So wo ba no nyin ntɛmntɛm dodo? Momma yensua abrannaa ho ade!

Ɛtɔ da a, yɛn mma nyin ntɛmntɛm paa, ɛnte saa? Nanso ɛnyɛ nea ɛfata sɛ mpofirim ara benyin atenten kɛse asen mmofra afoforo, na wɔn akwaa akɛse ayɛ kɛse. Ebia eyi fi tebea bi a ɛntaa nsi koraa. Ɛnnɛ yɛrebɛka tebea a ɛte saa ho asɛm, a ɛyɛ ‘Gigantism’.

Dɛn ne ‘Abɔnefo’?

Sɛ yɛbɛka no tiawa a, gigantism yɛ tebea a ɛntaa nsi a abofra anaa aberante bi yɛ onyin hormone (GH) pii dodo . Eyi nti na mmofra yi nyin tenten sen afoforo koraa no. Mpɛn pii no, ntini ketewaa bi a ne kɛse te sɛ pea a ɛwɔ yɛn amemene no ase na ɛyɛ saa onyin hormone (GH) yi. Wɔfrɛ no pituitary gland. Nanso, sɛ akisikuru ketewaa bi ba wɔ saa pituitary gland yi mu a, ebetumi ayɛ onyin hormone (GH) pii asen nea ehia. Ɛno ne bere a gigantism ba.

Pituitary Gland yɛ ntini ketewaa bi a ɛwɔ amemene no ase, wɔ Hypothalamus ase. Ɛma nkwaadɔm bɛyɛ 8 fi adi ankasa. Growth Hormone (GH) yɛ emu biako.

Onyin Hormone a wɔsan frɛ no Human Growth Hormone (hGH) ho hia ma mmofra nyin. Ɛka nipadua no afã horow pii na ɛboa abofra no ma onyin yiye. Nanso, onyin mprɛte ahorow bi wɔ yɛn nnompe mu a wɔfrɛ no Epiphyses/Growth Plates, na sɛ wɔto mu koraa (i.e. wɔ mmerantebere ne mmabaabere akyi) a, onyin hormone (GH) mma ne tenten nkɔ soro. Nea ɛyɛ ne sɛ ɛma nnompe, ntini, ne akwaa afoforo nhyehyɛe ne ne nipadua mu nneɛma kɔ so yɛ adwuma. Saa onyin hormone (GH) yi ne hormone bi a wɔfrɛ no Insulin-like Growth Factor 1 (IGF1) a yɛn mmerɛbo na ɛyɛ no wɔ abusuabɔ kɛse. Sɛ wɔka abien yi bom a, ɛboa ma onyin ne nipadua mu nneɛma a ɛsakra.

Gigantism yɛ tebea a nipadua no yɛ onyin hormone (GH) pii dodo, na ɛma ntini, nnompe, ne ntini a ɛka bom no nyin ntɛmntɛm. Eyi ma nipadua no tenten a ɛnteɛ na nsakrae pii ba nipadua no mu ntini a ɛyɛ mmerɛw no mu. Sɛ wɔansa wɔn yare a, nnipa binom a wɔwɔ gigantism no betumi anyin abɛyɛ wɔn tenten boro anammɔn 8.

Enti, ɛho hia yiye sɛ wohu yare no na wofi ase sa yare ntɛm ara wɔ tebea horow a ɛyɛ gigantism mu.

Nsonsonoe bɛn na ɛda ‘Gigantism’ ne ‘Acromegaly’ ntam?

Gigantism ne acromegaly nyinaa yɛ tebea horow a onyin hormone (GH) a ɛboro so na ɛde ba. Nsonsonoe no wɔ nea onya nkɔso no mu. Acromegaly ba mpanyimfo mu. Gigantism nya nkɔso wɔ mmofra ne mmerante ne mmabaa a wɔadu mpanyin afe so a wɔda so ara nyin, kyerɛ sɛ, wɔn a wonnya nnuu wɔn mpanyin afe so no mu.

Sɛ yɛbɛka no tiawa a, gigantism ba bere a onyin hormone (GH) dodow kɔ soro ansa na mmofra nnompe mu nyin mprɛte no atoto (i.e., ansa na mmofra nnompe aba awiei).

Sɛ wo nyinsɛn hormone (GH) dodow kɔ soro bere a wo nyin mprɛte no atoto akyi a, ebetumi ama woanya acromegaly. Worennyin, nanso GH a ɛboro so no betumi aka wo nnompe no nsusuwii, w’akwaa kɛse, ne akwahosan tebea afoforo.

Gigantism yɛ tebea a ɛntaa nsi koraa sen acromegaly.

Hena na onya gigantism? Ɛtaa ba dɛn?

Ɛwom sɛ eyi yɛ tebea a ɛntaa nsi koraa de, nanso gigantism betumi aba abofra biara a ne nyin mprɛte nnya ntoo mu (i.e., wonnya nwiee ne babunbere) mu. Ɛtaa ba mmarimaa so sen mmeawa.

Gigantism yɛ tebea a ɛntaa nsi koraa, yiye ankasa. Sɛ nhwɛso no, ɛde besi nnɛ no, nnipa bɛyɛ 100 pɛ na wɔabɔ amanneɛ wɔ United States. Enti wubetumi asusuw sɛnea ɛho yɛ na no ho.

Ɔkwan bɛn so na mmofra nyin sɛnea ɛsɛ? Nsonsonoe bɛn na ɛwɔ gigantism mu?

Onyin hormone (GH) ne nea ɛhwɛ onyin so wɔ mmofraase. Ɛne sɛ, ɛhwɛ nipadua mu nneɛma a ɛsakra so bere a ɛma nnompe, ntini, ne ntini ahorow nyin a wotumi susuw no. Mpɛn pii no, onyin yɛ ade a egyina pintinn koraa kosi sɛ abofra bedu ne mpanyin afe so.

Wɔ mmerantebere ne mmabaabere mu no, nna mu nkwaadɔm (estrogen ne testosterone) a wɔde fi nipadua mu no kɔ soro kɛse. Eyi ma epiphyses (mprɛte a ɛma onyin) a ɛwɔ abofra nnompe atenten ano no to mu nkakrankakra. Sɛ epiphyses no to mu koraa, kyerɛ sɛ, sɛ mmabunbere wie a, ne tenten nyin gyae.

Sɛnea abofra nyin ntɛmntɛm ne nea ne tenten a etwa to bɛyɛ bere a wadu ne mpanyin afe so no gyina awosu mu nkwaadɔm pii a wonya fi wɔn awofo hɔ, nneɛma a atwa wɔn ho ahyia, ne wɔn bɔbeasu a wɔaka abom so.

Wɔ gigantism fam no, abofra no nyin ntɛmntɛm yiye, na ɔware sen mmofra afoforo a wɔn mfe ne wɔn bɔbeasu yɛ pɛ koraa. Nanso, mfiase no, kɛseyɛ ho sɛnkyerɛnne betumi ayɛ te sɛ mmofraberem onyin a ɛyɛ daa, na ɛma ɛyɛ den ma awofo sɛ wobehu.

Sɛ wowɔ nsɛmmisa anaa adwenem naayɛ bi wɔ sɛnea wo ba no nyin ho a, hwɛ hu sɛ wo ne ne duruyɛfo bɛkasa.

Dɛn ne sɛnkyerɛnne ahorow a ɛkyerɛ sɛ obi ayɛ kɛse?

Gigantism fi onyin hormone (GH) a ɛboro so. Afei nso, akisikuru a ɛwɔ pituitary gland no mu betumi de nhyɛso aba amemene ne ntini a ɛbɛn hɔ no so, na ɛde sɛnkyerɛnne ahorow bi aba. Gigantism ho sɛnkyerɛnne titiriw ne sɛ obi nyin dodo.Mmofra a wɔwɔ gigantism nyin ntɛmntɛm yiye wɔ wɔn tenten mu.

Wɔ sɛnea obi tenten/ɛsõ kɛse sen ne mfe akyi no, nipadua mu su ahorow a wohu wɔ gigantism mu no bi ne:

• Moma so a ɛda nsow yiye ne anom a ɛda nsow.
• Ntrɛwmu a ɛwɔ sẽ ntam.
• Anim afã horow a ɛyɛ den.
• Nsa ne anan akɛse, ne nsateaa a ɛyɛ den.

Nsɛnkyerɛnne afoforo a wobetumi ahu ne:

• Akwaa a ɛwɔ nipadua no mu a ɛtrɛw, titiriw abofra no koma.
• Fifiri a ɛboro so (hyperhidrosis).
• Anisoadehu mmɔho abien anaasɛ ɛyɛ den sɛ wubehu ade wɔ akyirikyiri.
• Tipaeɛ.
• Nkwaa mu yaw.
• Mmabunbere a ɛkyɛ.
• Brayɛ a ɛnkɔ so daa.
• Sɛ nhwɛso no, nna ho haw ahorow, nna mu ahomegye.
• Ntini mu mmerɛwyɛ.

Sɛ wo ba no wɔ saa sɛnkyerɛnne ahorow yi a, ɛho hia paa sɛ wo ne oduruyɛfo kasa ntɛm ara sɛnea wubetumi.

Dɛn ne nneɛma a ɛde abrannaa ba?

Mpɛn pii no, akisikuru a ɛnyɛ hu (pituitary adenoma) a ɛwɔ abofra no pituitary gland mu na ɛde gigantism ba. Eyi ma onyin hormone (GH) fi nipadua no mu dodo. Sɛ wohu sɛ mmofra a wɔwɔ gigantism a, ɛkame ayɛ sɛ bere nyinaa na wɔwɔ pituitary adenoma kɛse (akisikuru a ne kɛse yɛ mm 10 anaa nea ɛboro saa), a wɔfrɛ no macroadenoma. Gigantism nso betumi afi pituitary gland a ɛtrɛw, a wɔfrɛ no pituitary hyperplasia no mu aba.

Mmofra pii a wɔwɔ gigantism no wɔ awosu mu nsakrae bi a ɛde pituitary tumor ba. Awosu mu nsakrae a ɛtaa ba a ɛbata gigantism ho ne nkwaadɔm mu nsakrae anaasɛ wɔpopa wɔ AIP awosu mu nkwaadɔm no mu. Eyi ka nnipa a wɔwɔ gigantism bɛyɛ 29%.

Gigantism nso betumi aba sɛ awosu mu nyarewa dodow bi a ɛntaa nsi koraa a ɛma asiane a ɛwɔ hɔ sɛ obi benya pituitary tumor a ɛma onyin hormone (GH) fi mu no yɛ kɛse no fã. Saa ɔhaw ahorow yi bi ne:

• Carney complex: Eyi yɛ awosu mu tebea a ɛka honam ani kɔla na ɛde akisikuru a ɛnyɛ hu ba honam ani, koma, ne endocrine nhyehyɛe no mu. Nnipa a wɔwɔ Carney complex no mu bɛyɛ 10% kosi 13% nya pituitary adenomas a ɛma onyin hormone (GH) fi mu ba, na ɛtaa nyin nkakrankakra.
• McCune-Albright yare no:Eyi yɛ awosu mu tebea a ɛka nnompe, honam ani, ne endocrine nhyehyɛe. Ɛma café-au-lait nsensanee ba honam ani, akuru a ɛwɔ nnompe no mu, ne mmerantebere ne mmabaabere a ɛba ntɛm. Nnipa a wɔwɔ McCune-Albright syndrome no mu 20% kosi 30% wɔ onyin hormone (GH) a ɛboro so. Mpɛn pii no, eyi fi pituitary gland a ɛtrɛw (hyperplasia), anaasɛ pituitary adenoma.
• Multiple Endocrine Neoplasias (MEN) ahorow 1 anaa 4: Eyinom yɛ awosu mu tebea horow. Sɛ ɛba saa a, wo ntini a ɛma mogya tu no mu biako anaa nea ɛboro saa yɛ adwuma boro so, anaasɛ akisikuru bi ba. Eyi betumi ayɛ pituitary tumor a ɛma onyin hormone (GH) fi mu ba.
• Neurofibromatosis: Eyi yɛ awosu mu tebea bi a wɔfrɛ no neurocutaneous disorders. Eyinom ka honam ani ne ntini ahorow. Nkwammoaa nyin a ɛkɔ soro wɔ ɔkwan a ɛnteɛ so na ɛde tebea horow yi ba. Eyi betumi ama akisikuru ayɛ nipadua no nyinaa. Eyinom betumi ayɛ akisikuru a ɛma onyin hormone (GH) fi mu ba.
• Familial Isolated Pituitary Adenomas (FIPA): Eyi yɛ tebea a wonya fi awo mu. Ɛfa pituitary adenomas a ɛba ho. Ebia eyinom bi ne adenomas a ɛma onyin hormone (GH) fi nipadua no mu.

Ɔkwan bɛn so na wohu sɛ ɔwɔ gigantism?

Gigantism betumi ayɛ den kakra sɛ wobehu efisɛ ɛyɛ tebea a ɛntaa nsi koraa, ne esiane sɛ mmofra nyin betumi ayɛ soronko kɛse esiane awosu ne nneɛma a atwa yɛn ho ahyia nti.

Mpɛn pii no, nnuruyɛfo susuw sɛ ɔyɛ kɛse bere a abofra tenten boro ne tenten a wɔkyekyem pɛpɛɛpɛ no mprɛnsa wɔ ne bɔbeasu ne ne mfe ho, anaasɛ ɛboro ne tenten a wɔkyekyem pɛpɛɛpɛ a wobu akontaa fi abofra no awofo tenten so no.

Sɛ wo ba no duruyɛfo susuw sɛ wo ba no wɔ gigantism a, ɛda adi sɛ ɔde wo bɛkɔ endocrinologist (oduruyɛfo a ne ho akokwaw wɔ nyarewa a ɛfa hormone ho) nkyɛn. Oduruyɛfo no begyina wo ba no aduruyɛ ho abakɔsɛm, abusua aduruyɛ ho abakɔsɛm, nipadua mu nhwehwɛmu a edi mũ, ne nhwehwɛmu titiriw te sɛ mogya mu nhwehwɛmu ne mfoniniyɛ mu nhwehwɛmu so ayɛ nhwehwɛmu.

Sɔhwɛ ahorow bɛn na wɔde hu sɛ obi ayɛ kɛse?

Sɛ wo ba no duruyɛfo susuw sɛ ɔwɔ gigantism a, wobetumi ayɛ nhwehwɛmu ahorow a edidi so yi de akyerɛ sɛ ɔyare no wɔ hɔ:

• Growth Hormone and IGF-1 (Insulin-like Growth Factor 1) blood tests: These tests measure the levels of various hormones in a blood sample taken from the child's vein. Sɛ dodow no kɔ soro sen sɛnea ɛte daa a, ebetumi ayɛ kɛseyɛ ho sɛnkyerɛnne.
• Glucose Tolerance Test: Saa sɔhwɛ yi kyerɛ sɛnea abofra nyin mu ahoɔdennuru dodow yɛ adwuma yiye wɔ glucose ho. Wɔ sɔhwɛ yi mu no, oduruyɛfo bi gye mogya fi ntini bi mu wɔ bere ahorow mu bere a abofra no anom glucose (asikre) aduru bi awie no.
• Mfoniniyɛ mu nhwehwɛmu: Sɛ mogya mu nhwehwɛmu kyerɛ sɛ wo ba no wɔ gigantism a, mpɛn pii no wo duruyɛfo bɛkamfo akyerɛ sɛ wɔnyɛ MRI (Magnetic Resonance Imaging) anaa CT (Computed Tomography) scan. Eyinom tumi hu pituitary tumor no kɛse ne beae a ɛwɔ pefee. Wobetumi nso aboa ma wɔahu ayaresa pɔtee a ehia.

Sɛ wohu sɛ wo ba no wɔ gigantism a, oduruyɛfo no betumi ayɛ nhwehwɛmu foforo bi de ahwɛ sɛ ebia tebea no aka nipadua no afã afoforo anaa. Ebia sɔhwɛ ahorow yi bi ne:

• Echocardiogram a wɔde hwɛ sɛ komayare bi wɔ hɔ anaa.
• Dae ho adesua sɔhwɛ ahorow a wɔde hwɛ sɛ ebia wowɔ nna mu ahomegye a ɛyɛ den anaa.
• X-ray anaa DEXA/DXA scan a wɔde bɛhwɛ sɛnea wo nnompe no te.

Ɔkwan bɛn so na wɔsa gigantism?

Botae atitiriw a ɛwɔ gigantism ayaresa mu ne:

• ‘Onyin hormone’ (GH) ne ‘insulin-like growth factor 1’ (IGF1) dodow a wɔhwɛ so dwoodwoo.
• ‘Pituitary tumor’ nyin a wɔhwɛ so.
• Nkɛntɛnso a pituitary tumor nya wɔ amemene no mu ntini a ɛbɛn ne aniwa ntini no so a wɔbɛtew so.
• Nkɛntɛnso a onyin hormone (GH) nya wɔ nipadua nhyehyɛe afoforo so no a wɔbɛsa anaasɛ wɔbɛtew so.

Nnuruyɛfo taa de ayaresa ahorow a wɔaka abom di dwuma ma gigantism , a oprehyɛn ne mframa a wɔde sa yare ne ayaresa titiriw.

Ɛwom sɛ nnuru a etu mpɔn wɔ hɔ a wɔde sa onyin hormone (GH) a ɛboro so wɔ mpanyimfo mu (acromegaly) de, nanso wonnya nyɛɛ nkɛntɛnso a nnuru yi nya wɔ mmofra so no ho nhwehwɛmu yiye.

Oprehyɛn a wɔyɛ ma Gigantism

Oprehyɛn ne aduru a wɔtaa de sa gigantism. Botae no ne sɛ wobeyi pituitary tumor no afi hɔ anaasɛ wɔbɛtew ne kɛse so. Esiane sɛ pituitary akisikuru a ɛde gigantism ba no taa yɛ kɛse nti, ebia ɛho behia sɛ wɔyɛ abofra no oprehyɛn mpɛn pii na ama watumi adi onyin hormone (GH) dodow so yiye.

Ebia oduruyɛfo a ɔyɛ wo ba no de oprehyɛn bi a wɔfrɛ no transsphenoidal surgery bedi dwuma de ayi pituitary akisikuru bi afi hɔ. Eyi hwehwɛ sɛ wofa wo ba no hwene mu na wofa sphenoid sinus (tokuru bi a ɛwɔ ti nhwi mu wɔ hwene akyi, amemene no ase) mu.

Mframa a Wɔde Yɛ Ayaresa a Wɔde Ma Gigantism

Sɛ oprehyɛn no antumi antew onyin hormone dodow so a, mframa a wɔde sa yare betumi aboa. Nea ɛka eyi ho ne sɛ wɔde nnwinnade titiriw bi bedi dwuma de mframa a ano yɛ den akɔ akisikuru no so. Saa ayaresa yi yɛ adwuma nkakrankakra. Ebia ebehia sɛ wɔyɛ no mpɛn pii, na wɔde bere tenten ahomegye wɔ ntam. Ebetumi agye mfe pii nso ansa na woahu nea efi mu ba no nyinaa.

Dɛn ne nsɛnnennen a ɛwɔ ayaresa mu?

Esiane oprehyɛn ne/anaasɛ mframa a wɔde sa yare nti, nnipa a wɔwɔ gigantism no mu bɛyɛ 60% nya tebea bi a wɔfrɛ no hypopituitarism wɔ ayaresa akyi. Eyi ne bere a hormone ahorow a pituitary gland no yɛ no biako, dodow bi, anaa ne nyinaa nyɛ adwuma yiye. Wɔde nnuru a wɔde si hormone ananmu na ɛsa hypopituitarism.

Nsɛnnennen a ebetumi aba wɔ oprehyɛn a wɔyɛ de yi pituitary tumor bi mu no bi ne:

• Mogya a ɛretu.
• Amemene mu Nsu (CSF) a ɛtwetwe.
• Meningitis (amemene mu atiridiinini).
• Sodium (nkyene) ne nsu a ɛkari pɛ wɔ nipadua no mu a ɛyera.

Ebia nneɛma bɔne a efi mframa a wɔde sa yare mu ba no bi ne:

• Awo a Ɛsɛe.
• Anisoadehu a ɛyera ne amemene a ɛsɛe (ɛho yɛ na).
• Tumor a ɛba mfe pii wɔ ayaresa akyi (ɛho yɛ na).

So wobetumi asiw akɛsesɛm ano? Dɛn ne nkɔmhyɛ no?

Nea ɛyɛ awerɛhow no, biribiara nni hɔ a wubetumi ayɛ de asiw akɛsesɛm ano. Nanso, ntɛm a wobehu no ho hia yiye. Ayaresa a wodi ntɛm betumi aboa ma woasiw nsakrae a ɛma wo ba no tenten dodo no ano anaasɛ wɔdan no.

Nkɔmhyɛ a ɛbɛba mmofra ne mmerante ne mmabaa a wɔahu sɛ wɔwɔ gigantism ho no gyina nneɛma pii so:

• Sɛnea wohuu yare no ntɛm anaa akyiri yi.
• Ayaresa ahorow a wɔde hwɛ onyin mu ahoɔdennuru dodow so no tu mpɔn dɛn?
• Sɛ́ ebia nsɛnnennen bi wɔ hɔ a ɛfa gigantism ho anaa.

Mpɛn pii no, wɔn a wɔn mfe akɔ anim bere a wɔahu yare no taa nya nsɛnnennen pii sen wɔn a wohu sɛ wɔwɔ yare no wɔ wɔn mmofraase no. Ɛda adi sɛ eyi fi onyin hormone ne insulin-like growth factor 1 (IGF1) a wɔde wɔn ho hyɛ mu bere tenten.

Enti, sɛ wuhu nsakrae a ɛyɛ soronko a wonhwɛ kwan wɔ wo ba no nyin ne/anaasɛ ne nipadua mu su mu a, ɛho hia sɛ wo ne wɔn duruyɛfo kasa ntɛm ara sɛnea wubetumi.

Dɛn ne obi a ɔwɔ gigantism nkwa nna? Dɛn ne nsɛnnennen a ɛtra hɔ kyɛ?

Ɛho hia sɛ wohu gigantism ntɛm na wɔsa no na wɔasiw ɔsorokɔ a ɛboro so ne ɔhaw ahorow a ɛbata ho ano na ama nkwa nna akɔ soro.

Sɛ wɔansa a, gigantism ne nsɛnnennen a ɛho hia wɔ abusuabɔ na nnipa dodow a wowuwu no betumi ayɛ nea ɛtaa ba no mmɔho abien.

Nsɛnnennen a ɛtra hɔ kyɛ a nnipa binom a wɔwɔ gigantism hyia esiane wɔn tenten a ɛboro so ne nkɛntɛnso a ɛwɔ onyin hormone pii a wonya mu nyinaa nti no bi ne:

• Ɛyɛ den sɛ wobɛkɔ baabiara (Mobility) esiane ntini a ɛyɛ mmerɛw nti.
• Nnompe mu yare (nkwaa mu ɔfe).
• Peripheral Neuropathy (ntini a ɛwɔ nipadua no akyi no mu yare).
• 'Sleep Apnea'.
• Koma a ɛtrɛw (cardiomegaly) ne koma no mu ntini mu haw ahorow.
• Nsɛnnennen a ɛba nipadua mu nneɛma mu te sɛ Asikreyare a ɛto so abien.

Bio nso, nnipa a wɔwɔ gigantism a wɔansa wɔn yare no asetra betumi atew esiane ɔhaw ahorow a ɛwɔ da biara da dwumadi ahorow te sɛ ntade a wɔtɔ ne akwantu esiane sɛ wɔware dodo nti.

Bere bɛn na ɛsɛ sɛ wokɔ wo ba no oduruyɛfo nkyɛn fa abrabɔ ho asɛm?

Sɛ wɔahu sɛ wo ba no anya gigantism a, ɛho behia sɛ ɔkɔ wɔn duruyɛfo ne/anaasɛ endocrinologist nkyɛn daa na wahwɛ sɛnea ayaresa no rekɔ so na wahwɛ ahu sɛ ne hormone dodow yɛ pɛpɛɛpɛ.

Sɛ wuhu nsakrae biara wɔ wo ba no nyin ne/anaasɛ ne nipadua su mu a, ɛho hia sɛ wo ne wo ba no duruyɛfo kasa ntɛm ara sɛnea wubetumi. Ɛwom sɛ ɛnyɛ nea ɛda adi sɛ abran na ɛde ba de, nanso ɛfata sɛ wɔhwehwɛ nsakrae biara a ɛyɛ adwenem naayɛ mu. Ɛyɛ papa sɛ wohu abrannaa ntɛm, na nnipa a wɔwɔ gigantism taa tra ase a ahoɔden wom. Sɛ wowɔ nsɛmmisa bi fa wo ba no nyin ho a, nsuro sɛ wubebisa wo duruyɛfo. Wɔwɔ hɔ sɛ wɔbɛboa wo.

Nneɛma a ɛho hia sen biara a ɛsɛ sɛ wokae (Take-Home Message) .

Gigantism yɛ tebea a ɛntaa nsi nanso ebetumi ayɛ aniberesɛm. Ade a ɛho hia sen biara ne sɛ, sɛ wuhu biribi a ɛyɛ soronko anaasɛ ɛyɛ adwenem naayɛ wɔ wo ba no nkɔso ho, te sɛ ne tenten a ne nyin ntɛmntɛm sen sɛnea na wɔhwɛ kwan anaasɛ ne nsa ne ne nan akɛse a, a, wobɛhwehwɛ aduruyɛfo afotu ntɛm ara.

Kae sɛ, sɛ wohu yare no ntɛm na wosa no yare a, ɛma hokwan a ɛwɔ hɔ sɛ wo ba no bɛtra ase yiye na ɛfata no yɛ kɛse. Mma ɛnhaw wo, nnuruyɛfo wɔ hɔ sɛ wɔbɛboa wo ne wo ba no. Ka nsɛm biara a ɛhaw wo ho asɛm kyerɛ wɔn.

` Gigantism, Onyin Hormone, Pituitary Gland, Nkɔso wɔ Mmofra mu, Ɔsorokɔ a Ɛkɔ soro, Acromegaly