ʻO ka ʻōnaehana pale o kou kino, ka ʻōnaehana pale e pale aku iā ʻoe mai ka maʻi, i kekahi manawa ke hoʻomaka hewa nei e hoʻouka i kāu mau hunaola olakino ponoʻī. Ua kapa ʻia kēia maʻi he maʻi autoimmune. ʻO ka poʻe wale nō i loaʻa iā ia ka ʻike i ka paʻakikī o ke ola ʻana me ka ʻeha hui, ka pehu ʻana, a me ka ʻoʻoleʻa e hana ai. No laila, ua kuhikuhi anei kāu kauka iā ʻoe i kahi ʻano lāʻau i kapa ʻia ʻo DMARDs? A ua lohe paha ʻoe iā lākou? I kēia lā, e kamaʻilio kākou e pili ana i ke ʻano o kēia mau DMARDs, pehea lākou e hana ai, a me nā mea āu e pono ai e ʻike e pili ana iā lākou.
He aha nā DMARD? I ka pōkole...
ʻO DMARDs ke kū nei no Disease-Modifying Antirheumatic Drugs . ʻOiai ke kani paʻakikī iki nei ka inoa, he maʻalahi loa ka hana. He mau lāʻau lapaʻau kūikawā kēia e pale aku i kāu ʻōnaehana pale mai ka lilo ʻana i mea hana nui a hōʻino i kou kino ponoʻī.
E noʻonoʻo i kāu ʻōnaehana pale ma ke ʻano he pūʻali koa e pale aku ana i kahi ʻāina. ʻO ka maʻamau, hoʻouka wale kēia pūʻali koa i nā ʻenemi haole (nā germs). Akā i loko o kahi maʻi autoimmune, hele hewa kēia pūʻali koa a hoʻouka i nā poʻe hala ʻole ma kona ʻāina ponoʻī (nā ʻiʻo olakino i loko o ke kino). ʻO ka mea a DMARD e hana ai, ʻo ia ka hoʻomālielie ʻana i kēia pūʻali koa hana nui a hoʻihoʻi iā ia e hana pono.
ʻO nā pono nui āu e loaʻa ai mai kēia lāʻau lapaʻau:
- Hoʻemi ia i ka mumū i loko o ke kino, ʻo ia hoʻi ka pehu, ka ʻulaʻula, a me ka ʻeha.
- Hoʻomaha i ka ʻeha.
- Hoʻolohi i ka laha ʻana a i ʻole ke koʻikoʻi o ka maʻi.
- Hoʻēmi a pale paha i ka hōʻino ʻana i kou mau iwi a me nā hono i hoʻokumu ʻia e ka maʻi.
- Kōkua i ka mālama ʻana i ka hana maikaʻi o nā hono.
He aha nā maʻi e hoʻohana ʻia ai nā DMARD?
Hoʻohana nui nā kauka i nā DMARD e kāohi i nā ʻano maʻi autoimmune like ʻole e hoʻoulu ai i ka mumū. Ua lohe paha ʻoe i kekahi o kēia mau mea.
| Inoa o ka maʻi (Kūlana) | He hoʻolauna pōkole |
|---|---|
| ʻO ka ʻāʻī rheumatoid | He kūlana maʻamau e hoʻoulu ai i ka ʻeha, ka pehu, a me ka ʻoʻoleʻa o nā hono. |
| ʻO ka Spondylitis Ankylosing | He ʻano maʻi ʻāʻī e hoʻopilikia nui ana i ka iwi kuamoʻo. |
| ʻO ka maʻi ʻeha Psoriatic | ʻO ka Psoriasis kahi ʻano arthritis e kū mai ana i kekahi poʻe me ka psoriasis. |
| Lupus | He maʻi e hiki ke hoʻopili i nā ʻōkana like ʻole e like me ka ʻili, nā hono, nā puʻupaʻa, a me ka lolo. |
| ʻO ka ʻāʻī Idiopathic ʻōpio | ʻO ka Arthritis i nā keiki ma lalo o 16 makahiki. |
| ʻO ka ʻeha koko | He maʻi nona ke ʻano nui ka paʻakikī a me ka mānoanoa o ka ʻili. |
| Sclerosis lehulehu | He maʻi o ka ʻōnaehana nerve e hoʻopilikia ai i ka lolo a me ke kaula kuamoʻo. |
Eia kekahi, ʻaʻole hoʻohana pinepine ʻia nā DMARD no kekahi ʻano maʻi kanesa a no ka uveitis, kahi maʻi mumū o ka maka i pane ʻole i nā lāʻau ʻē aʻe.
He aha nā ʻano DMARD i loaʻa?
Hiki ke hoʻokaʻawale ʻia nā DMARD i ʻelua mau ʻāpana nui.
1. Nā DMARD Kuʻuna
ʻO kēia nā ʻano DMARD mua i ʻike ʻia. Hana kēia mau lāʻau lapaʻau ma ka hōʻoluʻolu ʻana i ka ʻōnaehana pale holoʻokoʻa . No ka mea he kakaikahi ko lākou mau hopena ʻaoʻao, e kuhikuhi mua paha kāu kauka i kēia ʻano lāʻau lapaʻau. Lawe pinepine ʻia kēia mau mea ma ke ʻano he pila.
ʻO kekahi mau laʻana:
- ʻAzathioprine
- ʻO ka Hydroxychloroquine
- ʻO ka Leflunomide
- ʻO ka Methotrexate
- ʻO ka Sulfasalazine
2. Nā DMARD Olaola (Biologics)
He mau lāʻau lapaʻau hou kēia a holomua. Ua like lākou me nā snipers. ʻAʻole lākou e hoʻopilikia i ka ʻōnaehana pale holoʻokoʻa e like me nā DMARD kuʻuna.Hoʻopaʻa a hoʻouka wale lākou i nā pūnaewele pale kino kikoʻī e hoʻoulu ai i ka pilikia.
ʻOi aku ka ikaika o kēia mau mea a ʻoi aku ka maikaʻi ma mua o nā DMARD kuʻuna. Eia nō naʻe, loaʻa iā lākou kahi pilikia kiʻekiʻe iki o nā hopena ʻaoʻao. Inā ʻaʻole ʻoe e hoʻomaikaʻi me nā lāʻau lapaʻau kuʻuna, hiki i kāu kauka ke hoʻoholo e hoʻomaka iā ʻoe ma kēia ʻano lāʻau lapaʻau ma ke ʻano he hana aʻe.
Hāʻawi pinepine ʻia kēia mau mea ma ke ʻano he infusion intravenous (IV), a i ʻole ma ke ʻano he injection subcutaneous. Inā pono ʻoe e hoʻohana i kēlā ʻano injection, e aʻo aku kāu kauka a kahu maʻi paha iā ʻoe pehea e hāʻawi palekana a pololei.
Loaʻa iā DMARDs nā hopena ʻaoʻao?
E like me nā lāʻau lapaʻau āpau, hiki i nā DMARD ke hana i kekahi mau hopena ʻaoʻao. Eia naʻe, ʻaʻole loaʻa i nā kānaka a pau. Hiki ke ʻokoʻa kēia ma muli o ke ʻano o ka lāʻau lapaʻau āu e loaʻa ai.
Mea nui: Mai hopohopo i ka heluhelu ʻana e pili ana i kēia mau hopena ʻaoʻao. E kaupaona pono kāu kauka i nā pilikia a me nā pono ma mua o ke kau ʻana i kēia lāʻau. E aʻo pū ʻo ia iā ʻoe pehea e hoʻokele ai i nā pilikia e kū mai ana.
| ʻAno o ka hopena ʻaoʻao | Nā hōʻailona hiki ke loaʻa |
|---|---|
| Nā hopena ʻaoʻao maʻamau i nā ʻano lāʻau ʻelua | |
| Hoʻonui ʻia ka pilikia o ka maʻi | Ma muli o ka hoʻemi ʻana i ka palekana, hiki ke ulu maʻalahi nā maʻi e like me ke anu a me ka maʻi palū (ʻoi aku ke kiʻekiʻe o kēia pilikia me nā biologics). |
| Nā hunaola koko i hoʻemi ʻia | Hiki paha ke emi iho nā keʻokeʻo koko (leukopenia), nā keʻokeʻo koko ʻulaʻula (anemia), a i ʻole nā platelets (thrombocytopenia). |
| Nā enzymes akepaʻa kiʻekiʻe | Hiki ke ʻike ʻia kēia ma o nā hoʻāʻo koko. |
| Nā hopena ʻaoʻao e pili ana i nā DMARD kuʻuna | |
| Nā pilikia o ka ʻōnaehana hoʻoheheʻe | Ka nalowale ʻana o ka makemake, ka nausea, ka luaʻi ʻana, ka ʻeha o ka ʻōpū, ka maʻi pākī. |
| Nā pilikia ʻili | ʻŌhūhū ʻili. |
| Nā hopena ʻaoʻao e pili ana i nā biologics | |
| Ka puka ʻana mai o nā maʻi huna | Hiki i nā maʻi e like me ka maʻi puʻupuʻu a me ka herpes, ka mea i hiamoe i loko o ke kino ma hope o ka ho'ōla ʻia ʻana ma mua, ke ala hou mai. |
| ʻĒ aʻe | Hoʻonui ʻia ka pae cholesterol, hoʻonui ʻia ka pilikia o nā ʻūpā koko, ʻulaʻula a pehu paha ma kahi i inikini ʻia. |
Pehea ka wikiwiki o ka hoʻomaka ʻana o kēia lāʻau lapaʻau e hana?
Eia kahi pilikia i loaʻa i nā poʻe he nui. ʻAʻole nā DMARD he ʻano lāʻau lapaʻau āu e lawe wale ai a manaʻo maikaʻi, e like me ka lāʻau ʻeha. Hiki i kēia mau lāʻau lapaʻau ke lōʻihi mai kekahi mau pule a i hoʻokahi mahina a ʻoi aku paha e hōʻoluʻolu i ka ʻōnaehana pale a kāohi i nā hōʻailona.
No laila, mai ho'ōki i ka lawe ʻana i ka lāʻau lapaʻau no ka mea ʻaʻole ʻoe e ʻike i ka ʻokoʻa nui i nā pule mua. He mea nui loa ia e hoʻomanawanui a hoʻomau i ka hoʻohana ʻana i ka lāʻau lapaʻau e like me ka ʻōlelo a kāu kauka.
Āhea ʻoe e pono ai e ʻike hou i kāu kauka?
Ma hope o kou hoʻomaka ʻana i nā DMARD, pono kāu kauka e ʻike iā ʻoe i nā manawa maʻamau e nānā inā e hana ana ka lāʻau lapaʻau a inā he mau hopena ʻaoʻao. Pono paha ʻoe e hana i kekahi mau hoʻokolohua i kēia manawa.
- Nā hoʻāʻo koko: E nānā inā e hana ana ka lāʻau lapaʻau, inā ua hoʻopilikia ʻia ke akepaʻa, a inā maʻamau nā pae o nā sela koko.
- E hoʻāʻo no nā maʻi: E nānā no nā maʻi huna, ʻoiai inā ʻoe e lawe ana i nā biologics.
- Nā hoʻokolohua kiʻi e like me nā kukuna X: E ʻike pehea e loli ai ka pōʻino o nā hono i ka hala ʻana o ka manawa.
Inā ʻike ʻoe i kekahi mau hopena ʻaoʻao hou, inā e ʻoi aku ka ʻino o kāu mau hōʻailona, a inā ʻaʻole like ka hana ʻana o ka lāʻau lapaʻau e like me ka wā ma mua, e haʻi koke i kāu kauka.
Hiki i nā DMARD ke ʻano paʻakikī iki i ka wā mua. Nui nā ʻano lāʻau lapaʻau, a me nā inoa like ʻole. Akā, mai hopohopo. E kōkua kāu kauka iā ʻoe e koho i ka hui pū ʻana o nā lāʻau lapaʻau e kūpono loa i kou kūlana, hāʻawi i nā hopena maikaʻi loa, a me nā hopena ʻaoʻao liʻiliʻi loa. Mai kānalua e nīnau iā ia i nā nīnau āu e loaʻa ai.
Leka Lawe-Home
- He ʻano lāʻau lapaʻau kūikawā nā DMARD i hoʻohana ʻia e mālama i nā maʻi autoimmune. Hana lākou ma ka hōʻoluʻolu ʻana i kāu ʻōnaehana pale.
- ʻAʻole hana koke kēia mau lāʻau lapaʻau e like me nā lāʻau ʻeha. Hiki ke hala i nā pule a i ʻole nā mahina e ʻike ai i nā hopena. No laila e hoʻomanawanui a hoʻomau i ka hoʻohana ʻana iā lākou.
- Hiki i kekahi poʻe, ʻoiai ʻaʻole nā kānaka āpau, ke loaʻa i nā hopena ʻaoʻao. No laila, he mea nui e mālama mau i ka launa pū ʻana me kāu kauka.
- Mai hoʻololi koke i ka nui i kuhikuhi ʻia a i ʻole e hoʻōki koke i ka lawe ʻana i ka lāʻau me ka ʻole o ke aʻo ʻana a kāu kauka.
- Inā he mau nīnau kāu e pili ana i kāu lāʻau lapaʻau a maʻi paha, e nīnau i kāu kauka.
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