Wake wazibuza ukuthi imizimba yethu iwathola kanjani amandla ewadingayo uma singadli isikhashana, noma uma sizivocavoca kanzima? Njengoba nje sigcina ibhange lamandla efonini yethu ukuze silisebenzise lapho ibhethri liphela, imizimba yethu nayo inomthombo wamandla esingawasebenzisa ezimweni eziphuthumayo. Yilokho esikubiza ngokuthi i-glycogen ngokwezokwelapha. Lena yingxenye ebaluleke kakhulu yokuphathwa kwamandla emizimba yethu.
Kuyini i-glycogen, ngokuhumusha okulula?
Kalula nje, i-glycogen uhlobo lwe -glucose egcinwe emizimbeni yethu. Manje ungase uzibuze ukuthi iyini i-glucose. I-glucose uhlobo lukashukela . Umzimba wethu uthola i-glucose ekudleni esikudlayo, ikakhulukazi ukudla okuqukethe ama-carbohydrate ( isitashi ) (njengelayisi, isinkwa, amazambane). Le glucose inguphethiloli oyinhloko ohlinzeka ngamandla kumaseli emizimbeni yethu.
Cabanga nje, ngemva kokudla, igazi lethu liqukethe ushukela omningi kunalokho elikudingayo. Ngakho-ke umzimba wenzani? Uthatha lo shukela omningi bese uwugcina ephaketheni elingasetshenziswa kamuva. Lelo phakethe elikhulu, elenziwe ngama-molecule eglucose ayizinkulungwane ahlanganiswe ndawonye, libizwa ngokuthi i-glycogen.
Le nqubo yenzeka ngezindlela ezimbili:
1. I-Glycogenesis: Inqubo yokuthatha i-glucose eningi egazini bese uyigcina njenge-glycogen.
2. I-Glycogenolysis : Uma umzimba wethu udinga amandla, uyaphula i-glycogen egciniwe, uyiguqule ibe yi-glucose, bese uyikhipha egazini.
Kungenxa yokuthi lezi zinqubo ezimbili zenzeka ngqo ukuthi umzimba wethu uthola amandla uma uwadinga futhi uvikelekile ekwandeni okungadingekile kwamazinga kashukela egazini.
Ikuphi le ndawo yokugcina amandla?
I-Glycogen igcinwa ikakhulukazi emisipheni yesibindi kanye nemisipha yamathambo , kanti inani elincane ligcinwa ebuchosheni nakwezinye izicubu.
Cabanga ngale ndlela, isibindi singagcina iphesenti eliphezulu le-glycogen uma kuqhathaniswa nobukhulu baso. Kodwa ngenxa yokuthi sinenqwaba yemisipha emizimbeni yethu, iningi (cishe izingxenye ezintathu kwezine) le-glycogen iyonke ligcinwa emisipheni.
Inani le-glycogen eligcinwe emzimbeni wakho lincike ezintweni eziningana:
- Inani lama-carbohydrate owadlayo.
- Uzivocavoca kangakanani futhi unamandla kangakanani.
- Igebe lesikhathi phakathi kokudla.
- Umsebenzi we-enzyme yesibindi.
Le nqubo yokugcina, ebizwa ngokuthi i-glycogenesis, ilawulwa yi-hormone ebizwa ngokuthi i-insulin . Uma sidla, amazinga ethu kashukela egazini ayakhuphuka. Ama-pancreas ethu abe esekhiqiza i-insulin, etshela amangqamuzana ethu ukuthi agcine ushukela omningi njenge-glycogen.
I-Glycogen, i-glucose, ne-glucagon - uyini umehluko phakathi kwalezi zinto ezintathu?
Nakuba la magama amathathu ezwakala efana, imisebenzi yawo ihlukile. Ukuze uqonde kahle lo mehluko, bheka ithebula elingezansi.
| Igama | Yini leyo? | Kuphi? |
|---|---|---|
| I-glucose | Uphethiloli oyinhloko wamaseli omzimba. I-molecule kashukela elula kakhulu. | Ikakhulukazi egazini (egazini). |
| I-Glycogen | Indlela izinkulungwane zama-molecule e-glucose ezihlanganiswa futhi zigcinwe ngayo. (Ukugcinwa kwamandla) | Ikakhulukazi esibindini nasemisipheni. |
| I-Glucagon | I-hormone ekhombisa ukuwohloka kwe-glycogen ukuze ikhiqize ushukela uma amazinga kashukela egazini ephansi. | Kukhiqizwa yi-pancreas bese kukhishwa egazini. |
Kalula nje, i-glucose ifana nemali oyisebenzisayo. I-Glycogen ifana nemali onayo ebhange. I-Glucagon ifana 'nomyalezo' okutshela ukuthi ushayele ibhange uma udinga imali.
Kunomehluko omncane endleleni i-glycogen ehlukaniswa ngayo esibindini nasemisipheni. Isibindi sihlukanisa i-glycogen ukuze senze i-glucose ukuze wonke umzimba uyisebenzise. Kodwa i-glucose eyenziwa yi-glycogen yemisipha ingasetshenziswa kuphela yilawo misipha . Isizathu salokhu ukuthi imisipha idinga amandla amaningi ngesikhathi sokuzivocavoca. Uma idonsa i-glucose egazini kuwo wonke umzimba, izitho ezibalulekile njengobuchopho ngeke zibe ne-glucose eyanele. Ngakho-ke imisipha igcina izitolo zayo zamandla.
Ngingakwazi yini ukuhlola amazinga ami e-glycogen?
Eqinisweni, ukulinganisa amazinga e-glycogen ngqo kuyinkimbinkimbi kancane futhi akuyona into evame ukwenziwa. Ngoba leli zinga lishintsha njalo phakathi nosuku kuye ngokuthi sidlani futhi siphuzani nokuthi sivivinya umzimba kangakanani. Ezimweni ezikhethekile, uma kudingeka, udokotela angathatha ingxenye encane yezicubu esibindini noma emisipheni ayihlole (lokhu kubizwa ngokuthi i- biopsy ) ukuze ahlole amazinga e-glycogen.
Kodwa ngokuvamile, odokotela benza izivivinyo ezilula ukuze babone ukuthi kukhona yini inkinga ehlobene ne-glucose.
- Ukuhlolwa kwegazi ukuhlola amazinga kashukela egazini kanye nokusebenza kwesibindi nemisipha.
- Ukuhlolwa kwesibindi nge-ultrasound ukuze kuhlolwe ukuthi asikho yini isibindi esikhulile.
- Ukuhlolwa kwezakhi zofuzo kwenziwa uma kukhona ukusolakala kwesifo esizuzwe njengefa.
Ngokwesilinganiso, umuntu omdala onempilo unamagremu angu-600 e-glycogen agcinwe emzimbeni wakhe. Lokhu kungahluka kuye ngobukhulu bomzimba womuntu, ukudla, kanye nezinga lokuzivocavoca.
Izifo ezihlobene ne-Glycogen
Isifo Sokugcina I-Glycogen (GSD) yisimo esingavamile, esizuzwe njengefa esiphazamisa ikhono lokukhiqiza noma lokuphula i-glycogen. Sibangelwa yiphutha lofuzo. Kwenzeka lapho umzimba untula ama-enzyme adingekayo ukuze kugaywe i-glycogen.
Lokhu kungaholela emazingeni aphezulu kakhulu e-glycogen ezithweni ezifana nesibindi, noma kwabanye abantu, umzimba awukwazi ukwenza i-glycogen nhlobo. Lokhu kungaholela ezimpawini ezahlukahlukene, njengobuthakathaka bemisipha.
Nakuba kungekho ukwelashwa kwe-GSD, ukwelashwa kungalawula izimpawu. Kukhona ukwelashwa kokufaka esikhundleni sama-enzyme kwezinye izinhlobo kanye nokwelashwa kwe-cornstarch kwezinhlobo eziningi.
Uma unenkinga ngamazinga kashukela egazini lakho, ukuntuleka kwamandla, noma ukuqaqamba kwemisipha njalo, qiniseka ukuthi ukhuluma nodokotela wakho ngakho.Khuluma nodokotela wakho. Kubaluleke kakhulu ukuthola iseluleko sezokwelapha esinembile kunokufuna ulwazi ku-inthanethi.
Umlayezo Wokuya Nawe Ekhaya
- I-Glycogen yindlela imizimba yethu egcina ngayo i-glucose (ushukela). Kufana 'nebhange lamandla' emizimbeni yethu.
- La mandla agcinwa kakhulu esibindini nasemisipheni.
- I-Glycogen ibalulekile ekugcineni amazinga kashukela egazini ezinzile kanye nokunikeza amandla ngesikhathi sokuzivocavoca nokuzila ukudla.
- I-hormone i-insulin isiza ukugcina i-glucose, kanti i-hormone i-glucagon isiza ukusebenzisa amandla agciniwe kabusha.
- Uma unenkinga mayelana namazinga kashukela egazini lakho noma amandla omzimba wakho, ungaqageli ngakho futhi nakanjani thintana nodokotela wakho ukuze akunike iseluleko.
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