Mhlawumbe othile emndenini wakho unesifo sezinso. Noma mhlawumbe utholakale ukuthi une-high blood pressure ophakathi kweminyaka engama-30 noma engama-40 futhi ufuna imbangela. Namuhla sikhuluma ngesifo esihlukile kancane, kodwa esivame kakhulu, esizuzwa njengefa esithinta izinso. Lesi sifo ngokwezokwelapha sibizwa ngokuthi i-Autosomal Dominant Polycystic Kidney Disease. Njengoba lokho kukude kakhulu kithi, sizokubiza ngokuthi i-ADPKD ngamafuphi.
Kalula nje, iyini i-ADPKD?
Kalula nje, lesi sifo sibangela ukwakheka kwama-cyst amaningi agcwele uketshezi ezinso zakho. Cabanga ngezinso njengezihlungi emizimbeni yethu. Njengoba la ma-cyst ekhula, izinso azisakwazi ukusebenza kahle. Lokhu kungaholela ezinkingeni zempilo ezifana nomfutho wegazi ophakeme, izifo zomgudu womchamo, kanye namatshe ezinso. Nakuba kungebona bonke abantu abathola lesi simo, abanye abantu bangaze bafinyelele ngisho nasekuhlulekeni kwezinso.
Esinye sezici eziyingqayizivele zalesi sifo ukuthi ungase ungabi nazimpawu iminyaka eminingi noma ngabe unazo. Izimpawu zivame ukuqala ukuvela phakathi kweminyaka engama-30 nengama-40. Yingakho sibizwa nangokuthi "i-PKD yabantu abadala."
Kodwa ungakhathazeki. Nakuba kungekho ikhambi okwamanje, uma uphatha izimpawu zakho, ulandela indlela yokuphila enempilo, futhi usebenzisana nodokotela wakho, ungaphila impilo esebenzayo iminyaka eminingi.
Ziyini izimpawu ze-ADPKD?
Akuwona wonke umuntu one-ADPKD ozoba nezimpawu. Kwabanye, kungathatha iminyaka ukuthi izimpawu zivele. Ake sibheke ezinye zezimpawu ezivamile ezihambisana nalesi sifo. Ngizokuhlukanisa lokhu kube izingxenye ezimbili ukuze uqonde.
| Uhlobo oluyisici | Izinto okufanele uzibone |
|---|---|
| Izimpawu zokuqala (Izinto zokuqala kuqala) |
|
| Izimpawu ezenzeka njengoba isifo siqhubeka (Lapho izinso sezicishe zingasebenzi kahle) |
|
Kungani i-ADPKD ivela? Ingabe iwufuzo?
Yebo, lesi yisifo esizuzwa njengefa . Imbangela enkulu yalokhu ukukhubazeka kwezakhi zofuzo ezimbili ku-DNA yethu, okungukuthi `PKD1` kanye `PKD2`. Lezi zakhi zofuzo yizo ezinikeza amangqamuzana ezinso isignali yokuthi "kufanele akhule nini". Uma kukhona ukukhubazeka kwenye yalezi zakhi zofuzo, amangqamuzana ezinso akhula ngendlela engalawuleki futhi akhe lawo ma-cyst esiwashilo.
Cabanga ngakho, ezifweni eziningi ezizuzwe njengefa, udinga ukuthola isakhi sofuzo esinephutha kumama wakho nakubaba wakho. Kodwa ku-ADPKD, udinga ukuthola isakhi sofuzo esinephutha kumzali oyedwa kuphela . Yingakho sibizwa ngokuthi "i-autosomal dominant."
Lokhu kusho ukuthi uma omunye wabazali bakho enalesi sifo, unethuba elingu-50% lokusithola . Kodwa-ke, akuvamile kakhulu, lesi sifo singavela ngenxa yoshintsho olungahleliwe ku-gene yomuntu, ngaphandle kokuba bobabili abazali babe nalesi sifo.
Uthola kanjani ukuthi unalesi sifo?
Uma udokotela wakho esola inkinga yezinso ngokusekelwe ezimpawini zakho, angakudlulisela kuchwepheshe wezinso (udokotela wezinzwa). Udokotela uzokubuza imibuzo efana nale:
- Ziyini izimpawu zakho futhi zaqala nini?
- Uyawazi umfutho wegazi lakho?
- Ingabe kukhona ubuhlungu noma kuphi? Uma kunjalo, kuphi?
- Wake waba namatshe ezinso ngaphambili?
- Ingabe ukhona emndenini onesifo sezinso?
Udokotela uzokhipha izivivinyo eziningana ukuze ahlole izinso zakho.
- I-Ultrasound Scan: Lokhu kusebenzisa amaza omsindo ukuthatha izithombe zangaphakathi lomzimba. Lokhu kuvame ukuba ukuhlolwa kokuqala okwenziwayo.
- I-MRI scan: I-scan enamandla esebenzisa omaginethi namagagasi omsakazo ukuthola izimila ezincane kakhulu ukuthi zingabonwa nge-ultrasound.
- I-CT Scan: Enye indlela enamandla yokuskena esebenzisa ama-X-ray ukuthola izithombe ezinemininingwane yomzimba.
Ngaphezu kwalokho, i-DNA yakho ingahlolwa ukuze kubonakale ukuthi unayo yini i-gene enesici `PKD1` noma `PKD2`. Kodwa-ke, nakuba lokhu kuhlolwa kwezakhi zofuzo kungabonisa ukuthi unayo yini i-gene enesici, akukwazi ukubikezela ukuthi lesi sifo sizoqala nini noma ukuthi sizoba sibi kangakanani .
Ukwelashwa nezinto ongazenza ekhaya
Akukho ukwelashwa kwe-ADPKD okwamanje. Kodwa kunezinto eziningi esingazenza ukuze siphathe izinkinga zempilo ezibangelwa yilesi sifo futhi sivimbele ukwehluleka kwezinso.
Ukwelashwa kwezokwelapha
- Imithi yokunciphisa ukwehluleka kwezinso: Kubantu abadala abasengozini yokuqhubeka ngokushesha kwalesi sifo, imithi efana ne-`Tolvaptan (Jynarque)` inikezwa ukunciphisa ukwehla kokusebenza kwezinso.
- Imithi elawula umfutho wegazi ophakeme.
- Ama-antibiotic okutheleleka komgudu womchamo.
- Izibulali-zinhlungu.
Uma izinso zakho zehluleka ukusebenza, kungadingeka ukuthi welashwe nge- dialysis . Lokhu kuhilela ukusebenzisa umshini ukuhlunga igazi lakho, ukususa udoti, usawoti, namanzi angaphezulu emzimbeni wakho. Enye indlela ukufakelwa izinso. Khuluma nodokotela wakho ngalokhu ukuze ufunde kabanzi.
Izinto ongazenza ekhaya
Ukuze uvikele izinso zakho futhi uzigcine zisebenza kahle isikhathi eside ngangokunokwenzeka, kubalulekile ukuhlala uphilile ngangokunokwenzeka.
- Ukudla okufanele: Yidla ukudla okunempilo okunosawoti omncane. Usawoti ungakhuphula umfutho wegazi.
- Hlala umatasa: Ukuzivocavoca kungasiza ekulawuleni isisindo kanye nomfutho wegazi, kodwa gwema imidlalo yokuthintana, engalimaza izinso zakho.
- Gwema ukubhema: Ukubhema konakalisa imithambo yegazi ezinso futhi kungandisa nengozi yokwakheka kwama-cyst.
- Phuza amanzi amaningi: Ukuphelelwa amanzi emzimbeni nakho kungabangela ukwakheka kwama-cysts kaningi.
Ezinye izinkinga ezingase zenzeke ngenxa ye-ADPKD
I-ADPKD ingandisa nengozi yezinye izinkinga zempilo, futhi kubalulekile ukuzazi lezi futhi.
| Ezinye izinkinga zempilo ezingaba khona (Izinkinga Ezingaba Khona) | |
|---|---|
| I-Aneurysm (ubuthakathaka nokuvuvukala kodonga lomthambo wegazi ebuchosheni) | Ukwakheka kwama-cysts esibindini kanye nakuma-pancreas |
| I-Diverticulosis (izikhwama ezincane emathunjini amakhulu) | Ama-Hernia |
| Izifo ze-valve yenhliziyo (isib. i-Mitral valve prolapse, i-Aortic regurgitation) | Ukulahlekelwa ukusebenza kwezinso |
| Umfutho wegazi ophezulu ngesikhathi sokukhulelwa (i-Preeclampsia) | Ubuhlungu obuqhubekayo |
Izinga lokuqhubeka kwesifo lincike ekutheni unesici ku-gene ye-`PKD1` noma ye-`PKD2`. Ngokuvamile, abantu abanesici ku-gene ye-`PKD1` basengozini yokuthola ukwehluleka kwezinso ngokushesha kunalabo abanesici se-`PKD2`. Ngakho-ke kungcono ukukhuluma nodokotela wakho ukuze uthole ukuthi isimo sakho siyini ngempela.
Umlayezo Wokuya Nawe Ekhaya
- I-ADPKD yisifo esizuzwe njengefa esibangela ukwakheka kwama-cyst agcwele uketshezi ezinso.
- Umfutho wegazi ophakeme, obonakala ngeminyaka yama-30 nama-40, ungase ube uphawu olukhulu lokuqala lwalesi sifo.
- Uma omunye umzali enalesi sifo, ingane inethuba elingu-50% lokusithola.
- Nakuba kungekho ikhambi eliphelele lalokhu, ungazivikela izinso zakho ngokulawula umfutho wegazi lakho nangokulandela indlela yokuphila enempilo .
- Uma unokungabaza noma izimpawu ngalokhu, ungesabi futhi uxhumane nodokotela wakho ukuze akunike iseluleko.
💬 Comments (0)
Awekho amazwana athunyelwe okwamanje. Faka amazwana akho lapha okokuqala ngqa.
Engeza amazwana akho