He kanaka ʻoe i loaʻa pinepine i nā maʻi ʻaleka? Hoʻomaka ʻoe e ʻānai ma hope o ka hanu lepo, loaʻa iā ʻoe nā ʻōhū ma hope o ka ʻai ʻana i ka meaʻai, a i ʻole ke kahakaha wale nei ʻoe i kou kino i kekahi manawa? I kēia lā, ke kamaʻilio nei mākou e pili ana i kahi koa liʻiliʻi akā koʻikoʻi loa ma hope o kēia mau mea āpau. Ua ʻike paha ʻoe i ka huaʻōlelo 'Basophils' ma kekahi o kāu mau hōʻike koko, ʻo ia hoʻi, ma ka 'Full Blood Count'. No laila, he aha kēia mau basophils ? No ke aha e pono ai ko mākou kino iā lākou? E kamaʻilio kākou e pili ana i kēia ma ke ʻano maʻalahi a maʻalahi hoʻi e hoʻomaopopo.
He aha maoli ka basophil?
I ka ʻōlelo maʻalahi, ʻo nā basophils kahi ʻano o nā keʻena koko keʻokeʻo ('White Blood Cell' - WBC) i loko o ko kākou koko. E noʻonoʻo ua like ko kākou kino me kahi ʻāina. A laila ʻo nā keʻena koko keʻokeʻo ka ikaika pale o kēia ʻāina. Aia nā mana like ʻole i loko o kēia ikaika. No laila, aia ʻelima ʻano o nā keʻena koko keʻokeʻo. ʻO nā basophils ka mea liʻiliʻi loa o nā ʻano ʻelima, ʻo ia hoʻi he ikaika kakaikahi loa lākou.
Aia i loko o kēia mau pūnaewele basophil he mau granules liʻiliʻi. Ua piha kēia mau granules i kahi kemika koʻikoʻi i kapa ʻia ʻo histamine. ʻO kēia histamine ke kuleana no ka ʻūlū, nā maka ʻulaʻula, a me ka ihu wai āu e loaʻa ai ke loaʻa iā ʻoe kahi allergy. Kōkua pū nā basophils i ka pale ʻana i ko mākou kino mai nā parasites a ho'ōla i nā ʻeha .
ʻAno a me nā waiwai o nā basophils
He mea nui loa kēia mau ʻano o nā basophils no nā kauka e ʻike ai i kekahi mau maʻi. E nānā kākou i kekahi ʻike e pili ana i kēia koa liʻiliʻi.
| ʻAno | Wehewehena |
|---|---|
| Ka nui | He liʻiliʻi loa kēia, ma kahi o 5-10 micrometers (µm) ka nui. |
| ʻAno a me ke kala | Ke hoʻopili ʻia kahi waihoʻoluʻu kūikawā (Wright-Giemsa stain), ʻike ʻia nā granules i piha i ka histamine i loko o kēia mau cell i ka poni ʻeleʻele. Hiki ke ʻike maʻalahi ʻia kēia mau mea ma lalo o kahi microscope. |
| Kikowaena kelepona (Nucleus) | ʻO ke kikowaena o ke kelepona, ʻo ia ke ʻano o ka leka 'S'. |
| Ke ola a me ka hānau ʻana | Hoʻopuka ʻia nā basophils i loko o ka iwi iwi i loko o ko kākou mau iwi. Ke hoʻopuka ʻia lākou ma laila, ola wale lākou no kahi o 60 mau hola ma hope o ke komo ʻana i ke koko. |
| Nā Māka ʻIli | ʻO kekahi mau protein kūikawā ma ka ʻili o kēia mau cell (e like me `CD-123`, `CD-193`) e kōkua i nā kauka e ʻike i nā maʻi e like me kekahi mau maʻi ʻaʻai koko (`Leukemia`). |
He aha ka lawelawe a nā basophils e hāʻawi ai i ko mākou kino?
ʻO ka hana nui o nā basophils ka hoʻokuʻu ʻana i ka histamine a mākou i kamaʻilio ai ma mua. Akā eia kekahi, hana kēia mau hunaola liʻiliʻi i kahi lawelawe nui no ko mākou kino.
- Ka palekana mai nā Allergens : Ke komo nā mea e like me ka lepo a me ka pollen i ke kino, hakakā ia iā lākou.
- Ke kaua ʻana i nā parasites: Hoʻāla ʻia kēia mau mea i ka wā o nā maʻi parasitic e like me nā pinworms .
- Ho'ōla ʻeha : Kōkua ia i ke kaʻina hana ho'ōla o nā ʻeha.
- Ke kāohi nei i nā ʻōpū koko: Hoʻokuʻu pū kēia mau pūnaewele i kahi kemika i kapa ʻia ʻo heparin, kahi e kōkua ai i ka hoʻopau ʻana i nā ʻōpū koko i makemake ʻole ʻia.
ʻO ka pilina ma waena o nā allergies a me nā basophils
E noʻonoʻo i kahi makika e nahu ana i kou lima. Ma hope o kekahi manawa, lilo ka ʻāpana i ʻulaʻula, pehu, a ʻānai nui, ʻeā? ʻO ia ka hana a ka histamine, ka mea i hoʻokuʻu ʻia mai nā basophils.
ʻO ka hana a ka histamine, ʻo ia ka hoʻonui ʻana i ke kahe o ke koko i ka wahi. A laila lawe mai kēia i ke koko hou aku i ka wahi, "holoi" iā ia, e kōkua ana i ka hoʻopau ʻana i ka allergen. ʻO kēia pehu a me ka mumū he ʻāpana ia o ke kaʻina hana ho'ōla.
Ke komo kahi mea hoʻonāukiuki i ke kino o ke kanaka me ka maʻi allergies, hana ka ʻōnaehana pale i kahi ʻano antibody i kapa ʻia ʻo Immunoglobulin E (IgE). Hele kēia IgE a hoʻopili i ka mea hoʻonāukiuki. A laila hele mai nā basophils a hoʻouka i kēia hui IgE-allergen, e hoʻokuʻu ana i nā histamine āpau i loko. ʻO ia ka manawa e loaʻa ai nā hōʻailona o kahi maʻi allergies.
- Ihu wai, ʻūhū
- Nā maka ʻulaʻula, maneʻo
- ʻĀʻī ʻāʻī
- ʻŌhūhū ʻili, maneʻo
- Ka paʻakikī o ka hanu ʻana i nā poʻe maʻi hānō
Pehea e nānā ai i ka pae o ka basophil i loko o kou koko?
Inā kauoha kāu kauka iā ʻoe e hana i kahi hoʻāʻo `Complete Blood Count (CBC)`, a i ʻole e like me kā mākou e kapa nei, he `helu koko piha,` e helu ʻia hoʻi ka helu basophil ma kēlā hōʻike. Hiki ke hoʻokomo ʻia kēia i loko o ka hōʻike ma nā ʻano ʻelua.
1. Ma ke ʻano he pakeneka (%): He aha ka pakeneka o nā hunaola koko keʻokeʻo āpau he basophils? ʻO ka maʻamau he waiwai liʻiliʻi loa kēia, ma kahi o 0.5% - 1%.
2. Helu Kūpono: ʻO ka helu maoli o nā basophils no kēlā me kēia milliliter o ke koko.
ʻO ka mea nui loa, ʻo ia ke hoʻohālikelike i kāu mau waiwai me ke kolamu 'Normal Range' a i ʻole 'Reference Range' ma kāu hōʻike lab, no ka mea, e ʻokoʻa iki paha kēia mau waiwai maʻamau ma muli o ka mīkini i hoʻohana ʻia ma kēlā me kēia lab.
| Pae | Manaʻo |
|---|---|
| Helu Maʻamau | Ma waena o 0.5% - 2% o nā hunaola koko keʻokeʻo. Hiki i ka waiwai paʻa ke loaʻa maʻamau mai 0.01 x 10⁹/L a i 0.08 x 10⁹/L. |
| Piʻi ka pae (Basophilia) | ʻOi aku ke kiʻekiʻe o nā pae basophil ma mua o ka maʻamau. |
| Pae haʻahaʻa (Basopenia) | Ke hāʻule nei nā pae basophil ma lalo o ka maʻamau. |
He mea weliweli anei ka hoʻonui ʻia ʻana o nā basophils (basophilia)?
ʻO ka piʻi ʻana o nā pae basophil i ʻike ʻia ma ke ʻano lapaʻau ʻo "Basophilia." Nui nā kumu no kēia.
- Nā Allergies: Nā allergies i nā mea e like me ka meaʻai, nā lāʻau lapaʻau, ka lepo, a pēlā aku.
- Nā maʻi: ʻO kekahi mau maʻi e like me ka moa a me ka maʻi palū.
- Nā pilikia thyroid: Haʻahaʻa ka hormone thyroid ('Hypothyroidism').
- Nā maʻi ʻili: Nā ʻano ʻili e like me ka eczema e like me ka atopic dermatitis.
- Nā maʻi koko: Nā kūlana e like me ka polycythemia vera.
- ʻO kekahi mau maʻi kanesa: Nā maʻi kanesa koko e like me ka leukemia myeloid maʻi (CML).
Mai hopohopo i kēia papa inoa. ʻO ka hapa nui o ka manawa, ʻo ka helu basophil i piʻi iki aʻe paha ma muli o kahi mea maʻalahi e like me ka maʻi allergy maʻamau. Akā pono ʻoe e waiho i kāu kauka e ʻike i ke kumu pololei. E hana ʻo ia i nā hoʻokolohua hou aʻe inā pono e hōʻoia i ke kumu.
He aha ka basopenia?
ʻO ka emi ʻana o nā pae basophil ua kapa ʻia ʻo "Basopenia." He ʻoi aku ka kakaikahi o kēia ma mua o "Basophilia." Hiki ke hana ʻia kēia e kekahi mau kumu.
- Kekahi mau maʻi.
- Ka hana nui ʻana o ka hormone thyroid (hyperthyroidism).
- He hopena maʻi ʻaleka koʻikoʻi a koke ('Anaphylaxis').
- ʻO kekahi mau maʻi o ka ʻōnaehana pale, no ka laʻana ʻo `Systemic Lupus Erythematosus (SLE)`.
Hiki i ka emi ʻana o nā basophils ke hoʻopilikia i ke kaʻina hana ho'ōla o ko mākou kino.
I ka manawa e ʻimi koke ai i ke aʻo lapaʻau
ʻOiai ʻaʻole weliweli kahi maʻi allergy maʻamau, i kekahi manawa hiki i ka ʻōnaehana pale ke pane nui. Ua kapa ʻia kēia ʻo 'Anaphylaxis'.
He pilikia olakino hoʻoweliweli ola ka anaphylaxis. Inā ʻike ʻoe a i ʻole kekahi i kekahi o kēia mau hōʻailona, e hele koke i ka keʻena pilikia haukapila kokoke loa (ETU).
- Ka pehu ʻana o nā lehelehe, ke alelo, a i ʻole ka maka
- Paʻakikī ka hanu ʻana
- Paʻakikī ke ale ʻana
- ʻUlaʻula a ʻulaʻula paha o ka ʻili ma ke kino holoʻokoʻa
- ʻEha ka ʻōpū, ka luaʻi ʻana, a i ʻole ka maʻi pākī
- Paʻa ka umauma a i ʻole ke kani ʻūlū
- Manaʻo poniuniu a nāwaliwali paha
I nā manawa e like me kēia, he mea nui loa ia ʻaʻole e hopohopo a e ʻimi koke i ke kōkua lapaʻau.
Leka Lawe-Home
- He ʻano koʻikoʻi nā basophils o ke koko keʻokeʻo i loko o kā mākou ʻōnaehana pale e hakakā nei i nā maʻi allergies a me nā maʻi parasitic.
- ʻO ka Histamine, ka mea i hoʻokuʻu ʻia e lākou, ke kumu o nā hōʻailona he nui o nā maʻi allergies, e like me ka maneʻo a me ka pehu.
- Inā ʻaʻole maʻamau ka pae basophil i loko o kāu hōʻike koko, mai hopohopo a kamaʻilio me kāu kauka. ʻO ka pinepine, he mea maʻalahi paha ke kumu.
- Inā loaʻa iā ʻoe nā hōʻailona allergy koʻikoʻi e like me ka paʻakikī o ka hanu ʻana a me ka pehu ʻana o ka maka, he pilikia ia. E hele koke i ka Emergency Department (ETU) o ka haukapila.
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