Yala a delila ka gɛlɛya i ma ka i ka kolosinsinnanw kunbɛn, hali ni i ye fura suguya caman kɛ, ka dumuni suguya caman kɛ ani ka farikoloɲɛnajɛ kɛ wa? Tuma dɔw la, o bɛ kɛ. O ye gɛlɛya ye kɛrɛnkɛrɛnnenya la ni kolosinsinnan caman bɛ aw ka denbaya kɔnɔ. Bi, an bɛ kuma fura suguya kura dɔ kan min bɛ se ka dɛmɛ don. Olu bɛ wele ko PCSK9 balilanw.
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Nin PCSK9 balilanw ye mun ye?
N’an y’a fɔ cogo nɔgɔman na, ninnu ye kolosinsinnan fura barikamaw ye minnu bɛ kɛ pikiri ye. U bɛ LDL kolosinsinnanw de laɲini fɔlɔ (Low-Density Lipoprotein Cholesterol) , o ye "kolosɛri juguman" ye, an bɛɛ b’a dɔn ko a man ɲi an farikolo ma. A ka ca a la dɔgɔtɔrɔw bɛ o furaw di mɔgɔw ma minnu ka kolosinsinnan fura wɛrɛw ma nɔ ɲininen sɔrɔ, i n’a fɔ statini, walima mɔgɔ minnu ka denbaya kɔnɔ kolosinsinnan caman bɛ u la.
Nin fura in bɛ baara kɛ cogo di farikolo kɔnɔ?
Walasa k’o faamu, an ka misali fitinin dɔ ta. Miiri k’a filɛ ko kolosinsinnan jugu (LDL) min bɛ aw joli la, o ye nɔgɔ sugu dɔ ye. Walasa ka o nɔgɔ in bɔ ka joli saniya, an ka sugunɛ bɛ "nɔgɔbɔlan" kɛrɛnkɛrɛnnen dɔ kɛ a sanfɛla la. an bɛ min wele furakɛli siratigɛ la , o ye LDL minɛbagaw ye . O furakisɛw bɛ min kɛ, o ye ka LDL kolosinsinnan minɛ joli la ka taa n’a ye sugunɛ na walasa a ka tiɲɛ.
Sisan, dɔ wɛrɛ bɛ na yan. o ye farikolojɔlan ye min bɛ wele ko PCSK9 . O fana bɛ Bɔ an ka sugunɛ na. Nka nin PCSK9 furakisɛ in baara ye ka LDL minɛbagaw (an ka nɔgɔbɔlanw) tiɲɛ minnu bɛ kolosinsinnanw bɔ. Ni PCSK9 hakɛ cayara farikolo la, LDL sɔrɔyɔrɔ caman bɛ tiɲɛ. O kɔ, kolosinsinnan bɔli joli la, o bɛ dɔgɔya, kolosinsinnan hakɛ bɛ caya joli la.
O la, PCSK9 balilan boloci bɛ min kɛ, o ye ka o PCSK9 farikolojɔlifɛn tiɲɛnen in bali k’a bali ka baara kɛ. O kɔ, an ka LDL sɔrɔyɔrɔw tɛ tiɲɛ, wa u bɛ se ka baara kɛ hɔrɔnya la. O kɔlɔlɔ ye ko LDL kolosinsinnan caman bɛ bɔ joli la, ani kolosinsinnan hakɛ bɛ dɔgɔya kosɛbɛ. A ka nɔgɔn kosɛbɛ, tiɲɛ tɛ?
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Check Availability →Nin fura in ka ɲi jɔn ma?
Nin tɛ fura ye min bɛ kɛ mɔgɔ kelen-kelen bɛɛ la. Aw ka dɔgɔtɔrɔ bɛna a latigɛ ni fura in bɛnnen don aw ma ka da fɛn caman kan.
| Sigisariyaw | Cogojirali |
|---|---|
| Kolosinsinnan caman min tɛ fura wɛrɛw kunbɛn | Ni aw ka LDL hakɛ bɛ caya hali bi hali ni aw ye statini ni kolosinsinnan fura wɛrɛw tata hakɛ cayalenba ta. |
| Kɔnɔbolibana minnu bɛ sɔrɔ cɛya la, olu bɛ sɔrɔ cɛya la | Mɔgɔ minnu ka kolosinsinnan hakɛ ka ca kosɛbɛ kabini u denmisɛnman ka a sababu kɛ u ka jamu banaw ye i n’a fɔ denbaya kɔnɔ kolosinsinnan. |
| Mɔgɔ minnu ka dusukunnabana farati ka bon kosɛbɛ | Ni dusukun tantanni walima kirinni kɛra aw la kaban, ani ni o bana sugu bɛ se ka kɛ don nataw la, o farati ka bon kosɛbɛ. |
Ne bɛ se ka fura in sɔrɔ cogo di?
Olu bɛ kɛ pikiri ye, a tɛ kɛ furakisɛ ye. Ka kɛɲɛ ni dɔgɔtɔrɔ ka laadilikan ye, a ka ca a la, aw bɛna nin pikiri in kɛ dɔgɔtɔrɔso la walima dɔgɔtɔrɔso la dɔgɔkun damadɔ walima kalo damadɔ o kalo damadɔ. A suguya belebele fila minnu bɛ kɛ Sri Lanka sisan, olu ye Alirocumab (Praluent®) ani Evolocumab (Repatha®) ye .
Nin furakɛli in daminɛ kɔfɛ, aw ka dɔgɔtɔrɔ bɛna joli sɛgɛsɛgɛli kɛ tuma bɛɛ ani ka aw ka kolosinsinnan hakɛ kɔlɔsi walasa k’a dɔn a bɛ se ka kɛ cogo min na.
Nafa ni kɔlɔlɔ jumɛnw bɛ a la?
Nin fura in nafa fɔlɔ ye ko a bɛ se ka LDL kolosinsinnan hakɛ dɔgɔya kosɛbɛ. Ka kɛɲɛ ni sɛgɛsɛgɛli dɔw ye, u bɛ se ka LDL hakɛ dɔgɔya ni 50% ni 70% cɛ . O bɛ dɔ bɔ kosɛbɛ dusukun tantanni, sɔgɔsɔgɔninjɛ ani dusukunnabana wɛrɛw la.
Hali ni kɔlɔlɔ jugumanw tɛ mɔgɔ fanba la, dɔw bɛ se ka kɔlɔlɔ misɛnniw sɔrɔ.
- Funu, bilenni walima dimi pikiri kɛyɔrɔ la
- Sɛgɛn sɔrɔli (Sɛgɛn) .
- Farikolodimi
- Farigan taamasiɲɛw
A man teli kosɛbɛ, mɔgɔ dɔw bɛ se ka nɔ dɔw sɔrɔ u sugunɛ walima u sugunɛ baara la. o de kama a nafa ka bon kosɛbɛ ka taa dɔgɔtɔrɔso la tuma bɛɛ walasa ka sɛgɛsɛgɛli kɛ . Ni aw ye taamasiɲɛ dɔw ye minnu tɛ deli ka kɛ, aw bɛ o fɔ aw ka dɔgɔtɔrɔ ye joona.
Yala fura in dɔrɔn tali man bɔ wa?
Nin ye ɲininkali ye min nafa ka bon kosɛbɛ. Jaabi ye ko: "Ayi, a ma se." PCSK9 balilanw tɛ majigi ye. U ye furakɛli bolodacogo bɛɛ lajɛlen yɔrɔ kelen dɔrɔn de ye.
Aw ye aw hakili to a la ko kolosinsinnanw kunbɛnni tɛ furakisɛ tali dɔrɔn ye. O ye ka i ka ɲɛnamaya kɛcogo bɛɛ Changer.
Ni aw bɛ nin boloci in ta, aw ka kan ka aw janto ninnu na sisan:
- Dumuni nafama dunni: Aw bɛ tulu ni sukaro ni kɔgɔ dɔɔni dun, ka jiridenw ni nakɔfɛnw ni dumuni caman dun minnu nafa ka bon.
- Farikoloɲɛnajɛ kɛli tuma bɛɛ: Aw bɛ farikoloɲɛnajɛ kɛ i n’a fɔ taama walima boli miniti 30 ni kɔ tile kɔnɔ, a dɔgɔyalenba tile 5 dɔgɔkun kɔnɔ.
- Degunw kunbɛnni: Ka hakili lafiya fɛnw fɛ i n’a fɔ yoga ani hakilijakabɔ.
- Sunɔgɔ ka ɲɛ: Aw bɛ sunɔgɔ ɲuman kɛ lɛri 7-8 don o don.
- Sigarɛtimin dabila: Sigarɛtimin ni sigarɛtimin dabila pewu.
Aw bɛna nɔ ɲuman sɔrɔ PCSK9 balilan furakɛli la ni aw ye nin ɲɛnamaya kɛcogo caman ɲɔgɔn na. Aw kana fura tali dabila abada walima ka a tata hakɛ Changer ni dɔgɔtɔrɔ ma a laadi.
Take-Home cikan
- PCSK9 balilanw ye pikiri suguya barikama ye min bɛ kɛ ka LDL kolosinsinnan hakɛ caman dɔgɔya, furakɛli wɛrɛw tɛ minnu kunbɛn.
- O bɛ sugunɛ ka LDL sɔrɔyɔrɔw tanga ani ka kolosinsinnan bɔli kɛcogo kɛ joli la ka ɲɛ.
- Nin ye furakɛli ye dɔgɔtɔrɔ bɛ min fɔ bana kɛrɛnkɛrɛnnenw dɔrɔn de kama (misali la, kolosinsinnan caman bɛ sɔrɔ cɛya la, dusukunnabana farati ka bon).
- A nafa ka bon kosɛbɛ ka ɲɛnamaya kɛcogo ɲuman mara ka a sɔrɔ aw bɛ furakɛli in kɛ.
- Aw bɛ nin furakɛli in tɛmɛ ni aw ka dɔgɔtɔrɔ ka laadilikan dɔrɔn ye, aw bɛ to ka kuma a fɛ tuma bɛɛ.
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