Uma umuntu ethola ukufakelwa izinso okusha, kufana nokuthola impilo entsha. Kodwa ngemva kokuhlinzwa okukhulu kangaka, ngezinye izikhathi kungavela izinkinga ezingalindelekile. Isibonelo, ukutheleleka okukhulu okungase kwenzeke kumuntu oke wafakelwa izinso kubizwa ngokuthi i-BK Viral Nephritis. Lokhu kungathinta ukusebenza kwezinso lakho elisha futhi kuphazamise ngisho nempumelelo yokufakelwa. Kodwa ungakhathazeki, uma sikwazi kahle lokhu, kunezindlela zokuzivikela kulesi simo. Ngakho-ke, ake sixoxe ngalokhu ngokuningiliziwe namuhla.
Iyini le gciwane le-BK?
Kalula nje, i-BK virus nephritis iyisifo esiyingozi esibangelwa ukuvuselelwa kwe-BK polyomavirus, ebilokhu ithule (ifihliwe) emzimbeni wakho ngemva kokufakelwa izinso. Leli gciwane laqala ukutholwa ngo-1971 esigulini esifakelwe izinso esinezinhlamvu zokuqala ezithi "BK." Yingakho libizwa ngokuthi i-BK virus.
Igciwane le-BK empeleni liyisifo sokuphefumula esivame kakhulu, esivame ukungabi nazimpawu, esisakazeka ngokukhishwa okufana ne-mucus. Umuntu ophilile akazizwa ngisho nokuthi uthelelekile ngaleli gciwane. Kodwa-ke, uma igciwane selingene emzimbeni, lingahlala lilele emizimbeni yethu impilo yethu yonke, ngaphandle kokubangela izinkinga.
Ucwaningo lusikisela ukuthi abantu abangaphezu kuka-80% emhlabeni banama-antibodies alwa naleli gciwane. Lokhu kusho ukuthi cishe sonke sike savezwa yileli gciwane sisebancane. Umuntu ojwayelekile ongafakelwanga izinso ngeke alimale yileli gciwane emzimbeni wakhe.
Lokhu kungaba yingozi kanjani kumuntu oke wafakelwa izinso?
Ngemva kokufakelwa izinso, uzonikezwa imithi ekhethekile yokuvimba umzimba wakho ukuthi wenqabe izinso ezintsha. Le mithi ibizwa ngokuthi imithi yokulwa nokwenqatshwa kanye nemithi yokucindezela amasosha omzimba. Le mithi isebenza ngokwenza buthaka isimiso somzimba wakho sokuzivikela somzimba. Lokhu kuvumela izinso ezintsha ukuthi zivumelane nomzimba wakho ngaphandle kokuhlaselwa.
Kodwa uma amasosha omzimba wakho ebuthakathaka, ikhono lomzimba wakho lokulwa nezinye izifo nalo liyancipha. Ngaleso sikhathi, igciwane le-BK elalilele emzimbeni wakho "liyavuka," okusho ukuthi liphinde lisebenze.
Leli gciwane elisebenzayo lihlasela ngqo izinso zakho ezintsha. Lokhu kubangela ukuvuvukala, noma ukuvuvukala, kwezinso kanye nama-ureter. Yilokhu esikubiza ngokuthi i-nephritis .
Lokhu kuvuvukala kancane kancane kubangela ukuthi izinso zingasebenzi kahle. Uma lesi simo siba sibi kakhulu, sibizwa ngokuthi i-BK virus nephropathy.Kubizwa ngokuthi i-nephropathy. Lokhu kusho ukuthi izinso zonakele kakhulu, futhi ekugcineni zingase zehluleke ngokuphelele. Kulinganiselwa ukuthi cishe u-2% wabantu abafakelwe izinso bathola le nephropathy.
Ziyini izimpawu ze-BK Viral Nephritis?
Esikhathini esiningi, abantu abanalesi sifo ababonisi zimpawu. Kodwa-ke, uma kuvela izimpawu, kufanele uqaphele izinto ezilandelayo.
| Isibonakaliso | Incazelo |
|---|---|
| Izinguquko emchameni | Igazi emchameni noma emchameni ophenduka obomvu ngokunsundu. |
| Ubunzima bokuchama | Ubuhlungu noma ukushisa lapho uchama, ubunzima bokuchama. |
| Isinyi asiphumi ngokuphelele | Ukuzizwa sengathi kusekhona umchamo osele ngemva kokuchama. |
| Ukwanda kwesisindo ngokuzumayo | Ukwanda kwesisindo somzimba esiyikhilogremu elilodwa noma ngaphezulu esikhathini esifushane, njengamahora angu-48. |
| Ubuhlungu | Ubuhlungu noma ukuqaqamba esiswini noma esiswini esingezansi. |
Ngaphezu kwalokho, udokotela wakho angase aqaphele izinto ezifana namazinga aphezulu e-creatinine kanye namazinga e-urea nitrogen egazini lakho emibikweni yokuhlolwa kwegazi nomchamo.
Uma uhlangabezana nanoma yiziphi zalezi zimpawu, xhumana nochwepheshe wezinso ngokushesha. Iningi lalezi zifo livela ezinyangeni ezintathu zokuqala ngemva kokufakelwa izinso.Ngakho-ke udinga ukunakekela umzimba wakho kahle ngalesi sikhathi.
Yiziphi izingozi zempilo ezibangelwa yilokhu kutheleleka?
Ingozi enkulu ye-BK virus nephritis ukulimala kwezinso zakho ezintsha. Kwezinye izimo ezimbi kakhulu, ingozi yokulahlekelwa ngokuphelele kwe-graft ingaba phezulu ngo-30% kuya ku-80%.
Ngaphezu kokulimaza izinso, leli gciwane lingabangela nezinye izinkinga ezinkulu zempilo.
- Umdlavuza: Igciwane lingabangela amangqamuzana ukuba akhule ngendlela engavamile futhi akhe izimila ezinomdlavuza ezithweni zomzimba.
- I-Capillary leak syndrome: Isimo esibi esibangelwa ukuvuza kwe-plasma yegazi kusuka emithanjeni yegazi emincane kakhulu iye emisipheni ezungezile, ezithweni zomzimba, nasezicutshini.
- I-Encephalitis: Uma igciwane lisakazekela ebuchosheni, izicubu zobuchopho zingavuvukala. Lokhu kungabangela izimpawu ezifana nokushintsha kobuntu kanye nokuquleka.
- I-pneumonia: Igciwane lisakazekela emaphashini futhi libangela ubunzima bokuphefumula ngenxa yoketshezi oluwagcwalisayo.
- I-hepatitis ebangelwa yigciwane: Ukusabalala kwegciwane esibindini kungabangela ukuvuvukala kwesibindi.
Ungasithola kanjani lesi sifo ngokunembile?
Udokotela wakho uzokwenza izivivinyo eziningana ukuqinisekisa ukuthi unalesi sifo.
| Ukuhlolwa | Uhlola ini? |
|---|---|
| Ukuhlolwa kwegazi | Bahlola igazi ukuze babone izingcezu ze-DNA noma ze-mRNA zegciwane le-BK. |
| Ukuhlolwa komchamo | Umchamo uhlolwa uhlobo olukhethekile lweseli olubizwa ngokuthi "amaseli e-decoy." Lawa ngamaseli akhiwa ngamaseli ezinso athelelekile futhi akhishwa emchameni. Aphinde ahlole ukuthi kukhona yini izingcezu ze-DNA/mRNA zegciwane. |
| I-biopsy yezinso | Lena yindlela ethembeke kakhulu yokuxilonga lesi sifo. Kuthathwa izingcezu ezimbili ezincane kakhulu zezicubu ezinso bese zihlolwa. |
Ungaziphatha kanjani futhi uzivikele kanjani?
Akukho ukwelashwa okukodwa okuvunyelwe ngokuphelele kwalesi simo. Kodwa-ke, udokotela wakho uzosebenzisa izindlela ezahlukahlukene zokuphatha lesi simo.
- Ukunciphisa umthamo wemithi yokucindezela amasosha omzimba: Lena yindlela eyinhloko yokwelapha. Uma igciwane liqinisekisiwe ukuthi liyasebenza, udokotela wakho uzonquma ukunciphisa umthamo wemithi yakho.
- Imithi yokulwa namagciwane: Eminye imithi inganikezwa ukunciphisa inani legciwane emzimbeni.
- Eminye imithi: Kungadingeka ushintshe imithi yakho yokucindezela amasosha omzimba noma unikezwe ama-antibiotic okutheleleka kwesibili.
Singazivikela kanjani kulokhu?
Njengoba sonke sithola leli gciwane ngesikhathi siseyingane, asikwazi ukulawula ukungena kwalo emzimbeni. Kodwa-ke, kunezinto eziningana ongazenza ukuze unciphise ingozi yokuthola lesi simo ngemva kokufakelwa izinso. Into ebaluleke kakhulu ukuthi uhlolwe njalo njengoba kuceliwe udokotela wakho.
- Ngaphambi kokuba kuvele izimpawu, kwenziwa ukuhlolwa kwegazi nomchamo njalo ngezikhathi ezithile ukuze kuhlolwe ukuthi igciwane seliqalile yini ukusebenza.
- Ngokuvamile, kunconywa ukuhlola njalo ezinyangeni ezintathu eminyakeni emibili yokuqala ngemva kokufakelwa, bese kuba minyaka yonke iminyaka emihlanu.
- Uma lezi zivivinyo zithola igciwane, udokotela uzolungisa umthamo wemithi yokucindezela amasosha omzimba.
Okumele ukwenze nje ukunaka noma yiziphi izimpawu ezincane , uzibike kudokotela wakho ngokushesha, bese wenza ukuhlolwa akuncomayo ngesikhathi. Uma wenza lokho, uzovikeleka kulokhu kutheleleka okungathi sína futhi uzokwazi ukuhlala uphilile ngenso yakho entsha isikhathi eside.
Umlayezo Wokuya Nawe Ekhaya
- Igciwane le-BK liyigciwane elivame kakhulu elingenangozi kubantu abaphilile, kodwa lingaba yingozi kumuntu oke wafakelwa izinso.
- Ngemva kokufakelwa izinso, igciwane ebelilele emzimbeni lingase liphinde lisebenze ngenxa yemithi yokucindezela amasosha omzimba.
- Qaphela izimpawu ezifana nokushintsha komchamo, ubuhlungu lapho uchama, kanye nokukhuluphala ngokuzumayo.
- Indlela engcono kakhulu yokuzivikela kulesi simo ukuhlolwa njalo ngezikhathi ezithile njengoba kunconywe udokotela wakho.
- Uma unokungabaza noma izimpawu, ungalibali bese uthintana nodokotela wakho ukuze akunike iseluleko.
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