E kamaʻilio kākou e pili ana i ka Goodpasture Syndrome, ka mea e hōʻino ai i nā māmā a me nā puʻupaʻa i ka manawa like.

E noʻonoʻo i ka mea e hiki mai ana inā ʻo ko kākou pūʻali koa ponoʻī, ko kākou ʻōnaehana pale kino , ka mea i manaʻo ʻia e pale i ko kākou kino mai nā maʻi , e kuhihewa koke a hoʻomaka e hoʻouka i ko kākou mau kino maikaʻi? ʻO ia kekahi ʻano maʻi kakaikahi akā koʻikoʻi loa i kapa ʻia ʻo Goodpasture Syndrome. I loko o kēia maʻi, ʻo kā kākou ʻōnaehana pale kino e hōʻino nui i ʻelua o nā kino koʻikoʻi loa i loko o ko kākou kino, ʻo ia hoʻi nā māmā a me nā puʻupaʻa . He mea nui loa ia e makaʻala i kēia no ka mea hiki ke hoʻoweliweli i ke ola inā ʻaʻole ʻike ʻia a mālama koke ʻia.

He aha maoli ka Goodpasture Syndrome?

I ka ʻōlelo maʻalahi, he maʻi autoimmune ʻo Goodpasture Syndrome. ʻO ia hoʻi, hele hewa ka ʻōnaehana pale o ko mākou kino, ka ʻōnaehana pale, a hoʻouka i kā mākou mau hunaola a me nā ʻiʻo ponoʻī.

I loko o kēia maʻi, hana ka ʻōnaehana pale i nā antibodies e kūʻē i kahi protein kūikawā i kapa ʻia ʻo collagen , i loaʻa i loko o ko kākou mau māmā a me nā puʻupaʻa. E noʻonoʻo i kēia collagen e like me ke kāpili e hoʻopaʻa ana i nā ʻāpana o ko kākou kino. No laila, i ka wā e hoʻouka ai kēia mau antibodies i kēlā collagen, hoʻomaka ka hōʻino nui ʻia o nā māmā a me nā puʻupaʻa.

He aha ke kumu o kēia kūlana?

ʻAʻole maopopo loa i nā kauka ke kumu e hoʻouka hewa ai kā mākou ʻōnaehana pale i kona mau kino ponoʻī ma kēia ʻano. Eia nō naʻe, aia kekahi mau kumu i manaʻo ʻia he kuleana ko lākou.

• Ka mana hoʻoilina : ʻOiai ke holo nei kēia maʻi i kekahi mau ʻohana, ua manaʻoʻiʻo ʻia aia paha kahi predisposition genetic i ia mea.
• Nā kumu o ke kaiapuni: Ka ʻike ʻia ʻana i kekahi mau kemika , e like me nā mea hoʻoheheʻe hydrocarbon a me nā herbicides e like me ka paraquat.
• Lepo metala: Ka hoʻopilikia mau ʻia e ka lepo metala.
• Nā lāʻau lapaʻau: Ka hoʻohana ʻana i nā lāʻau lapaʻau e like me ka cocaine.
• Puhipaka: ʻO ka puhipaka kahi kumu nui o kēia.
• Nā maʻi viral: Hiki ke hana ʻia kēia ʻano ma hope o kekahi mau maʻi viral.

ʻIke pinepine ʻia kēia maʻi i nā kāne ʻōpio, ʻoi aku hoʻi ka poʻe ma waena o 20 a 30 mau makahiki a me ka poʻe ma luna o 60 mau makahiki.

He aha nā hōʻailona? Pehea ʻoe e ʻike ai i kēia?

Hōʻike nā pae mua o kēia maʻi i nā hōʻailona laulā a maopopo ʻole. No laila, i kekahi manawa ʻaʻole paha e like me he mea koʻikoʻi lā. Akā, e holomua koke ana kēia maʻi.

E nānā i ka papa ma lalo no ke ʻano o kēia mau hōʻailona.

ʻOiai hiki i kēia maʻi ke hoʻoulu i ke kahe koko e hoʻoweliweli i ke ola mai nā māmā, ʻo ka hōʻino ʻana o ka māmā i ka wā lōʻihi he mea liʻiliʻi wale nō. Eia nō naʻe, ʻo ka hopena koʻikoʻi loa o kēia maʻi, ʻo ia ka hāʻule ʻana o nā puʻupaʻa . Inā hana ʻia kēia, pono paha ʻoe i ka dialysis no ke ola holoʻokoʻa a i ʻole kahi hoʻoili puʻupaʻa.

Pehea e ʻike ai ke kauka i kēia maʻi?

Inā ʻike ʻoe i hoʻokahi a ʻoi aku paha o nā hōʻailona a mākou i kūkākūkā ai, mai hoʻokaʻulua . E ʻike koke i ke kauka. ʻOi loa aku inā ʻoe e ʻū ana i ke koko, pilikia ka hanu ʻana, a i ʻole ke kahe ʻana o ke koko i loko o kou mimi, he pilikia ia.

Hiki i ke kauka ke kauoha i kekahi mau hoʻokolohua e hōʻoia i ka hōʻailona:

• Urinalysis: Nānā kēia hoʻāʻo no nā pae kiʻekiʻe o ka protein a me nā hunaola koko ʻulaʻula i loko o ka mimi. Hiki i kēia ke kōkua i ka hoʻoholo ʻana inā ua hōʻino ʻia nā puʻupaʻa.
• Hoʻāʻo koko: Nānā ʻia kou koko no nā antibodies kikoʻī e hoʻouka ana i nā māmā a me nā puʻupaʻa.
• ʻO ke kiʻi X-ray o ka umauma: Hiki i kēia ke nānā i nā hōʻino i nā māmā, e like me nā kiko keʻokeʻo ʻē aʻe i hoʻokumu ʻia e ke kahe koko.
• Biopsy: I kekahi manawa lawe ʻia kahi ʻāpana liʻiliʻi o ka ʻiʻo mai kahi puʻupaʻa a i ʻole ka māmā a nānā ʻia ma lalo o kahi microscope. Hiki i kēia ke hōʻoia inā loaʻa nā antibodies Goodpasture Syndrome a me ka nui o ka pōʻino i loaʻa i nā puʻupaʻa.

He aha nā lāʻau lapaʻau no kēia?

Ke ʻike ʻia kēia maʻi, pono e hoʻomaka koke a ikaika ka lāʻau lapaʻau. ʻO nā pahuhopu nui o ka lāʻau lapaʻau:

• Ke kaua nei i nā antibodies ʻino.
• Ke kāohi nei i ka hōʻiliʻili ʻana o ka wai keu i loko o ke kino.
• Ke kāohi nei i ke koko kiʻekiʻe.
• Ke kāohi nei i ka hōʻino ʻana i nā māmā a me nā puʻupaʻa.

ʻO ka maʻamau, pili kēia i ka lāʻau lapaʻau:

1. Nā lāʻau pale ʻana i ka maʻi: Hāʻawi ʻia nā lāʻau e like me ka cyclophosphamide a me nā corticosteroids. Hana kēia mau lāʻau ma ka hōʻemi ʻana i ka hana o kā mākou ʻōnaehana pale a me ka hoʻōki ʻana i ka hana ʻana o nā antibodies ʻino. I kekahi manawa pono e hāʻawi ʻia nā dosis kiʻekiʻe o nā steroids ma ke ʻano intravenous e kāohi i ke kahe ʻana o ke koko i loko o nā māmā.

2. Plasmapheresis: He hana paʻakikī iki kēia. I ka ʻōlelo maʻalahi, pili ia i ka lawe ʻana i kahi liʻiliʻi o kou koko, e kau ana i loko o kahi mīkini kūikawā, a hoʻokaʻawale i ka ʻāpana wai, i kapa ʻia ʻo plasma, nona nā antibodies ʻino. A laila, ua hui pū ʻia nā ʻāpana maikaʻi i koe o ke koko (nā ʻulaʻula a me nā keʻokeʻo koko) me kahi pani plasma ʻē aʻe a hoʻihoʻi ʻia i kou kino. Hoʻopau kēia i nā antibodies weliweli mai ke koko. Pono paha e hana ʻia kēia lāʻau i kēlā me kēia lā no kekahi mau pule.

Hiki ke hala kēia lāʻau i 6 a 12 mau mahina. Hiki ke hala i kekahi mau pule a i ʻelua mau makahiki e hoʻōla piha ai. I loko o kēia manawa, pono paha kekahi mau maʻi i ka oxygen hou a i ʻole kahi ventilator. Pono paha nā hoʻoili koko.

ʻO Goodpasture Syndrome Sinhala, maʻi māmā, maʻi puʻupaʻa, ʻōnaehana pale, maʻi autoimmune sinhala, ʻū ʻana i ke koko, koko i loko o ka mimi