Ciwon ciki mai tsanani da kuma rashin sani ba tare da wani dalili ba... Bari mu koyi game da wannan cuta mai wuya? (Ciwon hanta mai tsanani)

Ka yi tunanin, ba tare da wani dalili ba, nan take za ka kamu da ciwon ciki mai tsanani. Tare da haka, gaɓoɓinka za su yi sanyi, za ka ji kamar za ka suma, kuma za ka ji tashin zuciya. Ko da bayan ganin likitoci da dama da kuma yin gwaje-gwaje da yawa, ba a gano ainihin dalilin rashin lafiyar ba. Shin kai ko wani da ka sani ya taɓa samun wannan matsalar? Wataƙila sanadin ita ce wata cuta ta kwayoyin halitta da ba kasafai ake samunta ba wadda mutane da yawa a ƙasarmu ba su ma ji labarinta ba. A yau za mu yi magana game da irin wannan matsalar, wato Acute Hepatic Porphyria , ko AHP.

A taƙaice dai, menene Acute Hepatic Porphyria (AHP)?

AHP wata cuta ce ta kwayoyin halitta da ba kasafai ake samunta ba wadda ke shafar tsarin jijiyoyinmu , wani lokacin kuma fatarmu. Yana da wuya sosai har yana shafar kusan mutane 5 cikin 100,000. Yana iya haifar da alamu na gaggawa, masu tsanani, masu zafi. Wani lokaci, waɗannan na iya zama barazana ga rayuwa.

Domin fahimtar wannan, bari mu yi ɗan bayani game da jinin da ke jikinmu. Kwayoyin jininmu ja suna ɗauke da wani furotin da ake kira " Hemoglobin ". Babban aikinsa shi ne ɗaukar iskar oxygen da ke shiga cikin huhu lokacin da muke numfashi sannan ya kai shi ga kowace gabobi da kyallen jiki. Kamar 'aikin isar da iskar oxygen' ne da ke ɗauke da iskar oxygen.

Akwai wani sinadari da ke da mahimmanci wajen samar da wannan furotin mai suna "Hemoglobin", kuma muna kiransa "Heme" .

Abin da ke faruwa a jikin mutumin da ke fama da cutar AHP shine raguwa ko asarar wani enzyme da ake buƙata a wani mataki yayin samar da wannan sinadarin da ake kira "Heme". Kamar lokacin dafa abinci ne, idan wani sinadari ya ɓace, ba za a iya shirya abincin yadda ya kamata ba.

Rashin wannan enzyme yana faruwa ne galibi a cikin hanta . Muna kuma kiran hanta da `(Hepatic)`. Shi ya sa aka sanya wa wannan cuta suna `Acute Hepatic Porphyria` .

To, me zai faru idan ba za mu iya yin `(Heme)` ba? Kayan da aka yi amfani da su wajen yin sa, wato `(Porphobilinogen – PBG)` da `(Aminolevulinic acid – ALA)`, suna fara taruwa a cikin hanta. Waɗannan gubobi suna taruwa a cikin jini kuma suna yawo a cikin jiki, musamman suna lalata tsarin jijiyoyinmu. Saboda lalacewar jijiyoyi ne alamun kamar zafi mai tsanani , suma , da tashin zuciya ke tasowa.

Waɗanne manyan nau'ikan cututtukan AHP ne?

Akwai manyan nau'ikan AHP guda huɗu. Kowanne nau'in yana faruwa ne sakamakon rashin wani enzyme daban yayin samar da "(Heme)" a cikin jiki. Amma dukkansu huɗun galibi suna shafar hanta da tsarin jijiyoyi.

Ciwon Porphyria Mai Tsanani (AIP)

Wannan nau'in shine wanda ke shafar kashi 80% na marasa lafiya na AHP, wato, mafi yawansu. A cikin wannan, akwai ƙarancin enzyme `(Hydroxymethylbilane synthase – HMBS)`. Dalilin wannan shine canji a cikin kwayar halittar `(HMBS)`. A magani, muna kiran wannan kwayar halittar `(maye gurbi)` . Wannan wani lokacin ana iya gado shi daga iyaye zuwa yara. Ko kuma wani lokacin yana iya faruwa bazuwar a cikin mutum ba tare da tarihin iyali ba.

Yaya alamun AHP suke ji?

Ba duk wanda ke da AHP yake da irin wannan alamun ba. Wasu mutane ba za su iya samun wata alama ba kwata-kwata a rayuwarsu. Amma wasu mutane na iya samun hare-hare masu tsanani akai-akai. Yana da mahimmanci a gane waɗannan alamun.

Wadanne abubuwa ne ke haifar da ta'azzara cutar?

Mutumin da ke da AHP zai iya rayuwa kamar yadda aka saba. Duk da haka, wasu abubuwa na iya haifar da cutar. Yana da matuƙar muhimmanci a san da waɗannan.

• Wasu magunguna: Musamman wasu magunguna kamar maganin rigakafi da ke ɗauke da `(Barbiturates)` da `(Sulfa)`. Idan kana da AHP, yana da mahimmanci ka yi magana da likitanka kafin ka sha wani magani.
• Shan barasa: Barasa ita ce babbar hanyar da ke ƙara ta'azzara wannan cuta.
• Tsananin cin abinci ko azumi: Cin abinci mai ƙarancin kalori da carbohydrates (sitaci) na iya ƙara ta'azzara cutar.
• Canjin Hormonal: Canje-canje a matakan hormones, musamman a cikin mata, waɗanda ke da alaƙa da zagayowar jinin al'ada.
• Damuwa da Cututtukan da ke Yaduwa: Duk wani nau'in damuwa a jiki, har ma da yanayin kamuwa da cuta kamar zazzabi ko mura, na iya ƙara ta'azzara cutar.

Yaushe ya kamata ka ga likita?

Idan kana da waɗannan alamomin, don Allah kar ka yi watsi da su kamar yadda aka saba. Yana da matuƙar muhimmanci a nemi shawarar likita, musamman a waɗannan yanayi:

• Idan kana da ciwon ciki mai tsanani wanda ba a bayyana ba, wanda ke sake faruwa.
• Idan alamun jijiyoyi kamar suma da rauni suka faru a lokaci guda.
• Idan ka san cewa wani a cikin iyalinka yana da cutar `(Porphyria)`.
• Idan ka lura cewa fitsarinka yana canza launin ja/kasa mai duhu.

Idan ka fuskanci manyan alamu, kamar ciwo mai tsanani, wahalar numfashi, ruɗani a kwakwalwa, ko asarar gaɓoɓi, ka je sashin kula da gaggawa na asibiti (ETU) nan da nan.

Akwai magani ga AHP?

Tunda wannan cuta ce ta kwayoyin halitta, babu magani tukuna. Duk da haka, akwai magunguna masu inganci don magancewa da hana ta'azzara cutar.

A cikin mawuyacin hali, ana buƙatar a kwantar da shi a asibiti da kuma magani.

• Babban abu shine a gano abin da ke haifar da cutar da kuma dakatar da ita.
• Ana ba da magungunan rage radadi masu ƙarfi don magance radadi mai tsanani.
• Ana ba da magunguna don magance tashin zuciya da amai.
• Ta hanyar ba wa jiki glucose (sukari), wato, glucose tare da saline ta hanyar jijiya, ana iya rage samar da guba a cikin hanta.
• A matsayin wani takamaiman magani , ana yin allurar `(Heme)` `(Hemin infusions)`. Ana yin wannan ta hanyar ba da `(Heme)` a waje, aika sigina zuwa hanta yana cewa, "Kuna da `(Heme)`, ba kwa buƙatar yin wani abu," da kuma dakatar da samar da guba.
• Baya ga wannan, yanzu akwai magungunan zamani da ake samarwa ta hanyar fasahar kwayoyin halitta don hana sake kamuwa da cutar ga waɗanda ke fama da tashe-tashen hankula akai-akai.

Likitan da zai duba ka zai tantance mafi dacewa da kai.

AHP, Porphyria mai tsanani a hanta, Porphyria, Ciwon ciki, Cututtukan jijiyoyi, Cututtukan gado, Heme, Hemoglobin, Porphyrin, Cututtuka masu wuya