Yu gɛt wan strenj lump na yu bɔdi? I kin bi wan (Hamartoma)! Lɛ wi tɔk bɔt dis.

Yu dɔn ɛva fil smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl. Ɔ yu dɔn ɛva wɔnda wetin i bi we dɔktɔ kɔl yu ``Hamartoma''? Wetin na dis ``Hamartoma''? Lɛ wi tɔk bɔt am simpul wan, di we we yu go ɔndastand.

Wetin na `(Hamartoma)`? Lɛ wi ɔndastand am simpul wan!

Okay, naw mek wi si wetin dis `(Hamartoma)` bi. Fɔ tɔk am simpul wan, na smɔl tumbu we nɔ gɛt wan prɔblɛm. I de mek frɔm di sem kayn sɛl dɛn we nɔmal fɔ de na wi bɔdi. Bɔt smɔl difrɛns de. dat min se dεn sεl dεm ya kin kam togεda sכmtεm we nכ de rεgulεr, we nכ כganayz fכ fכm dis tכmכro. I tan lɛk fɔ put sɔm pan di sem kayn tɔys dɛn na wan pail instead fɔ put dɛn ɔdasay. Di wɔd `(Hamartoma)` kɔmɔt frɔm tu Grik wɔd dɛn. ``Hamartia`` min ``fɔlt`` ɔ ``dɛfisiɛns``. ``Oma`` min ``tumor``. So, dis min se na tכmכro we de divεlכp bikoz fכ sכm kayn dεfekt.

Di tin we impɔtant pas ɔl na dat dɛn ``Hamartomas`` ya nɔto kansa . Dɛn nɔ kin skata ɔlsay na di bɔdi lɛk kansa sɛl dɛn . So natin nɔ de fɔ wɔri bɔt. Bɔt, i kin dipen pan usay dɛn de, sɔntɛnde dɛn kin mek dɛn gɛt smɔl smɔl prɔblɛm dɛn.

usai na di bכdi dis `(Hamartoma)` kin divεlכp?

dis ``Hamartomas`` kin rili fכm enisay na wi bכdi. Bɔt sɔm ples dɛn de we pipul dɛn kin si dɛn mɔ.

• di lכng dεm : bכku tεm, dεn ``Hamartomas`` dεm ya de divεlכp na di lכng dεm. כnli 10% pan di benign tכmכro dεm we dεn fכnshכn na di lכng dεm dεn se na dis kayn. sכmtεm, dεn kin fכnshכn dεm insidεnt wan we dεn tek chεst `` X-ray`` fכ sכm כda rizin.
• Skin: Dɛn kin si hamartomas mɔ na di ed ɛn nɛk, mɔ na di fes, di lip, ɛn biɛn ɛn dɔŋ di yes. Sɔntɛnde, dɛn kin tan lɛk bɔn mak.
• At : Dɛn tin ya kin kam bak na di at. Cardiac rhabdomyoma na wan kayn hamartoma we nɔ kin bɔku we kin apin na di at. Bɔku tɛm dɛn kin si dɛn tin ya na di mama in bɛlɛ (we i gɛt bɛlɛ ) ɔ we i smɔl. Pan ɔl we i nɔ kin apin so ɔltɛm, na dɛn tumbu ya kin kam pan yɔŋ pikin dɛn at.
• Bren:wan kayn tכmכro we dεn kכl haypothalamic hamartoma de divεlכp na di haypothalamus, we na wan pat pan di bren we de εp fכ rεgεl bכku imכtant prכsεs dεm na di bכdi. Dɛn tumbu ya kin de we dɛn bɔn am, bɔt bɔku tɛm dɛn kin jɔs sho di sayn dɛn we dɛn smɔl ɔ we dɛn yɔŋ. Dɛn kin mek yu gɛt sɔm kayn sik lɛk wae yu nɔr de fil fayn , yu nɔr de si fayn , ɛn yu nɔr kin ebul fɔ mared kwik kwik wan .
• brεst: lεk 5% pan di bεnign lumps dεm na uman in brεst kin bi hamartomas. Dɛn kin bɔrku pan uman dɛm wae dɔn pas 35 ia.

pan tap dat, hamartomas kin divεlכp bak na ples dεm lεk di kidni, splin, tayroyd gland, εn bon dεm, we i gεt fכ sכm jεnεtik kכndyushכn dεm lεk PTEN hamartoma tumor syndrome (PHTS).

Dis `(Hamartoma)` de skata ɔlsay na di bɔdi?

Dis na big prɔblɛm fɔ bɔku pipul dɛn. Nɔ, ``Hamartoma`` nɔ de skata ɔlsay na di bɔdi lɛk kansa. Dat min se, i de de usay dɛn mek am. Bɔt sɔntɛnde if dis tumbu gro smɔl, i kin push pan wɛlbɔdi tisu ɔ ɔgan dɛn we de nia de ɛn mek sɔm damej. Bɔt dat nɔ kin apin so ɔltɛm.

Ɔda kɔndishɔn dɛn de we gɛt fɔ du wit `(Hamartoma)`?

Yes, Hamartoma kin gɛt fɔ du wit sɔm kayn jenɛtik kɔndishɔn dɛn we nɔ kin apin so ɔltɛm. insay dεn kכndyushכn dεm ya, Hamartoma de kכz bay wan mכtεshכn na wan jin.

• (Pallister-Hall syndrome - PHS): Dis kכndyushכn de sho se di mכtεshכn dεm na di jin `GLI3`. כlmost 5% pan di pipul dεm we gεt `(Hypothalamic hamartomas)` na di bren kin gεt dis `PHS` kכndishכn bak.
• Tuberous sclerosis: Dis kכndyushכn kin mek ``Hamartoma'' fכm na difrεn כgan dεm lεk di bren, at, kidni, skin, εn yay.
• ( Nyurofibromatosis Tayp 1 - NF1): Dis na bak wan jεnεtik kכndyushכn we nכ kin apin. insay dis, ``Hamartoma`` kin divεlכp insay di nεv dεm כlsay na di bכdi.
• (PTEN hamartoma tumor syndrome - PHTS): Dis na grup fכ sik dεm we de sho se di mכtεshכn dεm na di `PTEN` jin. `(Cowden syndrome)` ɛn `(Bannayan-Riley-Ruvalcaba sindrom - BRRS)` na sɔbtayp dɛm fɔ dis. `(Hamartoma)` kin divεlכp na ples dεm lεk di brεst, di uterus, di tayroyd gland, di gεstrointestinal sistεm (`GI tract`), εn di skin.
• Peutz-Jeghers syndrome (PJS): Dis kin gɛt fɔ du wit wan muteshon na di jin STK11/LKB1. Pipul dεm wae gεt PJS kin gεt hεmartomas na dεn lכng, bεlε, blad, sכm intestinal, kכlon, εn rεktum.

If yu gɛt jenɛtik kɔndishɔn lɛk dis, yu dɔktɔ kin tɛl yu fɔ tɛst yu jɛnɛtiks ɔ advays.

Wetin na di simptom dɛm fɔ `(Hamartoma)`?

Bɔrku tɛm, dɛn `(Hamartomas)` ya nɔ kin sho ɛni simptom (`asymptomatic`). Dat min se yu kin gɛt dɛn na yu bɔdi we yu nɔ go fil bad. Bɔt sɔm tɛm, di sayn dɛn kin apin nɔmɔ we dis tɔŋ gro smɔl ɛn prɛs di tisu dɛn we de dɔŋ. If dat apin, di sayn dɛm de dipen pan usay di `(Hamartoma)` de. fכ egzampl, if wan `(Hamartoma)` na di lכng dεm big, yu kin gεt tin dεm lεk fכ kכf εn i kin at fכ brith. If wan de na di bren, lɛk aw wi bin dɔn tɔk, i kin mek i gɛt sik ɛn i kin gɛt prɔblɛm wit di we aw i de si.

Wetin na di tin dɛn we kin mek pɔsin gɛt Hamartoma?

Sayɛnsman dɛn stil nɔ no di rayt tin we mek Hamartoma. Bɔt lɛk aw wi bin dɔn tɔk, i gɛt sɔntin fɔ du wit sɔm tin dɛn we kin apin to pɔsin in jɛnɛtiks. Bɔku tɛm, dɛn kin gɛt dɛn jenɛtik kɔndishɔn ya. Dat min se, dɛn kin kam bikɔs ɔf wan jenɛtik chenj we dɛn gɛt frɔm wan pan di mama ɛn papa dɛn.

Yu tink se Hamartoma kin mek prɔblɛm dɛn?

Bɔku pan di hamartoma dɛn nɔ kin siriɔs. Bɔt dɛn kin mek prɔblɛm if dɛn gro big ɛn pwɛl wan ɔgan ɔ bɔdi strɔkchɔ. Fɔ ɛgzampul, wan kadyak rabdomyoma na di at kin mek di at nɔ wok fayn if i ambɔg di at wok. semweso, wan haypothalamic hamartoma na di bren kin mek di hכmon imbalans εn di kכgnitiv impεryans if i intafεr di fכnshכn fכ di haypothalamus. Bɔt nɔ wɔri, yu dɔktɔ kin wach di hamartoma ɛn pul am if nid de.

Aw dɛn kin no bɔt `(Hamartoma)`?

Bɔku tɛm, hamartomas nɔ kin mek pɔsin gɛt ɛni sayn, so dɛn kin no am bay we dɛn de skan fɔ ɔda sik. Sɔntɛnde, i kin tranga fɔ no if hamartoma na tumor ɔ nɔto tumor, mɔ dipen usay i de. Yu dɔktɔ go chɛk yu ɛn aks yu bɔt yu mɛdikal istri. Bɔku tɛm, dɛn go nid fɔ du ɔda tɛst fɔ no se na hamartoma.

Wetin na di tɛst dɛn we dɛn kin du fɔ no if pɔsin gɛt sik?

• X-ray: Na low-dose radiation test we de tek pikchɔ fɔ bon ɛn sɔft tisu. di hamartomas na di lכng dεm sכmtεm de luk lεk "pכpכn" pan εks-ray. Dis kin ɛp fɔ no difrɛns frɔm di tumbu dɛn we gɛt kansa.
• Ultrasound: I de yuz sawnd wev fɔ tek pikchɔ fɔ di sɔft tisu dɛn we de insay di bɔdi.
• CT scan (Computed tomography): Na skan we de yuz bɔku ɛkstrem rayt fɔ tek krɔs-sekshɔn pikchɔ dɛn fɔ di sɔft tisu ɛn bon dɛn we de insay di bɔdi. CT skan kin rili yus fכ fכn di lכng hamartomas.
• MRI (Magnetik rɛsɔnans imej): .Dɛn kin yuz big magnet ɛn redio wev fɔ tek ditayli pikchɔ dɛn bɔt di sɔft tisu dɛn we de insay di bɔdi.
• Mammogram: Na lכw dכz tεst we de egzamin di brεst tisu. כl di brεst hamartomas dεn kin fכnshכn we dεn de du mammogram, we dεn kin yuz fכ sכk fכ kεnsar.
• Bayopsi: Insay dis, dɔktɔ kin tek wan smɔl pat pan di tumbu ɛn sɛn am na lɛbɔtri. na de, wan ``Pathologist`` de luk di sεl dεm כnda maykroskכp. dis ``Biopsy`` na di onli we fכ no fכ sכri if na benign tumor, lεk ``Hamarthoma``, כ kansa tumor. Dis na di mɔs difinitiv we fɔ no di sik.

Aw dɛn kin trit Hamartoma?

Di tritmɛnt dipen pan tin dɛm lɛk usay di hamartoma de ɛn if yu de gɛt sɔm sayn dɛm frɔm am.

• If no prɔblɛm nɔ de: If di tumbu nɔ de kɔz ɛni prɔblɛm ɔ de mek pɔsin gɛt di sik, di dɔktɔ kin disayd fɔ wach am we i nɔ gɛt tritmɛnt. Dis min se dɛn go skan am wan wan tɛm fɔ si if i de big ɔ i de chenj.
• If sɔm sayn dɛn de ɔ if dɛn tink se pɔsin gɛt kansa: If na so i bi, bɔku tɛm na ɔpreshɔn fɔ pul di tumbu na di men tritmɛnt.

Wetin na di patikyula ɔpreshɔn dɛn we dɛn kin du fɔ pul wan hamartoma?

dis kin difrεn bak dipכnt pan usay di hamartoma de. Fɔ di lɔng hamartoma:

• wed rεsεkshכn: insay dis, dεn kin kכt wan sכm sכm pat we shep lεk wed na di lכng usay di tכmכro de kכmכt εn pul am. Along wit di tumor, dεn kin pul sכm hεlty tisu dεm we de rawnd am bak.
• Lobectomy: Dɛn kin pul wan lobe na di lכng kpatakpata, if di hamartoma de na da lobe de. Wi rayt lכng gεt tri lob dεm εn wi lεft lכng gεt tu lob dεm.
• Nyumɔnektomi: Dɛn kin pul di wan ol lɔng. Bɔt i nɔ kin izi fɔ mek dɛn nid fɔ du dis kayn big ɔpreshɔn pan hamartoma.

Fɔ `(Hypothalamic hamartomas)` na di bren:

• Risekshɔn ɔpreshɔn: Wan dɔktɔ we de du ɔpreshɔn kin kɔt di tumbu ɛn pul am.
• Ablashɔn: Dɛn kin pwɛl di tumbu bay we dɛn yuz ay ɔt ɔ lɛsa raytin.
• (GammaKnife® redio ɔpreshɔn): Dis nɔto tradishɔnal ɔpreshɔn. Raydyushɔn de pwɛl di tumbu bay we i de dayrɛkt wan pawaful bim we gɛt ɛnaji pan am. I de pul di tisu we de ambɔg pɔsin wit prɛsishɔn, jɔs lɛk ɔpreshɔn.

Wetin kin apin if a gɛt `(Hamartoma)`?

Bɔrku pan di hamartomas nɔr siriɔs, so nɔr de ala. If hamartoma de afɛkt wan ɔgan ɔ i big fɔ mek i pwɛl, bɔku tɛm ɔpreshɔn kin sɔlv di prɔblɛm. Sɔntɛnde, i kin at fɔ pul wan hamartoma. fכ egzampl, sכm haypothalamic hamartomas de divεlכp nia di optik nεv, we kin pwεl we dεn du כpεrayshכn.

So, i rili impɔtant fɔ tɔk to yu dɔktɔ gud gud wan ɛn no if yu nid fɔ pul yu hamartoma, ɛn if na so, us kɔmplikɛshɔn ɔ risk i kin kam wit.

Yu tink se ``Hamartoma'' kin bi kansa?

Dis na ɔda fred we bɔku pipul dɛn kin fred. Di chans fɔ mek hamartoma tɔn to kansa rili smɔl. Dat min se, i nɔ kin apin so ɔltɛm. Bɔt na di tin ya. Sɔm jɛnɛtik kɔndishɔn dɛn we gɛt fɔ du wit hamartoma (fɔ ɛgzampul, Cowden syndrome, we na wan sɔbtayp fɔ PHTS) kin mek di risk fɔ gɛt kansa bɔku. If na so i bi, nɔto di hamartoma de mek di risk fɔ gɛt kansa bɔku, bɔt na di jenɛtik kɔndishɔn. So, if yu gɛt dis kayn jenɛtik kɔndishɔn, i impɔtant fɔ de chɛk yu ɔltɛm fɔ si if yu gɛt kansa.

Wetin a fɔ aks mi dɔktɔ?

Wae yu dɔn no se yu gɛt ``Hamartoma'', sɔm tin dɛn de we yu fɔ aks yu dɔktɔ bɔt am. Nɔ fred fɔ aks dɛn kwɛstyɔn ya:

• Wetin mek a divɛlɔp dis `(Hamartoma)`?
• A nid fɔ pul dis `(Hamartoma)`?
• Wetin na di sayn dɛm wae de sho se dis nid tritmɛnt?
• Dis ``Hamartoma`` kin bi wan sayn fɔ ɔda siriɔs kɔndishɔn?
• Yu tink se fɔ advays ɔ tɛst di jɛnɛtiks go bɛnifit mi ɔ ɛnibɔdi na mi famili?

Fɔ dɔn, tin dɛn fɔ mɛmba (Take-Home Message) .

Okay, so frɔm wetin wi dɔn tɔk bɔt, a tink se yu dɔn gɛt gud aidia bɔt `(Hamartoma)`. Di impɔtant tin na dat, `(Hamartoma)` nɔ denja bɔku tɛm. Dɛn nɔr kin gɛt kansa, ɛn dɛn nɔ kin skata ɔlsay na di bɔdi. Bɔrku tɛm, dɛn nɔr nid fɔ gɛt tritmɛnt. Bɔt if sɔm sayn dɛn de, ɔ if di dɔktɔ gɛt ɛni dawt, dɛn kin du ɔpreshɔn fɔ pul dɛn ɛn sɔlv di prɔblɛm.

If dɔktɔ tɛl yu se yu gɛt ``Hamartoma'', nɔ fred am we yu nɔ nid, tɔk to yu dɔktɔ fayn fayn wan ɛn disayd wetin na di bɛst nɛks tin fɔ yu. Fɔ kia fɔ yu wɛlbɔdi na di tin we impɔtant pas ɔl!

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