Momma yensua aduru titiriw yi (Sacubitril; Valsartan) a wɔde ma komayare yi ho ade.

So ɛyɛ den ma wo nso sɛ wobɛhome, wote nka sɛ wobɛtotɔ piti sɛ wobɔ mmɔden kakra mpo a? Anaasɛ wo duruyɛfo aka akyerɛ wo sɛ wowɔ komayare bi? Sɛ saa a, ebia wɔkyerɛw wo aduru bi a wɔfrɛ no Sacubitril; Valsartan (SAC-cu-bi-tril; VAL-SA-TAN) a wɔde yɛ aduru a wɔfrɛ no Valsartan (---‍; --) . Ɛtaa ba wɔ brand din `Entresto` ase. Enti, ɛnnɛ yɛbɛka saa aduru yi ho asɛm, sɛnea wɔde di dwuma, ne nea ɛsɛ sɛ yɛhwɛ yiye wɔ ho. Sɛnea wobɛka akyerɛ w’adamfo no ara pɛ.

Aduru bɛn na eyi yɛ? Dɛn nti na wɔde eyi rema?

Sɛ yɛbɛka no tiawa a, saa `Sacubitril; Valsartan` yɛ nnuru abien a wɔaka abom. Biako ne `Sacubitril` க்ய-஬ி-ட்ரில்),-க்ய-஬ி-ட்ரில் - . க்ய-஬ி-ட்ரில்), eyi yɛ aduru a ɛka `(neprilysin inhibitor)` kuw no ho. Ɔfoforo no ne `Valsartan` கா-தன்),-வலஸாட் -ஸாட்ரில் - க்ய-஬ி-ட்ரில்), eyi yɛ aduru bi dea kɔ `(angiotensin II receptor blocker - ARB)` kuw no mu. Nnuru abien yi bom yɛ adwuma. Wɔde saa aduru yi ma nnipa a wɔwɔ komayare titiriw . Koma a entumi nyɛ adwuma yiye yɛ tebea a ɛma koma no ntumi mfa mogya a ɛdɔɔso nkɔ nipadua no mu. Susuw ho hwɛ, koma no te sɛ nsu pɔmpɛ. Sɛ ɛnyɛ adwuma yiye a, ɛte sɛ nea nsu nsen nkɔ nipadua no nyinaa mu, na mogya nso nkɔ nipadua no nyinaa mu. Ɛno ne bere a nneɛma te sɛ ɔbrɛ ne ahome a ɛyɛ tiaa ba. Enti, nea aduru yi yɛ ne sɛ ɛboa ma koma no tumi de pɔmpɔ no na ɛtew adesoa a ɛda koma no so no so. Ɛtɔ mmere bi a nnuruyɛfo betumi de saa aduru yi adi dwuma wɔ ayaresa tebea afoforo nso mu. Ɛno yɛ wo duruyɛfo na obesi ho gyinae.

Dɛn na ɛsɛ sɛ meka kyerɛ me duruyɛfo ansa na mafi saa aduru yi ase?

Eyi ho hia paa. Ansa na wobɛhyɛ aseɛ anom saa aduru yi `Sacubitril; Valsartan`, ɛsɛ sɛ woka saa nneɛma yi ho asɛm kyerɛ wo duruyɛfo anaa ɔyarehwɛfo ampa. Mfa biribiara nsie.

• Sɛ wowɔ asikreyare ( Diabetes Mellitus) a, ka kyerɛ wo duruyɛfo , titiriw sɛ worenom aduru aliskiren no a.
• Sɛ wunim sɛ potassium dodow a ɛwɔ wo mogya mu no dɔɔso a .
• Sɛ wowɔ asaabo mu yare biara a .
• Sɛ wowɔ mmerɛbo mu yare biara a .
• Sɛ wowɔ mogya mmoroso a ɛba fam (` mogya mmoroso a ɛba fam` ) .
• Eyi ne `Sacubitril; Valsartan`, anaa `(Sɛ woanya nnuru a wɔfrɛ no ACE inhibitors (sɛ nhwɛso no, enalapril, lisinopril), nnuru a wɔfrɛ no angiotensin II receptor blockers (ARBs) (sɛ nhwɛso no, losartan, telmisartan), nnuru foforo biara, aduan, aduan a wɔde yɛ nneɛma, anaa nneɛma a wɔde siw ano .
• Sɛ woanyinsɛn, anaasɛ worebɔ mmɔden sɛ wubenyinsɛn a . Eyi ho hia paa, yɛbɛka eyi ho asɛm akyiri yi.
• Sɛ woyɛ ɛna a ɔma nufu a .

Sɛ wonya saa nneɛma yi wɔ w’adwenem wie a, wo duruyɛfo betumi asi gyinae pɔtee sɛ ebia saa aduru yi fata wo anaasɛ ɛnsɛ, ne sɛnea wode bɛma.

Ɔkwan bɛn so na wode aduru yi di dwuma yiye?

Sɛ worenom aduru bi a, nea ehia paa ne sɛ wode bedi dwuma yiye. Sɛ ɛnte saa a, ɛrenyɛ adwuma yiye.

• Sɛnea wɔnom: Eyi ba wɔ aduruyɛ mu. Ɛsɛ sɛ wɔde ano fa. Bɔ mmɔden sɛ wobɛnom dodow a wɔakyerɛw ama wo no, sɛnea wo duruyɛfo akyerɛ wo no pɛpɛɛpɛ, bere koro mu da biara . Saa kwan no so no, aduru no bɛyɛ adwuma saa ara.
• Sɛ wode aduan di dwuma anaasɛ wunni bi?: Wubetumi anom saa aduru yi bere a woadi anaasɛ wunnya nni. Nanso, nnipa binom betumi anya yafunu mu yaw sɛ wɔnom a wonni aduan a. Sɛ ɛba saa a, ɛbɛyɛ papa sɛ wode bɛka aduan ho.
• Gyae: Kɔ so de aduru yi di dwuma kosi sɛ wo duruyɛfo bɛka akyerɛ wo sɛ fa saa aduru yi di dwuma. Nnyae mpofirim. Sɛ ɛho hia sɛ wugyae a, wo ne wo duruyɛfo nkasa na di n’akwankyerɛ akyi.
• So wobetumi de saa aduru yi ama mmofra?: Yiw, ɛtɔ mmere bi a wobetumi de saa aduru yi ama mmofra a wɔadi afe biako pɛ wɔ komayare a wɔapaw ho. Nanso, akyinnye biara nni ho sɛ egye ɔhwɛ soronko ne aduruyɛfo hwɛ so.
• Nea ɛsɛ sɛ woyɛ sɛ wonom boro so a: Sɛ wususuw sɛ woanom aduru yi dodo, anaasɛ sɛ woanom nnuru pii wɔ akwanhyia mu a, kɔ ayaresabea dan a ɛhwɛ ntɛmpɛ a ɛbɛn wo no mu anaa frɛ beae a wɔhwɛ awuduru so ntɛm ara. Mma nsɛe bere.
• Mma nkyɛ: Eyi nso yɛ biribi a ɛsɛ sɛ yɛkae. Wɔakyerɛw saa aduru yi ama wo nkutoo, sɛ wɔde bɛsa wo tebea no. Enti, mfa saa aduru yi mma wo nnamfo, w’abusuafo, anaa w’abusua mufo afoforo da, sɛ wɔka sɛ wɔn nso wɔ ɔhaw koro no ara sɛ wo mpo a.

Sɛ woankɔ bere a wopɛ sɛ wonom nnuru a, dɛn na woyɛ?

Ɛtɔ da bi a yɛn werɛ fi sɛ yɛbɛnom yɛn nnuru. Sɛ ɛba saa a, mma ɛnhaw wo.

• Fa w’aduru no bere a woakae ara pɛ.
• Nanso, sɛ ɛkame ayɛ sɛ bere adu sɛ wobɛma wo dodow a edi hɔ bere a wokae a, twa dodow a woayera no so na fa dodow a edi hɔ no ara kwa wɔ bere a wɔahyɛ da ayɛ no mu.
• Mfa nnuru mmɔho abien da mfa nsiesie dodow a woayera no.Saa a wobɛyɛ no betumi de ɔhaw ahorow aba.

Nnuru afoforo bɛn na ɛnsɛ sɛ wɔde ka aduru yi ho, anaasɛ ebetumi de ɔhaw ahorow aba?

Eyi nso yɛ asɛm a ɛho hia paa. Saa aduru yi a wɔfrɛ no `Sacubitril; Valsartan` betumi de ɔhaw aba bere a wɔde ka nnuru afoforo bi ho no. Ɛne sɛ, ebia aduru yi a etu mpɔn no so bɛtew, anaasɛ ɛbɛkɔ soro, anaasɛ nsunsuanso foforo betumi aba.

Mma nnnom `Sacubitril; Valsartan` a ɛka ho ne nnuru yi:

* Sɛ wowɔ asikreyare a, ne aduru `(aliskiren)`.

* Ne nnuru a wɔfrɛ no `(Angiotensin-converting enzyme - ACE inhibitors)`. Sɛ nhwɛso no, nnuru te sɛ `benazepril`, `captopril`, `enalapril`, `fosinopril`, `lisinopril`, `ramipril`. Sɛ wugyae aduru a ɛte saa nom nna kakraa bi mpo a, ɛnyɛ papa sɛ wubefi ase `Sacubitril; Valsartan`. Wo ne wo duruyɛfo nka ho asɛm.

* Ne aduru `(tranylcypromine)`.

Nnuru a edidi so yi betumi ne `Sacubitril; Valsartan`. Enti, ka eyinom nso ho asɛm kyerɛ wo duruyɛfo:

• Angiotensin II receptor blockers (ARBs) ahorow afoforo. Nhwɛsoɔ: azilsartan, candesartan, eprosartan, irbesartan, losartan, olmesartan, telmisartan, anaa valsartan (sɛ worenom valsartan soronko de aka valsartan a ɛwɔ aduru yi mu ho a).
• Nnuru te sɛ `(celecoxib)`.
• `(lithium)` (aduru a wɔde ma adwenemyareɛ).
• `(NSAIDs)` - Eyinom yɛ nnuru a wɔde yi ɛyaw ne ɔfe so tew. Nhwɛsoɔ: `ibuprofen`, `naproxen`. Mpɛn pii no wobetumi atɔ eyinom wɔ nnurutɔnbea ahorow a wɔmfa nnuru nni dwuma wom, enti sɛ wode di dwuma a, ka ho asɛm.
• Nnuru a ɛma nsu fi nipadua mu a ɛmma potassium nsɛe. Nhwɛso ahorow: amiloride, spironolactone, triamterene.
• Potassium a wɔde ka ho anaasɛ nkyene a potassium pii wom a wɔde si ananmu.

Ebia nnuru a wɔde di dwuma no nyinaa nka saa nsɛm a wɔahyehyɛ yi ho. Enti, ɛho hia sɛ woka nnuru a worenom nyinaa ho asɛm kyerɛ wo duruyɛfo, a vitamin, nhabannuru, nnuru a wɔtɔn, ne nnuru a wɔde di dwuma wɔ amanne kwan so ka ho. Afei nso, di wo duruyɛfo no nokware wɔ nnuru biara a wonom, a nnuru a wonom, nsa, anaa nnubɔne afoforo a mmara mma ho kwan ka ho. Eyinom betumi aka sɛnea aduru yi yɛ adwuma yiye no.

Dɛn na ɛsɛ sɛ mehwɛ yiye wɔ ho titiriw bere a merenom aduru yi?

Yɛsrɛ sɛ hwɛ saa nsɛm yi yiye bere a wode aduru yi redi dwuma no na ama woanya ahobammɔ a ɛbɛma woanya mfaso kɛse afi aduru no mu.

• Hwɛ sɛnea yare no ho sɛnkyerɛnne: Sɛ wo komayare ho sɛnkyerɛnne (te sɛ ɔhome a ɛyɛ tiaa, ɔbrɛ, wo nan a ɛho ahonhon) no ankɔ yiye bere a woafi aduru yi ase akyi, anaasɛ sɛ ɛte sɛ nea ɛreyɛ kɛse a, ka kyerɛ wo duruyɛfo ntɛm ara.
• Nyinsɛn (eyi ho hia yiye!):

Nnyinsɛn bere a worenom Sacubitril no; Valsartan na ɔkyerɛwee. Saa aduru yi betumi apira akokoaa a ɔhyɛ yafunu mu kɛse, na ebetumi de ne nkwa mpo ato asiane mu. Enti, sɛ woreyɛ nhyehyɛe sɛ wubenyinsɛn, anaasɛ wususuw sɛ ebia woanyinsɛn a, gyae aduru yi nom ntɛm ara na ka kyerɛ wo duruyɛfo. Wo duruyɛfo bɛma wo afotu a ɛfata. Bisa wo duruyɛfo ma ɔmma no nsɛm pii.

• Dae anaa adwenemhaw: Ebia nnipa binom bɛte nka sɛ wɔda kakra anaasɛ wɔn adwene mu yɛ wɔn naa bere a wɔnom aduru yi no. Enti, kwati sɛ wobɛka kar, wode mfiri a emu yɛ duru bedi dwuma, anaa biribiara a ɛhwehwɛ sɛ wode w’adwene si biribi so na w’ani da hɔ kosi sɛ wubehu sɛnea aduru yi ka wo ankasa. Mma nsɔre mfi baabi a wotena anaasɛ ntra ase mfi baabi a wugyina hɔ mpofirim. Hwɛ yiye titiriw sɛ woabɔ akwakoraa a. Gyinabea a wɔtaa sesa no betumi atew asiane a ɛwɔ hɔ sɛ obi bɛtɔ wo tirim na wahwe ase no so.
• Nsã: Kwati nsa sɛnea wubetumi biara bere a worenom aduru yi no. Nsã betumi asiw aduru yi a etu mpɔn no kwan na ebetumi ama nea efi mu ba no ayɛ kɛse.
• Nneɛma a wɔde si nkyene ananmu: Potassium wɔ nneɛma bi a wɔde si nkyene ananmu. Ɛsɛ sɛ wohwɛ yiye wɔ wo potassium dodow ho bere a worenom aduru yi, enti mfa nnuru a wɔde si nkyene ananmu nni dwuma gye sɛ wo duruyɛfo ka kyerɛ wo pɔtee.

Dɛn ne aduru yi mu nsunsuanso bɔne a ebetumi afi mu aba?

Te sɛ aduru biara no, Sacubitril; Valsartan betumi de ɔhaw ahorow aba nnipa binom so. Ɛnyɛ obiara na onya bi, nanso eye sɛ wobɛma w’ani ada hɔ. Sɛ wunya nneɛma bɔne a edidi so yi mu biara a, ka kyerɛ wo duruyɛfo anaa ayaresabea ntɛm ara sɛnea wubetumi:

• Nneɛma a ɛma obi ho yɛ no hyew:
• Wora mu akuru, ɛte sɛ eczema, ɛyaw, akisikuru.
• Anim, ano, tɛkrɛma, anaa menewa a ɛho ahonhon (eyi yɛ asiane kɛse efisɛ ebetumi ama ahome ayɛ den).
• Potassium dodow a ɛkɔ soro wɔ mogya mu:
• Sɛ wote nka sɛ wo koko mu yɛ wo yaw.
• Koma a ɛbɔ ntɛmntɛm na ɛnyɛ nea ɛkɔ so daa mpofirim.
• Mmerewa ne ntini a ɛyɛ mmerɛw a wɔte nka.
• Asaabo mu opira:
• Sɛ wote nka sɛ ɛyɛ den sɛ wobɛtow nsu.
• Nsu kakraa bi anaa pii a wɔde fa mu sen sɛnea wɔtaa yɛ no.
• Nsu kɔla a ɛsakra.
• Mogya mmoroso a ɛba fam:
• Sɛ wote nka sɛ wo ho ayɛ wo hyew, titiriw bere a wogyina hɔ no.
• Ɔte nka sɛ wayɛ mmerɛw, n’aniwa dan bruu.
• Te a wobɛte nka sɛ wobɛhwe ase bere a wugyina hɔ no.
• Sɛ́ wobɛte nka sɛ wayɛ mmerɛw na wabrɛ wɔ ɔkwan soronko so.

Mpɛn pii no, nsunsuanso bɔne a wɔabobɔ din wɔ ase ha no nyɛ biribi a ɛsɛ sɛ wohaw wo ho wɔ ho. Nanso sɛ wɔkɔ so anaasɛ wɔhaw wo a, ka kyerɛ wo duruyɛfo sɛ:

• Ɔfe: Ebia nnipa binom benya ɔfe a ɛyɛ dry bere a wɔrenom aduru yi no.

Sɛ wunya sɛnkyerɛnne anaa nsunsuanso bɔne bi a ɛyɛ soronko a wɔankyerɛw wɔ ha a, wo ne wo duruyɛfo nka ho asɛm. Mma ɛnhaw wo, wobetumi adi saa nneɛma yi mu dodow no ara ho dwuma.

Wobɛyɛ dɛn akora saa aduru yi so yiye?

Ɛho hia paa nso sɛ wode nnuru sie.

• Fa sie baabi a mmofra ne afieboa ntumi nkɔ hɔ. Eyi abu so wɔ nnuru nyinaa mu.
• Fa sie wɔ dan mu hyew (a ɛyɛ digrii Celsius 20 kosi 25, digrii Fahrenheit 68 kosi 77 ntam). Bɔ wo ho ban fi ɔhyew, hann, ne nsu a ɛboro so ho. Eyi kyerɛ sɛ ɛnsɛ sɛ wode nneɛma sie wɔ mmeae te sɛ aguaree.
• Fa toa anaa packet a aduru no wom no to mu denneennen.
• Mfa nnuru a ne bere atwam nni dwuma. Wɔaka da a ɛbɛba awiei ho asɛm wɔ krataa no so.

Ɔkwan bɛn so na wotow nnuru a wɔmfa nni dwuma anaasɛ ne bere atwam gu?

• Adeɛ a ɛyɛ papa sɛ wobɛyɛ ne sɛ wode nnuru no bɛma ``take-back program.'' Hwɛ wo nnurutɔnbea anaa polisifoɔ adwumayɛbea a ɛbɛn wo na hwɛ sɛ wɔwɔ nhyehyɛeɛ a ɛte saa anaa.
• Sɛ ɛno ntumi nyɛ yiye a, hwɛ nnuru a wɔakyerɛw so anaa nea wɔde ahyɛ mu no mu hwɛ sɛ akwankyerɛ bi wɔ hɔ a ɛkyerɛ sɛnea wobɛtow nnuru no agu nwura mu anaasɛ wobɛhohoro agu tiafi mu anaa.
• Sɛ wunnye nni a, bisa wo duruyɛfo anaa nnuruyɛfo.
• Sɛ ɛyɛ aduru a wobetumi atow agu nwura mu a, yi fi ade no mu, fa fra mpataa nwura, dɔte, anaa kɔfe a wɔde adi dwuma, fa gu kotoku anaa ade a wotumi to mu mu, na tow gu nwura mu. Eyi yɛ nea wɔde siw mmofra nkumaa anaa mmoa ano na wɔankɔ mu na wɔamfa akwanhyia aba.

Nneɛma a ɛho hia sen biara a ɛsɛ sɛ wode sie w’adwenem (Take-Home Message) .

Okay, enti yɛaka saa aduru yi ho asɛm pii `Sacubitril; Valsartan` (Entresto), ɛnte saa? Nea etwa to no, nneɛma a ɛho hia sen biara a ɛsɛ sɛ yɛma ɛtra yɛn adwenem ni:

• Saa aduru yi yɛ aduru a ɛho hia a ɛboa ma wodi wo koma a entumi nyɛ adwuma yiye no so.
• Fa dodow a wɔakyerɛw ama wo no bere nyinaa, sɛnea wo duruyɛfo akyerɛ wo no. Mma nntwa adidi anaasɛ nnom pii nsen nea wuhia.
• Hwɛ hu sɛ wobɛka nnuru foforo biara a wonom ne nyarewa foforo biara a wowɔ ho asɛm akyerɛ wo duruyɛfo.
• Sɛ woanyinsɛn anaa worebɔ mmɔden sɛ wubenyinsɛn a, nnom saa aduru yi. Hwɛ yiye titiriw.
• Hwɛ nneɛma bɔne a efi mu ba no yiye. Sɛ wuhu biribi a ɛyɛ soronko a, ka kyerɛ wo duruyɛfo.
• Sɛ wowɔ nsɛmmisa anaa adwenem naayɛ bi a, mma wofɛre sɛ wubebisa wo duruyɛfo anaa nnuruyɛfo.

Sɛ wudi anammɔn yi akyi yiye a, saa aduru yi betumi ama woanya nneɛma pa ama wo koma akwahosan. Mepɛ sɛ wo ho tɔ wo ntɛm! Sacubitril, Valsartan, Entresto, Koma a Ɛnyɛ Den, Koma Yare, Koma Nnuru, Mogya Nhyɛso