Aia kekahi mau loli i nā hormones o kou kino? E makaʻala kākou i ka Prolactinoma (Prolactinoma)

Ua lilo koke anei kou pōʻaiapuni menstrual i mea ʻē? A i ʻole he wai keʻokeʻo waiū mai kou mau umauma, ʻoiai inā ʻaʻole ʻoe e hāpai a hānai waiū paha? Inā he kāne ʻoe, ua ʻike anei ʻoe i ka emi ʻana o ka hoihoi i ka moekolohe a i ʻole nā ​​​​​​kūlana pilikia ʻē aʻe? ʻO ke kumu o kēia mau mea he mea paha āu i noʻonoʻo ʻole ai. I kēia lā ke kamaʻilio nei mākou e pili ana i ia ʻano, ʻo ia hoʻi, kahi maʻi i kapa ʻia ʻo Prolactinoma.

I ka ʻōlelo maʻalahi, he aha ka Prolactinoma?

ʻO ka Prolactinoma kahi puʻupuʻu e ulu ana i loko o kahi gland liʻiliʻi e kokoke loa ana i ko kākou lolo, ma ke kumu o ka lolo, i kapa ʻia ʻo ka pituitary gland. I kēia manawa, mai makaʻu i ka wā e ʻōlelo ai mākou "puʻupuʻu." He puʻupuʻu ʻaʻole kanesa (benign) kēia. ʻO ia hoʻi, ʻaʻole ia he puʻupuʻu e hoʻoweliweli i ke ola e pālahalaha ana ma ke kino e like me ke kanesa. ʻO kēia ke ʻano maʻamau o ka puʻupuʻu e ulu ana i loko o ka pituitary gland.

ʻO kēia puʻupuʻu ke kumu o ko mākou kino e hana i ka nui o ka hormone i kapa ʻia ʻo prolactin ma mua o ka mea e pono ai. ʻO ka maʻamau, he mea nui kēia hormone prolactin no ka ulu ʻana o ka umauma o nā wahine a me ka hana ʻana o ka waiū no ka hānai waiū (lactation). Akā i ka wā e piʻi ai kēia hormone, loaʻa kahi kūlana i kapa ʻia ʻo hyperprolactinemia, hiki iā ia ke hana i nā pilikia like ʻole no nā wahine a me nā kāne.

Aia kekahi mau ʻano o ka prolactinoma?

ʻAe, ua māhele ʻia kēia mau nati i ʻelua ʻano nui ma muli o ko lākou nui. No ka hoʻomaopopo ʻana i kēia, e nānā i ka papa ma lalo.

He aha nā hōʻailona o kēia?

Aia nā hōʻailona i ka nui o ka hormone prolactin i hana ʻia a me ka nui o ka puʻupuʻu. E nānā kākou i kēia mau hōʻailona.

ʻOi aku ka nui o ka manawa e ʻike ai nā wahine i ke kūlana ma mua o nā hōʻailona e like me nā loli i ko lākou pōʻaiapuni menstrual a i ʻole ka hoʻokuʻu ʻana o ka umauma. Eia nō naʻe, ʻaʻole paha e ʻike ka poʻe e lawe ana i nā pila hoʻomalu hānau a i ʻole nā ​​​​lāʻau lapaʻau hormone ʻē aʻe i kēia mau hōʻailona. Eia kekahi, hiki ke lohi nā hōʻailona i nā wahine a me nā kāne i hala i ka menopause, hiki ke hoʻopaneʻe i ka ʻike ʻana.

He aha ke kumu o kēia?

ʻO kaʻoiaʻiʻo, ʻaʻole i loaʻa i nā kānaka noiʻi kahi kumu kikoʻī no Prolactinoma. ʻO ka hapa nui o ka manawa, hiki pinepine ia, me ke kumu ʻole. Eia nō naʻe, hiki i kekahi mau kūlana genetic ke hoʻonui i ka pilikia.

• ʻO ka neoplasia endocrine lehulehu (MEN) ʻano 1
• ʻAno 4 o nā kāne
• ʻ`Adenomas pituitary isolated ʻohana (FIPA)''

Pehea ʻoe e ʻike ai i kēia, e Kauka?

E nānā pono kāu kauka i kāu mau hōʻailona a me ka mōʻaukala olakino. A laila, e hana lākou i kahi hoʻokolokolo kino. A laila e paipai paha lākou i kekahi mau hoʻokolohua e hōʻoia i ka hōʻailona.

• Hoʻāʻo koko Prolactin: ʻO kēia ka hoʻāʻo maʻalahi loa. Inā hōʻoia kēia hoʻāʻo ua ʻoi aku ke kiʻekiʻe o kāu mau pae prolactin ma mua o ka maʻamau, e kuhikuhi ʻia ʻoe no nā hoʻokolohua hou aʻe e nānā i kahi puʻupuʻu.
• MRI a i ʻole CT scan: Hiki i kēia mau scan ke hōʻike pololei inā loaʻa kahi puʻupuʻu pituitary a, inā pēlā, pehea kona nui. Paipai pinepine nā kauka i kahi scan MRI.
• Hoʻāʻo koko pae Testosterone: Inā he kāne ʻoe, hiki i kāu kauka ke ʻōlelo pū e hoʻāʻo i kāu mau pae hormone testosterone.

Inā ua hōʻoia ʻia ka maʻi, hiki ke ʻōlelo ʻia e nānā i nā pae o nā hormones ʻē aʻe i loko o ka pituitary gland a loaʻa i kahi hoʻokolokolo maka e kahi ophthalmologist e ʻike inā ua pilikia kou ʻike inā he puʻupuʻu nui kou (macroprolactinoma).

He aha nā lāʻau lapaʻau no kēia?

ʻO ka nūhou maikaʻi, aia nā lāʻau lapaʻau kūpono loa no kēia. I ka hapanui o nā hihia, hiki ke hoʻomalu ʻia ke kūlana me ka lāʻau lapaʻau.

Nā lāʻau lapaʻau (nā lāʻau lapaʻau)

Hoʻomaʻamaʻa pinepine nā kauka i nā lāʻau lapaʻau i kapa ʻia ʻo dopamine agonists. Hiki i kēia mau lāʻau lapaʻau ke hoʻemi i ka prolactinoma a hoʻihoʻi i nā pae prolactin i ka maʻamau.

• ʻO Cabergoline lāua ʻo Bromocriptine: ʻO kēia nā lāʻau lapaʻau nui ʻelua i hoʻohana ʻia. ʻO kēia mau mea, ʻo cabergoline ke koho mua a nā kauka no ka mea ʻoi aku ka maikaʻi a emi iho nā hopena ʻaoʻao.
• Nā hopena ʻaoʻao: Hiki i kēia mau lāʻau lapaʻau ke hana i nā hopena ʻaoʻao liʻiliʻi e like me ka nausea, ka luaʻi ʻana, a me ka dizziness.
• Ka lōʻihi o ka lāʻau lapaʻau: I mea e pale ai i ka hoʻi hou ʻana mai o ka puʻupuʻu, pono ʻoe e lawe mau i kēia lāʻau lapaʻau no ka liʻiliʻi o ʻelua mau makahiki . Ma hope o ʻelua mau makahiki, inā ua hoʻi kou pae prolactin i ka maʻamau a ʻaʻole ʻike hou ʻia ka puʻupuʻu ma nā scan, e hoʻemi mālie kāu kauka i ka nui o ka lāʻau lapaʻau a hoʻōki hope.

ʻoki kino

ʻAʻole pono pinepine ke ʻoki kino. ʻO kēia ma nā hihia e like me kēia:

• Inā he mau hopena ʻaoʻao koʻikoʻi ka lāʻau lapaʻau.
• Inā ʻaʻole e emi ka puʻupuʻu me ka lāʻau lapaʻau.
• Inā pili kēia lāʻau me nā lāʻau lapaʻau ʻē aʻe āu e lawe nei.
• Inā he puʻupuʻu nui kou a pono e wehe ʻia ma mua o ka hoʻāʻo ʻana e hāpai.

ʻElua ʻano hana ʻoki kino.

1. ʻO ke ʻoki ʻana o Transsphenoidal: ʻO kēia ke ʻoki maʻamau. Maanei, wehe ʻia ka puʻupuʻu ma o kahi ʻoki liʻiliʻi i loko o ka ihu a i ʻole ma lalo o ka lehelehe luna.

2. ʻO ke ʻoki kino transcranial: Inā nui loa ka puʻupuʻu, e wehe ʻia ka puʻupuʻu ma o kahi puka liʻiliʻi ma ka iwi poʻo.

Hoʻōla radiation

ʻO ka radiation therapy kahi koho ʻekolu ke pane ʻole ke kanesa i ka lāʻau lapaʻau a i ʻole ke ʻoki kino. He lāʻau lapaʻau kakaikahi loa kēia.

He aha ka nānā ʻana no kēia maʻi?

He maikaʻi loa ka nānā ʻana no ka prolactinoma. Me ka mālama lapaʻau, hiki i ka 4 o 5 mau kānaka me nā puʻupuʻu liʻiliʻi ke hoʻihoʻi i ko lākou pae prolactin i ke ʻano maʻamau a hiki ke emi ka puʻupuʻu.

Hoʻomaʻamaʻa pinepine ʻia ke ʻoki kino. Ke hana ʻia e ke kauka ʻoki kino akamai, hiki ke hoʻihoʻi ʻia nā pae prolactin i ka maʻamau ma kahi o 90% o ka poʻe me nā puʻupuʻu liʻiliʻi a me 50% o ka poʻe me nā puʻupuʻu nui.