Yu gɛt wan lump na yu bɔdi? Yu tink se dis kin bi Epithelioid Sarcoma? Mek wi no fɔ tru!

Na nɔmal tin fɔ mek yu wɔri smɔl we yu si smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl. Sɔntɛnde lɛk dat, yu kin tink bɔt bɔku tin dɛn. "Wetin na dis? I denja?" Kwɛstyɔn dɛn lɛk dis kin kam na wi maynd. Tide wi go tɔk bɔt wan kayn kansa we nɔ kin bɔku we kin apin lɛk dis kayn lumps . Dɛn kɔl dat Epithelioid Sarcoma . Pan ɔl we di nem kin tan lɛk se i strenj smɔl, i fayn fɔ no bɔt am.

Wetin na Epithelioid Sarkoma? Fɔ bi prɛsis...

Fɔ tɔk am simpul wan, Epithelioid Sarcoma (ES) na wan kayn kansa we nɔ kin bɔku ɛn we de pan wan grup we gɛt kansa we dɛn kɔl sɔft tisu sarkoma . “Sɔft tisu” de tɔk bɔt di tin dɛn we de na wi bɔdi lɛk mɔsul, fat tisu, blɔd vesel, ɛn nɛv. So dis kansa kin kam na dɛn kayn ples dɛn de.

Bɔku tɛm i kin bigin lɛk wan smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl . Bɔt, i kin divɛlɔp ɛnisay na yu bɔdi. Sɔntɛnde, pas wan lump kin kam. Sɔm pipul dɛn kin gɛt ɔlsa bak na dɛn skin usay di lumps de.

Di bɛst pat na dat, epithelioid sarcoma na kansa we de gro sloslo . Jɔs tink bɔt, sɔm pipul dɛn kin gɛt dis kayn kansa fɔ sɔm mɔnt, ivin fɔ lɔng tɛm, ɛn dɛn nɔ kin sho ɛni sayn. Dat min se i kin gro insay yu bɔdi we yu nɔ ivin no.

Dɛn kin kɔl dis bak epithelial sarcoma. tu men tכp dεm de fכ dis: distal εn proksimal. Mek wi luk dat tu.

Ɛni kayn we de fɔ dis? Wetin na dɛn?

Yes, as wi bin se bifo, tu men kayn epithelioid sarcoma de.

• Distal tayp: Dis na di kayn we we dɛn kin yuz mɔ . “Distal” min fa frɔm di sɛntrɔm pat na di bɔdi. Dis min se dis kayn tin kin apin mɔ na say dɛn lɛk yu an, yu fut, di fɔs pat pan yu an, ɛn di ɔda pat we de dɔŋ na yu leg .

• Prɔksimal tayp: Dis na di kayn we we nɔ bɔku . “Proximal” min fɔ de nia di sɛntrɔm pat na di bɔdi. So, dis Proximal Epithelioid Sarcoma (PES) kin divεlכp na ples dεm lεk yu chεst, bεlε, armpit, jεnital (i.e. penis כ vulva), כ ed εn nεk .

כltεm, dis proksimal tכp kin big sכmtεm pas da distal tכp de.Vɛks. Dat min se i kin skata kwik kwik wan ɛn i kin wɔs. Bikɔs ɔf dat, i kin tranga smɔl fɔ trit am.

Aw kɔmɔn tin na di epithelioid sarkoma? Udat go mɔs gɛt am?

Dis na rili kansa we nɔ kin apin so ɔltɛm. Jɔs tink bɔt, i pas 50 kayn sɔft tisu sarkoma. כl dεm tכgeda, dεn de mek lεk 1% pan כl di kεnsar dεm na big pipul dεm. εn afta dat, dis εpitεlioid sarkoma na, bak, wan rili sכm nכmba, bכt 1% pan dεn sכft tisu sarkoma dεm. Dat min se, i rili, rili rare.

Masta sabi bukman dɛn se ivin na kɔntri lɛk Amɛrika, naw nɔto 1,000 pipul dɛn we gɛt dis epithelioid sarcoma. So yu kin imajin aw dis nɔ kin apin so ɔltɛm.

Kin,

• Distal tayp ES – di kayn we we kɔmɔn pas ɔl – de afɛkt titi ɛn yɔŋ pipul dɛn mɔ.
• Prɔksimal tayp ES – di kayn we we nɔ kin bɔku, we kin rili bad smɔl – dɛn kin si am mɔ pan ol pipul dɛn .

Wetin na di sayn dɛm we de sho se yu gɛt dis sik? Aw yu no am?

Insay di fɔs stej dɛm, di epithelioid sarcoma nɔ kin kɔz ɛni simptom. Dis min se yu nɔ go notis ɛnitin we nɔ rayt wit am. Bɔt as di tumbu de gro, yu kin notis sɔm sayn dɛn lɛk:

• Nyu lump ɔ swɛlin de apia. Dis kin bi smɔl ɔ big.
• Ɔlsa de fɔm na di skin usay di lump de, we tan lɛk smɔl kɔt ɔ wund.
• Dɛn kin fil pen . Bɔt dis kin apin nɔmɔ if di tumbu big smɔl ɛn prɛs di mɔsul ɔ nerv dɛn we de rawnd am. Nɔto ɔlman kin gɛt pen.
• I kin tan lɛk se wan lump we dɔn de de fɔ lɔng tɛm de kam big .

Impɔtant: If yu notis nyu lump ɔ swɛlin lɛk dis ɛnisay na yu bɔdi, ɔ if yu fil lɛk se wan we dɔn de de de big, yu go mɔs go to dɔktɔ . I kin bi sɔntin we simpul, bɔt i bɛtɛ fɔ mek dɛn chɛk am.

Wetin mek dis kin apin? Wetin na di rizin dɛn?

Fɔ tɔk tru, dɔktɔ dɛn stil nɔ ebul fɔ tɔk fɔ tru wetin rili de mek pɔsin gɛt epithelioid sarcoma. Bɔt risach dɔn sho se i gɛt fɔ du wit wan abnɔmal tin we de na wan jin we dɛn kɔl SMARCB1 . Dis jin na in de tɛl wi bɔdi fɔ mek prɔtin. dis jin mכtεshכn kin apin we i de liv. Dat min se nɔto sɔntin we dɛn bɔn yu wit, bɔku tɛm.

lεk mכst sכft tisu sarkoma dεm, εpitelכid sarkoma dεm kin divεlכp witout klia kכz . Bɔt dɛn kin no se dɛn gɛt kansa afta dɛn dɔn gɛt kansa bifo.De risk fɔ gɛt dis kin bɔrku smɔl fɔ pipul dɛm wae dɔn gɛt redyushɔn tɛrapi.

Apat frɔm dat, masta sabi bukman dɛn dɔn si se pipul dɛn we gɛt sɔm famili kansa sindrom kin gɛt smɔl risk fɔ gɛt epithelioid sarcoma bak. Sɔm pan dɛn tin ya na:

• Gardner sindrom we gɛt di sik
• Nyurofibromatosis Tayp 1 ɛn Tayp 2
• Retinoblastoma we gɛt di sik
• Li-Fraumeni sindrom we gɛt di sik
• Tuberous sklerɔsis kɔmpleks
• Di sik we dɛn kɔl Werner syndrome
• Di sik we dɛn kɔl Gorlin syndrome

Dis na tin we kɔmplikt smɔl, bɔt i fayn fɔ no. If yu gɛt dis sik, tɔk to yu dɔktɔ fɔ gɛt mɔ advays.

Dis sik kin skata ɔlsay na di bɔdi?

כl di tεm dεm, di εpitelכid sarkoma nכ de spre (mεtastasayz) to כda ples dεm. Dat min se, i de de usay i bigin. כltu, sכmtεm, εspεshali di mכr agresiv tכp dεm lεk di proksimal tכp, i kin spre. If i du dat, i go mɔs bi se i go go na yu limf no dɛm, yu lɔng dɛm, ɛn yu bon dɛm .

Aw yu no dis? (Diagnosis) .

Dɔktɔ go du bɔku tɛst fɔ no if i gɛt epithelioid sarcoma. Di men wan dɛn na:

• Fɔ chɛk yu bɔdi : Di dɔktɔ go chɛk yu, ɛn chɛk tin dɛn lɛk usay di lump de ɛn in saiz.
• Bayopsi: Dis na di tɛst we impɔtant pas ɔl . Dɛn kin tek wan rili smɔl pat pan di lump ɛn chɛk am ɔnda maykroskɔp. Na da tɛm de nɔmɔ wi go no fɔ tru if na kansa, ɛn if na so, us kayn.
• Blɔd tɛst fɔ kansa: Sɔm mak dɛn we de sho kansa kin de na di blɔd.
• MRI skan (Magnetic Resonance Imaging – MRI): dis kin si klia wan usay di tכmכro de, in saiz, εn if i dכn spre to di tisu dεm we de rawnd am.
• CT scan (Computed Tomography – CT scans): Dis kin luk bak pan di tכmכro εn si if di kansa dכn spre to כda say dεm lεk di lכng.
• PET skan (Positron Emission Tomography – PET scans): Dis de ɛp fɔ fɛn eria dɛn na di bɔdi usay di kansa sɛl dɛn de wok.

Sɔntɛm yu nɔ go nid fɔ du ɔl dɛn tɛst ya. Yu dɔktɔ go disayd us tɛst dɛn we yu nid fɔ du bay aw yu sik.

Wetin na di tritmɛnt?

Yu dɔktɔ go pik aw fɔ trit yu bay sɔm tin dɛn, lɛk di sayz we di tumbu gɛt, usay i de, if di kansa dɔn skata to ɔda say dɛn, aw yu bɔdi ebul fɔ wɛl, ɛn wetin yu lɛk.

Ɔpreshɔn

di men εn mכst kכmכn tritmεnt fכ epithelioid sarkoma na fכ pul di tכmכro wit כpεrayshכn . If di kansa dɔn skata to di limf no dɛm we de nia de, di dɔktɔ we de du di ɔpreshɔn kin pul dɛn bak.

Rɛdieshɔn Tɛrapi

Dis na ɔda kɔmɔn tritmɛnt fɔ kansa. I de yuz ɛkstrem rayt we gɛt bɔku ɛnaji fɔ pwɛl di kansa sɛl dɛn. Dɔktɔ dɛn kin gi dis tritmɛnt fɔ mek di tumbu smɔl bifo dɛn du di ɔpreshɔn. Ɔ, dɛn kin yuz am fɔ kil ɛni kansa sɛl we lɛf afta dɛn dɔn du di ɔpreshɔn.

Kimotɛrapi

If di kansa dɔn skata to ɔda pat dɛn na yu bɔdi, yu dɔktɔ kin tɛl yu fɔ tek kemotɛrapi . Dis min se dɛn fɔ gi yu spɛshal mɛrɛsin fɔ kil di kansa sɛl dɛn. Bɔku tɛm, dɛn kin gi dɛn mɛrɛsin ya insay dɛn bɛlɛ. Bɔt dɛn kin gi dɛn bak as pils, wata, krim we dɛn put pan di skin, ɔ injɛkshɔn.

Targeted Drug Tɛrapi

Dis na nyu tritmɛnt. I min fɔ gi mɛrɛsin dɛn we de tɔch di jin ɛn prɔtin dɛn nɔmɔ we de kɔntrol aw di kansa sɛl dɛn de gro ɛn sheb. Dis min se di sɛl dɛn we gɛt wɛlbɔdi nɔ kin gɛt bɛtɛ prɔblɛm. Bɔku kayn mɛrɛsin dɛn de we dɛn kin yuz fɔ dis. Yu dɔktɔ go mek wan patikyula tritmɛnt plan fɔ yu bay aw yu sik. Tazemetostat na wan kayn mɛrɛsin we dɛn kin yuz fɔ epithelioid sarkoma. I de ɛp fɔ trit di kansa sɛl dɛn we dɛn nɔ go ebul fɔ pul ɔltogɛda we dɛn du ɔpreshɔn pan am.

Yu tink se dɛn go ebul fɔ mek dis nɔ apin?

Di tin we sɔri na dat, bikɔs di epithelioid sarcoma kin kam fɔ no rizin, wi nɔ gɛt ɛni we fɔ mek i nɔ kam . Dat min se i at fɔ se, "If yu du dis, i nɔ go apin."

Wetin kin apin if yu gɛt epithelioid sarkoma? Yu tink se dɛn kin mɛn am?

Na nɔmal tin fɔ mek yu fil fred we yu yɛri dis. Bɔt, epithelioid sarcoma na sik we dɛn kin trit , mɔ if dɛn kech am kwik . Yu dɔktɔ go du sɔm tɛst fɔ si aw di tumbu big ɛn if i dɔn skata to ɔda say dɛn. Dɔn, dɛn go mek wan tritmɛnt plan we go fayn fɔ yu.

Sɔntɛm wan tim fɔ dɔktɔ dɛn de we de trit yu. Sɔm pan dɛn tin ya na:

• Yu praymari kia dɔktɔ ( di dɔktɔ we kin si yu).
• Ɔnkɔlɔjis: Dɛn wan ya na ɔtpidik ɔnkɔlɔjis, ɔnkɔlɔji ɔpreshɔn, ɛn dɔktɔ dɛn we de gi kemotɛrapi ɛn redyushɔn tɛrapi.
• Dermatologists: Fɔ prɔblɛm dɛn we gɛt fɔ du wit di skin.
• Pathologists: Dɛn wan wae de luk yu blɔd ɛn bayɔpsi tɛst ripɔt ɛn gi yu di ditel dɛm.
• Tɛrapist dɛm: Pipul dɛm wae de ɛp yu fɔ dil wit de strɛs ɛn frayd wae kin kam wit sik lɛk dis.

di onli we fכ kכl di epithelioid sarkoma kכmplit wan na fכ pul di tכmכro kכmplit wan wit כpεrayshכn . Bɔt nɔto ɔltɛm i nɔ go pɔsibul fɔ pul am kɔmɔt kpatakpata.

If dɔktɔ we de du ɔpreshɔn nɔ ebul fɔ pul di tumbu kpatakpata, bɔku tɛm yu dɔktɔ go tɛl yu fɔ yuz ɔda tritmɛnt dɛn fɔ kɔntrol yu sik. Bikɔs epithelioid sarcoma na kansa we de gro sloslo, bɔku pipul dɛn we gɛt dis sik kin stil liv lɔng ɛn gladi layf .

Bɔrku risach ripɔt de bɔt aw dis sik kin liv. Bɔt bikɔs na sik we nɔ kin bɔku, di statystik dɛn kin difrɛn bad bad wan. Akɔdin to sɔm ripɔt dɛm, di fayv ia sɔvayv rɛt de frɔm 25% to 92%. E kin dipen pan bɔrku tin, lɛk aw de sik de ɛn aw pɔrsin kin du tritmɛnt.

Ustɛm a fɔ go to dɔktɔ?

If yu notis wan ɔnusual lump ɔ swelling ɛnisay na yu bɔdi, nɔ ignore am. Mek shɔ se yu go to dɔktɔ. Pipul wae gɛt epithelioid sarcoma kin gɛt lumps na dɛn fɔs an, an, finga, ɔnda leg, ɔr fut. Bɔt mɛmba se dɛn tumbu ya kin kam ɛnisay na di bɔdi.

Us kwɛstyɔn dɛn yu fɔ aks di dɔktɔ?

If yu ɔ pɔsin we yu lɛk gɛt epithelioid sarcoma, na sɔm kwɛstyɔn dɛn ya yu kin aks yu dɔktɔ:

• Usay di tumbu de?
• Na wan tumbu nɔmɔ a gɛt? Ɔ ɔda wan dɛn de?
• Yu tink se di kansa dɔn skata to ɔda pat dɛn na di bɔdi?
• Us tritmɛnt yu kin advays?
• Aw lɔng mi tritmɛnt go tek?
• Aw a go fil we dɛn de trit mi? (Tin dɛn lɛk sayd ɛfɛkt)
• Ɛni ples de we a go lan mɔ bɔt dis? (lɛk wɛbsayt dɛn we pɔsin kin abop pan, buk dɛn)

Na nɔmal tin fɔ mek yu fil fred, vɛks, ɛn fil bad we yu gɛt diagnosis lɛk dis. Tɔk to yu dɔktɔ bɔt wetin fɔ ɛkspɛkt bifo, di tɛm we yu de trit yu, ɛn afta yu dɔn trit yu. I kin fayn bak fɔ tɔk to pɔsin we de gi advays ɔ we de mɛn pipul dɛn. Dɛn kin ɛp yu fɔ dil wit de kɔmpleks filin wae yu de gɛt na dis kayn tɛm. If i pɔsibul, jɔyn sɔpɔt grup wit pipul dɛn we de go tru di sem tin lɛk yu. Dis kin ɛp yu fɔ lɛ yu nɔ fil se yu wangren de.

Mɛsej we dɛn kin kɛr go na os

• Epithelioid sarcoma na wan kansa we nɔ kin apin so ɔltɛm, we kin ambɔg sɔft tisu .
• Bɔku tɛm, i kin gɛt lumps na di limb dɛnI kin tan lɛk rash, sɔm tɛm dɛn kin gɛt lɛsin dɛn na di skin.
• Sɔntɛm di sayn dɛm nɔr kin apia na di fɔs stej dɛm.
• I gɛt fɔ du wit wan prɔblɛm we de na wan jin we dɛn kɔl SMARCB1 , bɔt dɛn nɔ no yet di rayt tin we mek i apin.
• Ɔpreshɔn na di men tritmɛnt . Dɛn kin yuz redyushɔn tɛrapi, kemotɛrapi, ɛn mɛrɛsin dɛn we dɛn kin yuz fɔ mɛn pipul dɛn bak.
• I at fɔ mek dɛn nɔ gɛt am , bɔt if dɛn no am kwik, dɛn kin trit am .
• If yu notis nyu lump na yu bɔdi, go to dɔktɔ wantɛm wantɛm.
• Nɔ fred, nɔ panik, ɛn fala di rayt advays we di dɔktɔ gi yu . Nɔto yu wan, dɔktɔ ɛn pipul dɛn we yu lɛk de fɔ ɛp yu.

Mɛmba se dis atikul na fɔ jɔs tɔk bɔt ɔltin. If yu gɛt ɛnitin we de mɔna yu, i go fayn fɔ go to dɔktɔ.