Ua ʻike anei ʻoe i nā leka ʻekolu LDH i ka nānā ʻana i kahi hōʻike koko? Ua kauoha paha kāu kauka i kēia hoʻāʻo. No nā poʻe he nui, he huaʻōlelo ʻē kēia, hiki ke huikau iki. No laila i kēia lā, e kamaʻilio kākou e pili ana i ke ʻano o ka hoʻāʻo LDH, no ke aha i hana ʻia ai, a me nā mea hiki iā ia ke ʻike, me ka maʻalahi loa, me he mea lā e haʻi aku ana mākou i kahi hoaaloha.
I ka ʻōlelo maʻalahi, he aha ka LDH?
E noʻonoʻo e pono ana kahi kaʻa a paikikala paha i ka ʻaila, diesel, a i ʻole
ka uila e holo ai. Pēlā ʻo LDH, a i ʻole Lactate Dehydrogenase, he protein kūikawā e kōkua ana i nā piliona o nā cell i loko o ko mākou kino e hana, ʻo ia hoʻi, e hana i ka ikehu. I ka lāʻau lapaʻau, kapa mākou i kēlā mau protein he enzymes. Aia kēia enzyme LDH i aneane i nā ʻiʻo āpau i loko o ko mākou kino. No ka laʻana, hiki ke ʻike ʻia kēia mau mea i loko o ka puʻuwai, ke akepaʻa, nā puʻupaʻa, nā ʻiʻo, ka lolo, nā cell koko ʻulaʻula, a me nā māmā. ʻO ka maʻamau, aia kēia mau mea i loko o nā cell. No laila, inā ua hōʻino ʻia kahi ʻiʻo a cell paha i loko o ke kino no kekahi kumu, e like me ke kahe ʻana o ke koko i ka wā e loaʻa ai kahi ʻeha, ʻo ka enzyme LDH i loko o kēlā mau cell i hōʻino ʻia e kahe i loko o ke koko.
Ana ka hoʻāʻo LDH i ka nui o ka LDH i hōʻiliʻili ʻia i loko o ke koko. ʻO ia hoʻi, ua like kēia me kahi hōʻailona e haʻi mai iā mākou inā he pōʻino i nā ʻiʻo ma kekahi wahi o ko mākou kino.
No ke aha e haʻi aku ai ke kauka iā ʻoe e hana i kahi hoʻokolohua LDH?
Aia kekahi mau kumu e noi ai ke kauka iā ʻoe e hana i kēia hoʻokolohua. Hiki iā ia ke hāʻawi iā ʻoe i kahi manaʻo ʻaʻole wale no hoʻokahi maʻi, akā, he nui nā mea.
- Inā ʻoe e kānalua nei he hōʻino ʻia nā ʻiʻo o ke kino, e hōʻoia.
- E nānā i nā kūlana olakino i loaʻa mua , e like me ka anemia , ka maʻi akepaʻa , ka maʻi puʻupaʻa , a i ʻole kahi maʻi.
- E hoʻomaopopo i ke koʻikoʻi o kekahi mau maʻi kanesa .
- E ʻike inā he kūpono nā lāʻau lapaʻau maʻi kanesa, e like me ka chemotherapy, a pehea lākou e pili ai i ke kino.
- Inā ua hōʻiliʻili ka wai ma nā ʻāpana like ʻole o ke kino (umauma, ʻōpū), e ʻike i ke kumu o ia mea.
ʻO ka mea nui, ʻo ka pae LDH kiʻekiʻe wale nō ke ʻano he *hiki* paha ke hōʻino ʻia nā ʻiʻo ma kekahi wahi o ke kino. No ka ʻike pono ʻana i kona wahi a me ke kumu, pono nā hoʻokolohua hou aʻe.
ʻO ka pilina ma waena o LDH a me ke olakino o ke akepaʻa
I ke kamaʻilio ʻana e pili ana i nā pae LDH, ʻaʻole hiki iā mākou ke pale aku i ke kamaʻilio ʻana e pili ana i ke akepaʻa. No ka mea, ʻo ke akepaʻa kekahi o nā ʻōkana nui loa o ko mākou kino. ʻO ia kekahi kahi e nui loa ai ka enzyme LDH. Ke hōʻino ʻia ke akepaʻa, make nā cell i loko. A laila hōʻiliʻili ka LDH i loko o kēlā mau cell i loko o ke koko. ʻO ia ke kumu e piʻi ai ka pae LDH i nā maʻi akepaʻa.
- Pae 1 - Hepatitis: ʻO kēia ka wā e pehu ai nā hunaola o ke akepaʻa. Hiki ke hana ʻia kēia e nā mea e like me nā maʻi viral a me ka inu nui ʻana i ka waiʻona . I kēia pae, piʻi ka pae LDH i ka wā e hōʻino ʻia ai nā hunaola o ke akepaʻa.
- Pae 2 - Fibrosis: Ke hoʻomau nei ka hōʻino ʻana o ke akepaʻa, hoʻomaka nā ʻōpala (scars) e hana ma ke akepaʻa. ʻO kēia ke kumu e lilo ai ke akepaʻa i mea ʻoʻoleʻa iki.
- Pae 3 - Cirrhosis: ʻO Cirrhosis ka wā e holomua ai kēia ʻeha i kahi e hiki ʻole ai i ke akepaʻa ke hana pono. I kēia pae, hiki ke hoʻokiʻekiʻe nui ʻia nā pae LDH.
- Kahua Hope Loa - Ka Holo ʻole ʻana o ke Ake : ʻO kēia ke kahua koʻikoʻi loa. ʻO nā hōʻailona e komo pū me ka melemele o nā maka ( jaundice ), ka pehu ʻana o ka ʻōpū, a me ka nausea .
No laila, he mea nui loa ia e nānā i ka pae LDH o kekahi mea e kānalua nei i ka maʻi akepaʻa.
Pehea e hana ʻia ai kēia hoʻāʻo LDH? He mea anei ia e makaʻu ai?
ʻAʻole loa. He mea maʻalahi loa ia. ʻO ka mea wale nō āu e hana ai, ʻo ia ke lawe i kahi koko liʻiliʻi mai kahi aʻa koko ma kou lima i loko o kahi syringe liʻiliʻi. Ua like ia me ka hāʻawi ʻana i ke koko. ʻAʻole i ʻoi aku ma mua o ʻelima mau minuke. Ma mua o kēia hoʻāʻo,
he mea nui e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau, nā huaora, a i ʻole nā mea hoʻohui āu e lawe nei. I kekahi mau hihia kūikawā, hiki ke ana ʻia nā pae LDH i loko o kahi wai kino ʻē aʻe ma mua o ke koko. No ka laʻana, hiki ke hana ʻia kahi puncture lumbar e nānā i ka LDH i loko o ka wai cerebrospinal e kōkua i ka ʻike ʻana i nā maʻi e like me ka meningitis.
Pehea e maopopo ai iaʻu nā waiwai i loko o ka hōʻike?
I ke kamaʻilio ʻana e pili ana i nā waiwai i loko o ka hōʻike LDH, ʻo ka mea nui e hoʻomanaʻo ai, hiki ke ʻokoʻa iki nā pae maʻamau mai ka lab a i ka lab. No laila
, ʻo ke kanaka maikaʻi loa e ʻike i ke ʻano pololei o kāu hōʻike ʻo kāu kauka. Nā pae LDH maʻamau
ʻO ka pae maʻamau no ka pae LDH o kahi pākeke ma waena o 140 a me 280 mau ʻāpana i ka lita (140-280 U/L). Hiki ke kiʻekiʻe iki aʻe kēia waiwai i nā keiki a me nā ʻōpio.
LDH Kiʻekiʻe (LDH Kiʻekiʻe)
ʻO ka pae LDH i ʻoi aku ma mua o ka maʻamau he hōʻailona ia aia kahi hōʻino ʻia o nā ʻiʻo ma kekahi wahi o ke kino. Hiki i kēia ke loaʻa i nā kumu he nui.
- Anemia
- Nā maʻi o ke akepaʻa (Hepatitis, Cirrhosis)
- Maʻi puʻupaʻa
- Nā maʻi māmā
- Maʻi hohola
- ʻEha ʻiʻo
- Haʻihaʻi iwi
- ʻO ka maʻi pancreatitis
- nā maʻi e like me ka meningitis a me ka mononucleosis
- ʻO kekahi mau ʻano maʻi kanesa (leukemia, lymphoma, melanoma)
Eia nō naʻe,
i kekahi manawa hiki ke hoʻokiʻekiʻe ʻia nā pae LDH me ka ʻole o kekahi maʻi kumu. Eia kekahi laʻana, ma hope o ka hoʻoikaika kino nui ʻana, a inā ʻaʻole i lawelawe pono ʻia ka hāpana koko i loko o ka lab.
Hiki iā ʻoe ke ʻike i kahi o ka pōʻino? - LDH isoenzymes
ʻO kekahi mea nui e pili ana i ka LDH, aia he 5 mau ʻano like ʻole o ia mea, me nā ʻano like ʻole. Kāhea mākou i kēia mau isoenzymes LDH. Loaʻa kēlā me kēia ʻano i loko o nā ʻiʻo kikoʻī o ke kino. No laila, ma ka nānā ʻana i ka mea o kēia mau ʻano i hoʻonui ʻia i loko o ke koko, hiki iā mākou ke loaʻa kahi manaʻo maʻamau o ka ʻōkana i hōʻino ʻia.
| ʻAno LDH (Isoenzyme) | Nā wahi nui |
|---|
| LDH-1 | Nā hunaola puʻuwai a me ke koko ʻulaʻula |
| LDH-2 | Nā hunaola koko keʻokeʻo (loaʻa pū kekahi i loko o ka puʻuwai a me nā hunaola koko ʻulaʻula) |
| LDH-3 | Nā māmā |
| LDH-4 | Nā puʻupaʻa a me ka pancreas |
| LDH-5 | ʻAke a me nā ʻiʻo |
LDH haʻahaʻa
He maʻi laha ʻole kēia. ʻAʻole ia i manaʻo ʻia he pilikia koʻikoʻi. Hiki ke hana ia i ka wā he nui loa ka wikamina C i loko o ke kino a i ʻole ma muli o nā maʻi hoʻoilina laha ʻole.
Leka Lawe-Home
- He enzyme ka LDH i hoʻokuʻu ʻia i loko o ke koko ke hōʻino ʻia nā hunaola o ko kākou kino. ʻO ke ana ʻana i kēia e hōʻike ana i ka hōʻino ʻia o nā ʻiʻo i loko o ke kino.
- Mai hopohopo i ka piʻi koke ʻana o nā pae LDH. Hōʻike wale ia i kahi kānalua o kahi maʻi. Pono nā hoʻokolohua hou aʻe e hōʻoia i ia mea.
- Kōkua kēia hoʻāʻo i ka nānā ʻana i nā kūlana like ʻole e like me nā maʻi ate, nā maʻi puʻuwai, ke kanesa, a me nā maʻi ʻē aʻe.
- Mai hoʻoholo i kāu iho ma muli o nā waiwai i loko o kāu hōʻike. E kamaʻilio mau me kāu kauka e pili ana i ia mea a e kiʻi i nā kikoʻī mai iā ia.
- Hiki i nā pae LDH ke piʻi no kekahi manawa ma muli o nā kumu maʻamau, e like me ka hoʻoikaika kino nui. No laila, ʻaʻole nā pae kiʻekiʻe a pau he hōʻailona o kahi maʻi koʻikoʻi.
Hoʻāʻo LDH, Lactate Dehydrogenase, hoʻāʻo LDH Sinhala, hoʻonui ʻia o ka LDH, nā maʻi akepaʻa, hōʻino ʻia nā ʻiʻo, nā hoʻāʻo koko, nā hoʻāʻo lapaʻau, nā isoenzymes LDH, nā hōʻailona
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