Yu de fil se yu tan ɛn yu nɔ gɛt layf? Lɛ wi lan bɔt Cachexia (Wasting Syndrome)!

Sɔntɛnde, yu kin tink se, ‘O, wetin mek a tan lɛk? A nɔ ebul ivin it. A kin taya so ɔl di de.’ Ɔ yu dɔn si pɔsin we de nia yu de sɔfa wit dis sik? Infakt, wan kayn tin de wae kin mek pɔrsin fil bad wae kin apun wit sɔm kayn bad bad sik wae kin teik lɔng tɛm. Dɔktɔ dɛn kɔl am Cachexia ɔ Wasting Syndrome . Dis na rili wan sik we de afɛkt lɛk 9 milyɔn pipul dɛn ɔlsay na di wɔl. Fɔ tɔk am simpul wan, i kin mek di bɔdi west smɔl smɔl. Di nem kɔmɔt frɔm tu Grik wɔd dɛn, "kakos" (bad) ɛn "hexis" (kɔndishɔn). So, "bad bɔdi kɔndishɔn" na wetin i min. Dis nɔto izi tin fɔ du, bɔt lɛ wi tɔk bɔt am ditayli, bikɔs i rili impɔtant fɔ no bɔt am.

Wetin na di sayn dɛm fɔ Cachexia?

Dɔktɔ kin yuz di wɔd "cachectic" we dɛn de tɔk bɔt dis kɔndishɔn. Si if yu ɔ pɔrsin wae yu sabi gɛt dɛn sik ya:

• We yu nɔr ɛksplen to yu wet: Dis na di men sayn. Yu kin kɔntinyu fɔ lɛf fɔ it bɔku bɔku it dɛn, ilɛksɛf yu nɔ de tray fɔ lɛf fɔ it bɔku bɔku it dɛn ɛn yu de it tin dɛn we go mek yu gɛt wɛlbɔdi. Bɔku tɛm, if yu lɔs 5% ɔ mɔ pan yu ɔl yu wet insay 6 to 12 mɔnt, dɔktɔ dɛn kin sɔprayz. Fɔ ɛgzampul, if yu wet 60 kilo, if yu lɔs 3 kilo ɔ mɔ kin bi sayn fɔ dis.
• Mɔsul dɛn we de lɔs: Dɔktɔ dɛn kin kɔl dis bak fɔ west mɔsul ɔ fɔ mek di mɔsul dɛn nɔ de wok fayn . Fɔ tɔk am simpul wan, smɔl smɔl di mɔsul dɛn na yu bɔdi kin lɔs dɛn trɛnk. Dɛn kin smɔl ɛn wik. Yu go si se ivin wok dɛn we bin izi bifo, i kin tan lɛk se i nɔ izi fɔ du.
• Taya ɛn wik: Dis nɔto jɔs nɔmal taya. Yu kin fil so taya ɔl di de dat yu nɔ ebul fɔ du natin. Sɔntɛm yu nɔ go ivin fil fɔ grap na bed.
• Anorexia (we yu nɔ want fɔ it): I nɔ de want fɔ it. Fɔd nɔ de si igen ɛn i nɔ de te. Dis difrɛn frɔm di sik we dɛn kɔl Anorexia Nervosa . Dis na tin wae de pɔrsin nɔr kin want fɔ it bikɔs ɔf de sik.

Wetin mek Cachexia kin apin?

Fɔ tɔk am simpul wan, kachexia kin apin we di rilayshɔn bitwin di ɛnaji we wi bɔdi de aks fɔ ɛn di ɛnaji we wi kin gɛt frɔm it kin ambɔg. De men rizin fɔ dis na wae pɔrsin gɛt siriɔs sik wae nɔr de dɔn, lɛk kansa, ɔr at sik.

Imajin, we yu gɛt siriɔs sik, yu imyun sistɛm bigin fɔ fɛt da sik de. Dɔn di tin dɛn we yu bɔdi de du kin mek yu bɔdi wok kwik kwik wan. Dat min se yu bɔdi nid mɔ ɛnaji pas aw i kin gɛt. Bɔt, bikɔs ɔf da sik de, yu nɔ kin want fɔ it bak.

So, we yu nɔ gɛt inof ɛnaji frɔm it, wetin yu bɔdi de du? I kin bigin fɔ pul ɛnaji frɔm yu mɔsul dɛn ɛn di fat we yu dɔn put. Na dat mek yu de lɔs yu wet ɛn yu mɔsul dɛn de mɛlt.

Fɔ put am smɔl mɔ pan sayɛns, sɔm patikyula rizin dɛn de we de afɛkt dis:

• di Saytokin dεm we de inkrεs: Saytokin dεm na spεshal protin dεm na wi imyun sistεm. Dɛn tin ya kin ɛp wi bɔdi fɔ fɛt di tin dɛn we kin kam insay wi lɛk vayrɔs. כltu, insay Cachexia, dεn saytokεn dεm ya de inkrεs tumɔs εn de mek inflameshn ɔlsay na di bכdi. Dis kin mek di fat ɛn mɔsul dɛn lɔs.
• Inflameshɔn we de ɔlsay na di sistɛm: Dis inflamɛns we sik dɛn we nɔ de mɛn lɛk kansa kin mek bak di fat ɛn mɔsul dɛn west.
• Insulin resistance: Insulin na ɔmon we de kɔntrol di blɔd shuga na wi bɔdi. Insulin rεsistεns min se wi mכsul εn fεt sεl dεm nכ de rεspכnd fayn to insulin. Insay kachexia, dis kכndyushכn kin mek di mכsul dεm west mכr.
• di protin dεm we de tכn bכku bכku wan: wan prכsεs de insay wi sεl dεm usay dεn de mek nyu protin dεm fכ tek ol protin dεm in ples. Dɛn kin kɔl dis bak di prɔtin dɛgradɛshɔn . insay kεshεksia, di rεt we dεn protin dεm ya de brok dכn de inkrεs fast pas di rεt we dεn de mek nyu wan dεm. Dis min se di bɔdi de yuz mɔ prɔtin pas aw i de mek nyu wan dɛn. Dis na di men tin bak we kin mek di mɔsul dɛn lɔs.

Us kɔndishɔn dɛn kin gɛt fɔ du wit Cachexia?

Dɛn kin si cachexia mɔ pan pipul dɛn we gɛt kansa . Stɔdi dɔn sho se lɛk 40% pan di wan dɛn we gɛt kansa gɛt kashɛksia we dɛn fɔs no di sik, ɛn lɛk 70% pan di wan dɛn we gɛt kansa we dɔn go bifo ɔ we dɔn let kin gɛt kashɛksia.

Bɔt dis sik nɔ kin apin to pipul dɛn nɔmɔ we gɛt kansa, bɔt i kin apin bak to pipul dɛn we gɛt ɔda siriɔs sik dɛn we nɔ de mɛn. Na sɔm ɛgzampul dɛn ya:

• Konjestiv hat fεil: Bitwin 16% εn 42% pan di pipul dεm we gεt at fεil kin gεt kadyak kεshεksia.
• Kronik ɔbstrɔktiv pulmonari sik (COPD): Cachexia kin kam pan 27% to 35% pan pipul dɛm wae gɛt COPD.
• Krכnik kidni sik (CKD): Dis kכndyushכn kin afekt bitwin 30% εn 60% pan pipul dεm wae gεt CKD.
• Sɔm sik dɛn we pɔsin kin gɛt: Fɔ ɛgzampul, AIDS (Acquired Immune Deficiency Syndrome) .Cachexia na kɔmɔn tin as di sik de go bifo. I kin kam bak pan pipul dɛm wae gɛt sik dɛm lɛk TB ɛn malaria.
• Krכnik inflammatory diseases: Bitwin 18% εn 67% pan di pipul dεm wae gεt inflammatory joint kondishכn, lεk rεumatoid arthritis , kin gεt cachexia.

Wetin na di kɔmplikɛshɔn dɛm wae de kam wit kashɛksia?

Cachexia na wan sik wae kin mek pɔrsin in layf de pan denja. Tink bɔt dis, Cachexia na in de mek 20% pan di wan dɛn we de day pan kansa. Bikɔs we i de mek di mɔsul dɛn west, i kin afɛkt di at ɛn di we aw wi de blo.

Bɔrku tɛm, if dɛn no se yu gɛt kashɛksia, dat min se di ɛnd pan layf dɔn nia. Dis na nyus we at fɔ yɛri, fɔ di pɔsin we sik ɛn fɔ di wan dɛn we dɛn lɛk. E kin mek bak yu gɛt prɔblɛm wit yu maynd lɛk fɔ wɔri ɛn pwɛl hat.

We kashɛksia kin mek yu nɔ gɛt bɔku bɔku bɔdi ɛn yu kin chenj di we aw yu de luk, sɔm pipul dɛn kin shem ɛn wɔri. I kin rili sɔri bak we yu nɔ ebul fɔ du yu yon wok bikɔs yu bɔdi wik.

Risach dɔn sho se sɔm tin wae nɔr kin fayn kin de bitwin di pɔrsin wae gɛt cachexia ɛn di wan dɛm wae de kia fɔ dɛn. Imajin aw i nɔ kin izi fɔ wach di pɔsin we yu lɛk kin tan lɛk pɔsin we tan lɛk pɔsin, we kin wik, ɛn we i nɔ kin ebul fɔ du wetin i want. Sɔntɛnde, di wan dɛn we de kia fɔ dɛn kin tink se, "If a jɔs gi dɛn smɔl mɔ it, a go ebul fɔ kɔntrol dis." Bɔt we di pɔsin we sik nɔ gri fɔ it, dɛn kin fil bad ɛn vɛks. Dis prɛshɔn fɔ it kin mek ivin famili mitin nɔ fayn. Sɔm pasɛnt dɛn kin mek lɛk se dɛn de slip we di gɔst dɛn kam, dɛn kin op se dɛn go fos dɛn fɔ it.

Aw dɛn kin no se pɔsin gɛt Cachexia?

Di fɔs tin we dɔktɔ go du na fɔ chɛk yu bɔdi. Dɛn go aks bɔt yu jenɛral wɛlbɔdi, ɛni ɔda mɛrɛsin we yu gɛt, mɔ if yu de tek ɛni mɛrɛsin we nɔ de mɛn we go de mek yu gɛt cachexia. Dɛn kin du tɛst bak fɔ chɛk yu bɔdi ɛn yu mɔsul dɛn trɛnk. Dɛn kin du blɔd tɛst bak, lɛk Comprehensive Metabolic Panel (CMP) , ɛn CT (Computed Tomography) skan .

Aw dɛn kin trit Cachexia?

Infakt, no patikyula tritmɛnt nɔ de fɔ cachexia yet. Dɔktɔ dɛn kin pe atɛnshɔn mɔ fɔ trit di ɔndalayn kɔndishɔn we mek pɔsin gɛt kashɛksia. Dat min se fɔ trit di kansa, at sik, ɔ ɔda sik we nɔ de mɛn na di tin we impɔtant pas ɔl.

Apat frɔm dat, we yu want fɔ it, dɛn kin tɛl yu aw fɔ mek yu it mɔ.

Fɔ ɛgzampul, dɔktɔ dɛn kin se yu fɔ it tin dɛn we gɛt bɔku prɔtin, fat, ɛn kalori, smɔl smɔl, bɔku tɛm insay di de.Ivin if yu nɔ ebul fɔ it big it wan tɛm, if yu it smɔl smɔl it dɛn bɔku tɛm insay di de, dat go ɛp yu fɔ gɛt mɔ kalori. I fayn fɔ tɔk to yu nyutrishɔnist bɔt us it dɛn we fit fɔ dis tɛm pan di ia ɛn aw yu go yuz ɛvri bayt we yu it fayn fayn wan.

Yu tink se mɛrɛsin de fɔ mek pɔsin gɛt cachexia?

Naw, nɔr patikyula mɛrɛsin nɔr de we dɛn dɔn gri fɔ fɔ mek dɛn gɛt cachexia. Pan ɔl we sɔm risach dɔn sho se di mɛrɛsin we dɛn kɔl megestrol acetate kin mek pɔsin want fɔ it mɔ ɛn mek i gɛt sɔm wet, di US Food and Drug Administration (FDA) nɔ gri fɔ am yet as tritmɛnt fɔ cachexia we kansa kin mek. Sɔntɛnde, dɔktɔ dɛn kin gi yu mɛrɛsin lɛk kɔtikosterɔyd fɔ shɔt tɛm.

Wetin di wan dɛn we de kia fɔ dɛn kin du?

If yu de kia fɔ pɔrsin wae gɛt cachexia, i impɔtant fɔ mɛmba dis: We cachexia kam bikɔs ɔf siriɔs sik, di bɔdi in mɛtabolism kin spid, so di sik pipul dɛm nɔ kin fil angri. Na dat mek, ivin if yu gi dɛn mɔ kalori , di kayn sik we dɛn kɔl cachexia nɔ kin bɛtɛ ɔltɛm. fכs -fid כnli de inkrεs di simptom dεm lεk nכs εn vכmit. Dis kin mek di pɔsin we sik nɔ kin fil fayn mɔ ɛn mɔ.

So, bifo yu fos di pɔsin we yu lɛk fɔ it, tink bɔt ɔda we dɛn fɔ kɔrej dɛn. Fɔ ɛgzampul, smɔl smɔl tin dɛn lɛk fɔ masaj dɛn wan wan tɛm, fɔ put sɔm loshan na dɛn bɔdi, ɔ fɔ put mɔstizayza na dɛn lip if dɛn dray kin rili kɔrej dɛn. I rili impɔtant bak fɔ mek yu tɔk to dɛn ɛn lisin to dɛn.

If a gɛt Cachexia, wetin a fɔ ɛkspɛkt?

If yu gɛt dis sik, yu go dɔn ɔlrɛdi de sɔfa wit siriɔs sik, we go mek yu nɔ ebul fɔ kil am. Dipen pan yu sik, if yu no se yu gɛt cachexia, dat kin min se yu dɔn nia fɔ dɔn yu layf. Bɔt bikɔs bɔku tin dɛn de we kin mek pɔsin gɛt kes, yu sik kin rili difrɛn frɔm ɔda pɔsin in yon. So, di bɛst we fɔ no wetin fɔ ɛkspɛkt na fɔ tɔk to yu wɛlbɔdi tim. Bi opin wan wit dɛn.

Aw a kin kia fɔ misɛf?

Pan ɔl we no definitiv gayd nɔr de fɔ liv wit cachexia, dɛn advays ya kin ɛp yu:

• It fayn (bɔt nɔ fɔ fos): It we yu fil se yu want fɔ it. Bɔt nɔ fos yusɛf fɔ it bikɔs yu rili nid fɔ it.
• Tray fɔ it smɔl smɔl tin dɛn: We yu de fil strɛs, yu nɔ go fil fɔ it big it. So, tray fɔ it smɔl smɔl it dɛn we gɛt bɔku kalori bɔku tɛm insay di de. Tɔk to yu nyutrishɔnist bɔt aw fɔ it.
• Du layt ɛksɛsayz:If i pɔsibul, fɔ du ɛksesaiz we rili layt, dat kin ɛp fɔ mek yu mɔsul dɛn strɔng. Ivin fɔ jɔs waka ɔ muv yu an ɛn leg smɔl go du.
• Gɛt mɛntɛl hεlth sɔpɔt: E kin kɔmɔn fɔ mek pipul dɛm wae gɛt siriɔs sik lɛk dis kin gɛt strɛs ɛn pwɛl hat. So, nɔ ɛva shem fɔ aks yu mɛdikal tim fɔ ɛp yu wit dis.
• Tink bɔt aw fɔ kia fɔ yu sik: Palliative care na spɛshal tritmɛnt wae de ɛp fɔ kɔntrol yu sik dɛm ɛn di sayd ɛfɛkt dɛm wae de kam wit tritmɛnt.
• Aks bɔt hospice sɔpɔt: Aks yu mɛdikal tim bɔt hospice sɔpɔt. Dis kin inklud sɔpɔt frɔm pipul dɛn lɛk spiritual advaysa ɛn soshal woka.

Yu tink se fɔ it tiub na tritmɛnt fɔ cachexia?

Dכkta dεm jεnarali nכ kin rεkomεnd fכ it εn di εnteral it fכ kεshεksia, biכs dεn nכ pruv se dεn tritmεnt dεm ya kin impruv kεshεksia כ εksεnd layf.

di tכb fכ it na di administreshכn fכ likwid nyutrishכn tru wan fleksibul tכb we dεn put tru di nos, dεrekt insay di bεlε, כ insay di sכmכl intestin. parenteral nyutrishכn na di administreshכn fכ nyutrishכn dεn dεn wan dεm dεn wan insay wan vein tru wan IV layn.

Fɔ dɔn, wetin fɔ mɛmba (Take-Home Message) .

Cachexia, ɔ Wasting Syndrome, na wan sik wae kin afɛkt pipul dɛm wae gɛt siriɔs sik dɛm wae nɔr de dɔn, mɔr lɛk kansa wae dɔn pasmak ɛn hat sik. Bɔku tɛm, dɛn kin tek am se na wan pan di las tin dɛn we pɔsin kin du na layf. Dis na nyus we rili de mek yu at pwɛl fɔ yɛri, ilɛksɛf yu gɛt cachexia ɔ yu de kia fɔ pɔsin we gɛt dis sik. Yu dɔktɔ dɛn no aw bɔku kachexia kin ambɔg yu ɛvride layf ɛn afɛkt yu maynd wɛlbɔdi. If yu de pan dis kayn tin, nɔr ol ɛnitin ɛn aks fɔ sɔpɔt fɔ yu mɛdikal tim fɔ gɛt mɛntɛl hεlth. Mɛmba se nɔto yu wangren de. Di tin we impɔtant pas ɔl na fɔ no bɔt dis, ɔndastand am, ɛn gɛt di ɛp we yu nid.

` cachexia, wasting syndrome, emaciation, wasting, kansa, sik we nɔ de mɛn, we yu de lɔs yu wet, we yu de west yu mɔsul, it, anorexia