Yu de gɛt strenj sayn dɛm bikɔs ɔf di lɔw kalsiɔm lɛvɛl na yu bɔdi? I kin bi se na haypoparatayroydism!

Sɔntɛnde, yu kin fil pen na yu bɔdi we yu nɔ ebul fɔ ɛksplen? Yu an ɛn fut dɛn kin swɛt? Ɔ yu jɔs de fil lɛk se yu skin jɔs de kray? Wan pan de rizin fɔ dɛn tin ya kin bi wan sik we dɛn kɔl hypoparathyroidism, we wi go tɔk bɔt tide. Nɔ wɔri, pan ɔl we dis na tin we nɔ kin apin so ɔltɛm, dɛn kin kɔntrol am if dɛn no am ɛn trit am fayn. Lɛ wi tɔk bɔt dis ditayli.

Wetin na Hypoparathyroidism?

Fɔ tɔk am simpul wan, haypoparatayroyd na we yu blɔd de mek tumɔs smɔl ɔ nɔ de mek Paratayroyd Ɔmon (PTH). dis כmon imכtant fכ rεgεl di lεvεl dεm fכ di kalsiכm εn fכsfכr na yu bכdi. So, we yu PTH lεvεl dεm dכn lכw, yu bכdi kalsiכm lεvεl dεm de dכn – wi kכl dis haypokalsiכ m – εn yu bכdi fכsfכr lεvεl dεm de go כp.

Dis sik kin de fɔ lɔng tɛm , we min se i kin las fɔ ɔl yu layf. Bɔt sɔntɛnde, i kin bɛtɛ bak fɔ sɔm tɛm.

So wetin na dɛn paratayroyd gland ya?

Imajin, na di fɔs pat na wi nɛk, we tan lɛk bɔtaflay, na de di Tayrɔyd Gland de. Biɛn da Tayrɔyd Gland de, 4 gland dɛn de, bɔku tɛm dɛn kin saiz lɛk smɔl pis. Dɛn kɔl dɛn tin ya Paratayroyd Gland dɛn . Dɛn tin ya na pat pan di Ɛndokrin Sistɛm we de mek ɔmon dɛn na wi bɔdi.

Sɔntɛnde, dɛn 4 gland ya kin de ɔdasay na di nɛk, chɛst, ɔ ivin nia di εsophagus. dεn kכl dεn tin ya εktopik paratayroyd gland dεm .

di men wok we dεn paratayroyd gland dεm ya de du na fכ mek paratayroyd כmon (PTH). dis PTH na in de mek di kalsiכm lεvεl na wi bכdi de di rayt lεvεl.

• If PTH dכn: di kalsiכm we de na di bכdi de dכn (Hypocalcemia).
• if PTH inkrεs: di kalsiכm we de na di bכdi de inkrεs (Hypercalcemia).

nכto dat nכmכ, bכt dis PTH כmon de εp bak fכ kכntrכl di lεvεl dεm fכ fכsfכr εn vaytam in D na di bכdi εn bon dεm.

Wetin na kalsiɔm? Wetin i de du fɔ wi bɔdi?

Kalsiɔm na impɔtant minral fɔ wi bɔdi. Yu no se bɔku pan di kalsiɔm we de na wi bɔdi kin de na wi bon dɛn? Bɔt sɔm kayn kalsiɔm fɔ de bak na di blɔd.

Lɛ wi luk sɔm impɔtant tin dɛn pas di kalsiɔm we de na di blɔd:

• I de ɛp wi nervɔs sistɛm fɔ wok .
• I de ɛp di mɔsul dɛn fɔ kɔntrakt ɛn rilaks . Dis na wetin de mek wi ebul fɔ muv wi an ɛn fut dɛn ɛn waka.
• We wi gɛt injuri ɛn blɔd, i kin ɛp fɔ mek di blɔd klɔt .
• I impɔtant fɔ mek wi at wok fayn .

Naw yu ɔndastand aw haypokalsiɔm (lɔ blɔd kalsiɔm) bikɔs ɔf haypoparatayroyd kin afɛkt bɔku tin dɛn. Kalsiɔm de bak fɔ mek di bon dɛn strɔng. Bɔt haypokalsiɔm na we di kalsiɔm we de na di blɔd de go dɔŋ, nɔto we di kalsiɔm we de na di bon dɛn go dɔŋ.

Yu tink se haypoparatayroydism kin mek di ilɛktrɔlayt nɔ balans?

Yɛs, na fɔ tru. Kalsiɔm ɛn Fɔsfɔr na tu kayn ilɛktrɔlayt dɛn . Ilektrolayt na minral dεm we gεt ilektrikal chaj na wi bכdi εn de kכntribyut fכ bכku imכtant wok dεm. pan haypoparatayroydism, di kalsiכm we de na di bכdi de dכn εn di fכsfכr de inkrεs, we de mek di εlektrolayt imbalans. I rili impɔtant fɔ kɔrɛkt dis.

Wan ɔda tin de bak. Magnɛsiɔm na ɔda impɔtant ilɛktrɔlayt. If di lɛvɛl we di magnɛsiɔm de na di blɔd go dɔŋ (Hypomagnesemia) , i kin bi bak wan tin we kin mek pɔsin gɛt haypoparatayroydism. Bikɔs magnɛsiɔm impɔtant fɔ mek di paratayrɔyd gland dɛn wok fayn fayn wan.

Wetin na di difrɛns bitwin Hypoparathyroidism ɛn Hyperparathyroidism?

Dɛn tu nem ya fiba smɔl, so dɛn kin mek pɔsin kɔnfyus. Insay mɛrɛsin, di prɛfiks "Hypo" min "lɛs" ɔ "nɔ inof." Di prɛfiks "Hyper" min "mɔ" ɔ "hay."

• Hypoparathyroidism: Di parathyroid gland dεm nכ de prodyuz inof parathyroid hormone (PTH), we de mek di kalsiכm lεvεl dεm na di bכdi dכn.
• Hyperparathyroidism: Di parathyroid gland dεm de mek tu mכch PTH, we de mek di kalsiכm we de na di bכdi go כp.

Simpul, nɔto so?

Udat kin gɛt dis sik we dɛn kɔl haypoparatayroydism?

Dis kin apin to big pipul ɛn smɔl pikin dɛn bak. Bɔt lɛk aw wi bin dɔn tɔk, dis na tin we nɔ kin apin so ɔltɛm .

• pan big pipul dεm: Dis kin kכz fכ aksidεnt damej pan di paratayroyd gland dεm we dεn de du כpεrayshכn na dεn nεk – fכ egzampl, tayroyd כpεrayshכn.
• Fɔ pikin dɛm: Bɔku tɛm, dis kin kam wit wan jɛnɛtik kɔndishɔn we dɛn kɔl DiGeorge Syndrome pan pikin dɛm.

Ivin na kɔntri lɛk Amɛrika, dɛn kin se dis sik nɔ kin afɛkt tu ɔndrɛd tawzin pipul dɛn. So na wi kɔntri, i kin ivin smɔl.

Wetin na di men tin dɛm wae kin mek pɔrsin gɛt haypoparathyroidism?

Bɔku rizin dɛn de fɔ dis.

• Di damej we di paratayroyd gland dɛn kin pwɛl: Dis na di tin we kin mek i apin mɔ. Na lɛk 75 pasɛnt (75%) panDi sik pipul dɛn kin gɛt dis sik we di gland dɛn kin pwɛl bay aksidɛnt we dɛn de du ɔpreshɔn pan dɛn nɛk ɔ tayroyd gland. Sɔntɛnde, dis sik kin apin sɔm ia afta di ɔpreshɔn. Bɔt bɔku tɛm, i kin bigin jɔs afta di ɔpreshɔn. Bɔrku tɛm, haypoparathyroidism wae kin apun dis kayn wae kin bi fɔ sɔm tɛm, bɔt pan sɔm pipul dɛm i kin bi fɔ ɔltɛm. I nɔ kin izi fɔ mek dɛn gɛt raytin tɛrapi fɔ pwɛl dɛn gland ya.

• di jεnεtik kכndishכn dεm: lεs dan tεn pasεnt (10%) pan di kεys dεm na di jεnεtik kכndishכn dεm. Di wan we kin bɔku pan dɛn tin ya na DiGeorge Syndrome . Dis na wan kromozom jεnεtik kכndishכn. di pikin dεm we dεn bכn wit dis sεndrכm nכ gεt paratayroyd gland dεm. So, bikɔs dɛn nɔ de mek PTH, dɛn gɛt krɛse hapoparatayroydism. Dɛn se lɛk 60% pan di pikin dɛn we gɛt haypoparatayroydism gɛt DiGeorge Syndrome. I kin kam bak wit ɔda jenɛtik sindrom wae gɛt fɔ du wit dɛf ɛn kidni sik.

• Autoimyun Diseases: Sɔntɛnde wi yon imyun sistɛm kin mistek atak di paratayroyd gland dɛm. Tayp 1 ɔtoimyun polyglandular sindrom na wan pan dɛn kayn sik ya. Dis kin mek yu gɛt haypoparatayroydizm we nɔ de dɔn. I kin kam bak bikɔs ɔf tin dɛn we dɛn kɔl Addison’s disease ɛn pernicious anemia .

• Infiltrative Disorders: Insay sɔm sik stet dɛm, tin dɛm lɛk ayɔn (lɛk na ɛmokromatosis) ɛn kɔpa (lɛk na Wilson in sik) kin gɛda na di paratayroyd gland dɛm. Dɔn bak, sɔm kansa mɛtastas kin mek dɛn gland ya nɔ wok fayn, ɛn dis kin mek dɛn gɛt haypoparatayroyd.

• di Lכw Magnesium Lεvεl: As wi bin dכn tכk, magnεsium implεnt fכ di paratayroyd gland dεm fכ wok fayn fayn wan. If di magnɛsium smɔl na di blɔd (haypomagnesemia) i kin mek pɔsin gɛt haypoparatayroydism. Dɛn kɔl dis funkshɔn haypoparatayroydism . dis kכndyushכn kin sכlv we di magnεsium lεvεl dεm kam bak.

Wetin na di sayn dɛm wae de sho se yu gɛt haypoparathyroidism?

Bɔrku tɛm, dis sik kin kam sloslo. So, de sayn dɛm kin rili shɔt. Sɔm pipul nɔr kin ivin no se dɛn gɛt dis sik fɔ lɔng lɔng tɛm.

Dis na di sayn dɛm wae yu kin si in jɛnɛral:

• Tingling na di lip, finga tip, ɛn fut finga dɛn.
• Mɔsul dɛn we de kramp.Yu mɛmba se sɔntɛnde yu kin gɛt ia na yu leg na nɛt? Tin dɛm lɛk dat, bɔt if i kin apin ɔltɛm, i kin bi sayn fɔ dis kayn kalsiɔm we nɔ de.
• Di mɔsul dɛn we de spam (Tetany).
• Pɔsin we de fil pen na di bɛlɛ.
• "Brein fכg" na wan kכndishכn we yu kin gεt difεlεnt fכ kכnsantreyt εn fil sכmtεm disoriented.
• Di at bit we nɔ de bit ɔltɛm (Aritmia).
• Nail dɛn we kin brok brok.
• Dray ia ɛn dray, skel skin.
• Di we aw katarakt de apin.
• We di tut inɛmel wik na pikin dɛn.

Aw dɔktɔ dɛn kin no dis sik?

Dɛn kin sɔprayz ɛn kɔnfyus se pɔsin gɛt haypoparatayroyd we dɛn du tɛst sho se di pɔsin in blɔd kalsiɔm ɛn paratayroyd ɔmon (PTH) nɔ bɔku.

Bikɔs di sayn dɛm nɔr kin so klia, sɔmtɛm dɔktɔ dɛm kin no dis sik "incidentally." Dat min se, dɛn kin jɔs bigin fɔ luk fɔ am we dɛn si smɔl kalsiɔm na di blɔd we dɛn de du rutin blɔd tɛst fɔ ɔda sik.

If dɛn kɔnfyus se pɔsin gɛt smɔl PTH ɔmon ɛn kalsiɔm lɛvɛl na in blɔd tu tɛm insay siks mɔnt, dɛn kin tek am se na chronic hypoparathyroidism .

Us kayn tɛst dɛn kin du fɔ dis?

If yu gɛt dɛn sik ya, yu dɔktɔ go du yu bɔdi ɛgzam ɛn aks bɔt yu sik, famili mɛdikal istri, ɛn di mɛrɛsin dɛn we yu de tek.

Apat frɔm dat, dɛn kin du wan ɔ mɔ pan dɛn tɛst ya:

• Paratayroyd ɔmon (PTH) blɔd tɛst.
• Tɛst fɔ di blɔd we gɛt kalsiɔm.
• Fɔsfɔr blɔd tɛst.
• Magnɛsiɔm blɔd tɛst.
• 24 awa urine test: Dis de sho aw bɔku kalsiɔm de kɔmɔt na di urine.

Sɔntɛnde, yu dɔktɔ kin ɔda fɔ du ɔda tɛst fɔ chɛk fɔ mɔ siriɔs sayd ɛfɛkt we dis sik kin kam wit. Fɔ ɛgzampul:

• Ilɛktrokardiogram (ECG ɔ EKG): I de chɛk fɔ si if di at nɔ de rit ɔltɛm.
• Kɔmpyuta tomografi (CT) skan: Dɛn de chɛk fɔ si if di kalsiɔm dɔn de na di bren (Brain Calcifications).

Aw dɛn kin trit dis?

Di men gol fɔ tritmɛnt fɔ haypoparatayroydism na fɔ ridyus di simptom dɛm ɛn mek di lɛvɛl dɛm fɔ di kalsiɔm ɛn ɔda minral dɛm na yu bɔdi kam bak to di kɔrɛkt lɛvɛl.

Dɛn kin du dɛn tin ya as tritmɛnt:

• Fɔ gi Calcium Carbonate ɛn Vitamin D sɔpɔtmɛnt dɛn:Bɔrku pipul dɛm wae gɛt haypoparatayroydism go nid fɔ tek kalsiɔm ɛn vaytamɛn D pils ɔ wata fɔ di res ɔf dɛn layf. Dis na di men ɛn fɔs layn fɔ trit dis sik. Vitamin D impɔtant fɔ mek wi bɔdi tek di kalsiɔm fayn fayn wan. So if yu gɛt haypoparatayroydism, yu go nid fɔ tek dɛn tu supamakit ya.
• Di it we gɛt bɔku kalsiɔm ɛn we nɔ gɛt bɔku fosfɔr: Yu dɔktɔ kin advays yu fɔ it mɔ tin dɛn we gɛt kalsiɔm (milk, chiz, yogɔt, grɛn vɛjitebul) ɛn ridyus it dɛn we gɛt bɔku fosfɔr (mit we dɛn dɔn prosɛs, drink lɛk kola). Bɔt bikɔs i nɔ kin izi fɔ gɛt inof kalsiɔm frɔm it nɔmɔ, i kin nid fɔ tek sɔpɔtmɛnt dɛn.
• Paratayroyd ɔmon (PTH) injɛkshɔn: If kalsiɔm ɛn vaytamɛn D sɔpɔtmɛnt nɔmɔ nɔ de kɔntrol yu sik, yu dɔktɔ kin disayd fɔ gi yu paratayroyd ɔmon (PTH) injɛkshɔn.

Ɛni bad tin de we di tritmɛnt kin du?

Yɛs, sɔntɛnde if di vaytamɛn D ɛn kalsiɔm we dɛn gi as tritmɛnt tu bɔku, di kalsiɔm we de na di blɔd kin bɔku. Dɛn kɔl dis aypa kalsiɔm . Dis kin ambɔg di bɔdi bak. So, yu nid fɔ du blɔd tɛst ɔltɛm fɔ si if yu tritmɛnt de wok fayn ɛn yu kalsiɔm lɛvɛl kɔrɛkt.

Na smɔl risk de fɔ mek yu gɛt wan kayn bon kansa we dɛn kɔl ɔstiosarkoma we yu yuz paratayrɔyd ɔmon (PTH) injɛkshɔn fɔ lɔng tɛm. So, dɔktɔ dɛn kin se dɛn fɔ gi dis injɛkshɔn pan tin dɛn we rili siriɔs, we ɔda tritmɛnt dɛn nɔ dɔn wok fayn.

Wetin na de risk factor fɔ dis sik?

Bɔku tin dɛn de we kin mek pɔsin gɛt aypoparatayroydism:

• Bikɔs dɛn bin dɔn du ɔpreshɔn pan in nɛk ɔ tayroyd i nɔ tu te yet.
• Famili histri fɔ paratayrɔyd gland sik dɛn.
• Fɔ gɛt sɔm ɔtoimyun sik dɛm we de afɛkt di ɛndokrin sistɛm, lɛk di sik we dɛn kɔl Addison.

Wetin na di prɔgnosis fɔ dis kɔndishɔn?

Di luk fɔ haypoparatayroydism kin jɔs fayn, mɔ if dɛn no di sik kwik ɛn dɛn bigin fɔ trit am fayn fayn wan.

Bɔt if dis sik kin mek tin dɛn lɛk katarakt, di bren we gɛt kalsifikeshɔn, ɛn di chenj na di tit, i nɔ kin izi fɔ mek dɛn chenj dɛn. Na dat mek i impɔtant fɔ no di pɔsin kwik kwik wan.

Aw lɔng dis tin go las?

Bɔrku tɛm, haypoparatayroydism na wan sik wae nɔr de dɔn, we min se i kin de fɔ ɔl yu layf. כltu, haypoparatayroydism kin bi fכ sכm tεm bak bikoz fכ sכm kכz dεm (e.g., magnεsium dεfichεshכn, fכ sכm tεm afta dεn כpεrayshכn).

Wetin na di prɔblɛm dɛn we kin kam wit dis?

If dɛn nɔ trit di haypoparatayroydizm fayn fayn wan, difrɛn prɔblɛm dɛn we kin tek lɔng tɛm kin apin:

• Di prɔblɛm dɛn we kin apin we di kidni de wok.
• Kidni ston dɛn.
• Katarakt we pɔsin kin gɛt.
• Di kalsiɔm we de na difrɛn pat dɛn na di bren.

Dis sik, mɔ pan pikin dɛm, kin mek dɛn gɛt prɔblɛm lɛk:

• Pɔsin we nɔ de gro fayn.
• Dental ishu dɛn.
• Slow mental divεlכpmεnt.

I rili impɔtant fɔ no se if di kalsiɔm lɛvɛl na di blɔd go dɔŋ wantɛm wantɛm ɛn bad bad wan (Acute Hypocalcemia), if dɛn nɔ trit am kwik, i kin mek pɔsin gɛt prɔblɛm dɛn we kin mek pɔsin in layf de pan denja lɛk fɔ sik ɛn i kin at fɔ blo bikɔs ɔf di laryngeal spasm . If yu gɛt dɛn sayn ya (e.g., yu mɔsul dɛn de twitch bad bad wan, yu fɔ kɔnvulshɔn), yu fɔ go na di ɔspitul we de nia yu wantɛm wantɛm.

Ustɛm yu fɔ go to dɔktɔ?

• If yu gɛt sɔm sayn dɛm wae yu tink se kin bi haypoparatayroyd, mek shɔ se yu go to dɔktɔ.
• If dɛn dɔn ɔlrɛdi no se yu gɛt haypoparatayroydism, yu fɔ de chɛk yu blɔd kalsiɔm lɛvɛl ɔltɛm lɛk aw yu dɔktɔ tɛl yu fɔ mek shɔ se yu de gɛt di kɔrɛkt tritmɛnt.
• As wi bin dɔn tɔk, if yu gɛt sayn dɛn we de sho se yu gɛt akyu haypokalsiɔm, lɛk we yu mɔsul dɛn de shek shek wantɛm wantɛm ɔ yu de sik , go na di ɔspitul we de nia yu wantɛm wantɛm.

Di impɔtant tin dɛn we yu nid fɔ mɛmba (Take-Home Message) .

Hypoparathyroidism na wan sik we nɔ kin apin so ɔltɛm, bɔt dɛn kin trit am ɛn dɛn kin ebul fɔ kɔntrol am . Sɔntɛnde, de sik kin bi tin wae nɔr kin no bɔt ɛn i nɔ kin izi fɔ no. So, i impɔtant fɔ tɛl yu dɔktɔ if yu gɛt ɛnitin we kin mek yu gɛt dis sik (fɔ ɛgzampul, if yu jɔs dɔn du ɔpreshɔn pan yu nɛk ɔ if pɔsin na yu famili gɛt paratayroyd sik).

Sɔm simpul blɔd tɛst kin chɛk yu paratayrɔyd ɔmon (PTH) ɛn di kalsiɔm lɛvɛl. If yu no dis sik kwik, yu kin stat di rayt tritmɛnt, mek yu nɔr gɛt prɔblɛm, ɛn liv wɛl bɔdi layf. So, nɔ panik, bɔt na fɔ no bɔt dis. If yu gɛt ɛnitin we de mɔna yu, nɔ shek fɔ tɔk to yu dɔktɔ.

` Haypoparatayroydism, Haypoparatayroydism, Paratayroyd gland dɛm, Paratayroyd ɔmon, PTH, Kalsiɔm, Haypokalsiɔm, Fɔsfɔr, Vitamin D, Ilɛktrɔlayt, Simptom dɛm, Tritmɛnt