Yu blɔd prɛshɔn nɔ de kam dɔŋ ivin if yu tek mɛrɛsin? Lɛ wi lan bɔt di hyperaldosteronism.

Sɔntɛnde yu kin wɔnda se, ‘Wetin mek na di wɔl mi blɔd prɛshɔn nɔ go go dɔŋ ivin if a tek mɛrɛsin?’? Sɔm pipul dɛn gɛt di sem prɔblɛm. Sɔntɛnde, i nɔ kin izi fɔ kɔntrol dɛn blɔd prɛshɔn, ivin afta dɛn dɔn tek mɛrɛsin. Sɔntɛnde lɛk dis, wi nid fɔ tink if i go bi se sɔntin de we mek wi du dis. Tide, wi go tɔk bɔt wan sik wae kin at fɔ no sɔmtɛm, bɔt kin wɛl if dɛn trit am fayn. Dat na di sik we dɛn kɔl hyperaldosteronism .

Wetin na Hyperaldosteronism?

Fɔ tɔk am simpul wan, hyperaldosteronism na we yu adrenal gland dɛn de mek tumɔs pan wan ɔmon we dɛn kɔl aldosterone . Tink bɔt am dis we, aldosterone tan lɛk smɔl injinia we de kɔntrol wi blɔd prɛshɔn. I de ɛp fɔ mek wi blɔd prɛshɔn de di rayt lɛvɛl bay we i de rigul di lɛvɛl dɛn we di potashɔm ɛn sɔdiɔm de na wi bɔdi.

Naw yu go de wɔnda se, ‘Wetin na dɛn adrenal gland ya?’ Dɛn tin ya na pat pan wi ɛndokrin sistɛm . Dɛn tan lɛk smɔl smɔl faktri dɛn we de mek di difrɛn ɔmon dɛn we wi bɔdi nid fɔ wok ɛvride. Wi gɛt tu pan dɛn adrenal gland ya, we rili de ɔp wi kidni dɛn, lɛk kap.

Wetin na di kayn we aw pɔsin kin gɛt di sik we dɛn kɔl hyperaldosteronism?

Tu men kayn hayparaldosteronism de.

1. Praymari Hyperaldosteronism: Sɔntɛnde dɛn kin kɔl dis Conn’s syndrome . Wetin kin apin ya na dat sɔmtin de we nɔ fayn wit yu adrenal gland dɛnsɛf, we kin mek dɛn mek tumɔs aldosterone. Tink bɔt am lɛk se prɔblɛm de insay faktri ɛn dɛn de mek tumɔs tin.

2. Sεkכnd Hyperaldosteronism: Dis nכto prכblεm wit di adrenal gland dεm. Na prɔblɛm ɔdasay na yu bɔdi we de mek di adrenal gland dɛn de wok ɛn bigin fɔ mek mɔ aldosterone. Dis min se di faktri de wok ova tɛm bikɔs ɔf wan ɛksternal inflɔɛns.

Ilɛk aw i bi, di ɛnd rizɔlt na dat di aldosterone lɛvɛl na yu blɔd de go ɔp, we de mek yu blɔd prɛshɔn (haypa prɛshɔn) ɛn di potashɔm lɛvɛl na yu blɔd go dɔŋ. dis dכn we di potashכm de dכn dεn kכl am haypokalemia .

Udat dɛn kin afɛkt mɔ pan dis sik? Aw i kɔmɔn?

di hayperaldosteronism dεn kin si am mכst pan pipul dεm we ol bitwin 30 εn 50 ia.Dɔn bak, dis sik kin bɔku smɔl pan uman dɛn pas man dɛn.

I at fɔ mek di wan dɛn we de du risach tɔk klia wan aw dis kin apin, bikɔs sɔntɛnde dɛn nɔ kin no am di rayt we. Bɔt sɔm stɔdi dɛn sho se bitwin 5% ɛn 10% pan di pipul dɛn we gɛt ay blɔd prɛshɔn kin gɛt praymari hayparaldosteronism. Masta sabi bukman dɛn se lɛk 25% pan di pipul dɛn we gɛt ay blɔd prɛshɔn we nɔ de tek mɛrɛsin kin gɛt dis sik. So, i nɔ kɔmɔn so, nɔto so?

Wetin na di sayn dɛm fɔ Hyperaldosteronism?

Di sayn dɛm fɔ hyperaldosteronism kin difrɛn frɔm wan pɔrsin to ɔda pɔrsin, i kin dipen pan aw di sik tranga. Sɔm pipul dɛn nɔr kin gɛt ɛni sayn at ɔl , mɔr lɛk if de sik nɔr rili bad.

Bɔt di men ɛn kɔmɔn sayn fɔ dis sik na ay blɔd prɛshɔn (haypa prɛshɔn) , mɔ di ay blɔd prɛshɔn we nɔ kin izi fɔ kɔntrol ivin wit mɛrɛsin.

Apat frɔm dat, if yu gɛt ɔda sayn dɛm, bɔku tɛm dɛn kin kam bikɔs ɔf di mɔdaret to siriɔs ay blɔd prɛshɔn ɛn/ɔ di smɔl potashɔm lɛvɛl na di blɔd (hypokalemia).

Di sayn dɛm we kin apin bikɔs ɔf di ay blɔd prɛshɔn (haypa prɛshɔn):

• Ɛd we de at
• Diziz we pɔsin kin gɛt
• Vishɔn kin chenj
• I nɔ kin izi fɔ yu fɔ blo

Di sayn dɛm we kin apin bikɔs di potashɔm na di blɔd nɔ bɔku (haypokalemia):

• di mכsul dεm we wik - Insay sכm siriכs kes dεm, wan kכndyushכn we lεk tεmporari paralayz kin apin.
• Mɔsul dɛn de twitch ɔ twitch (mɔsul dɛn de swɛt) .
• Tingling ɛn numbness
• Taya
• Fɔ tɔsti pasmak (dɛn kɔl dis polydipsia) .
• Fɔ pis bɔku tɛm

Naw yu dɔn ɔndastand, bikɔs sɔm pan dɛn sayn ya kin kam pan ɔda sik dɛm, sɔmtɛm i kin tu let fɔ no dis.

Wetin kin mek dis apin?

di tin dεm we de mek di hyperaldosteronism de difrεn difrεn dipכnt if na praymar כ sεkכnd. Mek wi tek wan luk pan aw.

Di tin dɛn we kin mek pɔsin gɛt Praymari Hyperaldosteronism

As a bin dɔn tɔk bifo tɛm, Primary Hyperaldosteronism na prɔblɛm wit yu adrenal gland dɛnsɛf, we kin mek dɛn prodyuz tumɔs aldosterone.

di tin we kin mek dis apin pas ɔl na di tכmכro dεm we nכ de kכnεs we dεn kכl adrenal adenomas we de fכm na di adrenal gland dεm . Dis na smɔl smɔl tumbu dɛn we nɔ de du bad, bɔt dɛn kin mek di ɔmon we dɛn kɔl aldosterone kɔmɔt pasmak.

Apat frɔm dat, sɔm ɔda tin dɛn de we nɔ kin apin so ɔltɛm :

• Yunilateral adrenal hyperplasia - dis min se na wan adrenal gland nכmכ na wan sayd de swεla, i de big, εn i de mek mכr כmon dεm.
• adrenocortical carcinomas we de prodyuz aldosterone - Dis na kansa tכmכro dεm. Bɔt, dɛn nɔ kin bɔku.
• famili hayparaldosteronism tayp 1 - dis na kכndyushכn we de kכmכt frכm di mama εn papa to pikin dεm.

Di tin dɛn we kin mek pɔsin gɛt Sɛkɔndari Hyperaldosteronism

di men tin we kin mek yu gɛt sɛkɔndari haypa aldosteronism na we di blɔd we de rich yu kidni dɛn kin go dɔŋ .

Fɔ ɔndastand aw dis kin apin, yu nid fɔ no se di ɔmon we dɛn kɔl aldosterone na pat pan wan kɔmpleks chenj we gɛt ɔmon dɛn we de kɔntrol wi blɔd prɛshɔn. Tink bɔt am lɛk chen riakshɔn.

Dɛn kɔl dis sistɛm di renin-angiotensin-aldosterone sistɛm . I de wok lɛk dis:

1. We yu bɔdi no se blɔd prɛshɔn smɔl ɔ sɔdiɔm smɔl na yu blɔd, yu kidni dɛn kin pul wan ɛnzaym we dɛn kɔl renin .

2. dis renin de go εn kכnvכlt wan tin we dεn kכ l angiotensinogen (we de bifo angiotensin) we yu liva de mek to angiotensin I. (Angiotensin na כmon we de kכnstrikt wi bכdi vεsεl dεm.)

3. Neks, dis angiotensin I de bi angiotensin II .

4. fכ finish, na dis angiotensin II de kכnstrikt di bכdi vεsul dεm mכr εn i de mek di adrenal gland dεm fכ rilis di כmon we dεn kכl aldosterone .

Naw imajin, if fɔ sɔm rizin di blɔd we de go na di kidni dɛn go dɔŋ, di kidni dɛn kin tink se, ‘O, mi blɔd prɛshɔn dɔn go dɔŋ.’ afta dat dεn kin mistek mek dis rεnin-angiotensin-aldosterone sistεm aktibכt. di rizulεt na dat di lεvεl fכ aldosterone na di bכdi de inkrεs, pan כl we i nכ rili nid.

di tin dεm we kin mek di bכdi fכ fכm na di kidni dεm εn mek sεkכnd hayparaldosteronismNa sɔm pan dɛn:

• Obstruktiv rεnal atεri sik - lεk wata paip we klos.
• Renal haypatɛnshɔn
• di kכndishכn dεm we wata kin kכmכt na di bכdi (εdima) , fכ egzampl:
• At we nɔ de wok fayn
• Sirosis na di liva
• Nephrotic syndrome na wan sik we de ambɔg di kidni.

Aw yu kin no bɔt dis?

Dɔktɔ kin no if pɔsin gɛt aypaaldosteronism bay we i de du blɔd tɛst . Bɔt dɛn nɔ kin ɛva no se bɔku pipul dɛn gɛt dis sik bikɔs bɔku ɔda tin dɛn de we kin mek dɛn gɛt ay blɔd prɛshɔn ɛn tin dɛn we kin mek dɛn gɛt ay blɔd prɛshɔn.

Sɔm sayn dɛm wae kin sho se yu gɛt hyperaldosteronism na:

• Di ay blɔd prɛshɔn we nɔ de tek mɛrɛsin.
• Na dis na di rizɔlt frɔm yu ilɛktrɔlayt blɔd tɛst ripɔt:
• Mildly high sodium level (haypa natremia) .
• di magnεsium lεvεl lכw sכmtεm (haypomagnesemia) .
• Dɔn bak, di potashɔm we nɔ bɔku (haypokalemia) .

If yu dɔktɔ tink se yu kin gɛt hyperaldosteronism bay dɛn sayn ɛn simptom ya, i go mɔs ɔda fɔ du tu spɛshal blɔd tɛst: Plasma Renin Concentration (PRC) ɔ Plasma Renin Activity (PRA) .

• If yu gɛt Primary Hyperaldosteronism , yu PRC ɛn PRA lɛvɛl go smɔl pas aw i kin bi.
• If yu gɛt sɛkɔndari hayparaldosteronism , dɛn lɛvɛl ya go ay pas aw i kin bi.

Apat frɔm dat, yu kin nid bak fɔ mek dɛn du wan tɛst fɔ stɔp di aldosterone . Dis tɛst involv fɔ gi yu sɔm kayn sɔdiɔm (sɔl) bay yu mɔt ɔ tru salin (IV) injɛkshɔn fɔ sɔm tɛm. Dɔn, dɛn kin gɛda yu urine sɛmpul dɛn fɔ 24 awa ɛn dɛn kin mɛzhɔ di aldosterone we de insay da urine de na lɛbɔtri.

If dɛn tɛst ya kɔnfirm se yu gɛt hyperaldosteronism, yu dɔktɔ kin ɔda fɔ du ɔda tɛst fɔ no di kɔz. Fɔ ɛgzampul, CT skan (kɔmpyuta tomografi skan) fɔ si if wan tumbu we nɔ gɛt kansa de mek di haypa aldosteronism.Dɛn kin aks yu fɔ du wan tɛst fɔ tek pikchɔ .

Wetin na di tritmɛnt dɛm fɔ dis?

Di tritmɛnt fɔ di hyperaldosteronism dipen pan di tin we mek yu gɛt am, bɔt di men gol na fɔ kɔntrol yu blɔd prɛshɔn .

• Fɔ praymari hyperaldosteronism, we na wan sik we kin kam wit adrenal gland tumor, dɔktɔ dɛn kin se dɛn fɔ du ɔpreshɔn fɔ pul di tumor . Bɔt sɔm tɛm dɛn de, dɛn kin trit dɛn tumbu ya wit mɛrɛsin nɔmɔ. Ivin afta dɛn dɔn du di ɔpreshɔn, yu kin stil gɛt ay blɔd prɛshɔn, so yu go nid fɔ tek mɛrɛsin fɔ kɔntrol am.

• Dɛn kin trit sɛkɔndari hayparaldosteronism bay we dɛn kin kɔntrol yu blɔd prɛshɔn wit mɛrɛsin, ɛn dɛn kin trit di ɔndalayn kɔz bak (e.g., at sik) .

Bɔrku kayn mɛrɛsin de wae kin ɛp fɔ gɛt hyperaldosteronism:

• Spironolaktכn (Spironolaktכn - Aldaktכn®) .
• Eplerenɔn (Eplerenɔn - Inspra®) .
• Amilorid (Amilorid - Midamor®) ɛn di ɔda wan dɛn.

Wan tin we yu fɔ mɛmba na dat, if yu yuz mɛrɛsin dɛn we de blok aldosterone fɔ lɔng tɛm, lɛk Spironolactone , i kin mek man dɛn gɛt sɔm bad bad tin dɛn. fכ egzampl, di erectile dysfunction εn gaynecomastia kin apin. So, i impɔtant fɔ tɔk to yu dɔktɔ bɔt us mɛrɛsin go fayn fɔ yu, aw lɔng yu fɔ tek am, ɛn wetin go apin to yu.

Yu tink se dɛn go ebul fɔ stɔp dis?

Infakt, bɔrku tɛm, natin nɔr de wae yu kin du fɔ mek yu nɔr gɛt dis sik wae de mek yu gɛt hyperaldosteronism. Bikɔs i kin kam bikɔs di tin dɛn we de insay wi bɔdi kin chenj. Bɔt yu kin kɔntinyu fɔ gɛt wɛlbɔdi bay we yu de liv yu layf fayn, it fayn it dɛn, ɛn du ɛksɛsayz.

Wetin na di prɔgnosis fɔ dis kɔndishɔn?

di prכgnosis fכ hayparaldosteronism dipכnt pan di kכz.

• Praymari hayparaldosteronism , if dɛn no am kwik ɛn trit am fayn, bɔku tɛm i kin gɛt gud tin fɔ du . If dɛn pul wan tumbu, bɔku tɛm dɛn kin kɔntrol di sik.
• Sɛkɔndari HayparaldosterɔnismDi fiuja fɔ di sik de dipen pan aw dɛn kin kɔntrol di ɔndalayn mɛdikal kɔndishɔn (e.g., at sik, liva sik).

di men komplikashכn dεm we kin apin bikoz fכ di haypa aldosteronism na di kכdivaskyul εshyu dεm we kin kכz fכ hεy blכd prεshכn. Dɛn tin ya na:

• Atrial fibrillation - na wan at bit we nɔ de bit ɔltɛm.
• di lεft vεntrikulכr haypatrכfi - di wכl dεm na di lεft chεmba na di at de tik.
• At atak
• Strok

Na dat mek i rili impɔtant fɔ no dis sik kwik kwik wan ɛn gɛt di rayt tritmɛnt.

Ustɛm a fɔ go to dɔktɔ?

If dɛn dɔn no se yu gɛt hyperaldosteronism, yu fɔ go to yu dɔktɔ ɔltɛm fɔ mek shɔ se di mɛrɛsin we dɛn gi yu de wok fayn . I rili impɔtant bak fɔ fala wetin yu dɔktɔ tɛl yu fɔ du.

If yu gɛt ɛni nyu sik, ɔ yu notis se di sik dɔn chenj , tɛl yu dɔktɔ wantɛm wantɛm.

Di tin we impɔtant pas ɔl na dat, if yu gɛt ay blɔd prɛshɔn we nɔ de tek mɛrɛsin, tɔk to yu dɔktɔ bɔt wetin de mɔna yu, lɛk, "A kin gɛt hyperaldosteronism?" I kin ebul fɔ no aw yu sik ɛn tɛl yu fɔ du ɛni tɛst we yu nid fɔ du.

Mɛmba se bɔku tin dɛn de we kin mek pɔsin gɛt ay blɔd prɛshɔn. Hyperaldosteronism na jɔs wan pan dɛn. Di gud nyus na dat dis na sik we pɔsin kin mɛn.

Mɛsej we dɛn kin kɛr go na os

Okay, so a op se yu naw gɛt bɛtɛ ɔndastandin bɔt wetin wi bin de tɔk bɔt, Hyperaldosteronism. Na sɔm tin dɛn we yu fɔ mɛmba:

• hayperaldosteronism na di we aw di adrenal gland dεm de mek di כmon aldosterone pasmak .
• Dis kin mek yu blɔd prɛshɔn (haypa prɛshɔn) ɛn di potashɔm we de na yu blɔd go dɔŋ (haypokalemia) .
• tu men tכp dεm de: Praymari ( wan prכblεm wit di adrenal gland dεm sεf) εn Sεkכndari (adrenal gland stimulashכn bikoz fכ prכblεm כdasay).
• If yu gɛt ay blɔd prɛshɔn we mɛrɛsin nɔ de kɔntrol , yu fɔ sɔprayz bɔt dis.
• Dɛn kin no dis bay we dɛn de du blɔd tɛst .
• Di tritmɛnt na fɔ kɔntrol di blɔd prɛshɔn ɛn fɔ trit di rizin we mek dɛn gɛt am .
• If dɛn no ɛn trit am kwik, dɛn kin gɛt gud rizɔlt .

If yu gɛt ɛni ɔda kwɛstyɔn bɔt dis, nɔ fred fɔ aks yu dɔktɔ. Stay wit wɛlbɔdi!

` Hyperaldosteronism, Hyperaldosteronism, Aldosterone, Ay blɔd prɛshɔn, haypatɛnshɔn, Potashɔm, Adrenal gland dɛm, Kɔn in sindrom