Koj puas muaj mob ntshav qab zib hom 2? Tej zaum koj tus kws kho mob yuav tau sau ib lub tshuaj rau koj hu ua Jardiance. Tej zaum koj yuav xav paub ntxiv txog cov tshuaj no. Nws yog hom tshuaj dab tsi, muaj dab tsi tshwm sim rau koj lub cev, thiab koj yuav tsum ceev faj li cas. Yog li hnub no, cia peb tham luv luv txog Jardiance, nws ua haujlwm li cas, nws cov txiaj ntsig, thiab koj yuav tsum paub txog dab tsi.
Jardiance yog dab tsi? Nws ua haujlwm li cas hauv lub cev?
Jardiance yog ib yam tshuaj siv los kho cov neeg laus thiab cov menyuam yaus uas muaj ntshav qab zib hom 2. Nws ua haujlwm los ntawm kev tswj cov ntshav qab zib. Nws kuj pab txo qhov kev pheej hmoo ntawm kev mob plawv thiab mob hlwb rau cov neeg laus uas muaj ntshav qab zib. Txawm li cas los xij, nws tsis tau pom zoo rau hom ntshav qab zib hom 1. Nws kuj tseem siv rau cov neeg uas tsis muaj ntshav qab zib tab sis muaj lub plawv tsis ua haujlwm lossis kab mob raum.
Zoo, tam sim no cia peb saib seb qhov no ua haujlwm li cas. Hais yooj yim xwb, yam uas peb lub raum feem ntau ua yog lim cov suab thaj (glucose) hauv cov ntshav thiab rov nqus nws rov qab rau hauv lub cev. Lawv tsis pub nws tawm hauv cov zis.
Muaj ib qho protein tshwj xeeb uas pab lub raum ua txoj haujlwm no, hu ua SGLT2 (Sodium-glucose cotransporter-2) .
Cov tshuaj Jardiance thaiv qhov ua haujlwm ntawm cov protein SGLT2 ib ntus. Qhov no tso cai rau cov suab thaj ntxiv uas lub cev tsis tuaj yeem nqus rov qab los ntawm cov zis. Qhov no txo cov suab thaj hauv cov ntshav. Cov txheej txheem no kuj tseem yuav pab koj poob qee qhov hnyav thiab tswj koj cov ntshav siab .
Cov txiaj ntsig ntawm cov tshuaj no tau ua pov thawj li cas lawm?
Muaj ntau txoj kev tshawb fawb loj hauv kev kho mob tau ua tiav los nrhiav seb Jardiance muaj kev nyab xeeb thiab zoo npaum li cas. Cov kev tshawb fawb no feem ntau saib seb cov tshuaj no muaj txiaj ntsig zoo li cas hauv kev txo HbA1c (kev kuaj uas qhia txog cov ntshav qab zib nruab nrab hauv 3 lub hlis dhau los).
Cov kev tshawb fawb no suav nrog cov neeg laus uas muaj ntshav qab zib hom 2, cov menyuam yaus hnub nyoog 10-17 xyoo, cov neeg uas muaj kab mob raum, thiab cov neeg uas muaj kab mob plawv. Cov teebmeem ntawm cov tshuaj kuj tau muab piv rau lwm cov tshuaj kho mob ntshav qab zib (piv txwv li, insulin, metformin, glimepiride).
Zoo, tam sim no cia peb saib seb cov txiaj ntsig ntawm cov kev tshawb fawb no pom dab tsi. Nco ntsoov, cov no yog cov txiaj ntsig nruab nrab. Koj cov txiaj ntsig yuav txawv nyob ntawm koj lub cev.
| Cov txiaj ntsig rau cov neeg laus (Cov neeg laus uas muaj mob ntshav qab zib hom 2) | ||
|---|---|---|
| Kev Siv Tshuaj | Txo cov ntshav qab zib thaum yoo mov (mg/dL) | Txo HbA1c |
| Jardiance 10 mg (tsis muaj lwm yam tshuaj) | Kwv yees li ntawm 19 mg / dL | Txog li 0.7% |
| Jardiance 25 mg (tsis muaj lwm yam tshuaj) | Kwv yees li 25 mg/dL | Txog li 0.8% |
| Jardiance (nrog rau lwm yam tshuaj) | Kwv yees li ntawm 10 - 22 mg / dL | Nruab nrab ntawm 0.2% - 2.1% |
| Cov Txiaj Ntsig rau Cov Neeg Laus uas Muaj Kab Mob Plawv | |
|---|---|
| Kev Kho Mob | Feem pua ntawm cov neeg tuag los ntawm kev mob plawv, mob hlwb, lossis kab mob plawv |
| Jardiance 10 mg los yog 25 mg | 10.5% |
| Tshuaj Placebo | 12.1% |
Cov txiaj ntsig rau cov menyuam yaus thiab cov neeg mob raum
Jardiance tau pom tias txo tau cov HbA1c thiab cov ntshav qab zib thaum noj mov tsis tu ncua rau cov menyuam yaus hnub nyoog 10-17 xyoo. Nws kuj tau pab txo cov HbA1c rau cov neeg laus uas muaj ntshav qab zib thiab mob raum.
Puas muaj lwm cov tshuaj uas cuam tshuam nrog Jardiance?
Yog, nws yog ib qho tseem ceeb heev uas yuav tsum tau saib xyuas qhov no.
- Cov ntshav qab zib qis: Yog tias koj noj lwm yam tshuaj kho mob ntshav qab zib, tshwj xeeb yog insulin lossis sulfonylureas (xws li glimepiride), koj yuav muaj cov ntshav qab zib qis (hypoglycemia) thaum koj pib siv Jardiance. Yog li ntawd, koj tus kws kho mob yuav txo qhov koob tshuaj ntawm koj lwm yam tshuaj.
- Kev Qhuav Dej: Yog tias koj noj cov tshuaj diuretics, kev noj nrog Jardiance yuav ua rau qhuav dej. Yog li ntawd, nws yog ib qho tseem ceeb uas yuav tsum haus dej ntau.
- Lithium: Yog tias koj noj lithium rau kev mob hlwb, nws cov teebmeem yuav hloov pauv thaum koj pib Jardiance. Tham nrog koj tus kws kho mob txog qhov no thiab mus kuaj ntshav yog tias tsim nyog.
Yuav ua li cas kom tsis txhob muaj cov kev mob tshwm sim txaus ntshai?
Qhov no tseem ceeb heev. Txawm hais tias Jardiance yog ib yam tshuaj uas muaj txiaj ntsig zoo heev los xij, muaj qee qhov kev phiv loj heev uas peb yuav tsum paub txog.
1. Kab mob ntshav qab zib ketoacidosis (DKA):
- Qhov no yog qhov xwm txheej txaus ntshai me ntsis. Thaum lub cev siv tsis tau qab zib, nws siv lwm txoj hauv kev kom tau lub zog. Qhov no tsim cov tshuaj hu ua ketones . Thaum cov no sib sau ua ke hauv cov ntshav, lawv tuaj yeem ua rau muaj kev phom sij heev.
- Cov tsos mob: xeev siab, ntuav, mob plab, qaug zog heev, ua pa nyuaj.
- > Yog tias koj muaj cov tsos mob no, tsum tsis txhob noj Jardiance tam sim ntawd thiab mus ntsib kws kho mob lossis mus rau chav kho mob ceev hauv tsev kho mob (ETU). Qhov no yog xwm txheej ceev.
2. Kev kis kab mob:
- Cov tshuaj no ua rau cov suab thaj ntau ntxiv hauv cov zis, uas ua rau muaj kev pheej hmoo ntawm cov kab mob bacterial thiab cov poov xab. Cov kab mob tuaj yeem tshwm sim hauv txoj hlab zis, lub zais zis, thiab thaj chaw ntawm qhov chaw mos.
- Kab mob Fournier's Gangrene: Ib qho kab mob uas tsis tshua muaj, tab sis txaus ntshai heev uas tuaj yeem tshwm sim nyob ib puag ncig thaj chaw mos. Nrhiav kev kho mob tam sim ntawd yog tias koj mob, liab, lossis o ntawm thaj chaw ntawd nrog rau kub taub hau thiab qaug zog.
3. Teeb meem ceg thiab ko taw:
- Qee qhov kev tshawb fawb tau qhia txog kev nce me ntsis ntawm kev txiav ceg, tshwj xeeb tshaj yog rau cov neeg uas muaj kab mob peripheral artery.
- Yog li ntawd, xyuas koj txhais taw kom zoo txhua hnub.Yog koj muaj tej qhov txhab, mob qog, tawg, lossis tej cim qhia tias muaj kab mob, qhia rau koj tus kws kho mob tam sim ntawd.
4. Cov teebmeem rau lub raum:
- Kev qhuav dej tuaj yeem cuam tshuam rau kev ua haujlwm ntawm lub raum. Yog li ntawd, nws yog ib qho tseem ceeb uas yuav tsum haus dej ntau. Koj tus kws kho mob yuav hais kom kuaj ntshav los xyuas koj lub raum ua haujlwm.
5. Kev Ua Xua:
- Yog tias koj muaj kev tsis haum tshuaj hnyav xws li o ntawm daim di ncauj, lub ntsej muag, lossis tus nplaig, ua pa nyuaj, lossis ua pob khaus ntawm daim tawv nqaij, tsum tsis txhob noj tshuaj tam sim ntawd thiab nrhiav kev pab kho mob.
Yuav siv cov tshuaj li cas kom raug?
Jardiance yog ib lub tshuaj uas koj noj ib zaug ib hnub. Noj cov tshuaj (10mg lossis 25mg) uas koj tus kws kho mob sau ntawv.
- Zoo tshaj plaws noj thaum sawv ntxov: Feem ntau cov kws kho mob pom zoo kom noj thaum sawv ntxov. Qhov laj thawj yog vim nws ua rau muaj kev tso zis ntau zaus, yog li nws tuaj yeem tshwm sim thaum nruab hnub yam tsis cuam tshuam kev pw tsaug zog thaum hmo ntuj.
- Koj paub li cas tias cov tshuaj ua haujlwm?: Koj tuaj yeem qhia tau los ntawm qhov txo qis ntawm koj cov ntshav qab zib thiab HbA1c. Tab sis nws yuav siv sijhawm li 3 lub hlis rau koj HbA1c hloov pauv. Yog tias koj kuaj zis thaum koj noj Jardiance, nws yuav qhia tias muaj qab zib hauv koj cov zis. Qhov no yog qhov ib txwm muaj, tsis txhob txhawj txog nws. Nws txhais tau tias cov tshuaj ua haujlwm.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Jardiance yog tshuaj rau mob ntshav qab zib hom 2 uas txo cov piam thaj hauv cov ntshav los ntawm kev tso cov piam thaj hauv cov zis.
- Tsuas yog noj cov tshuaj uas koj tus kws kho mob tau sau tseg xwb, raws lub sijhawm uas tau teem tseg (qhov zoo tshaj yog thaum sawv ntxov).
- Haus dej ntau ntau thoob plaws hnub kom tiv thaiv kev qhuav dej.
- Nco ntsoov txog cov tsos mob ntawm cov ntshav qab zib qis (hypoglycemia) thiab cov tsos mob txaus ntshai ntawm diabetic ketoacidosis (DKA) (ntuav, mob plab, ua pa nyuaj). Nrhiav kev kho mob tam sim ntawd yog tias koj muaj cov tsos mob ntawm DKA.
- Xyuas koj txhais taw txhua hnub seb puas muaj qhov txhab, qhov mob, lossis cov cim qhia tias muaj kab mob.
- Tham nrog koj tus kws kho mob txog tej yam kev mob tshwm sim lossis teeb meem uas koj ntsib. Tsis txhob tsum noj koj cov tshuaj lossis hloov qhov ntau npaum li cas yam tsis tau kev qhia los ntawm kws kho mob.
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