Yu kin gɛt bak Alzaima sik wae kin bigin kwik kwik wan? Lɛ wi lan bɔt am!

Yu kin tink sɔm tɛm se, "O, a de fɔgɛt ɔltin dɛn tɛm ya"? Ɔ yu dɔn notis smɔl chenj dɛn na di mɛmori ɔ di we aw yu padi de biev? Sɔntɛm dɛn tin ya nɔto sɔntin we wi fɔ wɔri bɔt. Bɔt if dɛn tin ya kɔntinyu fɔ apin ivin bifo yu ol, i go fayn fɔ mek yu luk insay am smɔl. We yu yɛri dɛn tin ya, i kin ambɔg yu smɔl, bɔt di tin we impɔtant pas ɔl na fɔ no bɔt dis.

Wetin na Alzaima sik we kin bigin kwik kwik wan?

Fɔ tɔk am simpul wan, Early-Onset Alzheimer’s Disease (EOAD) na wan kayn Alzheimer’s disease wae kin kam pan pipul dɛm wae nɔr rich 65 ia. Sɔntɛnde, dɔktɔ dɛn kin kɔl am young-onset Alzheimer’s disease . Bɔrku tɛm, dɛn sik ya kin fɔs de bitwin 45 ɛn 64 ia.

Alzaima sik na wan sik wae de mek pɔrsin nɔr de fil fayn . Dat min se na sik we de pwɛl ɛn pwɛl di sɛl dɛn na wi bren as tɛm de go. Dis na di men tin wae kin mek pɔrsin gɛt dis maynia sik , wae na wae pɔrsin nɔr kin mɛmba ɛn nɔr kin gɛt bɛtɛ sɛns smɔl smɔl. Bɔt, nɔr rich 1% pan ɔl di wan dɛm wae gɛt Alzaima de sɔfa wit dimɛnshɔn wae kin bigin kwik kwik wan (EOAD).

Fɔs, i nɔ kin izi fɔ yu fɔ no di chenj dɛn we de apin to yusɛf. Bɔt di wan dɛn we de nia yu, lɛk yu fambul ɛn padi dɛn, kin notis chenj dɛn we nɔ klia ɛn we yu nɔ go notis. If yu notis ɛni chenj na yu mɛmori, tinkin, ɔr di wok we yu de du ɛvride, go to dɔktɔ wantɛm wantɛm.

Wetin na de sayn dɛm wae de sho se yu gɛt Alzaima wae kin bigin kwik kwik wan?

De sayn dɛm fɔ Alzaima sik wae bin dɔn de bifo kin rili fiba di wan dɛm wae kin gɛt dis sik wae de kam wit Alzaima. Di men difrɛns na di ej we dɛn sik ya kin bigin fɔ sho. dis kכndyushכn de mek di intellektual abiliti dεm de dכn sכmtεm (progrεsiv kכgnitiv dεklin) . Dis min se as di bren de pwɛl, de sik kin wɔs as tɛm de go.

Fɔs, i nɔ kin izi fɔ yu fɔ no dɛn sayn ya yusɛf. Bɔt di wan dɛn we yu lɛk, we na yu famili, go notis dɛn smɔl smɔl chenj dɛn ya. If yu ɔr pɔrsin wae yu trɔst notis ɛni wan pan dɛn sayn ya fɔ dis maynia sik, e fayn fɔ tɔk to dɔktɔ.

Dis kɔndishɔn (EOAD) nɔr kin afɛkt ɔlman di sem we. Bɔt in jɔnal, i kin afɛkt yu:

• Mɛmba
• Langwej skil dɛm - fɔ tɔk ɛn rayt
• Abiliti fɔ tink gud wan
• Di we aw pɔsin de biev ɛn di pɔsin we i bi
• Spatial awareness - fכ egzampl, כndastandin fכ spεs.

(EOAD) Di sayn dɛm kin bigin fɔ rili smɔl ɛn kin wɔs as tɛm de go. We yu bigin, yu kin notis smɔl chenj dɛn lɛk dɛn wan ya:

• Chenj na yu bihayvya ɔr pɔrsin in pɔrsin (especially wae yu de vɛks pasmak, yu de fil fayn, ɔr de fil bad pas aw yu bin de fil) .(I kin bɔku.) Imajin, sɔmbɔdi we bin de rili kol, naw kin vɛks pan smɔl smɔl tin dɛn.
• I nɔ kin izi fɔ fɛn di rayt wɔd dɛn we yu de tɔk ɔ rayt. I kin tan lɛk se wɔd dɛn nɔ de kɔmɔt na yu mɔt.
• Memori lɔs (fɔ ɛgzampul, fɔgɛt pipul dɛn nem, fes, ɔ tin dɛn we bin apin da tɛm de). Bɔku tɛm yu kin fɔgɛt di shopin list we dɛn tɛl yu fɔ kam wit? Ɔ yu kin fɔgɛt wantɛm wantɛm wetin yu bin de go tɔk we yu de tɔk to yu?
• I at fɔ sɔlv prɔblɛm dɛn we yu go ebul fɔ du izi wan.
• Pan ɔl we dɛn dɔn gi instrɔkshɔn (lɛk fɔ kuk jɔs akɔdin to wan risɛp) , i kin at fɔ pe atɛnshɔn pan wetin fɔ du nɛks ɛn disayd .
• Prɔblɛm wit vishɔn, balans, ɛn kɔdineshɔn (yu kin si se yu de bɔmp wit fɔnicha ɔltɛm ɔ yu de stɔp).

Leta, yu kin notis mɔ bad bad sik dɛn lɛk:

• Fɔgɛt usay yu de ɛn aw yu rich de .
• Di tin we wɔs pas ɔl na we yu nɔ de mɛmba tin (to di say we yu kin ivin fɔgɛt sɔm pat dɛn pan yu mɛmori fɔ lɔng tɛm).
• Sɔspɛkt ɛn nɔ trɔst di wan dɛn we yu lɛk (ivin di wan dɛn we yu se yu sabi gud gud wan).
• Di pat (ɔ kɔmplit) lɔs pan di ebul fɔ tɔk ɛn tɔk to pipul dɛn.

Wetin na de tin wae kin mek pɔrsin gɛt Alzaima wae kin bigin kwik kwik wan?

Di men tin we kin mek pɔsin gɛt Alzaima sik bifo tɛm na we di prɔtin dɛn we nɔ kin de na di bren , spɛshal wan tu kayn prɔtin dɛn we dɛn kɔl amyloid ɛn tau .

Yu no, wi bren gɛt bɔku bɔku nerv sɛl dɛn we dɛn kɔl nyuron . Na dɛn nerve cell ya de ɛp wi fɔ tink, lan, mɛmba, ɛn plan. So, di amyloid protin de stik togeda insay di bren sεl dεm, fכ mek kכlכm dεm we dεn k כl plek . Tau protin dɛn kin tang togɛda, ɛn dɛn kin mek tangle . dis plek dεm εn tangle dεm de mek di nεv sεl dεm nכ de wok fayn fayn wan. Dɛn kin blok di ilɛktrik ɛn kemikal signal dɛn we de pas tru dɛn.

we di amyloid εn tau protin dεm de bכku na di bren, dεn de kil di nεv sεl dεm sכmtεm sכmtεm. Dis na de tin wae kin mek pɔrsin gɛt de pwɛl hat sik wae kin kam wit de sik wae de mɛk pɔrsin gɛt Alzaima sik. di nεv sεl dεm kin bigin fכ day na wan pat na di bren, dεn kin spre to כda pat dεm. Bɔku tɛm, EOAD kin bigin na di pat pan di bren we de kɔntrol wi mɛmori - di hipokampus .

Masta sabi bukman dɛn stil de tray fɔ no wetin mek dɛn prɔtin ya kin bɔku. Risach pipul dεm tink se dis bכku bכku protin dεm kin apin lכng bifo di sayn dεm sho. I kin ivin tek lɛk 10 ia bifo yu bigin fɔ gɛt di sik.

Yu tink se Alzaima we kin bigin kwik kwik wan na jenɛtik?

Yɛs, di sik we dɛn kɔl Alzaima we kin kam bifo tɛm na wan sik we pɔsin kin gɛt frɔm in jɛnɛtiks.I pɔsibul. Dɛn dɔn si se bɔku pan dɛn tin ya (Early-Onset Alzheimer’s disease ) gɛt fɔ du wit di chenj dɛn we de apin na di jɛnɛtiks na di kromozom 1, 14, ɔ 21. Dɔn bak, we pɔsin gɛt wan jin we dɛn kɔl (APOE e4 gene) i kin mek di prɔblɛm bɔku. Bɔt nɔto ɔlman we gɛt di (APOE e4) jin go gɛt Alzaima. Na wan tin nɔmɔ kin mek di prɔblɛm bɔku.

Alzaima sik kin rɔn bak na famili. Dis min se if yu mama ɛn papa ɔ yu brɔda ɛn sista dɛn gɛt dis sik, yu go gɛt dis sik. If tu pan yu brɔda ɛn sista dɛn ɔ yu mama ɛn papa ɔl tu gɛt am, yu risk go ivin pas dat.

Wetin na di tin dɛn we kin mek pɔsin gɛt prɔblɛm?

Risach pipul dɛm stil de stɔdi wetin kin mek di sik wae de kam wit Alzaima bifo dis ej. Sɔm tin dɛn we kin mek pɔsin gɛt dis sik kin bi:

• Fɔ gɛt Alzaima sik na yu fambul dɛm wae de nia yu (mama ɛn papa, brɔda ɛn sista dɛm).
• Envayrɔmɛnt factor dɛm (sɔntin na di envayrɔmɛnt usay yu de liv, woke, ɔr ɔltɛm).
• Sivɛri ed injuri (traumatik bren injuri) .
• Fɔ smok.
• Yu ɔl wɛlbɔdi biznɛs.

Sɔm wɛl bɔdi prɔblɛm kin mek yu gɛt Alzaima, lɛk:

• Di sik we de ambɔg di at ɛn di blɔd
• Shuga
• Daun sindrom wae de kam wit (Trisomy 21) .
• Di ay blɔd prɛshɔn
• Kɔlestɔl we bɔku
• Fat

Wetin na de prɔblɛm wae kin kam wit Alzaima wae kin bigin kwik kwik wan?

De big prɔblɛm wae kin kam wit Alzaima sik wae kin bigin kwik na di damej wae e kin kɔz yu bren. I kin mek yu chenj fɔ ɔltɛm na di we aw yu de tink, di we aw yu de yuz yu bɔdi, ɛn yu abit. As de sik de go bifo, yu kin gɛt prɔblɛm dɛn, sɔm pan dɛn kin mek yu layf de pan denja.

Wi kin si dɛn tin ya as kɔmplikeshɔn:

• Di pwɛl pwɛl we de apin na di ɔl bɔdi wɛlbɔdi.
• Infεkshכn (fכ egzampl , nyumonia כ skin infεkshכn).
• Di sik dɛn we kin mek pɔsin sik .
• I nɔ kin izi fɔ yu fɔ blo.
• I nɔ izi fɔ swɛla.

We yu nɔ ebul fɔ kɔntrol yu bɔdi, yu kin gɛt mɔ risk fɔ:

• Bedsɔr dɛn .
• Di wata we nɔ de na di bɔdi ɔ we i nɔ de it fayn .
• Fɔdɔm, bon dɛn we brok, ɛn ɔda bad bad injuri dɛn.
• Urinary incontinence ɛn bɔdi inkɔntinɛns .
• Tut we kin rɔtin, we kin gɛt kaviti, ɛn ɔda prɔblɛm dɛn we kin apin to yu tit.

Aw dɛn kin no bɔt Alzaima sik we kin bigin kwik kwik wan?

Dɔktɔ dɛn kin no EOAD di sem we aw dɛn kin no bɔt Alzaima sik. Dɛn kin du wan kɔmplit ɛgzam fɔ di bɔdi ɛn wan ɛgzam fɔ di nyurolɔjik.Dɔn, dɛn kin pul ɔda sik dɛn we kin mek pɔsin gɛt di sem kayn prɔblɛm fɔ mɛmba ɛn ɔda sayn dɛn.

Yu dɔktɔ go aks yu kwɛstyɔn fɔ ɔndastand yu wɛlbɔdi ɛn ɛvride layf. Dɛn go tɔk to yu bak bɔt chenj dɛn we yu nɔ go notis, bɔt we pɔsin we de nia yu dɔn notis. Yu dɔktɔ kin aks bɔt:

• Yu ɔl wɛlbɔdi biznɛs.
• Yu mɛdikal istri .
• Us mɛrɛsin ɔ supamakit yu de tek naw?
• Di chenj we yu de fil, di we aw yu de biev, ɛn di we aw yu de biev.
• Yu ebul fɔ du di wok dɛn we yu kin du ɔltɛm.

Di dɔktɔ go du sɔm tɛst dɛn bak lɛk:

• Test dɛn we pɔsin kin gɛt fɔ no .
• CT skan we dɛn kin du .
• Bren MRI skan .
• PET skan fɔ .
• Blɔd tɛst dɛn.
• Test fɔ urine.

Nɔr wan tɛst nɔr de wae kin kɔnfirm ɔr no se yu gɛt Alzaima sik wae kin bigin kwik kwik wan. Bɔt wit di infɔmeshɔn we dɛn kin gɛda frɔm ɛni wan pan dɛn tɛst ya, di dɔktɔ kin pul ɔda tin dɛn we kin mek pɔsin gɛt di sem kayn sik.

Wetin na de tritmɛnt fɔ Alzaima sik wae kin bigin kwik kwik wan?

Yu dɔktɔ go tɛl yu fɔ gi yu tritmɛnt fɔ mek yu nɔr gɛt dis maynia sik , wae na wae yu nɔr de mɛmba ɛn nɔr gɛt sɛns. No mɛrɛsin nɔ de fɔ ɛni kayn sik we dɛn kɔl Alzaima . Bɔt, tritmɛnt kin ɛp fɔ kɔntrol di sayn dɛm ɛn slo fɔ mek di sik go bifo.

Fɔ bigin tritmɛnt kwik kwik wan na di bɛst we fɔ mek yu bren gɛt wɛlbɔdi ɔlsay na yu layf. Bɔt nɔr tritmɛnt wae de naw nɔr kin ebul fɔ rivεs di bren damej ɔr di kɔgnitiv dεklin.

Yu dɔktɔ go mɔs gi yu standad Alzaima tritmɛnt fɔ EOAD. Yu kin nid mɛrɛsin dɛn lɛk dɛn wan ya:

• (Di wan dɛn we de stɔp di cholinesterase) .
• (Dɔnanemab) .
• (Lɛkanɛmab) .
• (NMDA antagonist dɛn) .

Aducanumab na wan rili nyu tritmɛnt fɔ EOAD. Masta sabi bukman dɛn stil de stɔdi am. i de ridyus di amyloid protin we de bil insay di bren.

Mɛrɛsin fɔ kɔntrol sɔm patikyula sayn dɛn

Yu dɔktɔ kin gi yu mɛrɛsin bak fɔ kɔntrol sɔm sayn dɛn. Fɔ ɛgzampul:

• Antidipreshan : Dɛn mɛrɛsin ya kin trit tin lɛk fɔ wɔri, fɔ nɔr de rɛst, fɔ de chenj yu maynd, ɛn fɔ gɛt pwɛl hat.
• (Antipsychotics (neuroleptics)) : Dɛn tin ya kin mek yu gɛt paranoia, yu kin si tin dɛn we yu de si, ɛn yu kin mek yu fil bad.Dɛn kin trit tin dɛn lɛk dat.
• (Antiseizure medications) : Dɛn mɛrɛsin ya kin trit sɔmtɛm wae pɔrsin de fil.

Klinik trial dɛn we dɛn kin du

Sayɛnsman dɛn de du risach ɔltɛm bɔt EOAD ɛn di tritmɛnt dɛn we pɔsin kin gɛt. Aks yu dɔktɔ if ɛni klinik trial de we go ɛp yu. Dis na tɛst ɔr stɔdi wae gɛt fɔ du wit volontia dɛm wae gɛt Alzaima sik wae kin bigin kwik kwik wan. Dɛn tin ya kin gi yu chans fɔ tray nyu tritmɛnt dɛn we nɔ de yet fɔ bɔku pipul dɛn.

Wetin na de pɔrsin wae gɛt Alzaima wae kin bigin fɔ liv kwik kwik wan kin liv?

Di sik we dɛn kɔl Alzaima we kin kam bifo tɛm kin afɛkt ɔlman difrɛn we. Sɔm pipul dɛn de liv fɔ lɔng lɔng tɛm. Ɔda wan dɛn kin day insay 10 ia afta dɛn dɔn no se dɛn gɛt di sik. Aw lɔng yu go ebul fɔ liv dipen pan tin dɛn lɛk:

• Di rεt we yu intellectual abiliti dεm de dכn (cognitive decline) .
• Yu ej we dɛn bin no se yu gɛt dis sik.
• Yu ɔl wɛl bɔdi ɛn ɛni ɔda sik we yu go gɛt.

Alzaima sik wae kin bigin kwik kin go kwik pas de Alzaima sik wae kin gɛt ɔltɛm. Dis min se yu kin gɛt siriɔs sik kwik pas pɔrsin wae gɛt dis sik afta yu dɔn ol 65. Tɔk to yu dɔktɔ bɔt aw fɔ liv wit Alzaima sik wae kin bigin kwik kwik wan (EOAD). I kin ɛp yu fɔ sɛt rial gol dɛn ɛn wetin yu de op fɔ.

Aw yu kin adap fɔ liv wit Alzaima sik wae kin bigin kwik kwik wan?

Fɔ liv wit Alzaima sik wae kin bigin kwik kin rili tranga. Pipul wae kin gɛt Alzaima sik wae kin bigin kwik kwik wan (EOAD) kin stil de woke, ɛn kin gɛt yɔŋ famili wit yɔŋ pikin dɛm . Dis kin kam wit chalenj wae pipul dɛm wae gɛt ɔltɛm Alzaima sik nɔr kin gɛt. Dis kin rili tranga, bɔt mɛmba se nɔto yu wan de pan dis waka.

Yu gɛt rayt fɔ fɛn di savis dɛn we yu nid na yu wokples. Yu dɔktɔ kin tɛl yu bak bɔt ɔda tin dɛn we go ɛp yu. Yu kin bigin fɔ plan fɔ tumara bambay bifo yu sik dɛn go wɔs. Fɔ ɛgzampul, yu kin tink bɔt advans dairektv , ligal ɛn faynɛns plan.

If yu nid sɔpɔt, tɔk to pɔsin we sabi bɔt mental wɛlbɔdi biznɛs . E kin rili kɔmɔn fɔ mek pipul dɛm wae gɛt Alzaima sik wae kin bigin kwik kwik wan ɛn dɛn famili kin fil ɛkstra strɛs, wɔri, ɛn pwɛl hat , mɔr lɛk afta dɛn dɔn no se dɛn gɛt dis sik. Dɛn filin dɛn de na rial tin ɛn i fayn, bɔt dɛn nɔ nid fɔ kɔntrol yu layf. Pɔsin we sabi bɔt mɛntɛl hεlth kin ɛp yu fɔ ɔndastand aw yu de tink ɛn fil ɛn ɛp yu fɔ bia wit dɛn.

Ustɛm a fɔ go to dɔktɔ?

If yu gɛt ɛni prɔblɛm wit yu mɛmori ɔ tink, go to dɔktɔ wantɛm wantɛm .

Yu go nid fɔ de chɛk yu dɔktɔ ɔltɛm. I go wach aw yu sik de go bifo ɛn ajɔst yu tritmɛnt as nid de.

Yu kin aks yu dɔktɔ kwɛstyɔn dɛn bak lɛk dɛn wan ya:

• Us sayn ɔ chenj dɛn mi ɛn mi famili fɔ luk fɔ?
• Wan we de fɔ no aw di sik go go bifo kwik kwik wan?
• Wetin na di bɛst tritmɛnt fɔ mi?
• Yu kin gi advays bɔt ɛni kɔmyuniti risɔs we go ɛp mi famili fɔ ajɔst to dis sityueshɔn?

Ɔlman kin fɔgɛt smɔl smɔl tin dɛn wan wan tɛm, ɔ wantɛm wantɛm dɛn kin fɔgɛt wetin dɛn bin de tɔk we dɛn de tɔk. I nɔto sɔntin fɔ wɔri bɔt. Nɔbɔdi nɔ sabi yu maynd ɛn yu bɔdi pas yu. Bɔt if yu de wɔri se yu mɛmori ɔr tinkin de chenj bad bad wan—especially if e kin apin wantɛm wantɛm—to dɔktɔ.

So, wetin na di impɔtant tin dɛn we wi want fɔ kɛr go na os frɔm dis atikul?

Alzaima sik wae kin bigin kwik na wan siriɔs sik wae kin afɛkt pipul dɛm wae nɔr rich 65 ia .

Pan ɔl we no mɛrɛsin nɔr de fɔ dis sik, if yu no bɔt dis sik kwik kwik wan ɛn trit am, dat kin ɛp fɔ kɔntrol di sayn dɛm ɛn slo fɔ mek di sik go bifo. Mɛmba se nɔto yu wangren de. Dɔktɔ dɛn de, pipul dɛn we sabi bɔt mental wɛlbɔdi biznɛs, ɛn sɔpɔt grup dɛn de we go ɛp yu ɛn yu famili fɔ bia wit dis prɔblɛm.

Tek kia ɔf yu bren wɛlbɔdi. If yu notis ɛni chenj, nɔ ignore dɛn.

` Alzaima, fɔgɛt, mɛmori, bren sik, nyurolɔjik sik, dimɛnshɔn, EOAD