Ke hōʻino nei nā lāʻau lapaʻau āu e lawe nei i kou mau pepeiao? E kamaʻilio kākou e pili ana i ka ototoxicity!

Ua manaʻo paha ʻoe e hiki i kekahi mau lāʻau lapaʻau, ʻoiai nā mea i hoʻohana ʻia e mālama i nā maʻi koʻikoʻi, ke hōʻino i ko kākou mau pepeiao, ʻo ia hoʻi ko kākou lohe a me ke kaulike? He mea hiki maoli kēia. I ka lāʻau lapaʻau, kapa mākou i kēia ʻano he ototoxicity. Mai hopohopo, he mea nui e makaʻala i kēia. E kamaʻilio kākou e pili ana i nā kikoʻī.

He aha ka ototoxicity?

I ka ʻōlelo maʻalahi, ʻo ka ototoxicity ka hōʻino ʻana i ko kākou pepeiao o loko ma ke ʻano he hopena ʻaoʻao o kekahi mau lāʻau lapaʻau. Inā mākou e nānā i ke ʻano o ka huaʻōlelo "ototoxicity", ʻo "oto" ke ʻano o "pepeiao" a ʻo "toxicity" ke ʻano o "poisoning". ʻO ia hoʻi, he ʻano e like me ka lāʻau make o ka pepeiao. Loaʻa i ko kākou pepeiao o loko nā pūnaewele sensory palupalu loa. Kōkua kēia mau pūnaewele iā mākou e lohe a mālama i ke kaulike i loko o ke kino. ʻO kekahi mau lāʻau lapaʻau, no ka laʻana, nā lāʻau lapaʻau no nā maʻi koʻikoʻi a me nā lāʻau lapaʻau no nā maʻi e like me ke kanesa, hiki ke hōʻino i kēia mau pūnaewele sensory. ʻO ia ka manawa e hana ʻia ai kēia ʻano i kapa ʻia ʻo ototoxicity.

He aha nā hōʻailona o ka ototoxicity?

ʻAʻole like kēia mau hōʻailona no nā kānaka a pau. I kekahi manawa, hiki ke ʻike koke ʻia nā hōʻailona ma hope o ka hoʻomaka ʻana i ka lāʻau lapaʻau. No kekahi poʻe, hiki ke ulu mālie a mālie nā hōʻailona. ʻO ka mea kupanaha, hiki i kekahi mau lāʻau lapaʻau ke hoʻoulu i kēia mau hōʻailona a hiki i ʻelima mau makahiki ma hope o ka hoʻomaka ʻana i ka lāʻau lapaʻau. ʻO ka pinepine, ʻo ka hōʻailona mua ka lohe ʻana i kahi leo kani i loko o ka pepeiao. Hiki ke like me kekahi e kamaʻilio ana me kekahi, a i ʻole he leo "kani" a i ʻole he leo "whooshing". Kāhea nā kauka i kēia tinnitus . Hiki iā Tinnitus ke lilo i hōʻailona mua o ka nalowale o ka lohe. ʻO nā hōʻailona ʻē aʻe:

• Ka nalowale o ka lohe (ma kekahi a i ʻole nā ​​pepeiao ʻelua).
• Manaʻo e like me ʻoe e nalowale ana kou kaulike i ka wā e hele ana, ʻoiai i ka wā e piʻi ai i ke alapiʻi.
• Ka paʻakikī o ka hele wāwae ʻana i ka pō a i ʻole ma nā wahi pouli.
• Pono e hele me kou mau wāwae i ke kaʻawale e mālama i ke kaulike.
• ʻO Oscillopsia ka manaʻo e like me nā mea e neʻe ʻole ana me he mea lā e wili ana. Ua kapa ʻia kēia he oscillopsia .
• Ke manaʻo nei e puni ana ka poʻo, me he mea lā e wili ana kou poʻo, me he mea lā e wili ana kou mau lima, a i ʻole e luhi ana.

E noʻonoʻo i ke ʻano o ka ʻoluʻolu ʻole inā manaʻo koke ʻoe i ka poniuniu i ka wā e hana ana i kāu mau hana o kēlā me kēia lā, a inā hoʻomaka ʻoe e maule i ka wā e hele ana? Eia nā hōʻailona e pono ai mākou e makaʻala.

Pehea ka hopena o kēia i nā keiki ʻōpio?

Inā loaʻa kēia ʻano maʻi i nā keiki ʻōpio, ʻoiai ka poʻe i lawa ka makahiki e aʻo ai e kamaʻilio, hiki iā ia ke lilo i mea keakea nui i kā lākou aʻo ʻana a me ke kamaʻilio ʻana me nā poʻe ʻē aʻe. Ma ke ʻano he mau mākua, pono mākou e makaʻala loa i kēia mau hōʻailona:

• Ka paʻakikī e noho kālele ana, inā ma ke kula a i ʻole ke aʻo ʻana i kahi mea ʻē aʻe.
• Luhi koke ke hoʻolohe ʻoe no ka manawa lōʻihi.
• Paʻakikī ke hoʻomaopopo i ka mea a haʻi e ʻōlelo nei, kānalua e ʻōlelo, a ʻaʻole paha e ʻōlelo iki. I kekahi manawa hiki i kēia ke kumu e lohi ai ka ʻōlelo a ke keiki.

Inā makemake nui ke keiki e aʻo i kekahi mea, akā nalowale koke kona hoihoi i ia mea, a inā ʻōlelo mau lākou ua luhi lākou, pono ʻoe e noʻonoʻo i kēia ma mua o ka manaʻo wale ʻana he hana kolohe ia.

No ke aha e hana ai kēia ototoxicity?

Wahi a nā kauka, aia ma mua o 200 mau ʻano lāʻau lapaʻau e hiki ke hōʻino i ko kākou pepeiao o loko (nā lāʻau ototoxic). Pono kekahi o kēia mau lāʻau lapaʻau i ke kauoha mai ke kauka. Akā, hiki ke kūʻai ʻia kekahi, no ka laʻana, kekahi mau lāʻau ʻeha, ma kahi hale kūʻai lāʻau me ka ʻole o ke kauoha.

ʻO ka mea nui, ʻo ka nui o nā lāʻau lapaʻau i ʻōlelo ʻia he mea ʻino i ka pepeiao he mau lāʻau lapaʻau ola koʻikoʻi ia. Eia kekahi laʻana, nā lāʻau lapaʻau no ke kanesa, a i ʻole nā ​​lāʻau lapaʻau no nā maʻi bacteria koʻikoʻi. I ia mau hihia, ʻoi aku ka maikaʻi o ka lawe ʻana i ka lāʻau lapaʻau, ʻo ia hoʻi ka hoʻopakele ʻana i ke ola , ma mua o ka pōʻino liʻiliʻi e hiki ke hana ʻia i ka pepeiao.

Eia kekahi, ʻo kekahi mau lāʻau `(ototoxic)` e hōʻeha wale inā lawe ʻia i nā nui kiʻekiʻe loa. ʻAʻole mākou e lawe pinepine i kēlā mau nui kiʻekiʻe. Aia kekahi mau papa nui o nā lāʻau e hiki ke hōʻeha i ka pepeiao:

Nā lāʻau antibiotic aminoglycoside

He ʻano antibiotic kēia i hāʻawi ʻia e mālama i nā maʻi bacteria. Me nā lāʻau anticancer, ua manaʻo ʻia kēia papa o nā lāʻau (aminoglycosides) ʻo ia ke kumu nui o ka ototoxicity. Eia kekahi mau laʻana:

• ʻAmikacin
• ʻO Gentamicin
• `(Kanamycin)`
• ʻO Neomycin
• ʻO ka Netilmicin
• ʻO ka Streptomycin
• ʻO Tobramycin
• `(Vancomycin)` (Hoʻokomo pū ʻia kēia i loko o kēia māhele i kekahi manawa)

Nā lāʻau lapaʻau chemotherapy

Nā lāʻau lapaʻau i hoʻohana ʻia e mālama i nā ʻano maʻi kanesa like ʻole. Hiki i kekahi o kēia mau mea ke hōʻino i nā pepeiao:

• ʻO Carboplatin
• ʻO Cisplatin

Nā lāʻau diuretics loop - "nā pila wai"

He mau lāʻau lapaʻau kēia e kōkua ai i nā puʻupaʻa e hoʻokuʻu i ka paʻakai a me ka wai keu mai ke kino ma o ka mimi. Ua kapa pū kekahi poʻe iā lākou he "nā pila wai." ʻO kekahi o kēia mau mea:

• `(Bumetanide)`
• `(ʻAkika Ethacrynic)`
• `( Furosemide )` (He lāʻau lapaʻau kēia i ʻike ʻia e ka poʻe he nui)
• `(Torsemide)`

Nā lāʻau lapaʻau a me nā kemika ʻē aʻe

ʻOiai he mea kakaikahi, hiki ke hana ʻia ka ototoxicity e:

• Kuina:Nā lāʻau lapaʻau i hāʻawi ʻia e mālama i ka malaria.
• ʻO Salicylates : He mau lāʻau hōʻoluʻolu ʻeha kēia ma ke kūʻai ʻana ma luna o ke kauka. ʻO ka ʻAspirin, ka mea a mākou e ʻike nei, he ʻano salicylate. Eia nō naʻe, ke lawe ʻia i nā nui kiʻekiʻe a no ka manawa lōʻihi e hiki mai ai nā pilikia.
• Nā kemika i ke kaiapuni: I kekahi manawa hiki ke hana ʻia kēia kūlana e nā mea e like me ka mercury , tin, lead, a me ke carbon monoxide i ke kaiapuni.

He aha nā kumu pilikia?

ʻAʻole like ka pilikia o ka loaʻa ʻana o kēia ʻano ototoxicity no kēlā me kēia kanaka. Ma muli o ka lāʻau lapaʻau āu e lawe nei, e wehewehe kāu kauka i kēia mau mea pilikia iā ʻoe. ʻO kekahi mau mea maʻamau:

• ʻO ke ʻano o ka lāʻau lapaʻau āu e lawe nei: ʻOi aku ka nui o ka pilikia o kēia ma mua o nā mea ʻē aʻe.
• Ka nui o ka lāʻau lapaʻau: Pehea ka nui e lawe ai.
• Pehea ka lōʻihi e lawe ai i ka lāʻau lapaʻau.
• Inā paha e lawe pū i kekahi mau lāʻau lapaʻau e hiki ke hōʻino i nā pepeiao. Inā pēlā, e piʻi aʻe paha ka pilikia.

Eia kekahi, ua ʻike nā kānaka ʻepekema he hopena paha nā genes (DNA) o kekahi poʻe . Ma ke ʻano kūikawā, hiki i ke ʻano genetic (a i ʻole ke ʻano) o kekahi poʻe ke hoʻonui i ka pilikia o ka ototoxicity i ka wā e lawe ai i kekahi mau antibiotic aminoglycoside.

Nā pilikia ma muli o ka ototoxicity

ʻO ka hōʻino ʻana i ka pepeiao o loko i hana ʻia e kēia mau lāʻau "ototoxic" he "hiki ʻole ke hoʻihoʻi ʻia ". ʻO ia hoʻi, hiki ke loaʻa nā pilikia lōʻihi me ka lohe a me ke kaulike. ʻOi loa aku i nā keiki ʻōpio, hiki i kēia mau pilikia lohe ke keakea i ko lākou hiki ke ʻōlelo, aʻo i ka ʻōlelo, a hoʻomohala i nā mākau e pono ai lākou e kamaʻilio me nā poʻe ʻē aʻe. E noʻonoʻo, inā ʻaʻole hiki i kahi keiki ke lohe pono i nā huaʻōlelo, pehea lā lākou e aʻo ai e hoʻohana i kēlā mau huaʻōlelo e ʻōlelo ai? Eia nō naʻe, inā ʻaʻole hiki ke hoʻohuli ʻia ka hōʻino, hiki i nā kauka ke nānā i kou kūlana, mālama i nā hōʻailona inā kū mai, a hāʻawi i ke kākoʻo e pono ai.

Pehea e ʻike ai i kēia maʻi?

Inā loaʻa iā ʻoe kēia mau hōʻailona, ​​​​pono paha ʻoe e ʻike i kahi loea pepeiao, ihu, a me ka ʻāʻī (otolaryngologist a i ʻole ENT loea) a i ʻole he audiologist. E hana lākou i nā hoʻokolohua like ʻole e nānā i kou pepeiao o loko, ma muli o kāu mau hōʻailona. ʻO ka mea nui loa , hiki i kāu kauka ke hoʻāʻo i kou lohe a me ke kaulike ma mua o ka hāʻawi ʻana iā ʻoe i kahi lāʻau lapaʻau i manaʻo ʻia he ototoxic.Eia kekahi, hiki iā ʻoe ke hana i kēia mau hoʻokolohua i kēlā me kēia manawa ʻoiai ʻoe e lawe ana i ka lāʻau lapaʻau. Ma kēlā ala, inā he loli ma ke ʻano he hopena ʻaoʻao o ka lāʻau lapaʻau, hiki iā ʻoe ke ʻike koke iā ia.

He aha nā hoʻokolohua e hana ʻia?

No ka ʻike ʻana i ke ʻano o ka hana ʻana o kou pepeiao i loko, hiki i kāu kauka ke hana i nā hoʻokolohua e like me kēia:

• Audiogram: Hoʻāʻo kēia i kou lohe ʻana i nā leo like ʻole, e laʻa me nā leo palupalu, nā leo nui, nā leo kiʻekiʻe a me nā leo haʻahaʻa (pitch), a me kou hoʻomaopopo ʻana i nā huaʻōlelo.
• Hoʻāʻo Auditory Brainstem Response (ABR): Hoʻāʻo kēia i ke ʻano o ka pane ʻana o kou aʻalolo auditory i nā leo a pehea e hele ai kēlā pane i ka lolo.
• Hoʻāʻo ʻia nā Otoacoustic Emissions (OAEs): Hoʻopuka nā ʻano lauoho lahilahi loa i loko o ka pepeiao o loko (nā hunaola lauoho i loko o ka cochlea) i nā haʻalulu lohi loa (nā haʻalulu kani) i ka pane ʻana i ke kani. Ana kēia hoʻāʻo i kēia mau haʻalulu e ʻike i ke ʻano o ka hana ʻana o nā hunaola.
• Pākahi hoʻāʻo Vestibular: ʻAʻole kēia he hoʻāʻo hoʻokahi, akā he moʻo o nā hoʻāʻo e nānā i nā pilikia kaulike. No ka laʻana, hiki ke komo pū me kēia nā hoʻāʻo e like me `(Videonystagmography - VNG)` (ka nānā ʻana i nā neʻe ʻana o nā maka), `(Vestibular Evoked Myogenic Potentials - VEMPs)` (ka nānā ʻana i nā pane o nā aʻalolo e pili ana i ke kaulike), `(Rotary chair test)` (ka hoʻāʻo ʻana i ka wā e noho ana ma kahi noho wili), a me `(video Head Impulse Testing - vHIT)`.

Pehea e mālama ʻia ai ka ototoxicity?

ʻO ka mea pōʻino, ʻo ka hoʻōki ʻana i kahi lāʻau lapaʻau ototoxic ʻaʻole ia e hoʻohuli i ka pōʻino i hana mua ʻia. Eia nō naʻe, ʻo ka hoʻōki ʻana i ka lāʻau lapaʻau a i ʻole ka hōʻemi ʻana i ka nui (inā hiki) hiki ke kōkua i ka pale ʻana i ka pōʻino hou aʻe. Eia nō naʻe, e like me kā mākou i ʻōlelo ai, he mea ola pinepine kēia mau lāʻau lapaʻau ototoxic. No laila, ʻaʻole hiki ke hoʻōki iā lākou a i ʻole ka hana ʻana i nā hoʻololi nui i kāu hoʻolālā lapaʻau. I kēlā mau hihia, e nānā kāu kauka i kāu pane i ka lāʻau lapaʻau a kōkua iā ʻoe e hoʻokele i kāu mau hōʻailona.

Nā mea hana a me nā ʻano hana e kōkua ai i ka hoʻokele ʻana i nā hōʻailona

ʻOiai ʻaʻole hiki ke hoʻihoʻi ʻia ka pōʻino, aia nā ala e kōkua iā ʻoe e ola me nā hōʻailona:

• Nā mea kōkua hoʻolohe: Kōkua kēia mau mea i ka poʻe me ka nalowale o ka lohe, ʻoiai ka poʻe paʻakikī ke lohe, e lohe maikaʻi i nā mea a e maʻalahi ke kamaʻilio ʻana.
• Nā mea hoʻokomo cochlear: He mau mea uila kēia i hoʻokomo ʻia i loko o ka pepeiao ma ke ʻoki ʻana. Hoʻohana pinepine ʻia lākou no ka poʻe me ka pohō lohe nui ʻaʻole i pane maikaʻi i nā mea kōkua lohe maʻamau.
• Hoʻoponopono hou ʻana o ka Vestibular:He hoʻomaʻamaʻa kūikawā kēia. E hana pū ʻoe me kahi mea lapaʻau vestibular a i ʻole ka mea lapaʻau kino e aʻo i nā hoʻomaʻamaʻa a me nā ʻano hana e kōkua i kou kino e hoʻololi a hoʻoponopono i nā pilikia kaulike i hoʻokumu ʻia e nā pilikia pepeiao o loko. Hiki i kēia ke kōkua i ka hōʻemi ʻana i nā hōʻailona e like me ka poniuniu a me ka paʻakikī i ka hele wāwae.

Hiki ke pale ʻia ka ototoxicity?

ʻAʻole hiki ke pale ʻia kēia ʻano maʻi i nā manawa a pau. I kekahi manawa, pono e hāʻawi i kahi lāʻau ototoxic e hoʻopakele i kou ola. Eia nō naʻe, inā ʻike mua ʻoe i nā hōʻailona, ​​​​hiki i kāu kauka ke kōkua koke iā ʻoe a hana paha i nā hana e hōʻemi ai i ka pōʻino hou aʻe. Inā ʻoe e lawe ana i kahi lāʻau lapaʻau e hōʻino nui i kou mau pepeiao, e nānā mau kāu kauka iā ʻoe. E haʻi pū ʻo ia iā ʻoe i nā hōʻailona e makaʻala ai a me nā hōʻailona e ʻike ai i ke kauka inā ʻike ʻoe iā lākou.

Pehea ka lōʻihi o kēia kūlana?

ʻAʻole hiki ke hoʻihoʻi ʻia ka hōʻino ʻana i ka pepeiao o loko i hoʻokumu ʻia e ka ototoxicity. ʻO ia hoʻi, he mau loa ka hōʻino. Eia nō naʻe, ma muli o kou kūlana, hiki i kāu kauka ke hoʻololi i kāu hoʻolālā lapaʻau (inā hiki) e pale i ka hōʻino hou aʻe a me nā hōʻailona mai ka ʻino ʻana. Eia nō naʻe, no ka mea, ʻaʻole hiki ke hoʻōki i ka lawe ʻana i ka lāʻau lapaʻau, e hoʻomohala kāu kauka i kahi hoʻolālā lapaʻau lōʻihi e kōkua iā ʻoe e hoʻokele i kāu mau hōʻailona. Ma muli o kāu hōʻailona a me ka lāʻau lapaʻau i kuhikuhi ʻia iā ʻoe, e kamaʻilio kāu kauka me ʻoe e pili ana i nā pilikia o ka lawe ʻana i ka lāʻau lapaʻau ototoxic.

Pehea e hiki ai iaʻu ke mālama iaʻu iho a me kaʻu keiki?

• E kamaʻilio me kāu kauka e pili ana i nā pilikia a me nā hopena ʻaoʻao o kekahi lāʻau lapaʻau i hāʻawi ʻia iā ʻoe. Mai makaʻu e nīnau i nā nīnau.
• Inā ʻike ʻoe i kekahi mau loli hou i kou lohe, kaulike, a i ʻole kekahi mau hōʻailona ʻē aʻe ma hope o ka hoʻomaka ʻana i kahi lāʻau lapaʻau āu e manaʻo ai he ototoxic, ʻoiai inā he mea liʻiliʻi ia, e ʻike koke i kāu kauka.
• Inā he makua a mea mālama paha ʻoe e hāʻawi ana i kēia lāʻau lapaʻau i kahi keiki liʻiliʻi, e makaʻala pono i nā loli i kāu keiki. Hiki ke paʻakikī ke ʻike i nā hōʻailona i nā keiki liʻiliʻi. Ma waho aʻe o ka ʻimi ʻana i nā hōʻailona o nā pilikia lohe a i ʻole ke kaulike, e makaʻala i nā hōʻailona e pilikia ana kāu keiki i ka noʻonoʻo ʻana a luhi mau paha. Hiki paha i ka hoʻonāukiuki a kāu keiki e ʻike nei ma muli o ka pilikia lohe. Inā he mau hopohopo kāu, e ʻike i kāu kauka no ka ʻōlelo aʻo.

Pehea ka wikiwiki o ka hoʻomaka ʻana o ka ototoxicity?

He ʻokoʻa ia mai kēlā kanaka a kēia kanaka. Hiki i kekahi poʻe ke ʻike koke i nā hopena ʻaoʻao ke hoʻomaka lākou e lawe i ka lāʻau lapaʻau. No kekahi poʻe, ʻaʻole paha e ʻike ʻia kēia mau hōʻailona a hiki i ʻelima mau makahiki ma hope o ka hoʻomaka ʻana o ka lāʻau lapaʻau. Loaʻa i kekahi mau lāʻau lapaʻau a me nā lāʻau lapaʻau nā hopena lohi. ʻO ia ke kumu he mea nui ka loaʻa ʻana o nā hoʻokolohua lohe maʻamau a kāu kauka e ʻōlelo ai e nānā i kou lohe.

E hoʻomanaʻo, he nui nā lāʻau lapaʻau e pili ana i ka ototoxicity, e like me nā antibiotics a me nā lāʻau chemotherapy, he mea nui ia no ke ola. ʻOiai hiki iā lākou ke hōʻino i ka pepeiao o loko, ʻo nā pono o ka lawe ʻana iā lākou, inā paha he mālama ʻana i ka maʻi a i ʻole ke hoʻopakele ʻana i ke ola, ʻoi aku ka nui ma mua o nā pilikia.

Inā ʻoe e lawe ana i kahi lāʻau lapaʻau i ʻike ʻia he mea ʻino i kou mau pepeiao, e kamaʻilio me kāu kauka e pili ana i nā hōʻailona hōʻailona e ulu ana i loko o kou pepeiao o loko. ʻO ka wikiwiki o kou ʻike ʻana i nā loli, ʻo ka wikiwiki o kāu kauka e hiki ai ke kōkua iā ʻoe a hāʻawi iā ʻoe i kahi hoʻolālā mālama kūpono.

ʻO ka mea nui loa e pono ai kākou e hoʻomanaʻo! (Leka Lawe-Home)

ʻAe, e nānā kākou i kahi hōʻuluʻulu manaʻo o nā mea a mākou i kamaʻilio ai e kōkua iā ʻoe e hoʻomanaʻo i kekahi o nā mea nui loa:

• ʻO ka Ototoxicity ka hōʻino ʻana i ka pepeiao o loko i hana ʻia e kekahi mau lāʻau lapaʻau. Hiki i kēia ke hoʻopilikia i ka lohe a me ke kaulike.
• E makaʻala i nā hōʻailona e like me ke tinnitus (ke kani ʻana i nā pepeiao), ka nalowale o ka lohe, a me ka dizziness.
• ʻOiai aia nā pilikia i ka wā e lawe ai i nā lāʻau lapaʻau e hoʻōla ola ai, ʻoi aku ka nui o nā pono o ka lāʻau ma mua o nā pilikia. Eia nō naʻe, he mea nui e makaʻala i nā pilikia.
• Inā ua kuhikuhi ʻia ʻoe i kahi lāʻau ototoxic, e kamaʻilio me kāu kauka e pili ana i ia mea a hele i nā hoʻokolohua i hoʻonohonoho ʻia.
• Inā ʻike ʻoe i kekahi mau hōʻailona hou, ʻoiai inā he liʻiliʻi lākou, e haʻi koke i kāu kauka. Hiki i ka mālama koke ke kōkua i ka pale ʻana i ka maʻi mai ka ʻino ʻana.

Nau ke kuleana e mālama i kou olakino. Lana ko mākou manaʻo e kōkua kēia ʻike iā ʻoe e hana pēlā!