Ua loli anei ka waiwai ALP i loko o kāu hōʻike koko? (Hoʻāʻo Alkaline Phosphatase) E ʻike kākou i ke ʻano o kēia!

Ua loaʻa anei iā ʻoe kahi hoʻāʻo koko i hala koke aku nei? Ke ʻike ʻoe i ka waiwai ALP ma waena o nā leka a me nā helu, ua manaʻo paha ʻoe, 'He aha kēia?' Mai hopohopo, ua like ka manaʻo o ka poʻe he nui. He mea maʻamau ia. I kēia lā, e kamaʻilio kākou e pili ana i ke ʻano o kēia hoʻāʻo ALP, no ke aha e nānā ai nā kauka, a me nā loli o kona mau waiwai e ʻōlelo maoli ai e pili ana i ko kākou olakino.

ʻO ka mea mua, e nānā kākou, he aha ka alkaline phosphatase (ALP)?

I ka ʻōlelo maʻalahi, ʻo ka alkaline phosphatase, a i ʻole ALP e like me kā mākou e kamaʻilio nei, he enzyme ia i loko o ko mākou kino. Ua like ia me kahi mea hana liʻiliʻi i loko o ko mākou kino. Loaʻa nui kēia mea hana i loko o ko mākou akepaʻa a me nā iwi . Eia kekahi, loaʻa nā liʻiliʻi liʻiliʻi i loko o kā mākou ʻōnaehana hoʻoheheʻe, nā puʻupaʻa, a me ka placenta i ka wā hāpai.

ʻOiai ʻaʻole i maopopo loa i nā kānaka ʻepekema, ua manaʻoʻiʻo ʻia he nui nā hana koʻikoʻi a kēia enzyme ALP i loko o ko kākou kino. No ka laʻana, kōkua ʻo ALP i ke kūkulu ʻana i nā ʻiʻo ikaika e like me nā iwi a me nā niho, a kōkua i ka hoʻoneʻe ʻana i nā mea e like me ka phosphate a puni i loko o nā ʻōpū.

ʻO ka pilina ma waena o ke akepaʻa momona a me ka ALP

ʻO ALP kekahi māka i hoʻohana ʻia no ka ʻike ʻana i ka maʻi akepaʻa momona. Eia naʻe, ʻaʻole ia wale nō ka māka e hiki ke ʻike i ke kūlana. ʻElua ʻano nui o ka maʻi akepaʻa momona:

• ʻO ka maʻi ate steatotic e pili ana i ka metabolic (MASLD): Hoʻokumu ʻia kēia e ka hōʻiliʻili ʻana o ka momona i loko o ke akepaʻa ma muli o nā mea e like me ke cholesterol kiʻekiʻe, ka maʻi diabetes type 2, ke kūʻē ʻana o ka insulin, a i ʻole kahi helu helu kino (BMI) ʻoi aku ma mua o 30.
• ʻO ka maʻi ʻona momona o ke akepaʻa: E like me ka inoa e hōʻike nei, ʻo kēia ke kumu o ka inu nui ʻana i ka waiʻona i kahi manawa lōʻihi.

E ke kauka, no ke aha ʻoe e noi mai nei iaʻu e hana i kahi hoʻokolohua ALP?

Aia kekahi mau kumu e kauoha ai kāu kauka i kahi hoʻāʻo ALP. ʻO ka hapa pinepine, hana ʻia kēia e hōʻoia inā he hōʻino kou akepaʻa a i ʻole he maʻi iwi.

I kekahi manawa, hoʻokomo ʻia kēia hoʻāʻo ALP ma ke ʻano he ʻāpana o ka "comprehensive metabolic panel (CMP)" a mākou e hana mau ai i ka wā o ka "hoʻokolokolo olakino makahiki", a i ʻole ma ke ʻano he ʻāpana o ka "atmeal panel" e nānā i ka hana o ke ake.

Inā ʻoe e lawe mau ana i nā lāʻau lapaʻau e hiki ke hoʻopilikia i ke ake (e like me ka paracetamol, nā statins e hoʻohaʻahaʻa ana i ka cholesterol), hiki i kāu kauka ke hana pinepine i kahi hoʻāʻo ALP e nānā inā e hoʻopilikia ana kēlā mau lāʻau lapaʻau i kou ake.

Ke hiki mai ka hōʻike... Pehea ʻoe e hoʻomaopopo ai i nā waiwai ALP?

ʻO ka maʻamau, loaʻa ka hōʻike i loko o hoʻokahi a ʻelua paha lā. Hiki ke ʻokoʻa iki ka pae maʻamau no ALP mai kekahi keʻena hoʻokolohua a i kekahi. ʻO ka maʻamau, aia kēia waiwai ma waena o 44-147 IU/L (nā ʻāpana honua no ka lita). E hōʻike pū kāu hōʻike i ko lākou pae maʻamau.

Inā kiʻekiʻe ka waiwai ALP ...

ʻAʻole he hōʻailona o kahi maʻi koʻikoʻi ka pae ALP kiʻekiʻe iki ma mua o ka maʻamau. Hiki ke hoʻokiʻekiʻe ʻia nā pae ALP ma muli o kekahi mau kumu maʻamau a kūlohelohe .

• Ke ulu nei nā keiki a me nā ʻōpio: Ma muli o ka ulu wikiwiki ʻana o ko lākou mau iwi, kiʻekiʻe maoli nā pae ALP.
• Hāpai: I ka wā hāpai, hiki i ka ALP ke hoʻonui a hiki i ʻekolu manawa o ka waiwai maʻamau no ka mea ʻo ka placenta ka mea e hana ai.
• Ka ʻelemakule: Hiki ke hoʻonui iki ʻia nā pae ALP i kou wā ʻelemakule.
• Ke ho'ōla ʻia kahi iwi haki: Ke haki kahi iwi, hoʻonui ʻia ka ALP no kekahi manawa i kona ho'ōla ʻana.
• ʻAi ʻana i kahi meaʻai momona kiʻekiʻe ma mua o ka hoʻāʻo ʻana: No kekahi poʻe, ʻo ka ʻai ʻana i kahi meaʻai momona kiʻekiʻe ma mua o ka hoʻāʻo ʻana hiki ke hoʻonui i nā pae ALP.
• Puhi paka.

Eia nō naʻe, hiki i kekahi mau kūlana olakino ke hoʻonui nui i nā pae ALP.

Inā haʻahaʻa ka waiwai ALP...

He mea kākaʻikahi loa ka ʻike ʻana i ka emi ʻana o nā pae ALP ma mua o ka piʻi ʻana. ʻO nā kumu paha:

• ʻAʻohe pono o nā minelala e like me ka zinc a i ʻole ka magnesium.
• Ka emi ʻana o ka hana o ka thyroid gland (Hypothyroidism).
• He maʻi laha ʻole ka Hypophosphatasia (HPP).
• Ka maʻi o Wilson.
• ʻO kekahi mau lāʻau lapaʻau (e like me nā pila hoʻomalu hānau).

He aha nā hōʻailona o kahi loli i nā pae ALP a me ka mea e hana ai ma hope?

I ka hapanui o nā hihia, ʻaʻohe hōʻailona kikoʻī o kahi pae ALP i hoʻololi ʻia. Eia nō naʻe, hiki ke ʻike ʻia nā hōʻailona ma muli o ke kūlana olakino kumu e hoʻokumu ai.

| Nā hōʻailona e pili ana i ke akepaʻa | Nā hōʻailona e pili ana i ka iwi |

| :--- | :--- |

| Melemele o nā maka a me ka ʻili (jaundice) | ʻEha i nā iwi a me nā hono |

| Mimi ʻeleʻele a me nā ʻōpala māmā | Māmā ka haki ʻana o ka iwi |

| ʻĀnai | Pehu a me ka mumū o nā hono |

| Ka luaʻi a me ka luaʻi | Ka ʻino o ka iwi |

| Ka nalowale o ka makemake e ʻai a me ka luhi loa | |

ʻEha ka ʻōpū a i ʻole ka pehu ʻana

He aha ka mea e hana ai ma hope?

Inā ʻokoʻa kāu pae ALP, e kauoha kāu kauka i kekahi mau hoʻokolohua hou aʻe e hoʻoholo i ke kumu pololei.

1. Ke hana hou ʻana i ka hoʻāʻo: Hiki ke noi ʻia ʻoe e hoʻokē ʻai no 10-12 mau hola a laila e hana hou i ka hoʻāʻo.

2. Hoʻāʻo isoenzyme ALP: Hiki i kēia ke hoʻokaʻawale pololei inā no ke akepaʻa a i ʻole mai nā iwi mai ka ALP i hoʻonui ʻia.

3. Hoʻāʻo GGT: ʻO ka 'Gamma-glutamyl transpeptidase (GGT)' kahi enzyme i ʻoi aku ka kikoʻī i ke akepaʻa. Inā hoʻokiʻekiʻe ʻia ʻo GGT me ALP, ʻoi aku ka nui o ka pilikia ma ke akepaʻa.

4. Nā hoʻokolohua ʻē aʻe: Eia kekahi, hiki ke hana ʻia nā haʻawina kiʻi a i ʻole, inā pono, kahi biopsy e wehe i kahi ʻāpana liʻiliʻi o ka ʻiʻo mai ke akepaʻa.

Ke hoʻomākaukau ʻana no ka hoʻāʻo a me kāna kaʻina hana

He mea maʻalahi loa kēia a hiki ke hoʻopau ʻia i loko o kekahi mau minuke.

• Hoʻomākaukau: E aʻo aku paha kāu kauka iā ʻoe ʻaʻole e ʻai a inu paha i kekahi mea koe wale nō ka wai no 10-12 mau hola ma mua o ka hoʻāʻo. He mea nui e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āpau, nā huaora, a me nā mea hoʻohui āu e lawe nei. He mea nui hoʻi e haʻi i kāu kauka inā hāpai ʻoe.
• Kaʻina Hana:Ma ke keʻena hoʻokolohua, loaʻa iā lākou kahi aʻa koko ma kou lima, hoʻomaʻemaʻe i ka wahi, hana i kahi puka liʻiliʻi, a lawe wale i kahi koko liʻiliʻi. Manaʻo ia e like me kahi puka liʻiliʻi, akā ʻaʻole ʻeha loa. A laila kau lākou i kahi palaki liʻiliʻi ma ka wahi. ʻO ia wale nō.