Wi bɔdi in smɔl hiro: Ɔltin bɔt Erythropoietin!

Yu dɔn ɛva yɛri bɔt sɔntin we dɛn kɔl ‘Erythropoietin’ ɔ ‘EPO’? Sɔntɛm yu dɔktɔ dɔn tɔk bɔt am, ɔ if yu gɛt wan sik lɛk anemia, yu kin no di nem smɔl. Dis na rili wɔndaful ɛn rili impɔtant ɔmon na wi bɔdi. Tide, wi go tɔk bɔt am simpul wan we yu go ɔndastand.

Wetin na Ɛritropoɛtin?

Fɔ tɔk am simpul wan, Erythropoietin na ɔmon we yu kidni dɛn kin mek mɔ. Wi kin kɔl am bak EPO fɔ shɔt. di men wok we dis EPO de du na fכ εp fכ mek di rεd bכdi sεl dεm, dat na, rεd blכd sεl dεm (εrythrocytes) . Dis EPO de wok lɛk se manija de tɛl wi bɔdi in rɛd blɔd sɛl faktri fɔ ‘mek mɔ!’.

Sɔntɛnde, dɔktɔ dɛn kin yuz wan we we dɛn mek wit ɛrythropoietin, mɔ fɔ trit di wan dɛn we nɔ gɛt bɛtɛ blɔd we kin kam wit krɛse sik (CKD) . Imajin, bikɔs sɔm pipul dɛn kidni nɔ de wok fayn, dɛn nɔ de mek dis EPO ɔmon inof. Dɔn dɛn kin gɛt anemia. Na da tɛm de dis sintetik EPO de ɛp.

Bɔt sɔm atlet dɛn kin yuz am di rɔŋ we fɔ mek dɛn ebul fɔ du mɔ. di rizin na dat EPO de mek di כksijεn we de rich na dεn mכsul dεm bכku. Dat nɔto gud tin atɔl, bikɔs i kin mek wi gɛt siriɔs wɛlbɔdi prɔblɛm.

Dɛn kin kɔl ɛrythropoietin bak wit ɔda nem dɛn lɛk ɛrythropoietin, hematopoietin, ɛn hemopoietin. Bɔt di nem dɛn we dɛn kin yuz mɔ na Erythropoietin ɛn EPO.

Wetin erythropoietin (EPO) de du to wi bɔdi?

Dis na kwɛstyɔn we rili impɔtant. EPO na wan big ɔmon we de ɛp wi bɔdi fɔ mek rɛd blɔd sɛl dɛn . Naw, wetin mek wi nid rɛd blɔd sɛl? We yu de blo, udat de kɛr di ɔksijɛn we de kam insay yu lɔng to ɔl di pat dɛn na yu bɔdi, to ɛvri sɛl? Na dat di rɛd blɔd sɛl dɛn kin du. Tink bɔt am lɛk smɔl trak dɛn we de kɛr ɔksijɛn ɔlsay na yu bɔdi. EPO de tɛl dɛn trak ya fɔ mek dɛn.

We ɔksijɛn rich na wi sɛl dɛn, i kin tɔn to ɛnaji. Dis ɛnaji impɔtant fɔ ɔl wi wok. Dɔn, dɛn rɛd blɔd sɛl ya kin kɛr di kabon dayɔgzayd we kin kɔmɔt na wi sɛl dɛn bak na di lɔng. Frɔm de, wi kin pul am.

Wetin kin apin na dis: Spɛshal sɛl dɛn na yu kidni kin no se di ɔksijɛn lɛvɛl na yu blɔd nɔ bɔku. We dɛn no dat, dɛn kin mek dɛn prodakshɔn fɔ EPO bɔku. Dɔn dis EPO kin go na di pat we tan lɛk spɔnj na wi bon dɛn, we na di bon mɛro , ɛn se, ‘Okay, naw mek mɔ rɛd blɔd sɛl dɛn!’

Bɔt if di sɛl dɛn na di kidni dɛn no se ɔksijɛn de na di blɔd, dɛn kin mek di EPO nɔ bɔku. Dis tan lɛk sapɔt-to-dimand sistɛm. Dɛn kin prodyuz mɔ we di bɔdi nid am, ɛn dɛn kin prodyuz smɔl we di nid nɔ bɔku.

Yu nɔ tink se i wɔndaful aw tin dɛn lɛk dis kin apin na wi bɔdi? Dɛn dɔn plan ɔltin so!

Sɔm mɛrɛsin kin afɛkt di kayn EPO we di kidni dɛn kin mek. Dis kin mek dɛn prodyuz tumɔs EPO, ɔ nɔ kin du am. Dɛn tu tin ya kin mek di rɛd blɔd sɛl nɔ balans.

Wetin kin apin if di erythropoietin (EPO) lɛvɛl go ɔp?

If di EPO lɛvɛl go ɔp we i nɔ nid, dat min se if di bɔdi inkrisayz EPO we i nɔ rili nid am, di nɔmba fɔ di rɛd blɔd sɛl dɛn bak go go ɔp. Wi kɔl dis polycythemia . Fɔ tɔk am simpul wan, tumɔs rɛd blɔd sɛl dɛn de na di blɔd. Dis na prɔblɛm bak, bikɔs di blɔd kin tik ɛn blɔd kin klɔt.

Wetin mek di lɛvɛl we di erythropoietin (EPO) de go ɔp?

Bɔku rizin dɛn de we mek di EPO lɛvɛl kin ay pasmak:

• Fɔ liv na say we ɔksijɛn nɔ bɔku fɔ lɔng tɛm: Imajin se if pɔsin kɔntinyu fɔ smok, di ɔksijɛn we de rich na in bɔdi nɔ go bɔku. Dɔn di kidni dɛn kin tink se, ‘O, ɔksijɛn nɔ de, wi nid fɔ mek mɔ rɛd sɛl dɛn,’ ɛn dɛn kin mek mɔ EPO. Semweso, if pɔsin de liv na say we rili ay lɛk Nuwara Eliya fɔ lɔng tɛm, di EPO lɛvɛl kin go ɔp bak bikɔs di ɔksijɛn lɛvɛl we de na di ays de smɔl. Bɔt i nɔmal fɔ mek EPO go ɔp na dis ayt, na adapteshɔn fɔ di bɔdi.
• Anemia nɔr kin kam bikɔs ɔf kidni sik: Sɔntɛnde, anemia nɔr kin kam bikɔs ɔf wan kidni prɔblɛm. Bɔt bikɔs di rɛd blɔd sɛl dɛn nɔ bɔku ɔ di rɛd blɔd sɛl dɛn nɔ de wok fayn, di kidni dɛn kin no se dɛn nɔ de gɛt bɛtɛ ɔksijɛn. Ivin da tɛm de, dɛn kin mek mɔ EPO fɔ ɛp fɔ mek rɛd blɔd sɛl dɛn. Dis na rili nɔmal tin we di bɔdi kin du.
• Sɔm kayn tumbu dɛn: Pan ɔl we dɛn nɔ kin bɔku, sɔm kayn tumbu dɛn kin mek di kidni dɛn pul bɔku bɔku EPO.

Wetin kin apin if di εrythropoietin (EPO) lεvεl dεm dכn dכn?

Di men tin we kin mek di EPO nɔ bɔku na di sik we dɛn kɔl kronik kidni (CKD) . As wi bin dɔn tɔk, we di kidni dɛn pwɛl, dɛn nɔ kin ebul fɔ mek EPO fayn fayn wan. Dis kin mek di EPO lɛvɛl smɔl. Dis kכndyushכn, CKD, εn lכw EPO lεvεl kin mek yu gεt anemia. Dis min se yu kin fil taya, yu kin fil pen, ɛn yu kin gɛt prɔblɛm fɔ blo.

Wetin mek di lɛvɛl we di erythropoietin (EPO) de go dɔŋ?

Pan ɔl we di men tin we kin mek pɔsin gɛt sik na CKD, ɔda tin de we kin mek i sik. Dat na wan sik we dɛn kɔl Polycythemia Vera . Dis na wan kayn kansa we kin apin na di blɔd. Bikɔs ɔf wan jenɛtik muteshɔn, di bon mɛro de mek tumɔs rɛd blɔd sɛl dɛn. Dɔn di kidni dɛn kin fil se, ‘O, tumɔs rɛd blɔd sɛl dɛn de na di blɔd, wi nɔ nid fɔ mek EPO igen.’ So dɛn kin ridyus di prodakshɔn fɔ EPO. Dis na tin bak we kin mek EPO nɔ bɔku.

Us tritmɛnt dɛn kin du if di EPO lɛvɛl smɔl?

If di EPO lɛvɛl smɔl, dɛn kin trit am bay we dɛn de trit di ɔndalayn kɔz . Dat min se if na kidni sik, dɛn kin trit am, if na ɔda tin we kin mek i sik, dɛn kin trit am.

Bɔt di men tritmɛnt fɔ anemia we di EPO lɛvɛl smɔl na we dɛn kɔl rikombinɛnt ɛrithropoietin . Dɛn kin kɔl dɛn tin ya bak ɛrythropoietin-stimulating agents (ESA) . dis na sεntetik vεshכn dεm fכ di EPO כmon we dεn mek na lab. Dɔktɔ dɛn kin klon di EPO jin ɛn gi yu as injɛkshɔn. Dɔn i kin go insay yu bɔdi ɛn mek yu bon mɛro bigin fɔ mek mɔ rɛd blɔd sɛl dɛn.

Dɛn kin gi dis tritmɛnt mɔ fɔ trit anemia we kin kam bikɔs di kidni nɔ kin wok fayn. Dɛn kin gi am bak to pipul dɛm wae gɛt sɔm kayn kansa wae nɔr kin bɔrku.

Bɔt dɛn ESA ya kin mek sɔm sayd ɛfɛkt dɛn:

• Di ay blɔd prɛshɔn
• Fiva
• Diziz we pɔsin kin gɛt
• Vɔmit
• Pen na di say we dɛn injɛkshɔn

So, i rili impɔtant fɔ tek dis tritmɛnt insay di rayt doz, lɛk aw dɔktɔ advays yu.

Aw dɛn kin mɛzhɔ di lɛvɛl we di erythropoietin (EPO) de?

Yu dɔktɔ kin mɛzhɔ yu EPO lɛvɛl wit wan simpul blɔd tɛst. Dis blɔd tɛst kin no di chenj dɛn we de apin na yu blɔd sɛl dɛn we de afɛkt di rilis fɔ EPO. Dis kin ɛp fɔ no if yu gɛt polycythemia, anemia, ɔ ɔda kayn bon mɛrɔ.

Di dɔktɔ ɔ nɔs go pik wan vein na yu an ɛn klin di skin de wit sɔntin lɛk ayodin ɔ isopropyl alcohol. afta dat, wan nidul we rili tin (wan 21 gej nidul - we sכm sכm sכm pas di tip fכ wan iaring) go tek sכm sכm blכd frכm yu vein. Dɛn go sɛn di blɔd sɛmpul to wan lab fɔ mek dɛn analays am.

Wae di lab rizulyt dɔn kam, yu dɔktɔ go tɔk to yu bɔt dɛm ɛn ansa ɛni kwɛstyɔn wae yu gɛt. Mɛmba se, ivin if yu EPO lɛvɛl de insay di nɔmal rɛnj, yu kin stil nid ɔda tritmɛnt. Dat go bi to yu dɔktɔ fɔ disayd.

Wetin na di nכmal εrythropoietin (EPO) lεvεl?

Dɔktɔ dɛn kin mɛzhɔ EPO insay miliyunit pan wan mililita (mU/mL) . di EPO lεvεl fכ hεlty pכsin kin kכmכt frכm 4 to 26 mU/mL.

Bɔt dɛn valyu ya na yu yon:

• Ej
• Bɔy ɔ gal
• Ɔl di wɛlbɔdi stetmɛnt

I kin difrɛn difrɛn tin dɛn, lɛk: So, na yu dɔktɔ nɔmɔ go ebul fɔ ɛksplen yu rizɔlt kɔrɛkt wan ɛn tɛl yu if dɛn de insay wɛlbɔdi rɛnj ɔ ausayd am. So, nɔ mek yu yon diagnosis bay wetin de na di intanɛt.

I posibul fכ inkrεs di εrythropoietin (EPO) lεvεl na nכmal wan?

If yu gɛt kronik kidni sik (CKD) ɔ anemia wit lɔw EPO lɛvɛl, sɔm chenj dɛn we yu de it ɛn yu layf kin ɛp fɔ mek yu EPO lɛvɛl go ɔp smɔl. Bɔt dɛn fɔ du dɛn tin ya apat frɔm di advays we dɔktɔ gi dɛn ɛn nɔto fɔ tek di tritmɛnt in ples.

• Ɛksesaiz: Risach dɔn sho se we yu de ɛksesaiz ɔltɛm, we yu de du ɛksɛsayz, yu bɔdi de yuz mɔ ɔksijɛn. Dɔn yu bren kin tɛl yu bɔdi fɔ ‘mek mɔ EPO.’ Tin dɛn lɛk fɔ rayd baysikul, fɔ jok, ɛn fɔ swim na gud ɛgzampul fɔ dis kayn ɛksesaiz.
• Ayɛn we wi de it: Ayɔn na wan men tin we de mek di ɛmoglobin de insay wi rɛd blɔd sɛl dɛn. Dis ɛmoglobin na in de kɛr ɔksijɛn. We wi de tɔk bɔt it dɛn we gɛt ayɛn, wi min rɛd mit, eg yolk, ligɛm, ɛn ivin grɛn vɛjitebul lɛk spinach we wi gɛt na wi vilej. Tofu, siriɔs tin dɛn we gɛt ayɛn, flawa, ɛn bred gɛt ayɛn bak.

Apat frɔm dɛn tin ya, tin dɛn lɛk fɔ it balans it, fɔ drink bɔku wata, ɛn fɔ avɔyd fɔ smok kin fayn bak fɔ yu ɔl yu wɛlbɔdi, ɛn indaykt wan, yu EPO lɛvɛl.

Fɔ dɔn, tin dɛn we yu fɔ mɛmba

Erythropoietin (EPO) na wan rili imכtant כmon we de tεl wi bon mכro fכ ‘mek mכr rεd bכdi sεl dεm’.

Sɔntɛnde, wi bɔdi kin mek tumɔs rɛd blɔd sɛl, ɔ nɔ kin mek wi bɔdi. Dɛn tu tin ya kin mek pɔsin gɛt wɛlbɔdi prɔblɛm. Yu dɔktɔ kin chɛk di EPO we de na yu blɔd wit blɔd tɛst ɛn if nid de, i kin gi yu di rayt tritmɛnt. So, if yu gɛt sayn dɛn we de sho se yu nɔ gɛt blɔd (we yu taya, yu de shayn, yu nɔ de blo fayn), ɔ if yu gɛt prɔblɛm wit yu kidni, mek shɔ se yu go to dɔktɔ. Dɛn go ɛp yu di rayt we. Stay wit wɛlbɔdi!

` Erythropoietin, EPO, rεd bכdi sεl dεm, anemia, kidni, כmon, bon mכro