He aha kēia mau maʻi Motor Neuron? E hoʻomaopopo maʻalahi kākou iā lākou.

Ua noʻonoʻo paha ʻoe i ka maʻalahi o ka hana ʻana i kēia mau mea ke hele mākou, ke kamaʻilio me kahi hoaaloha, a i ʻole ke nau ʻana i kā mākou meaʻai? Ma hope o kēlā me kēia neʻe ʻana, kēlā me kēia hana, aia kahi hui o nā ʻelele koʻikoʻi loa i loko o ko mākou kino. ʻO lākou ka mea a mākou e kapa nei he mau neuron motor. Ua like lākou me kahi hui o nā kauwā mai ko mākou lolo e haʻi ana i ko mākou mau ʻiʻo e "hana i kēia."

Akā, e like me nā ʻāpana ʻē aʻe o ko kākou kino, hiki ke hōʻino ʻia kēia mau ʻelele. ʻO ia ka manawa e loaʻa ai iā kākou nā kūlana i kapa ʻia ʻo 'nā maʻi neuron motor'. Ua lohe paha ʻoe iā ALS. ʻO ia kekahi o nā maʻi nui ma kēia māhele. Akā aia kekahi mau ʻano maʻi neuron motor ʻē aʻe a kākou i lohe ʻole ai. No laila i kēia lā, e kamaʻilio kākou e pili ana iā lākou ma ke ʻano maʻalahi.

ʻO wai kēia mau 'neuron motor'?

I ka ʻōlelo maʻalahi, he ʻano aʻalolo nā neuron motor. ʻO kā lākou hana nui ka lawe ʻana i nā leka e pono ai ko mākou kino e neʻe. ʻElua ʻano nui o kēia.

1. Nā neuron motor luna: Aia kēia mau mea i loko o kou lolo . Hoʻouna lākou i nā leka mai kou lolo a i kou kaula iwi kuamoʻo. E like me ke luna ma kahi keʻena nui.

2. Nā neuron motor haʻahaʻa: Aia kēia mau mea i loko o kou iwi kuamoʻo . Lawe lākou i nā leka mai ka lolo a haʻi i ko mākou mau ʻiʻo, "ʻAe, e hoʻomaka e hana i kēia manawa." Ua like ia me kahi luna ma kahi lālā.

I kēia manawa, e noʻonoʻo e pili ana i ka mea e hana ʻia ke loaʻa iā ʻoe ka maʻi neuron motor. Hoʻomaka mālie kēia mau hunaola aʻalolo e make. A laila, ʻaʻole hiki i nā leka uila mai ka lolo ke hiki pono i nā ʻiʻo. Hoʻōki ka hoʻouna ʻana o nā leka i ka hapalua. I ka hala ʻana o ka manawa, lilo nā ʻiʻo i nāwaliwali a hoʻomaka e emi no ka mea ʻaʻohe o lākou pono no lākou. Ua kapa nā kauka i kēia ʻo 'atrophy', a i ʻole ka hoʻopau ʻana o nā ʻiʻo.

Ke hana ʻia kēia, nalowale mākou i ke kaohi o kā mākou neʻe ʻana. E lilo ana i mea paʻakikī ke hele, kamaʻilio, ale, a ma hope e hanu.

He aha nā ʻano nui o nā maʻi neurone motor?

E nānā kākou i kekahi o nā maʻi i ʻike nui ʻia a me nā maʻi i ʻike ʻole ʻia ma kēia māhele.

ʻO ka Sclerosis Lateral Amyotrophic (ALS)

ʻO kēia ka maʻi neuron motor maʻamau i ʻike ʻia i waena o nā pākeke.Hoʻopilikia ka ALS i nā neuron motor o luna a me lalo. ʻO kēia ke kumu o ka nāwaliwali mālie a me ka mae ʻana o nā ʻiʻo e kaohi ana i ka hele wāwae, ke kamaʻilio ʻana, ka nau ʻana, ka moni ʻana, a me ka hanu ʻana. Hiki nō hoʻi ke ʻoʻoleʻa a me ka ʻūlū ʻana o nā ʻiʻo.

ʻO ka hapa nui o ka manawa, ʻaʻohe kumu kikoʻī e loaʻa ai no ka ALS. Ua kapa ʻia e nā kauka he 'sporadic'. ʻO ke ʻano kēia, hiki i kekahi ke loaʻa iā ia. Eia nō naʻe, ma waena o 5% a me 10% o nā hihia he hoʻoilina . ʻIke pinepine ʻia nā hōʻailona ma waena o nā makahiki 40 a me 60.

ʻO ka Sclerosis Lateral Mua (PLS)

Ua like ka PLS me ka ALS, akā hoʻopilikia wale ia i nā neurons motor o luna . ʻOi aku ka lohi o ka maʻi ma mua o ka ALS. ʻO nā hōʻailona e komo pū me ka nāwaliwali a me ka ʻoʻoleʻa i nā lima a me nā wāwae, ka hele wāwae lohi, a me ka nalowale o ke kaulike a me ka hoʻonohonoho ʻana. Hiki ke lohi a hūpō ka ʻōlelo. ʻAʻole ia he koʻikoʻi e like me ka ALS, a ʻaʻole ia e pepehi i nā kānaka.

ʻO ka maʻi Bulbar Progressive (PBP)

He ʻano ALS maoli kēia. Nui ka poʻe me PBP e loaʻa i ka ALS i ka hopena, kahi e hoʻopilikia ai i nā neurons motor i loko o ke kumu o ka lolo, aia ma ke kumu o ka lolo.

Kōkua kēia mau neurons i loko o ke kumu o ka lolo iā mākou e nau, ale, a ʻōlelo. No laila, i ka wā e ulu ai ka PBP, lilo nā huaʻōlelo i mea paʻakikī ke ale i ka meaʻai, a lilo ia i mea paʻakikī ke kāohi i nā manaʻo . Hiki iā ʻoe ke ʻakaʻaka koke a uē paha me ke kumu ʻole.

ʻO ka Atrophy Muscular Holomua

ʻAʻole maʻamau kēia ʻano e like me ALS a i ʻole PBP. Hoʻopilikia nui ia i nā neurons motor haʻahaʻa . Hoʻomaka ka nāwaliwali ma nā lima. A laila laha ia i nā ʻāpana ʻē aʻe o ke kino. Lilo nā ʻiʻo i nāwaliwali a hiki ke loaʻa nā ʻūmiʻi. Hiki i kēia maʻi ke ulu i ALS i kekahi manawa.

ʻO ka Atrophy Muscular Spinal (SMA)

He kūlana hoʻoilina kēia. Hoʻokumu ʻia ʻo SMA e kahi kīnā i loko o kahi gene i kapa ʻia ʻo `SMN1`. Hoʻopuka kēia gene i kahi protein e pale ana i nā neurons motor. Ke nalowale kēlā protein, make nā neurons motor. Hoʻopilikia kēia i nā neurons motor haʻahaʻa. Ua māhele ʻia ʻo SMA i kekahi mau ʻano ma muli o ka makahiki e ʻike ʻia ai nā hōʻailona .

Ka Maʻi o Kennedy

He maʻi hoʻoilina nō hoʻi kēia. Akā, ʻo ka mea kūikawā o kēia, ʻo ia ka hopena o kēia maʻi i nā kāne wale nō . ʻOiai inā loaʻa i nā wahine ka gene e kōkua ana i kēia maʻi (nā mea lawe), ʻaʻole lākou e loaʻa nā hōʻailona. Eia nō naʻe, aia he 50% ka manawa e hoʻoilina ai ke keiki kāne a kēlā makuahine i kēia maʻi.

Hiki i nā kāne me kēia maʻi ke ʻike i ka haʻalulu o nā lima, ka ʻūlū ʻana o nā ʻiʻo a me nā ʻūmiʻi, ka nāwaliwali ma ka maka, nā lima, a me nā wāwae. Hiki nō hoʻi iā lākou ke paʻakikī i ka moni ʻana a me ka ʻōlelo ʻana.

Pehea ʻoe e noho ai me kahi maʻi e like me kēia?

ʻO ka wā e hiki mai ana o kekahi e noho ana me ka maʻi neurone motor e pili ana i ke ʻano o ka maʻi. E like me kā mākou i ʻike ai, ʻoi aku ka lohi o ka ulu ʻana o kekahi mau ʻano a ʻoi aku ka liʻiliʻi o ka ʻino ma mua o nā mea ʻē aʻe.

Hiki i nā lāʻau lapaʻau o kēia manawa a me nā ʻano lapaʻau like ʻole (e laʻa me ka hoʻōla kino, ka hoʻōla ʻōlelo) ke kāohi i nā hōʻailona a hoʻomaikaʻi nui i ke ʻano o ke ola . No laila, inā ʻoe a i ʻole kekahi āu i ʻike ai e ʻike nei i kēia mau hōʻailona, ​​ʻo ka mea maikaʻi loa e hana ai, ʻo ia ke ʻike koke i kahi kauka kūpono e loaʻa ai kahi hōʻailona pololei a hoʻomohala i kahi hoʻolālā lapaʻau.