Ðewohĩ èse nya ' Stem Cells ' le afi aɖe kpɔ. Ðewohĩ le sinima aɖe me, le nyadzɔdzɔgbalẽ aɖe me, alo le internet dzi. Ame aɖewo gblɔna be esia ate ŋu ada dɔléle ɖesiaɖe. Ame bubuwo gblɔna be edzi ŋɔ vie. Eyata nuka tututue nye lãmenugbagbevi siawo? Ðe esia nye nane si atrɔ atikewɔwɔ ƒe etsɔme nyateƒea? Mina míaƒo nu tso eŋu pɛpɛpɛ, bɔbɔe ŋutɔ, egbea.
Kpuie ko la, nukawoe nye lãmenugbagbevi siawo?
Bu bɔl si wotsɔ anyi wɔe ŋu kpɔ. Míate ŋu atsɔ anyibolo ma awɔ nusianu, abe fefenuvi, ze, lã ene. Aleae lãmenugbagbeviwo le. Esiawoe nye ‘lãmenugbagbevi veviwo’ alo ‘lãmenugbagbevi veviwo’ le míaƒe ŋutilã me. Ŋutete wɔnuku eve le lãmenugbagbevi siawo si.
1. Lãmenugbagbevi geɖe wɔwɔ (Self-renewal): Lãmenugbagbevi ɖeka ate ŋu ama eye wòawɔ lãmenugbagbevi geɖe siwo nye ƒomevi ɖeka.
2. Vovototodedeameme: Esiae nye ŋutete si wɔ nuku wu. Lãmenugbagbevi siawo ate ŋu atrɔ azu lãmenugbagbevi tɔxɛ ɖesiaɖe si míaƒe ŋutilã hiã. Le kpɔɖeŋu me, woate ŋu azu ʋumenugbagbeviwo , ahɔhɔ̃menugbagbeviwo ( ahɔhɔ̃mekawo ), dzitodzito me lãmenugbagbeviwo, ŋutigbalẽmenugbagbeviwo , ƒumelãwo , kple bubuawo.
Ŋutete sia mele lãmenugbagbevi bubu aɖeke si le míaƒe ŋutilã me o. Esia tae ɖɔktawo kple dzɔdzɔmeŋutinunyalawo tsɔ ɖe le lãmenugbagbevi siawo me ale gbegbe ɖo.
Nukatae lãmenugbagbeviwo le vevie nenema gbegbe ɖo?
Dzɔdzɔmeŋutinunyalawo xɔe se be ŋutete si le lãmenugbagbevi siawo ŋu ate ŋu ana tɔtrɔ gã aɖe nava le atikewɔwɔ me le etsɔme. Susu vevi etɔ̃ tae wole vevie ɖo.
| Vevienyenye | Numeɖeɖe bɔbɔe |
|---|---|
| Dɔdamɔnu siwo wotu ɖe lãmenugbagbeviwo dzi | Tsɔe be dɔléle le ame ƒe dzi ƒe akpa aɖe ŋu. Aleke gbegbe wòaloloe nye si ne míate ŋu azã lãmenugbagbeviwo atsɔ awɔ dzitodzito me lãmenugbagbevi yeyewo eye míado wo ɖe akpa si ŋu dɔlélea le la me? Woyɔa esia be atikewɔwɔ si nana ame ƒe lãme gbugbɔna . Efia be woadzra lãmenugbagbevi alo ŋutinu siwo gblẽ ɖo alo agbugbɔ wo awɔ. |
| Alesi dɔlélewo dzɔnae gɔmesese | Ne míelé ŋku ɖe alesi lãmenugbagbevi aɖe tsina zua kansa lãmenugbagbevi alo lãmenugbagbevi bubu si ŋu dɔléle le ŋu le nudokpɔƒea la, míate ŋu ase alesi dɔléle mawo doa mo ɖa ŋutɔŋutɔ gɔme nyuie wu. Sidzedze sia akpe ɖe ame ŋu ŋutɔ le atikewɔmɔnu yeyewo didi me. |
| Atike yeyewo dodokpɔ | Hafi woatsɔ atike yeye aɖe ana amewo la, ehiã be woadoe kpɔ be ele dedie eye wòwɔa dɔ hã. Woate ŋu azã lãmenugbagbeviwo atsɔ adzi lãmenugbagbevi siwo do ƒome kple dɔléle (e.g., aklã me lãmenugbagbeviwo) le nudokpɔƒe, eye woate ŋu ado atike yeyea kpɔ le lãmenugbagbevi mawo dzi. Esia ate ŋu ana woase nu gɔme nyuie wu hafi adoe kpɔ le amewo ŋu. |
Nukawoe nye lãmenugbagbevi ƒomevi veviwo?
Lãmenugbagbevi ƒomevi eve koŋ ŋue míele nu ƒom tsoe.
1. Fugboe ƒe Lãmenugbagbeviwo
Esiawoe nye lãmenugbagbevi ‘siwo de ŋgɔ wu’ siwo ate ŋu awɔ nusianu. Abe alesi ŋkɔa ɖee fia ene la, wokpɔa wo tso fugboewo me. Etɔxɛe la, woxɔa wo hena numekuku tso fugboe siwo womezãna le vidzidzi le vitro ( IVF ) megbe o eye emegbe wozãa wo (ne dzilawo lɔ̃ ɖe edzi bliboe).
Ŋkɔ bubu si wotsɔ na lãmenugbagbevi siawoe nye ``pluripotent`` cells. Esia fia be woate ŋu ava zu lãmenugbagbevi ƒomevi ɖesiaɖe le ŋutilãa me. Le ŋutete sia si seɖoƒe meli na o ta la, ŋutete gã aɖe le wo si be woaɖɔ lãkusi siwo dɔléle gblẽ la ɖo. Gake esi wònye be fugboewo mee wokpɔa wo le ta la, agbenyuinɔnɔ ŋuti nyaʋiʋli aɖewo le xexeame ku ɖe esia ŋu.
2. Ame Tsitsiwo ƒe Lãmenugbagbeviwo
Togbɔ be wotsɔ ŋkɔ na lãmenugbagbevi siawo be "ame tsitsi" hã la, wole vidzĩwo, ɖeviwo, kple ame tsitsiwo katã ƒe ŋutilã me. Gake ŋusẽ mele wo ŋu abe fugboe ƒe lãmenugbagbeviwo ene o. Zi geɖe la, wokpɔa wo le agbɔsɔsɔ sue aɖe me le lãkusi vovovowo abe ƒumeŋuɖui, ŋutigbalẽ, ahɔhɔ̃, kple aklã ene me.
Zi geɖe la, lãmenugbagbevi siwo le ŋutigbalẽa me koŋ koe ame tsitsiwo wɔa lãmenugbagbeviwo le.Le kpɔɖeŋu me, lãmenugbagbevi si le ŋutigbalẽa me ate ŋu awɔ ŋutigbalẽmenugbagbevi yeyewo, gake menye dzitodzito me lãmenugbagbeviwo o.
Dzɔdzɔmeŋutinunya me ŋgɔyiyi yeyetɔ kekeake: iPS lãmenugbagbeviwo
Fifia dzɔdzɔmeŋutinunyalawo ke ɖe nu wɔnuku aɖe ŋu. Woate ŋu axɔ lãmenugbagbevi si le tsitsim abe míaƒe ŋutigbalẽ ene eye ‘woagbugbɔ awɔ ɖoɖo ɖe eŋu’ le nudokpɔƒe be wòawɔ nu abe fugboe ƒe lãmenugbagbevi ene. Woyɔa esiawo be induced pluripotent stem cells (iPS cells) . Esia ʋu mɔnukpɔkpɔ gã aɖe ɖi be woawɔ numekuku agbenyuinɔnɔ ŋuti nya siwo do ƒome kple fugboewo manɔmee.
Dɔdamɔnu kawoe wole zazãm fifia ɖe lãmenugbagbeviwo ŋu?
Esiae nye nusi ame geɖe dina be yewoanya. Le afisia la , ele be míase vovototo si le atike siwo wozãna fifia dzidzedzetɔe kple atike siwo wole mɔ kpɔm na le etsɔme dome gɔme nyuie .
Dɔdamɔnu siwo dzi woda asi ɖo fifia eye wozãa wo
Dɔlékuiwutike si bɔ wu eye wòkpɔa dzidzedze wu le xexeame egbeae nye lãmenugbagbeviwo dodo na ame si wɔa ʋu . Ðewohĩ èse esia be enye ‘ƒumeŋuɖui dodo na ame.’
Wozãa atikewɔwɔ sia koŋ na:
- Le ʋumenugbagbeviɣidɔ gome (e.g. Leukemia, Lymphoma) .
- Le ʋumenugbagbeviɣidɔ aɖewo gome (e.g. `Sickle cell anemia`) .
- Be woagbugbɔ ƒumeŋuɖui si wogblẽ to atikewɔmɔnuwo zazã me na kansa la atu
Le esia ta la, wokpɔa lãmenugbagbeviwo tso ame si le lãmesẽ me ƒe ƒumeŋuɖui me, alo tso vidzidɔ me ʋu me ne wodzi vi.
Etsɔme mɔkpɔkpɔwo kple numekuku ƒe ŋgɔyiyi
Dzɔdzɔmeŋutinunyalawo le mɔ kpɔm be woazã lãmenugbagbeviwo ƒe dɔdamɔnu dzidzedzetɔe na dɔléle bubu geɖewo le etsɔme. Ele vevie be míaɖo ŋku edzi be esiawo gakpɔtɔ le numekuku ƒe afɔɖeɖea me .
- Parkinson ƒe dɔlélea
- Alzheimer ƒe dɔlélea
- Suklidɔ
- Dzidɔ
- Abi siwo woxɔna le aklã me
- Ƒunukpeƒetetedɔ
Vevietɔ: Ne habɔbɔ aɖe gblɔ be "yeka ɖe lãmenugbagbeviwo ƒe atikewɔwɔ dzi" na dɔléle siawo la, bu eŋu zi eve. Womeda asi ɖe esiawo dzi haɖe be wonye atike siwo wozãna edziedzi o. Dzro nusianu me kple wò ɖɔkta.
Ðe atikewɔmɔnu siawo le dediea? Ðe afɔku aɖewo lia?
Abe atikewɔwɔmɔnu yeye ɖesiaɖe ene la, afɔku kple kuxiwo le lãmenugbagbeviwo ƒe dɔdamɔnu ŋu. Dzɔdzɔmeŋutinunyalawo nya nusiawo nyuie eye wole agbagba dzem be yewoakpɔ wo gbɔ.
- Afɔku si le kansa xɔxɔ me:Esi wònye be ŋutete le lãmenugbagbeviwo me be woama kabakaba ta la, woate ŋu ama ɣeaɖewoɣi le mɔ si dzi womate ŋu aɖu o nu eye wowɔa dɔdzẽ.
- Domenyiŋusẽfianu ƒe gbegblẽ: Ate ŋu adzɔ be lãmenugbagbevi siwo tsi le nudokpɔƒe ate ŋu agblẽ nu le domenyiŋusẽfianu aɖewo ŋu.
- Dɔlélenutsiŋutete ƒe gbegbe: Mía ŋutɔwo ƒe dɔlélenutsiŋutete ateŋu adze lãmenugbagbevi siwo wona mí tso ŋutilã godo dzi, awɔ nu ɖe wo ŋu abe ‘duta futɔwo’ ene.
- Afɔku siwo le atikewɔwɔmɔnua me: Afɔku siwo do ƒome kple amekoko ƒe mɔnuwo be woaxɔ lãmenugbagbeviwo alo ado wo ɖe lãme (e.g., atikewo dodo ɖe ahɔhɔ̃ me, dzi).
Wole numekuku wɔm be woaɖe afɔku siawo dzi akpɔtɔ. Eyata atikewɔwɔ mawo xɔxɔ tso teƒe siwo womeda asi ɖo o, siwo mesɔ o ate ŋu anye afɔku gã aɖe.
Gbedasi si Wotsɔ Yi Aƒeme
- Lãmenugbagbeviwo nye ‘lãmenugbagbevi gã’ ƒomevi tɔxɛ aɖe si ate ŋu ava zu lãmenugbagbevi ɖesiaɖe le ŋutilãa me. Ŋutete gã aɖe le wo si le atikewɔwɔ me.
- Fifia la, ʋumenugbagbeviɣidɔ abe ʋumenugbagbeviɣidɔ kple ʋumenugbagbeviɣidɔ aɖewo ene koe wozãna dzidzedzetɔe wu eye wozãnɛ le teƒe geɖe wu.
- Dɔlélewo abe suklidɔ, Parkinson, kple dzidɔ ene dada gakpɔtɔ le numekuku ƒe afɔɖeɖea me eye womeda asi ɖe edzi be woazã wo le afisiafi o.
- Hafi nàxɔ nusianu si nàkpɔ le internet dzi alo teƒe bubu aɖe tso lãmenugbagbeviwo ƒe atikewɔwɔ ŋu dzi se la, kpɔ egbɔ be yebia yeƒe ɖɔkta alo atikewɔla bibi aɖe tso eŋu.
- Kpɔ nyuie ŋutɔ le "lãmenugbagbeviwo ƒe dɔdaƒe" siwo dzi womeda asi ɖo o, siwo mele ɖoɖo nu o ŋu. Mègatsɔ wò lãmesẽ ade afɔku me o.
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