Ua ʻike anei ʻoe i nā maʻi Prion, nā mea e hōʻino malū ai i ka lolo?

E noʻonoʻo, hoʻomaka koke kekahi āu i ʻike ai e hoʻololi i ko lākou hoʻomanaʻo, ʻano, a me ka hele ʻana me ka wikiwiki loa. Ua lohe anei ʻoe i kahi maʻi i paʻakikī i nā kauka ke ʻike a holomua koke? I kēia lā e kamaʻilio mākou e pili ana i kekahi o kēlā mau maʻi ʻē a kakaʻikahi loa. Kāhea mākou i kēia mau maʻi prion.

I ka ʻōlelo maʻalahi, he aha kēia mau maʻi prion?

ʻO nā maʻi Prion kahi hui o nā maʻi e hoʻopilikia i kou lolo a me ka ʻōnaehana nerve. Hiki iā lākou ke hoʻoulu i ka dementia koʻikoʻi a i ʻole ka paʻakikī o ka kaohi ʻana i kou kino, a hiki iā lākou ke lilo i mea ʻino loa. He mea kākaʻikahi loa lākou, me kahi o 350 mau hihia i hōʻike ʻia i kēlā me kēia makahiki ma ʻAmelika Hui Pū ʻIa. E nānā kākou i ke kumu o lākou. He mau protein liʻiliʻi nā Prion i loaʻa i loko o ko kākou lolo. Akā no kekahi kumu i ʻike ʻole ʻia, pelu hewa kēia mau protein, huikau, a lilo i mea ʻino. ʻO ka mea weliweli loa, ʻo kēia protein prion i pelu hewa ʻia hiki ke hoʻoulu i nā protein olakino ʻē aʻe e pelu hewa. E like me ka hiki i kahi hoaaloha maikaʻi ʻole ke hoʻomaʻi i nā poʻe ʻē aʻe. Hōʻiliʻili kēia mau protein i pelu hewa ʻia i loko o ka lolo a hoʻomaka e luku i nā hunaola lolo (neurons). ʻO kēia ke kumu o nā hōʻailona.

He aha nā ʻano nui o nā maʻi prion?

Hiki i nā maʻi Prion ke hoʻopilikia i nā kānaka a me nā holoholona. Aia kekahi mau ʻano nui e hoʻopilikia i nā kānaka. E nānā kākou i ke ʻano o lākou.

He aha nā hōʻailona o ka maʻi prion?

Hiki ke ʻike koke ʻia nā hōʻailona o ka maʻi prion. ʻO kēia mau mea e komo pū me nā loli koke i kou ʻano, ka hoʻomanaʻo, a me nā neʻe ʻana.

Nā kumu a me nā kumu pilikia no ka hoʻomohala ʻana i kēia maʻi

ʻO ka hapa nui o ka manawa, hiki mai nā maʻi e like me CJD me ke kumu ʻole, akā ua ʻike ʻia kekahi mau mea pilikia.

• Moʻolelo ʻOhana : Ma kahi o 15% o ka poʻe e loaʻa ana i kēia mau maʻi ma muli o kahi kīnā genetic (kahi kīnā i loko o ka gene i kapa ʻia ʻo `PRNP`) i hoʻoili ʻia ma o nā hanauna.
• Nā maʻi : He mea kākaʻikahi loa kēia. I kekahi manawa, hiki ke laha kēia maʻi i ka wā e hoʻoili ai i nā ʻiʻo mai kahi mea me ka maʻi, a i ʻole inā ʻaʻole i hoʻomaʻemaʻe pono ʻia nā lako i hoʻohana ʻia i ka wā o ke ʻoki ʻana.
• ʻAi ʻana i ka ʻiʻo i loaʻa i ka maʻi: ʻO ka ʻai ʻana i ka pipi i loaʻa i ka " maʻi pipi pupule " (Bovine Spongiform Encephalopathy ) hiki ke hana i kahi ʻano maʻi i kapa ʻia ʻo vCJD. I ka wā i laha ai ke ʻano ma ʻEulopa i nā makahiki 1990, ua make kekahi poʻe liʻiliʻi i ka maʻi. I kēia manawa, ua hoʻokau ʻia nā lula paʻa e pili ana i ka hānai ʻana i nā pipi a me ka hāʻawi ʻana i ke koko, no laila ua hoʻemi nui ʻia kēia pilikia.

Pehea e ʻike ʻia ai ka maʻi prion?

Hiki ke paʻakikī ke ʻike i kēia maʻi no ka mea hiki ke like nā hōʻailona me nā maʻi ʻē aʻe. Inā loaʻa iā ʻoe nā hōʻailona e like me ka poina ʻana, e kāpae mua kāu kauka i nā kumu ʻē aʻe, e like me ka hahau ʻana a i ʻole ka puʻupuʻu lolo. Hiki ke hana ʻia nā hoʻokolohua aʻe:

• Spinal Tap / Lumbar Puncture: Pili kēia i ke kau ʻana i kahi nila lahilahi ma waena o ʻelua o kou mau vertebrae a lawe i kahi hāpana liʻiliʻi o ke wai e hoʻopuni ana i kou lolo a me ke kaula spinal (cerebrospinal fluid). Hiki ke hoʻāʻo ʻia nā pae o kekahi mau protein i loko e loaʻa ai kahi manaʻo o ka maʻi.
• ʻO ke kiʻi MRI (Magnetic Resonance Imaging): Hoʻohana kēia i nā magnet ikaika a me nā nalu lekiō e kiʻi i nā kiʻi kikoʻī o ka lolo. Hiki iā ia ke hōʻike i nā loli kikoʻī i ka lolo i ʻike ʻia i nā maʻi prion.
• CT scan (Computerized Tomography): Hoʻohui ʻia kekahi mau kukuna X e hana i kahi kiʻi maopopo o ka lolo.

Ka mālama ʻana a me ka pale ʻana i ka maʻi

I kēia manawa, ʻaʻohe lāʻau lapaʻau no nā maʻi prion. ʻO nā lāʻau lapaʻau o kēia manawa ke kāohi wale i nā hōʻailona a hāʻawi i kahi hōʻoluʻolu i ka mea maʻi. Hoʻokomo pū kēia me nā mea ʻeha, nā antidepressants, a me nā lāʻau anti-anxiety. I ka wā e ʻoi aku ka ʻino o ke kūlana o ke kanaka me ka maʻi prion i kēlā me kēia lā, pono lākou i ke kōkua me nā hana o kēlā me kēia lā. Pono paha lākou e hoʻokomo ʻia kahi catheter e hoʻokahe i ka mimi, ka saline e pale ai i ka dehydration, a me ka hānai ʻana i ka paipu inā ʻaʻole hiki iā lākou ke ʻai.

Hiki ke pale ʻia ka maʻi?

ʻAʻohe ala e pale aku ai i nā maʻi prion hoʻoilina, akā hiki i kēia mau ʻanuʻu ke kōkua i ka hōʻemi ʻana i ka pilikia o ka hoʻolaha ʻana i ka maʻi ma o ka maʻi a i ʻole ka meaʻai:

• Ka hoʻomaʻemaʻe pono ʻana a me ka disinfection i nā lako lapaʻau.
• Inā loaʻa iā ʻoe kahi maʻi prion a i ʻole he moʻolelo ʻohana kou no ia mea, e pale i ka hāʻawi ʻana i nā ʻiʻo a i ʻole nā ​​​​​​ʻōpū.
• ʻAi wale i ka ʻiʻo i hōʻoia ʻia he palekana.

Ua kāohi maikaʻi ʻia ka laha ʻana o ka "maʻi bipi pupule" ma muli o nā lula paʻa i kau ʻia e nā ʻāina he nui a puni ka honua e pili ana i ka meaʻai a me ka pipi i hāʻawi ʻia i nā bipi. Nā Maʻi Prion, ka maʻi Creutzfeldt-Jakob, CJD, maʻi lolo, ʻōnaehana nerve, nalowale hoʻomanaʻo, dementia, maʻi bipi pupule, maʻi bipi pupule