Yu kin gɛt prɔblɛm bak fɔ blo lɛk asma? Dɛn kayn tɛm dɛn de, di dɔktɔ go dɔn tɛl yu fɔ yuz inhala. Beta-agonist na spɛshal kayn mɛrɛsin we de insay dɛn inhala dɛn de we de mek wi ebul fɔ blo izi wan. Pan ɔl we dis nem kɔmplikt smɔl, di wok we dɛn tin ya de du rili simpul. Lɛ wi tɔk bɔt dis smɔl mɔ, rili simpul.
Fɔ tɔk am simpul wan, wetin na beta-agonist?
Tink bɔt di sɛl dɛn na wi bɔdi lɛk se dɛn gɛt smɔl ‘swit’ ɔ ‘bɔt’. Insay mεdikal, wi kin kכl dεn rεsεpכta dεm ya. dis kayn mεdikeshכn we dεn kכl beta-agonist de tכn dεn ‘switch' dεm we dεn kכl beta-rεsεptor dεm na wi lכng εn כda כgan dεm.
we dεn on dis switch, di mכsul dεm we de rawnd di aywe dεm na di lכng dεm de rilaks. Dis kin mek di say dɛn we wi kin blo we dɔn smɔl, opin ɛn i kin mek i izi fɔ wi fɔ blo. Na dat mek dɛn kin kɔl dɛn mɛrɛsin ya bak ‘bronchodilators’. Apat frɔm dat, dɛn kin ɛp fɔ mek di at bit mɔ ɛn mɔ ɛn mek di at wok go ɔp te to sɔm mak.
Men kayn beta-agonist dɛn de?
Yɛs, dɛn kin sheb dɛn mɛrɛsin ya bak to tri men kategori, i kin dipen pan di kayn beta-rɛsɛptɔ dɛn na wi bɔdi.
- Beta-1 agonists: Dɛn wan ya kin mɔs afɛkt di riseptɔ dɛn na wi at . Dis kayn mɛrɛsin de mek di at bit fast ɛn ɛp am fɔ pɔmp blɔd wit mɔ pawa. Na dat mek dɔktɔ dɛn kin yuz dɛn pan sɔm at sik ɛn imejensi.
- Beta-2 agonists: Dis na di kayn we we dɛn kin yuz mɔ. Dɛn mɛrɛsin ya, mɔ di wan dɛn we dɛn kin gi wit inhala, kin wok bay we dɛn kin tay dairekt wan to di riseptɔ dɛn na di lɔng , we kin mek di mɔsul dɛn we de na di say dɛn we di briz de blo rilaks ɛn mek i izi fɔ blo. Dɛn impɔtant fɔ trit tin dɛn lɛk asma ɛn COPD (Chronic Obstructive Pulmonary Disease).
- Beta-3 agonists: Dis na nyu klas fɔ mɛrɛsin. Di mɛrɛsin dɛn we de naw na dis klas kin wok mɔ bay we dɛn de rilaks di mɔsul dɛn na di blad , ɛn dis kin mek i nɔ nid fɔ pis bɔku tɛm. Dis min se dɛn kin yuz dɛn fɔ trit wan sik we dɛn kɔl ɔvaaktiv blad.
di kayn beta-2 agonist dεm de bak.
Yes, dis beta-2 tכp we dεn gi fכ difεlεns fכ brith dεn sheb am bak to tu pat. I rili impɔtant fɔ mek yu no dis.
| Tayp fɔ mɛrɛsin | Tɔk bɔt |
|---|---|
| Beta-Agonist dɛn we de wok fɔ shɔt tɛm (SABA) . | Dɛn kɔl dɛn tin ya "rescue inhalers." Dɛn kin yuse dɛn wae asma atak kin wɔs wan wan ɔr wae yu nɔr kin ebul fɔ blo. Dɛn kin wok insay sɔm minit dɛn ɛn dɛn kin mek dɛn fil fri kwik kwik wan. |
| Beta-Agonist dɛn we de wok fɔ lɔng tɛm (LABA) . | Dɛn tin ya nɔto fɔ mek pɔsin fil fayn kwik kwik wan. Dɛn kin yuse dɛn ɛvride, ɔltɛm, fɔ kɔntrol di sayn dɛm ɛn fɔ mek i nɔ izi fɔ blo. Di tin dɛn we dɛn kin du kin las fɔ sɔm awa. Dɛn kin gi dɛn togɛda wit wan stɛroyd (kɔtikosterɔyd) mɛrɛsin. |
Aw dis mɛrɛsin de wok insay di bɔdi?
di bεst we fכ כndastand dis na fכ tink bכt wi bכdi in "fεt-כ-flay" rispכns. Imajin se yu de kam fɔ gɛt wan denja wantɛm wantɛm. Da tɛm de, yu bɔdi kin rɛdi fɔ fɛt ɔ rɔnawe.
Dis tεm ya, signal dεm de kכmכt frכm di bren, we de mek di aywe dεm na di lכng dεm big fכ tek mכr כksijεn, εn i de mek di at rεt kwik fכ sεnd da blכd de we gεt כksijεn to di mכsul dεm kwik kwik wan.
Na dat na di rayt tin we beta-agonist mɛrɛsin dɛn kin du artificially. Dɛn kin on di rayt ‘swit’ (risɛptɔ) dɛn ɛn mek di bɔdi ansa lɛk se i de fes imejensi. Na dat mek di mɔsul dɛn na di lɔng dɛn kin rilaks, ɛn dis kin mek i izi fɔ blo.
Wetin na di beta-agonist drɔgs dɛn we dɛn kin yuz mɔ?
Difrɛn kayn beta-agonist mɛrɛsin dɛn de we dɔktɔ dɛn kin gi. Na sɔm ɛgzampul dɛn ya:
| Kategori fɔ drɔgs | Ɛgzampul dɛn (drɔg nem dɛn) . |
|---|---|
| Beta-2 we de wok shɔt (SABA) . | Salbutamol / Albuterol, Levalbuterol, ɛn ɔda pipul dɛn |
| Beta-2 we de wok fɔ lɔng tɛm (LABA) . | Fɔmoterol, Salmɛtɛrɔl, Indakatɔl |
| Beta-1 agonist we gɛt di sik | Dobutamin, Nɔrɛpinɛfrin |
| Beta-3 agonist we gɛt di sik | Mirabegron we dɛn kɔl |
Ɛni sayd ɛfɛkt de fɔ dis mɛrɛsin?
Lɛk ɛni mɛrɛsin, beta-agonist kin mek sɔm pipul dɛn gɛt sayd ɛfɛkt. Bɔt we dɛn yuz am as inhala, di mɛrɛsin kin go dairekt na di lɔng, so di sayd ɛfɛkt dɛn nɔ kin rili bad. Bɔt sɔm pipul dɛn kin gɛt:
- At bit kwik kwik wan (Tachycardia) .
- At we nɔ de bit ɔltɛm (Aritmia) .
- Shakiness we pɔsin kin shek
- Wɔri
- Ɛd we de at
- Mɔsul dɛn we kin kramp
- We pɔsin de swet
Di tin we impɔtant pas ɔl na dat if yu gɛt ɛni wan pan dɛn bad bad tin ya, ɔ if yu fil ɛnitin we nɔ kɔmɔn afta yu dɔn yuz di mɛrɛsin, tɔk to yu dɔktɔ wantɛm wantɛm. I kin ebul fɔ ajɔst di doz ɔ gi yu difrɛn mɛrɛsin.
Ustɛm yu fɔ go to dɔktɔ?
Bɔku tin dɛn de we kin rili impɔtant fɔ go to yu dɔktɔ.
- If yu gɛt bad bad tin dɛn we nɔ fayn ɛn we yu nɔ bin de ɛkspɛkt .
- If yu fil se yu mɛrɛsin nɔ de wok fayn lɛk aw i bin de wok trade (fɔ ɛgzampul, yu nid fɔ yuz yu inhala pas aw yu bin de yuz am bifo fɔ gɛt rilif).
- If yu fil se yu sik de kam wɔs ɛn yu nɔr ebul fɔ kɔntrol dɛn .
If na so i bi, yu dɔktɔ kin rivyu yu tritmɛnt plan ɛn gi yu di sɔlv we go mek yu fil fayn ɛn we go wok fayn.Nɔ ɛva stɔp fɔ tek yu mɛrɛsin ɔ chenj di doz if yu nɔ gɛt dɔktɔ advays. If yu gɛt ɛni bad bad sayd ɛfɛkt, go na di ɔspitul Imejɛnsi Dipatmɛnt (ETU) we de nia yu wantɛm wantɛm.
Mɛsej we dɛn kin kɛr go na os
- Beta-agonist na wan kayn mɛrɛsin we de mek i izi fɔ blo, dɛn kin yuz am mɔ fɔ sik dɛn we pɔsin kin gɛt we i de blo lɛk asma ɛn COPD.
- Tu men kayn dεm de: sכt-akt (SABA) we de gi kwik rilif we imejensi, εn lכng-akt (LABA) we de gi lכng tεm kכntrכl pan di sik.
- Yuz dis mɛrɛsin ɔltɛm jɔs lɛk aw yu dɔktɔ tɛl yu fɔ yuz, ɛn na di doz we dɛn tɛl yu fɔ yuz nɔmɔ .
- Yu fɔ no bɔt di sayd ɛfɛkt dɛm lɛk we yu at de bit kwik kwik wan ɛn yu an we de shek shek. If yu gɛt ɛni prɔblɛm, tɛl yu dɔktɔ wantɛm wantɛm.
- If yu fil se yu tritmɛnt nɔr de woke fayn ɔr de sik wae yu de fil de wɔs, nɔr de trit yusɛf ɛn go to dɔktɔ.
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