Ðe ɖeɖi tea ŋuwò zi geɖe, ɖe nèwɔa avu kple nuɖuɖumeŋusẽ ƒe kuxi siwo nɔa anyi ɖaa, alo ɖe aɖuɖɔtoe si womenya o la dzɔa dzi na wòa? Ðe nèle dzesi dem ŋutigbalẽ ƒe tɔtrɔ siwo mebɔ o alo nèle avu wɔm kple ŋkuɖoɖonudzi ƒe dɔmawɔmawɔ nyuiea? Togbɔ be woate ŋu atsɔ dzesi siawo asɔ kple nɔnɔme vovovowo hã la, woate ŋu aƒo nu tso lãmesẽnya aɖe koŋ ŋu, si dzi woŋea aɖaba ƒuna zi geɖe. Egbea la, míele nu ƒom tso dɔléle aɖe si woyɔna be Pellagra ŋu .
Nukae nye Pellagra?
Kpuie ko la, Pellagra nye dɔléle si dona tso Niacin , si wogayɔna be Vitamin B3 , si mesɔ gbɔ o gbɔ. Esia nye nunyuimakpɔɖu ƒomevi aɖe koŋ—vevietɔ, nunyiame suesuesuewo ƒe anyimanɔmanɔ. Wò ŋutilã hiã Niacin be lãmenugbagbeviwo nawɔ dɔ nyuie wu. Ne agbɔsɔsɔa ɖiɖi la, wokpɔa ŋusẽ si wòkpɔ ɖe wò ŋutilã bliboa dzi, vevietɔ le ŋutigbalẽ, nu, nuɖuɖumeŋusẽ, kple ahɔhɔ̃ me. Ne atikewɔlawo mewɔ nu nyuie o la, Pellagra ate ŋu ana lãmekawo nagblẽ tegbee eye le nɔnɔme sesẽwo me la, ate ŋu awu ame.
Ðewohĩ àbia ɖokuiwò be ɖe esia kpɔa ŋusẽ ɖe amesiame dzi hã. Zi geɖe la, amesiwo ɖua nuɖuɖu si da sɔ la xɔa Niacin si sɔ. Wokpɔa Pellagra gbãtɔ—si nuɖuɖu ƒe anyimanɔmanɔ hena vɛ—le nuto siwo me nuɖuɖu mele o me koŋ. Gake le nuto deŋgɔ siwo dome Sri Lanka hã le me la, zi geɖe la, nu evelia gbɔe Niacin ƒe anyimanɔmanɔ tsona. Esia fia be lãmesẽkuxi alo nu bubu siwo le megbe na wò la le mɔ xem na wò ŋutilã be wòagaxɔ Niacin si nènona alo azãe o.
Nukae nye Niacin, eye nukatae nèhiãe?
Bu Niacin be enye mɔ̃memi si nana wò ŋutilã ƒe “mɔ̃” wɔa dɔ nyuie. Abe alesi mɔ̃ hiã mɔ̃memi si ŋu wokɔ hafi wòate ŋu awɔ dɔ ene la, nenema ke wò ŋutilã hã hiã Niacin be wòatrɔ asi le nuɖuɖumeŋusẽ si nèzãna ŋu wòazu ŋusẽ si nàte ŋu azã.
Ne wonya xɔ Niacin to wò dɔgbo suea me ko la, etrɔna zua coenzyme vevi aɖe si woyɔna be Nicotinamide Adenine Dinucleotide (NAD) . NAD doa alɔ enzyme siwo wu 400 le wò ŋutilã me. Kpuie ko la, NAD le vevie ŋutɔ be woatsɔ awɔ lãmenugbagbeviwo ƒe ŋusẽ si woyɔna be Adenosine Triphosphate (ATP) . Le ŋusẽ wɔwɔ godo la, NAD le vevie ŋutɔ na DNA dzadzraɖo kple lãmenugbagbeviwo ƒe kadodo.
Aleke Niacin ƒe anyimanɔmanɔ kpɔa ŋusẽ ɖe wò ŋutilã dzii?
Esi wònye be NAD nye nu vevi aɖe na lãmenugbagbeviwo ƒe ŋusẽ ta la, gbɔdzɔgbɔdzɔ aɖe dzea nuɖoanyi siwo hiã ŋusẽ geɖe alo lãmenugbagbeviwo ƒe tɔtrɔ kabakaba dzi: wò ŋutigbalẽ, wò dɔgbo ƒe lãkusi, kple wò ahɔhɔ̃. Zi geɖe la, ɖɔktawo ɖɔa Pellagra ƒe dzesi ɖedzesiwo be “3 D”: Aɖuɖɔtoe, Ŋutilãmedɔ, kple Tagbɔdɔléle. Ame aɖewo tsɔ “D” enelia kpena ɖe eŋu: Ku . Ne womewɔ atike nɛ ɣeyiɣi didi o la, emetsonua ate ŋu awu ame.
1. Aɖuɖɔtoe (Dɔɖuɖɔtoedɔléle) .
Aɖuɖɔtoetetedɔ dzɔna ne wò nuɖuɖumeŋusẽ ƒe ametakpɔnu mete ŋu trɔna nyuie o. Ne ametakpɔnu sia meli o la, wò dɔgboa ʋlina vevie be yeaɖu nuɖuɖu eye yeakpɔ ye ɖokui ta tso dɔlékuiwo kple abixɔxɔ me. Esia hea abi si nɔa anyi didi vɛ le nuɖuɖumeŋusẽ katã me, si dzena abe ƒodo ƒe vevesese, nuɖuɖumaɖumaɖu, nu me ƒe abi, kple aɖe si vuvu, si biã ene.
2. Dermatitis (Ŋutilã ƒe keklẽŋusẽ) .
Pellagra hea ŋutigbalẽ ƒe nɔnɔme si to vovo vɛ, vevietɔ le teƒe siwo ɣe ƒe keklẽ dzena le abe mo, kɔ, asiwo, kple afɔwo ene. Ne lãmenugbagbeviwo ƒe ŋusẽ mesɔ gbɔ o la, ŋutigbalẽmenugbagbeviwo va sea UV keklẽ nu fũ akpa. Le gɔmedzedzea me la, ŋutigbalẽa ate ŋu adze dzĩ eye ŋdɔkutsu dzatsɛ, eye mlɔeba la, azu ƒuƒlu, aŋɔ, eye wòava zu kpe siwo ƒe amadede sɔ gbɔ akpa (teƒe siwo do viviti) . Dzesi aɖe si ɖe dzesi enye ka ɣi aɖe si le kɔ si woyɔna be “Casal ƒe kɔla,” si wotsɔ atikewɔla Don Gaspar Casal, amesi de dzesi dɔlélea zi gbãtɔ le ƒe 1735 me la ƒe ŋkɔ.
3. Tagbɔdɔléle (Ahɔhɔ̃ kple lãmekawo ƒe gbegblẽ) .
Esi wònye be Pellagra kpɔa ŋusẽ ɖe ŋusẽ ƒe wɔwɔme dzi le lãmenugbagbevi ɖesiaɖe me ta la, ekpɔa ŋusẽ ɖe ahɔhɔ̃ kple lãmekawo dzi mlɔeba. Dzesi gbãtɔwo ate ŋu anye esiwo menya kpɔna dzea sii bɔbɔe o, abe ɖeɖiteameŋu atraɖii, ɖekematsɔleme (ɖekematsɔlememanɔamesi), alo susu ƒe dɔwɔwɔ sesẽ ene. Àte ŋu akpɔ dzimaɖitsitsi alo blanuiléle hã.Le ɣeyiɣi aɖe megbe la, dzesi siawo ate ŋu adzi ɖe edzi ava zu tɔtɔ kple susuhenuwo. Le nɔnɔme sesẽwo me la, tagbɔdɔléle si nɔa anyi ɖaa ate ŋu adzɔ, tsɔ kpe ɖe ahɔhɔ̃mekawo ƒe dɔmawɔmawɔ nyuie abe dadasɔ nyuie o, azɔlizɔzɔ ƒe tɔtɔ, lãmekawo ƒe ʋuʋu, kple ʋuʋudedi ene ŋu.
Afikae Pellagra bɔ ɖo wu?
Le ŋutinya me la, Pellagra bɔ ɖe ameha siwo ƒe nuɖuɖu mesɔ gbɔ o dome, vevietɔ amesiwo ɖoa ŋu ɖe bli (bli) ŋu vevie be enye nuɖuɖu vevitɔ evɔ womekpɔa nuɖuɖu siwo me protein sɔ gbɔ ɖo o. Togbɔ be Niacin le bli me hã la, ele nɔnɔme si “bla” si amegbetɔ ƒe ŋutilã mate ŋu axɔ bɔbɔe o me.
Le Titina kple Anyiehe Amerika la, mɔnu siwo wozãna tsã tsɔ trɔa asi le bli ŋu wòzua tortilla bia be wotsɔa nukua dea lime tsi me. Dɔwɔwɔ sia ɖea Niacin si wobla la ɖe go, si wɔnɛ be wòte ŋu nɔa agbe. Eyata ƒã hafi wokpɔa Pellagra ( Pellagra ) le nuto mawo me.
Egbea la, nu veviwo abe wɔ kple bli ene ƒe ŋusẽdodo ɖe Pellagra gbãtɔ dzi kpɔtɔ ŋutɔ le xexeame ƒe akpa geɖe. Gake togbɔ be ƒã hã la, ele be míanɔ ŋudzɔ le nu evelia siwo gbɔ Pellagra tsona ŋu. Ne èsusu be dzesi siawo le ye ŋu la, te ɖe kɔdzi si te ɖe ŋuwò alo dɔwɔƒe si kpɔa nudzɔdzɔ kpatawo gbɔ enumake.
Nukae nye Pellagra ƒe dzesiwo?
Dzesi siwo bɔ siwo nàte ŋu ade dzesii le Pellagra ŋue nye esi:
- Aɖuɖɔtoe si nɔa anyi ɖaa , si ate ŋu anye ʋu ɣeaɖewoɣi.
- Ƒodo ƒe vevesese kple nuɖuɖu ƒe dɔmawɔmawɔ nyuie .
- Nuɖuɖu ƒe dzodzro ƒe vɔvɔ , ʋuʋudedi , kple ʋuʋudedi .
- Ŋutilã si le ʋuʋum alo ŋutigbalẽ ƒe ʋuʋudedi si le veve sem .
- Nu me abi kple aɖe si le dzo dam eye wòvuvu.
- Ðeɖiteameŋu sesẽ, gbɔdzɔgbɔdzɔ, kple seselelãme si nye be yeƒe lãme sẽ.
- Seselelãme ƒe tɔtrɔ kple blanuiléle.
- Ahɔhɔ̃mekawo ƒe dzesiwo – le kpɔɖeŋu me, abɔwo kple afɔwo ƒe ʋuʋu alo lãmetutudɔ.
- Delirium kple tagbɔdɔléle ƒe dzesiwo.
Nukawoe hea Pellagra vɛ?
Nusi koŋ gbɔ wòtsoe nye nuɖuɖu si me niacin (Vitamin B3) si sɔ mele o. Togbɔ be míekpɔa niacin tso nuɖuɖu vovovowo me hã la, ame ɖekaɖeka siwo si nunyiame si da sɔ mele o ate ŋu azu nusiwo mehiã o.
Tsɔ kpe ɖe eŋu la, àte ŋu axɔ pellagra le nu evelia siwo gbɔ wòtso ta . Esia fia be wò ŋutilã mete ŋu xɔa niacin alo zãnɛ nyuie o le lãmesẽkuxi aɖe si le eme ta. Kpɔɖeŋu aɖewoe nye:
- Dɔgbo ƒe dɔléle siwo hea dɔgbo ƒe dɔmawɔmawɔ nyuie vɛ – abe Inflammatory Bowel Disease (IBD) alo aklã ƒe ʋuʋu ene.
- Ahanono ƒe kuxi: Ahanono fũ gblẽa nu le ŋutinuwo abe aklã ene ŋu, si wɔnɛ be nunyiame veviwo abe niacin ene ƒe xɔxlɔ̃ me gblẽna eye wòhea nunyuimakpɔɖui vɛ le afisiafi.
- Dɔgbo ƒe dɔwɔwɔ: Le amekoko megbe la, dɔgboa ƒe lãkusi ƒe gbegblẽ ate ŋu ado kplamatse nunyiame suesuesue veviwo, siwo dome niacin hã le, ƒe xɔxlɔ̃.
- Ʋusɔgbɔdɔ si me iron mele o: Wò ŋutilã hiã iron be wòatrɔ niacin nyuie ahazãe.
- Hartnup dɔléle: Domenyiŋusẽfianu ƒe nɔnɔme si me ŋutilãa ʋlina vevie be yeaxɔ amino acid aɖewo siwo hiã hena vitaminwo wɔwɔ.
- Dɔdzẽ ƒe dɔléle:Dɔdzẽ ƒe lãmenugbagbevi aɖewo ate ŋu aɖe ŋutilãa ƒe niacin wɔwɔ dzi akpɔtɔ.
- Atike aɖewo: Vevietɔ atike aɖewo siwo tsia ʋuʋudedi nu kple atike siwo ate ŋu ado kplamatse niacin ƒe lãmenugbagbeviwo ƒe dɔwɔwɔ.
- HIV dɔlékui xɔxɔ: HIV ate ŋu ana niacin ƒe agbɔsɔsɔ naɖiɖi le ŋutilã me.
Aleke wokpɔa Pellagra ƒe dɔléleae?
Ne èyi ɖɔkta gbɔ la, woado wò kpɔ, alé ŋku ɖe wò dɔlélea ƒe dzesiwo, atikewɔwɔ ŋutinya, kple nuɖuɖu ƒe nɔnɔmewo ŋu. Ne wò ɖɔkta susu be pellagra la, ate ŋu aɖe gbe be woado aɖuɖɔ kpɔ be woatsɔ adzidze atike aɖewo ƒe agbɔsɔsɔ, si akpe ɖe ŋuwò nànya ne niacin le wò ŋutilã xɔm wòsɔ gbɔ. Wò ɖɔkta ate ŋu aŋlɔ niacin kpeɖeŋutɔ hã na wò be wòakpɔe ɖa be wò dzesiwo nyo ɖe edzi hã; atikewɔwɔ dodokpɔ sia nye dɔlélewo didi ƒe mɔnu bubu si bɔ si wozãna le Nirogi Lanka kple atikewɔƒe bubuwo.
Nukawoe nye Pellagra ƒe atikewo?
Esi wònye be niacin (Vitamin B3) ƒe anyimanɔmanɔ gbɔe pellagra tsona ta la, atikewɔwɔ si wɔa dɔ wue nye be woagbugbɔ nunyiame si bu la aɖo to niacin kpeɖeŋutɔ me. Ame akpa gãtɔ dzea egɔme ƒe lãme sẽna kabakaba ne wonya dze atikewɔwɔ gɔme ko. Gake àte ŋu ahiã beléle bubuwo ɖe dzesi evelia abe ŋutigbalẽ alo nu me abi ene ŋu.
Vevietɔ wu la, ne dɔléle evelia aɖe gbɔe wò pellagra tso la, ele be nàxɔ atikewɔwɔ si sɔ na atikewɔwɔ me nya ma si le ete.
Ðe atikewɔwɔa ƒe nugbegblẽ le ame ŋua?
Ne ènoe abe alesi wò ɖɔkta gblɔe ene la, ƒã hafi niacin-tikewo hea nugbegblẽ le ame ŋu vevie vɛ. Zi geɖe la, ne wozã atike wògbɔ eme ko hafi wògblẽa nu le ame ŋu, si nye nusi mate ŋu adzɔ le amesi ƒe dɔmawɔmawɔ nyuie ƒe dɔmawɔmawɔ nyuie me o. Ne wodzɔ la, woate ŋu anye:
- Ŋutilã ƒe ʋuʋu.
- Ʋuʋudedi alo ʋuʋudedi.
- Ʋuʋudedi kple nuɖuɖu ƒe dɔmawɔmawɔ nyuie.
- Taɖuame kple taɖuame.
Aleke nàwɔ axe mɔ ɖe Pellagra nu?
Nuɖuɖu si da sɔ nyuie me léle ɖe asi nye mɔ bɔbɔetɔ kekeake si dzi woato akpɔ egbɔ be nunyiame si sɔ nasu ame si. Ne nuɖuɖu ʋɛ aɖewo koe le asiwò la, nuɖuɖu siwo me nunyiame le kple nuɖuɖu siwo wotsɔ kpe ɖe nuɖuɖu ŋu ate ŋu akpe ɖe ŋuwò. Zi geɖe la, ame tsitsi si le lãmesẽ me hiãa niacin si ade 15mg gbesiagbe, si zi geɖe la, vitamin B-complex ƒe kpeɖeŋutɔ naae.
Nuɖuɖu siwo me niacin sɔ gbɔ ɖo dometɔ aɖewoe nye:
- Nyilã ƒe aklã
- Beets-wo
- Brewer ƒe amɔwɔʋãnu
- Abolo kple nuku siwo me wode nuɖuɖui
- Tɔmelã siwo me ami le, abe salmon kple tuna ene
- Anyigbadzobonuwo
- Mɔli
- Koklolã
- Mᴐli
- Sunflower ƒe nukuwo
- Spaghetti-mi si wotsɔa lãmi wɔe
Ne lãmesẽkuxi aɖe si nɔa anyi didi si nana be pellagra xɔxɔ ƒe afɔkua dzina ɖe edzi la, ƒo nu kple wò ɖɔkta tso mɔxexe ɖe dɔlélea nu ɣeyiɣi didi ƒe mɔnu aɖe ŋu, si ate ŋu abia be nàtrɔ asi le wò nuɖuɖu, kpeɖeŋutɔ, alo atike siwo nèzãna fifia ŋu.
Ɣeyiɣi didi kae wòxɔna hafi wòhayana tso Pellagra me?
Ne ènya dze niacin kpeɖeŋutɔ nono gɔme ko la, ame geɖe dea dzesii be yeƒe lãme sẽ le ŋkeke ʋɛ aɖewo ko me. Zi geɖe la, dɔgbo ƒe dzesiwo (abe aɖuɖɔtoe ene) nu tsona gbã , zi geɖe le kwasiɖa gbãtɔ me. Ŋutilã kple nu me ƒe abi ate ŋu axɔ kwasiɖa eve hafi woahaya. Dɔléle sesẽwo ate ŋu axɔ ɣeyiɣi didi wu. Taflatse de dzesii: ahɔhɔ̃mekawo ƒe gbegblẽ vevie kple tagbɔdɔ ate ŋu anye esiwo womate ŋu atrɔ o ɣeaɖewoɣi.
Ðɔktawo kafui be woalé nuɖuɖu si da sɔ me ɖe asi be woaxe mɔ ɖe pellagra gbãtɔ nu le etsɔme. Zi geɖe la, niacin ƒe anyimanɔmanɔ sɔ kple nunyiame sue bubuwo ƒe anyimanɔmanɔ, eye woate ŋu akpɔ esiawo katã gbɔ to nuɖuɖu nyui me.
Pellagra evelia dada sesẽ wu. Togbɔ be kpeɖeŋutɔtikewo kpena ɖe ame ŋu hã la, ɖewohĩ womasɔ gbɔ ne wò ŋutilã mete ŋu trɔa asi le niacin ŋu nyuie o. Le nɔnɔme siawo me la, hayahaya nɔ te ɖe dɔléle si gbɔ wòtso la didi kple edada dzi bliboe, si ate ŋu anye nusi axɔ ɣeyiɣi didi.
Gbedasi Mamlɛtɔ si Wotsɔ Yi Aƒeme
Togbɔ be woɖea pellagra gbãtɔ ɖa le nuto deŋgɔwo me koŋ hã la, egakpɔtɔ nye afɔku na ameha siwo mekpɔa nuɖuɖu boo o. Le míaƒe hadomegbenɔnɔ me la, niacin ƒe anyimanɔmanɔ evelia gakpɔtɔ nye nusi ŋu wotsi dzi ɖo le ahatsunono kple lãmesẽkuxi siwo le eme ta—vevietɔ esiwo gblẽa nu le nunyiamewo ƒe xɔxlɔ̃ ŋu. Ne èsusu be dzesi siawo le ye ŋu la, di mɔfiame tso atikewɔla aɖe gbɔ le kɔdzi si le mia gbɔ enumake.
Nu vevitɔ si dzi wòle be nàɖo ŋkui enye be togbɔ be nunyiame dzea egɔme tso nuɖuɖu si nèɖuna dzi hã la, wò ŋutilã ƒe ememe dɔwɔwɔwoe afia wò nyonyo ŋutɔŋutɔ. Wò ŋutilã ɖoa ŋu ɖe ememe dɔwɔwɔ sesẽwo ŋu be wòanɔ lãmesẽ me. Ne ède dzesi dzesi siwo ɖea fu na wò—vevietɔ nya siwo ku ɖe wò nuɖuɖumeŋusẽ ŋu—la, taflatse di atikewɔla bibiwo ƒe aɖaŋuɖoɖo. Vitamin sue aɖe ƒe veve gɔ̃ hã ate ŋu akpɔ ŋusẽ ɖe wò lãmesẽ dzi vevie. Eyata lé fɔ ɖe nuɖuɖu si da sɔ ɖuɖu ŋu, lé agbenɔnɔ si me lãmesẽ le me ɖe asi, eye nàkpɔ ɖɔkta kaba ne lãmesẽkuxi aɖe le ŋuwò.
Pellagra, Niacin, Vitamin B3, Nunyiame ƒe Vevienyenye, Ŋutilã ƒe Nɔnɔmewo, Aɖuɖɔtoe, Tagbɔdɔ
