Ib qho teeb meem kev noj qab haus huv uas peb feem coob muaj yog ntshav siab , lossis " ntshav siab " raws li peb txhua tus paub. Qee zaum, qhov no tuaj yeem tswj tau los ntawm kev noj cov tshuaj uas tus kws kho mob tau sau tseg. Tab sis rau qee tus neeg, txawm tias tom qab siv tsis yog ib, tsis yog ob, tab sis peb lossis plaub hom tshuaj, qhov ntshav siab no tsis tuaj yeem tswj tau thiab lawv nyob hauv qab kev nyuaj siab heev. Yog li ntawd, yog tias koj kuj muaj ntshav siab uas nyuaj rau tswj, qhov ua rau yuav yog ib qho mob hu ua Hyperaldosteronism , uas peb tsis tau hnov ntau txog. Cia peb tham txog qhov no yooj yim hnub no.
Zoo, yog li Hyperaldosteronism yog dab tsi?
Hauv lwm lo lus, Hyperaldosteronism yog qhov kev tsim cov tshuaj hormones hu ua aldosterone ntau dhau los ntawm cov qog adrenal hauv peb lub cev.
Xav txog nws, cov qog adrenal yog ob lub qog me me uas zaum zoo li lub hau saum peb lub raum . Cov tshuaj hormones aldosterone tsim los ntawm cov qog no yog qhov tseem ceeb heev. Nws pab tswj cov kua dej, sodium ( ntsev ) thiab potassium kom raug hauv peb lub cev. Ntawd yog, cov tshuaj hormones no pab lub cev khaws cov sodium thiab dej uas nws xav tau thiab tso cov potassium ntau dhau hauv cov zis .
Yog li, yog tias muaj qee qhov laj thawj uas cov tshuaj aldosterone no raug tso tawm ntau dhau, peb hu nws tias Hyperaldosteronism. Qhov tshwm sim tom qab ntawd yog tias lub cev khaws cov sodium thiab dej ntau dhau, thiab cov potassium poob qis heev. Qhov tshwm sim tseem ceeb ntawm qhov no yog ntshav siab, uas nyuaj heev rau tswj .
Vim li cas qhov xwm txheej no thiaj tshwm sim?
Hyperaldosteronism muaj ob hom loj nyob ntawm seb ua rau muaj li cas.
1. Mob Aldosteronism Thawj Zaug
Qhov teeb meem yog nyob ntawm lub qog adrenal nws tus kheej. Uas yog, lub qog adrenal nws tus kheej tsim cov tshuaj aldosterone ntau dhau yam tsis muaj kev tswj hwm. Muaj ntau yam ua rau qhov no.
| Vim li cas | Kev piav qhia |
|---|---|
| Adenoma | Qhov no yog qhov ua rau feem ntau tshwm sim. Ib qho qog nqaij hlav uas tsis yog mob qog noj ntshav uas tshwm sim hauv ib qho ntawm cov qog adrenal. Tus mob no kuj hu ua Conn's syndrome. |
| Kev loj hlob ntawm cov qog adrenal ob sab | Kev loj hlob ntawm ob qho tib si adrenal qog lossis kev loj hlob ntau dhau ntawm lawv cov hlwb. |
| Cov qog nqaij hlav | Tsis tshua muaj, qhov mob no kuj tuaj yeem tshwm sim los ntawm qog nqaij hlav hauv lub qog adrenal. |
| Cov ua rau muaj los ntawm noob caj noob ces | Nws kuj tseem tuaj yeem tshwm sim los ntawm ib qho mob caj ces hu ua familial hyperaldosteronism. |
2. Kab mob siab ntau dhau (Secondary Hyperaldosteronism)
Qhov no tsis muaj teeb meem dab tsi nrog lub qog adrenal. Txawm li cas los xij, vim muaj lwm yam mob hauv lub cev, lub qog adrenal raug txhawb nqa thiab tsim ntau aldosterone. Qhov no tshwm sim los ntawm kev ua kom lub renin-angiotensin-aldosterone system hauv peb lub cev ua haujlwm.
| Tej yam mob uas yuav tshwm sim |
|---|
| Kab mob raum (cov hlab ntsha uas muab ntshav mus rau lub raum nqaim) |
| Lub plawv tsis ua haujlwm |
| Kab mob siab ntev |
| Cev xeeb tub |
| Ib qho qog uas tsim cov renin |
Cov tsos mob ntawm qhov no yog dab tsi?
Nco ntsoov, cov tsos mob tseem ceeb thiab feem ntau ntawm tus kab mob no yog ntshav siab , uas nyuaj heev rau tswj nrog ob peb yam tshuaj.
Ntxiv rau cov tsos mob ntawm ntshav siab, cov tsos mob ntawm cov potassium qis hauv lub cev kuj tuaj yeem pom. Qee zaum qhov mob no tuaj yeem muaj yam tsis muaj tsos mob.
| Pawg tsos mob | Cov yam ntxwv pom tseeb |
|---|---|
| Vim yog ntshav siab | Mob taub hau, kiv taub hau, pom kev tsis meej, kab mob plawv. |
| Vim yog cov potassium qis (Hypokalemia) | Cov mob xws li loog ntawm ob txhais ceg, cov leeg tsis muaj zog, mob plab, thiab tuag tes tuag taw ib ntus. |
| Vim yog qhov tsis sib npaug ntawm cov kua dej thiab ntsev | Yuav tsum tau tso zis ntau zaus, sawv ntxov mus tso zis thaum hmo ntuj, nqhis dej heev, qaug zog heev. |
Kuv yuav ua li cas thiaj paub tias qhov no muaj?
Yog tias koj muaj ntshav siab uas nyuaj rau tswj, koj tus kws kho mob yuav xav tias muaj tus mob no thiab yuav kuaj ntau zaus.
- Kev Kuaj Ntshav: Koj cov ntshav cov potassium, aldosterone, thiab renin raug kuaj xyuas. Hauv thawj hyperaldosteronism, potassium qis thiab aldosterone siab. Hauv theem ob hyperaldosteronism, cov renin kuj siab.
- Kev kuaj zis: Cov zis uas tau sau los ntawm 24 teev yuav raug kuaj seb puas muaj potassium.
- Kev kuaj tshuaj ntsev: Muab cov tshuaj sodium rau 3 hnub lossis muab tshuaj ntsev rau hauv cov leeg ntshav rau 4 teev, thiab tom qab ntawd kuaj xyuas cov qib aldosterone hauv cov ntshav lossis zis.
- Kev kuaj duab: Ib qho kev kuaj xws li CT scan tuaj yeem siv los kuaj xyuas seb puas muaj qog lossis loj hlob ntawm cov qog adrenal.
- Kev kuaj cov hlab ntsha adrenal:Qhov kev kuaj no yog ua yog tias cov kev luam theej tsis muaj txiaj ntsig. Qhov no suav nrog kev coj cov ntshav los ntawm cov leeg ntawm ob lub qog adrenal los txiav txim siab seb qhov teeb meem puas yog nyob rau hauv ib lub qog lossis ob qho tib si. Qhov no feem ntau ua ua ntej phais.
- Kev kuaj noob caj noob ces: Yog tias ib tug neeg hnub nyoog qis dua 20 xyoo muaj tus mob no lossis yog tias ib tug neeg hauv tsev neeg tau muaj tus mob no, lawv yuav raug xa mus kuaj noob caj noob ces.
Yuav kho li cas?
Cov kev kho mob nyob ntawm seb qhov ua rau thiab hom mob no yog dab tsi.
- Kev Phais Mob: Yog tias qhov teeb meem yog qog ntawm ib lub qog adrenal, koj tus kws kho mob feem ntau yuav pom zoo kom phais laparoscopic kom tshem tawm cov qog. Qhov no suav nrog ob peb qhov me me, uas tuaj yeem pab koj rov zoo sai dua thiab txo koj qhov kev nyob hauv tsev kho mob.
- Tshuaj: Yog tias muaj teeb meem nrog ob lub qog adrenal (bilateral hyperplasia), phais tsis yog ib qho kev xaiv. Hloov chaw, cov tshuaj uas thaiv kev ua haujlwm ntawm cov tshuaj hormones aldosterone (piv txwv li, spironolactone, eplerenone) raug muab. Txawm hais tias cov no tsis kho tus kab mob, lawv tuaj yeem tswj nws cov teebmeem.
- Lwm yam kev kho mob: Hauv hyperaldosteronism theem ob, qhov mob hauv qab (piv txwv li, kab mob plawv, renal artery stenosis) raug kho.
- Kev hloov pauv hauv lub neej: Txawm hais tias kev kho mob li cas los xij, nws yog ib qho tseem ceeb uas yuav tsum hloov pauv qee yam hauv lub neej kom tswj tau ntshav siab.
- Tsis txhob haus dej cawv
- Tso kev haus luam yeeb
- Kev tawm dag zog tsis tu ncua
- Tswj qhov hnyav ntawm lub cev
- Txo cov ntsev (sodium) noj hauv kev noj haus
Yog tias tsis kho, muaj tej yam txaus ntshai dab tsi?
Yog tias hyperaldosteronism tsis raug kho kom zoo, cov ntshav siab ntev thiab cov potassium qis tuaj yeem ua rau muaj teeb meem loj.
- Ntshav siab tuaj yeem ua rau: mob plawv nres, mob hlwb, mob plawv tsis ua haujlwm, mob raum, thiab txawm tias tuag ua ntej lub sijhawm.
- Cov potassium qis tuaj yeem ua rau muaj cov mob xws li: cov leeg tsis muaj zog, tuag tes tuag taw, cem quav, teeb meem nrog kev ua haujlwm ntawm insulin, thiab ntshav qab zib.
Yog li ntawd, yog tias koj muaj cov tsos mob xws li ntshav siab uas nyuaj rau tswj, nqhis dej ntau dhau, tso zis ntau zaus, lossis cov leeg tsis muaj zog, nco ntsoov mus ntsib koj tus kws kho mob thiab tham txog nws. Tsis txhob ntshai, qhov no yog ib qho mob uas tuaj yeem kuaj mob thiab kho tau.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Hyperaldosteronism yog thaum koj cov qog adrenal tsim cov tshuaj hormone aldosterone ntau dhau.
- Cov tsos mob tseem ceeb ntawm qhov no yog ntshav siab uas nyuaj rau tswj txawm tias siv ntau yam tshuaj los xij.
- Tsis tas li ntawd xwb, tej zaum yuav muaj cov tsos mob xws li cov potassium qis hauv lub cev, cov leeg tsis muaj zog, thiab cov leeg mob plab.
- Yog koj muaj cov tsos mob no, nrog koj tus kws kho mob tham txog lawv. Nws yog ib qho tseem ceeb uas yuav tsum tsis txhob ntshai.
- Nyob ntawm seb ua rau muaj qhov teeb meem no, tus mob no kho tau zoo los ntawm kev phais, tshuaj, thiab kev hloov pauv hauv lub neej.
Hyperaldosteronism, ntshav siab, qog adrenal, aldosterone, potassium qis, siab, Conn's syndrome
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus