni jikelele. Hlola ukuthi imithi udokotela wakho ayinikezile ingenye yalezi.
| Igama Elijwayelekile | Amacala asetshenziswa njalo |
|---|---|
| I-Amitriptyline | Vimbela ukucindezeleka, ubuhlungu obungapheli, ubuhlungu bemizwa, kanye ne-migraines |
| I-Imipramine | Ukucindezeleka, ukuchama embhedeni ezinganeni ezincane |
| I-Nortriptyline | Ukucindezeleka, ubuhlungu obungapheli |
| I-Clomipramine | Isebenza kahle kakhulu kwi-Obsessive-Compulsive Disorder (OCD), isimo esibonakala ngemicabango nezenzo ezingafuneki. |
| I-Doxepin | Ukucindezeleka, ukukhathazeka, ukungakwazi ukulala |
Ngaphezu kokucindezeleka kanye ne-OCD okukhulunywe ngayo ngenhla, odokotela banikeza lo muthi kwezinye izimo eziningana. Lokhu kubizwa ngokuthi "ukusetshenziswa okungekho kulabel." Lokhu kusho ukuthi umuthi unikezwa ngesimo esingesona leso owavunyelwa ngaso, lapho ucwaningo lukhombisile ukuthi uwusizo kwesinye isimo.
- Ubuhlungu obungapheli: Ubuhlungu obuhlobene kakhulu nezinzwa, njenge-diabetesic neuropathy kanye ne-postherpetic neuralgia.
- Ukuvimbela i-migraine: Lawula i-migraine evame ukwenzeka.
- Ukungalali: Abanye abantu banikezwa imithamo ephansi ukuze babasize balale.
- Izinkinga zokukhathazeka
- I-Fibromyalgia: Ubuhlungu nokukhathala emzimbeni wonke.
- Ukuchama Embhedeni: Lesi simo ngezinye izikhathi sinconywa ezinganeni ezincane.
Lo muthi usebenza kanjani emzimbeni?
Kalula nje, ubuchopho bethu buqukethe amakhemikhali adlulisa imiyalezo phakathi kwamangqamuzana ezinzwa. Siwabiza ngokuthi ama-neurotransmitter . `I-Norepinephrine` kanye ne-`Serotonin` yizinzwa ezimbili ezibaluleke kakhulu ezilawula imizwa yethu, injabulo, kanye nokuziphatha.
La mazinga angaba phansi ezimweni ezifana nokucindezeleka. Ama-TCA asebenza ngokwandisa amazinga ala ma-neurotransmitter, i-``Norepinephrine`` kanye ne-``Serotonin`` ebuchosheni, okuthuthukisa ukuxhumana phakathi kwamangqamuzana ezinzwa.
Uma kulawulwa ubuhlungu, le mithi ivimba izimpawu zobuhlungu ezivela emgogodleni ziye ebuchosheni.
Kodwa kanye nale nqubo, amanye ama-receptor emzimbeni nawo ayavinjelwa. Yingakho kuvela imiphumela emibi njengomlomo owomile kanye nobunzima bokuchama.
Iyini imiphumela emibi kanye nezingozi zale mithi?
Ama-TCA anemiphumela emibi eminingi kancane kunemithi emisha. Kodwa-ke, akuwona wonke umuntu oyitholayo. Uma itholakala, izoncipha ngokuhamba kwesikhathi njengoba umzimba ujwayela imithi.
Imiphumela emibi evamile
- Umlomo owomile
- Ukuqunjelwa
- Isiyezi
- Ukozela
- Umbono ofiphele
Eminye imiphumela emibi
- Ubunzima bokuchama noma ukugcinwa komchamo
- Ukwanda kwesilinganiso senhliziyo (i-Tachycardia)
- Ukwehla kwengcindezi yegazi okubangelwa yi-orthostatic (umfutho wegazi ophansi lapho umi noma uvuka)
- Ukwanda kwesifiso sokudla kanye nokuzuza isisindo
Uma le miphumela emibi ikukhathaza, qiniseka ukuthi ukhuluma nodokotela wakho ngaphambi kokuyeka umuthi. Angase akwazi ukulungisa umthamo noma aphakamise esinye isisombululo.
Amacala adinga ukunakwa okukhethekile
- Uma unesifo senhliziyo: Ama-TCA angathinta ezinye izimo zenhliziyo, ngakho udokotela wakho angase afune ukwenza i-EKG ngaphambi kokuqala lo muthi.
- Uma unesifo sokuwa/sokuquleka: Lo muthi ungase wandise kancane ingozi yakho yokuquleka.
- Uma ukhulelwe noma uhlela ukukhulelwa: Ama-TCA awaphephile kakhulu ngesikhathi sokukhulelwa, ngakho-ke kubalulekile ukukhuluma nodokotela wakho ngalokhu.
Okubalulekile: Kube khona ingozi encane yokuzibulala lapho abantu abasha abangaphansi kweminyaka engu-25 beqala ukusebenzisa lo muthi. Uma wena noma ingane yakho ninemicabango enjalo, tshela udokotela wakho ngokushesha.
Ingabe kufanele ukhathazeke ngokudlula ngokweqile?
Yebo, lokhu kuyinto okufanele siyiqaphele nakanjani. Ama-TCA ayizinhlobo zemithi engabangela ubuthi obukhulu uma ithathwa ngokweqile.
Kodwa khumbula, le ngozi ayiveli uma nje uthatha isilinganiso esiqondile esinqunywe udokotela wakho. Ukweqisa izidakamizwa kwenzeka kuphela uma uthatha imithi eminingi kakhulu ngephutha, ngokungazi, noma ngamabomu.
Ngakho-ke, phuza imithi yakho njengoba nje udokotela wakho ekutshelile. Gcina amaphilisi akho endaweni ephephile kude nezingane nezilwane ezifuywayo.
Izimpawu zokudlula ngokweqile
- Ukuphazamiseka kwenhliziyo
- Umfutho wegazi ophansi kakhulu
- Ukozela okukhulu
- Ukuquleka
- Ukuthuthumela
- Isifo sokulahlekelwa yingqondo
- Isimo se-Coma
Uma wena noma othile omaziyo ehlangabezana nanoma yiziphi zalezi zimpawu, ungalibali. Shayela ngokushesha ku-1990 ukuze uthole i-ambulensi, noma uye eMnyangweni Wezimo Eziphuthumayo (ETU) wesibhedlela esiseduze. Uma kudingeka, ungashayela ne-National Poison Information Centre e-Colombo National Hospital ukuze uthole iseluleko.
Umlayezo Wokuya Nawe Ekhaya
- Ama-TCA ayiklasi elidala, kodwa eliwusizo kakhulu lemithi elapha izimo ezahlukahlukene, okuhlanganisa ukucindezeleka, ubuhlungu obungapheli, kanye ne-migraines.
- Lezi zinemiphumela emibi eminingi kancane kunemithi emisha, kodwa akuwona wonke umuntu oyitholayo. Uma unemiphumela emibi ekhathazayo, khuluma nodokotela wakho.
- Ungalokothi ushintshe umthamo wemithi noma uyeke ukuwuthatha ngokuzumayo ngaphandle kweseluleko sikadokotela wakho.
- Gcina imithi endaweni ephephile njalo lapho izingane zingayitholi khona.
- Qaphela izimpawu zokusebenzisa ngokweqile. Uma usola into enjalo, hamba uye eMnyangweni Wezimo Eziphuthumayo (ETU) wesibhedlela esiseduze ngokushesha.
- Uma unemibuzo mayelana nomuthi wakho, ukusebenza kwawo, noma imiphumela emibi, ungesabi ukubuza udokotela wakho. Ukhona ukuzokusiza.
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