Lɛ wi lan bɔt Angiotensin, we de kɔntrol yu blɔd prɛshɔn.

Yu dɔn ɛva gɛt prɔblɛm wit yu blɔd prɛshɔn? Sɔntɛm dɔktɔ dɔn tɔk bɔt wan wɔd lɛk Angiotensin we i de tɔk bɔt yu blɔd prɛshɔn. Wetin na dis angiotensin rili? Aw i impɔtant to wi bɔdi? Lɛ wi tɔk bɔt am jɔs tide.

Wetin rili na Angiotensin?

Fɔ tɔk am simpul wan, angiotensin na ɔmon we de na wi bɔdi. Ɔmon dɛn tan lɛk mɛsenja dɛn we de rɔn rawnd wi bɔdi. Dɛn kin travul tru di blɔd ɛn tɛl difrɛn ɔgan dɛn, mɔsul dɛn, ɛn tisu dɛn wetin fɔ du ɛn ustɛm fɔ du am. So dis ɔmon we dɛn kɔl angiotensin de kɔntrol wi blɔd prɛshɔn mɔ ɛn i de mek di wata ɛn sɔl (espɛshali sɔdiɔm) we de na wi bɔdi fayn. I de du dis bay we i de kɔnstrikt ɔ smɔl di blɔd vesel dɛn ɛn ɛp di bɔdi fɔ tek wata ɛn sɔl.

Fɔ difrɛn kayn angiotensin de. Dɛn kɔl dɛn bay Roman nɔmba dɛn: Angiotensin I, II, III, IV. Fɔ dɛn wan ya , Angiotensin II na di men ɔmon we de wok pas ɔl. I tan lɛk di kapten fɔ di tim. If di amount of dis angiotensin na wi bodi de dכn כ inkrεs, i kin afekt wi hεlth. So, fɔ balans dis rili impɔtant.

Sɔntɛnde, dɔktɔ dɛn kin gi wan angiotensin II we dɛn mek wit atifishal wan, we dɛn kin gi big pipul dɛn insay dɛn bɛlɛ (IV), fɔ mek blɔd prɛshɔn kam bak to nɔmal, mɔ we i gɛt siriɔs kes lɛk sɛptik shɔk, usay blɔd prɛshɔn dɔn go dɔŋ tumɔs.

Wetin Angiotensin II de du to di bɔdi?

Angiotensin II na wan ɔmon we rili de wok. I kin travul go na bɔku say dɛn na wi bɔdi ɛn du bɔku tin dɛn. Bɔt di men tin dɛn we i kin du na fɔ mek di blɔd bɔku, fɔ mek di blɔd prɛshɔn go ɔp, ɛn fɔ mek di sodium (sɔl) bɔku. Dis kin apin lɛk dis:

• Yu adrenal gland dɛn kin mek dɛn pul ɔda ɔmon we dɛn kɔl aldosterone . dis aldosterone de mek di bכdi de kip sכdiכm, bכt potashכm de kכmכt na di urine.
• i de mek di bכdi prεshכn go כp bay we i de kכnstrikt di wכl dεm na di sכm sכm atεri dεm (arterioles). Tink bɔt am lɛk fɔ swɛt wata paip ɛn mek di wata flɔ fast.
• I kin afɛkt di haypothalamus na yu bren, ɛn dis kin mek yu tɔsti. Dɔn yu de drink wata.
• I de tɔk bak to di haypothalamus, we de mek yu want sɔl.
• di pituitary gland de ɛp fɔ pul di antidiuretic hormone (ADH), we dɛn kin kɔl bak vasopressin . dis ADH de mek di kidni dεm de tek mכr wata bak insay di bכdi, we de mek di wata we de insay di bכdi go כp.

Fɔ tɔk am simpul wan, angiotensin II na di men tin we de mek di blɔd prɛshɔn go ɔp ɛn mek di sɔl ɛn wata we de na di bɔdi go ɔp.

Aw dɛn kin kɔntrol dɛn angiotensin lɛvɛl ya?

dis na wan sistεm we rili kכmpleks, lεk wan siriכs mεkanism dεm we kכnεkt inta kכnekt. Dɛn kɔl am di Renin-Angiotensin-Aldosterone System (RAAS) . Dis na di men sistɛm we de ɛp fɔ kɔntrol wi blɔd prɛshɔn.

Imajin, dis na aw i bigin:

1. Fɔs, we yu blɔd prɛshɔn go dɔŋ , yu kidni dɛn kin pul wan ɛnzaym we dɛn kɔl renin insay yu blɔd. Enzym na tin dɛm we de mek kemikal riakshɔn kwik kwik wan.

2. Dis renin de brok dכn wan protin we dεn kכl angiotensinogen , we dεn mek na di liva. Dɔn wan pat pan am kin kɔmɔt, we na di ɔmon we dɛn kɔl angiotensin I. Bɔt dis angiotensin I nɔ de wok, we min se i nɔ kin ebul fɔ gɛt big ifɛkt fɔ insɛf.

3. afta dat, as dis angiotensin I de sכkכt insay di bכdi, i de brok dכn bay כda εnzym we dεn kכ l angiotensin-converting enzyme (ACE) insay di lכng εn kidni dεm. Na da tɛm de aktiv angiotensin II de fɔm.

Naw dis nyu angiotensin II we dɛn dɔn mek de kam insay:

• i de mek di wכl dεm na di sכm atεri dεm (arterioles) kכnstrikt εn i de mek di bכdi prεshכn go כp.
• כlso, dεn tεl di adrenal gland dεm fכ rilis aldosterone, εn dεn tεl di pituitary gland fכ rilis ADH (vasopressin).

dis aldosterone εn ADH tכgeda de fכs di kidni dεm fכ kip sכdiכm (sכlt) na di bכdi. Aldosterone de mek potashכm kכmכt na di urine. We di sodium lɛvɛl na di blɔd go ɔp, di bɔdi kin kip wata bak. Dis kin mek di blɔd bɔku ɛn di blɔd prɛshɔn go ɔp. na we di renin-angiotensin-aldosterone sistεm de kכmplit. Yu ɔndastand dis saykl?

di RAAS sistεm kin wok bak bay כda כmon dεm lεk kכ tikostεroyd, εstrojen, εn tayroyd כmon dεm . If prɔblɛm de wit ɛni pat pan dis sistɛm, i kin afɛkt yu blɔd prɛshɔn, sɔdiɔm, ɛn potashɔm lɛvɛl. Bɔt bɔku ɔda tin dɛn de we kin afɛkt blɔd prɛshɔn lɛk ay kɔlɔstrel, jɛnɛtiks, ɛn sɔm mɛrɛsin dɛn.

Wetin kin apin if di angiotensin lɛvɛl go dɔŋ?

If di angiotensin II lɛvɛl smɔl pas aw i fɔ bi (dɛn kin kɔl am bak angiotensin deficiency ), dɛn prɔblɛm ya kin apin:

• Lɔw blɔd prɛshɔn (haypɔtɛnshɔn) .
• di potashכm lεvεl dεm we de go כp (hyperkalemia) .
• di sodium lεvεl dεm we de dכn (hyponatremia) .
• Fluid (wata) we de kכmכt pasmak wit urine.

Wetin na di sayn dɛm wae de sho se yu blɔd prɛshɔn dɔn dɔŋ?

Yu kin fil tin dɛn lɛk:

• Diziz, layt ed, ɛn sɔntɛm i kin fɔdɔm.
• Di vishɔn we nɔ klia.
• Vɔmit.
• Wok tranga wan.

Di sayn dɛn we de sho se pɔsin gɛt bɔku potashɔm (Hyperkalemia) .

If di potashכm lεvεl na di bכdi inkrεs, dεn tin ya kin apin:

• Bɛlɛ de at ɛn dayarɛa.
• Chɛst de pen.
• At nɔ kin bit ɔltɛm ɔ i kin bit kwik kwik wan (arithmia).
• di mכsul dεm wik כ di limb dεm we de sכmtεm sכmtεm.
• Nɔs ɛn vɔmit.

Di sayn dɛn we de sho se pɔsin nɔ gɛt bɛtɛ sodium (Hyponatremia) .

If di sodium lɛvɛl na di bɔdi go dɔŋ, di sayn dɛm lɛk:

• Mɔsul dɛn kin pen ɔ wikɛd.
• Nɔs ɛn vɔmit.
• Letargy, we pɔsin nɔ gɛt ɛnaji.
• Ɛd we de at ɛn kɔnfyushɔn.
• Epileptic seizures we pɔsin kin gɛt.

If yu gɛt sɔm kayn sik lɛk dis, i rili impɔtant fɔ tɔk to dɔktɔ fɔ tru.

Wetin kin apin if di angiotensin lɛvɛl go ɔp?

naw lε wi luk wetin kin apin we di angiotensin II lεvεl dεm hכy pas nכmal. If dis apin, di bɔdi kin kip wata we nɔ nid (wata) ɛn di blɔd prɛshɔn kin go ɔp (haypa prɛshɔn). Bɔrku tɛm dɛn kin si dis sik pan pipul dɛm wae gɛt at pwɛl hat . Sayɛnsman dɛn biliv se we pɔsin gɛt bɔku angiotensin, dat kin ɛp bak fɔ mek di at big.

Bɔt gud tin na dat, dɔktɔ dɛn kin gi dɛn mɛrɛsin fɔ trit pipul dɛn we gɛt ay angiotensin II. di wan dεm we kכmכn pas כl na di ACE inhibito dεm (lεk enalapril) εn angiotensin rεsεptכr blכk dεm (ARB) (lεk losartan) . Bɔt lɛk bɔku mɛrɛsin dɛn, dɛn mɛrɛsin ya kin gɛt bad bad tin dɛn. sכmtεm dεn kin mek di potashכm lεvεl dεm na di bכdi (hyperkalemia). I impɔtant fɔ tek yu mɛrɛsin jɔs lɛk aw yu dɔktɔ tɛl yu fɔ tek am ɛn fɔ de chɛk yu ɔltɛm.

Fɔ dɔn, tin dɛn we wi fɔ mɛmba

So, naw yu ɔndastand aw dis ɔmon we dɛn kɔl angiotensin impɔtant fɔ kɔntrol wi blɔd prɛshɔn. I tan lɛk dilikɛt balans, tumɔs smɔl na prɔblɛm, tumɔs na prɔblɛm.

I impɔtant fɔ kip yu blɔd prɛshɔn na wɛlbɔdi lɛvɛl. Dɔn bak, if yu gɛt prɔblɛm fɔ kɔntrol yu blɔd prɛshɔn bikɔs ɔf di chenj dɛn we de na yu sɔl (sɔdiɔm) lɛvɛl, i fayn fɔ tɔk to yu dɔktɔ bɔt yu angiotensin lɛvɛl. Dɔn dɛn kin du tɛst fɔ si if yu sik na bikɔs ɔf di ɔmon we nɔ balans.

Mɛmba se, nɔ ɛva stɔp ɔ bigin fɔ tek mɛrɛsin we yu nɔ aks dɔktɔ.Du ɔltin akɔdin to di advays we dɔktɔ gi. Dɔn yu kin kɔntinyu fɔ gɛt wɛlbɔdi.

` Angiotensin, blɔd prɛshɔn, ɔmon, renin, aldosterone, ACE inhibito, haypatɛnshɔn, haypɔtɛnshɔn