Loaʻa paha iā ʻoe kekahi lālā o ka ʻohana, he hoaaloha, a i ʻole ʻoe iho e mālama ʻia ana no ka maʻi ʻaʻai umauma . I nā manawa e like me kēia, paipai nā kauka i nā lāʻau lapaʻau like ʻole. I waena o lākou, ʻo kahi mea a ka poʻe e lohe pinepine ai, ʻoiai no ka maʻi ʻaʻai umauma e kū mai ana ma hope o ka menopause, ʻo Exemestane. Ua ʻike paha ʻoe iā ia ma ka inoa inoa ʻo Aromasin. I kēia lā, e kamaʻilio wale mākou e pili ana i kēia lāʻau lapaʻau, kāna hana, pehea ka maikaʻi o ia mea, a me nā mea e makaʻala ai i ka wā e hoʻohana ai.
Pehea e hōʻemi ai ka exemestane i ka ulu ʻana o nā hunaola kanesa o ka umauma?
I ka ʻōlelo maʻalahi, aia kekahi mau ʻano maʻi ʻaʻai umauma i kōkua ʻia e ulu e ka hormone estrogen i loko o ko mākou kino. ʻO kēia ka mea a mākou e kapa nei he mau maʻi ʻaʻai 'hormone-receptor-positive'. E noʻonoʻo i nā hunaola maʻi ʻaʻai e like me kahi mea kanu e ʻai ana i ka 'meaʻai' i kapa ʻia ʻo estrogen.
Hana ʻo Exemestane ma ke kāohi ʻana i ka hana ʻana o ka hormone estrogen i loko o ko kākou kino. Ua like ia me ke kāohi ʻana i ka meaʻai i hānai ʻia i ka mea kanu. A laila nalowale nā meaʻai e pono ai nā hunaola kanesa. Ma kēia ʻano, kōkua nui kēia lāʻau lapaʻau i ka pale ʻana i ka hoʻi hou ʻana mai o ke kanesa.
Ua hōʻoia ʻia kēia e ka noiʻi. Ma kahi noiʻi 3 makahiki, ua hāʻawi ʻia ka exemestane i nā wahine i loaʻa i ka maʻi ʻaʻai umauma invasive ma hope o ka menopause, a ua hoʻemi ʻia ko lākou pilikia o ka hoʻi hou ʻana mai o ke kanesa ma ka 65% i hoʻohālikelike ʻia me nā wahine i loaʻa ʻole. Eia kekahi, koe wale nō nā hōʻailona maʻamau o ka menopause, e like me nā ʻālohilohi wela, ʻaʻohe hopena ʻaoʻao koʻikoʻi i hōʻike ʻia.
Hiki ke hoʻohana ʻia me nā lāʻau lapaʻau ʻē aʻe?
ʻAe, ʻoiaʻiʻo nō. ʻAʻole i kaupalena ʻia ka lāʻau lapaʻau maʻi kanesa i hoʻokahi wale nō lāʻau. I kekahi manawa pono e kuhikuhi i nā ala like ʻole e pepehi i nā hunaola kanesa. ʻO ia ke kumu e hoʻolālā ai nā kauka i ka lāʻau lapaʻau ma ka hoʻohui ʻana i kekahi mau lāʻau.
Ua hōʻike ʻia e ka noiʻi hiki ke hāʻawi ʻia ka lāʻau exemestane me nā lāʻau ʻē aʻe e like me ka ribociclib a me ka everolimus (i ʻike ʻia hoʻi ʻo 'triplet therapy'). Hoʻemi kēia hui pū ʻana o nā lāʻau i nā manawa kūpono o ke ola ʻana o nā hunaola kanesa a hoʻemi hou i ka pilikia o ka hoʻi hou ʻana mai o ke kanesa. Ua ʻike ʻia hoʻi he palekana loa kēia lāʻau lapaʻau.
Ma kahi noiʻi hou nei, he maʻi maʻi ʻaʻai umauma 48 makahiki i hana ʻia i ka chemotherapy) Ma hope mai, ua hāʻawi pū ʻia ʻelua mau lāʻau i kapa ʻia ʻo Exemestane lāua ʻo everolimus. Ua hana pū kēia mau lāʻau ʻelua e luku i nā hunaola kanesa a pale i ka hoʻi hou ʻana mai o ke kanesa. I ka nānā ʻia ʻana o ka mea maʻi no 5 mau makahiki, ʻaʻohe ulu ʻana o ke kanesa i loko o kona kino. Hōʻike kēia i ka holomua o kēia lāʻau.
Nā mea e pono ai ʻoe e ʻike e pili ana iā Exemestane
| ʻoiaʻiʻo | Wehewehena |
|---|---|
| Hoʻohana nui | I mea e pale ai i ka hoʻi hou ʻana o ka maʻi ʻaʻai umauma hormone-receptor-positive ma hope o ka menopause. |
| Hana | Hoʻopili ia i ka hana ʻana o ka hormone estrogen i loko o ke kino a hoʻōki i ka ulu ʻana o nā hunaola maʻi kanesa. |
| Nā hopena ʻaoʻao maʻamau | ʻO nā hōʻailona maʻamau o ka menopause e komo pū me nā ʻā wela, nā ʻeha hui, a me ka luhi. |
| ʻO wai ka mea kūpono ʻole? | ʻAʻole kūpono no nā wahine premenopausal, nā wahine hāpai a i ʻole e hoʻāʻo nei e hāpai, a me nā makuahine hānai. |
Nā Manaʻo Kūikawā i ka wā e lawe ai i kēia lāʻau lapaʻau
Aia kekahi mau mea āu e makaʻala ai i ka wā e hoʻohana ai i kēia lāʻau lapaʻau. He mea nui loa kēia mau mea.
E hoʻomanaʻo, he hana hui ka mālama ʻana i ka maʻi kanesa ma waena ou a me kāu kauka, no laila ʻoi aku ka maikaʻi o ka wehe ʻana i nā mea āpau.
- E hahai pono i nā ʻōlelo a ke kauka: No kāu kēia lāʻau lapaʻauHe mea nui loa ka lawe ʻana i ka lāʻau lapaʻau e like me ka ʻōlelo a kāu kauka , ma ke ana kūpono, i ka manawa kūpono. Mai hoʻololi i ka ana a i ʻole e hoʻōki i ka lawe ʻana i ka lāʻau lapaʻau iā ʻoe iho. Inā he mau hopohopo kāu, e kamaʻilio me kāu kauka e pili ana i ia mea.
- Nā pilikia inā ʻoe ma mua o ka menopause: ʻAʻole hāʻawi pinepine ʻia kēia lāʻau lapaʻau i nā wahine ma mua o ka menopause no ka mea hiki ke hoʻopilikia i ka hānau keiki. E kūkākūkā hou aku kāu kauka i kēia me ʻoe.
- Mai hoʻohana i ka wā hāpai: Mai hoʻohana i kēia lāʻau lapaʻau inā hāpai ʻoe, e hoʻāʻo ana e hāpai, a hānai waiū paha. Pono ʻoe e pale i ka hāpai ʻana i ka wā e lawe ana i ka lāʻau lapaʻau. E kūkākūkā me kāu kauka no ka ʻōlelo aʻo no kēia.
- E makaʻala me nā lāʻau lapaʻau ʻē aʻe: Mai lawe i nā lāʻau lapaʻau ʻē aʻe i loaʻa ka estrogen (no ka laʻana, ka lāʻau hoʻololi hormone ) me Exemestane. Hana kūʻē kēia mau lāʻau lapaʻau ʻelua kekahi i kekahi, hiki ke hana i nā hopena ʻaoʻao. Inā ʻoe e lawe ana i nā lāʻau lapaʻau ʻē aʻe, nā huaora, a i ʻole nā lāʻau lapaʻau lāʻau, e haʻi i kāu kauka e pili ana iā lākou.
Leka Lawe-Home
- He lāʻau lapaʻau kūpono ʻo Exemestane no ka pale ʻana i ka hoʻi hou ʻana o ka maʻi ʻaʻai umauma hormone-receptor-positive e kū mai ana ma hope o ka menopause.
- Hana kēia ma ke kāohi ʻana i ka hana ʻana o ke kino i ka hormone estrogen a me ke kāohi ʻana i ka ulu ʻana o nā hunaola kanesa.
- Hiki ke hoʻokō ʻia nā hopena maikaʻi aʻe ma ka hoʻohana ʻana i kēia lāʻau lapaʻau me nā lāʻau anticancer ʻē aʻe.
- ʻAʻole pono e hoʻomaka a hoʻōki paha kēia lāʻau lapaʻau me ka ʻole o ke aʻo ʻana a ke kauka.
- Inā he mau nīnau a hopohopo paha kāu e pili ana i kēia lāʻau lapaʻau a i ʻole ka lāʻau lapaʻau, e kamaʻilio ākea me kāu kauka e pili ana. Mai makaʻu.
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