Yu de gɛt fat we de na difrɛn pat dɛn na yu bɔdi? Mek wi lan bɔt Lipodystrophy!

Yu dɔn ɛva si, ɔ ɛkspiriɛns, we fat kin lɔs wantɛm wantɛm na sɔm pat dɛn na yu bɔdi, ɔ we fat kin bɔku na ɔda say dɛn we yu nɔ want? Sɔntɛnde, dis kin bi tin we pɔsin nɔ go ebul fɔ imajin. Tide wi go tɔk bɔt dis sem kɔndishɔn. We wi de tɔk bɔt mɛrɛsin, dɛn kɔl dis Lipodystrophy . Nɔ wɔri, pan ɔl we di nem go tan lɛk se i strenj, lɛ wi tɔk bɔt am simpul wan.

Wetin na Lipodystrophy?

Fɔ tɔk am simpul wan, Lipodystrophy na we di adipose tisu we de lɔs ɔl ɔ sɔm pat pan am, we wi kin kɔl "fat," na sɔm eria dɛn, ɔ di abnɔmal we di fat kin gɛda na difrɛn say dɛn na di bɔdi.

Imajin se yu de lɔs yu wet na sɔm pat dɛn na yu bɔdi, lɛk yu an ɛn yu fut, ɛn yu de gɛt bɔku fat na sɔm say dɛn lɛk yu fes ɛn yu nɛk. Dis na wetin kin apin na Lipodystrophy. difrεn tכp dεm de fכ dis kכndyushכn, sכm pan dεm na jεnεtik (i.e., sכmtin we dεn bכn wi wit), כda wan dεm de divεlכp leta as a rizulεt fכ כda mεdikal kכndyushכn dεm. Ɛni kayn kin afɛkt pipul dɛn difrɛn we ɛn gɛt difrɛn sayn dɛn.

Wetin mek fat (adipose tissue) impɔtant to wi bɔdi?

Naw yu go de tink se, "Di smɔl fat we yu gɛt, na di mɔ i go bɛtɛ." Bɔt fɔ tru, di adipɔs tisu de du bɔku impɔtant wok dɛn na wi bɔdi. Tek wan luk:

• εnεji we wi de kip: Na insay dεn fεt tisu dεm ya di εkstra kalori we wi de gεt frכm di it we wi de it de stכr as enεji.
• Fɔ protɛkshɔn: I de protɛkt difrɛn pat dɛn na wi bɔdi lɛk kusɛn.
• Fɔ mek wi kɔntinyu fɔ wam: I de mek di bɔdi wam ɛn protɛkt wi frɔm di kol ples.
• di ɔmon we de kɔmɔt: Bɔku impɔtant ɔmon dɛn lɛk Lɛptin de kɔmɔt ɛn kɔmɔt na di blɔd.
• Fɔ kɔntrol inflamɛns: I de ɛp bak fɔ kɔntrol inflamɛns na di bɔdi.

so, we dis fεt tisu dכn lכs כ dכn dכn abnכmal bikoz fכ lipodystrophy, nכto nכmכ wi apiyans de chenj, bכt imכtant mεtabolik fכnshכn dεm na di bכdi de disrupt bak. Bɔrku pipul dɛm wae gɛt lipodystrophy kin gɛt sik dɛm lɛk dayabitis ɛn gɛt abnɔmal blɔd kɔlɔstrel lɛvɛl.

Yu tink se kayn lipodystrophy de?

Yes, Lipodystrophy kin sheb to tu men kayn: jεnεtik εn akwyayz.

Tayp dɛm fɔ Jɛnɛtik Lipodistrofi

dis na inhεrit, dat na di kayn dεm we de apin bikoz fכ di jεnεtik mכtεshכn.

• Kɔnjɛnital Jɛnɛral Lipodistrofi (CGL): Dis na Berardinelli-Seip sindrom.Dɛn kin kɔl am bak. Dis na tin we nɔ kin apin so ɔltɛm. Insay dis, di bɔdi fat kin lɔs ɔlmost ɔ bɔku pan am. Dis kin apin bikɔs ɔf wan jenɛtik dɛfɛkt we kin de we dɛn bɔn am. Bɔrku tɛm, dɛn kin no dis sik insay di fɔs ia wae pɔrsin de liv.
• Familial Partial Lipodystrophy (FPLD): Dis na jεnεtik kכndyushכn bak. Bɔt bɔku tɛm, dɛn kin no se i gɛt am leta na layf. pan dis kכndyushכn, di pikin de lכs fεt mכtalman na in leg εn an, εn i de gɛda mכr fεt na in fes εn nεk.

Di kayn Lipodystrophy we dɛn kin gɛt

Dɛn kayn tin ya kin apin afta dɛn bɔn wi ɛn we wi de liv fɔ difrɛn rizin dɛn.

• Acquired Generalized Lipodystrophy (AGL): Dɛn kin kɔl dis sik bak Lawrence syndrome , dis kin mek yu nɔ gɛt bɔku fat, bɔku tɛm na yu fes, nɛk, yu an, ɛn yu leg. Dis fat we de lɔs kin apin kwik kwik wan, fɔ sɔm wiks, ɔr smɔl smɔl fɔ sɔm mɔnt ɔ ia. Bɔku tɛm, i kin bigin we i smɔl ɔ we i yɔŋ, bɔt i kin apin ɛni ej. Bɔku tin dɛn de we kin mek pɔsin gɛt AGL.
• Acquired Partial Lipodystrophy (APL): Dɛn kin kɔl am bak Barraquer-Simons syndrome , dis sik kin mek di fat we de na in fes, nɛk, an, ɛn chɛst nɔ de igen smɔl smɔl we i smɔl. Sɔm pipul dɛn kin gɛt bɔku fat bak na say dɛn lɛk dɛn bɛlɛ, dɛn leg, ɛn dɛn bɔdi. Bɔku tɛm APL kin gɛt fɔ du wit ɔtoimyun kɔndishɔn dɛn .
• Highly active antiretroviral therapy (HAART)-induced lipodystrophy (LD-HIV): Dis kayn lipodystrophy kin apin to pipul dɛm we gɛt di human immunodeficiency virus (HIV) afta dɛn dɔn gɛt highly active antiretroviral therapy (HAART) we inklud HIV-1 protease inhibitors . Di kayn we aw dis sik kin apin kin dipen pan aw di tritmɛnt kin tranga ɛn aw lɔng i kin tek. Bɔku tɛm, pipul dɛn we gɛt LD-HIV kin gɛt smɔl smɔl fat we de kɔmɔt na dɛn an, dɛn leg, ɛn fes. Sɔm pipul dɛn kin gɛt bɔku fat bak rawnd dɛn fes, nɛk, ɔp bak, ɛn dɛn wes.
• Localized Lipodystrophy: Dis na we di fεt de lכs na כnli sכm pat na di bכdi. Fɔ ɛgzampul, dis sik kin apin we dɛn injɛkt mɛrɛsin (lɛk insulin) na di sem say bɔku bɔku tɛm. I tan lɛk smɔl dimp, bɔt bɔku tɛm di skin we de oba am nɔ kin afɛkt.

Lipodystrophy ɛn Lipoatrophy na di sem tin?

Lipodystrophy na jεnarכl tεm fכ di abnכmal distribushכn fכ fεt. I gɛt fɔ du bak wit Lipoatrophy , we min se yu de lɔs fat. Sɔm sayɛnsman ɛn dɔktɔ dɛn kin yuz dɛn tu wɔd ya fɔ tɔk bɔt di sem sik. Fɔ tɔk am simpul wan, Lipoatrophy na wan smɔl pat pan Lipodystrophy.

Udat dɛn kin afɛkt mɔ pan dis sik? Aw i kɔmɔn?

Bɔku kayn lipodystrophy kin bigin we dɛn smɔl, bɔt di kayn we dɛn we dɛn kin gɛt kin apin bak pan big pipul dɛn.

wit di eksepshכn fכ HAART-induced lipodystrophy (LD-HIV) , כda kayn akwyayz lipodystrophy kin afekt uman dεm mכr. Bikɔs HIV infɛkshɔn kin bɔku pan man dɛn, LD-HIV kin bɔku pan man dɛn bak.

Jɛnɛral wan, lipodystrophy nɔ kin apin so ɔltɛm . כltu, di fכm dεm we dεn kin gεt (layf) fכ lipodystrophy de kam kכmכn biכs fכ di sayd ifekt dεm fכ sכm mεdikeshכn dεm.

Aw lipodystrophy kin afɛkt mi bɔdi?

Ɛni kayn lipodystrophy kin afɛkt di bɔdi difrɛn we, bɔt tu men tin dɛn de we kin apin: we di adipose tisu kin lɔs ɛn we di ɔmon we dɛn kɔl leptin nɔ de .

Di ifekt we di adipose tisu we de lɔs pan di bɔdi

Wi fat tisu na sɛl dɛn we dɛn kɔl adiposayt . εvri adiposyt sεl gεt lεk 90% lipid dכplεt dεm. dis adiposyt dεm de stכr fεt (triglisεrayd). we dεn fεt sεl dεm ya dεm dεm bikoz fכ lipodystrophy, dεn nכ kin ebul fכ stכr fεt fayn fayn wan.

Sɔm kes dɛm we gɛt Lipodystrophy, dis fat we dɔn lɔs kin de dipɔsit kɔrɛkt wan na ɔda tisu dɛm na wi bɔdi, fɔ ɛgzampul, na di liva, pankrias, ɔ di mɔsul tisu dɛm. Dis kin mek yu gɛt wɛlbɔdi prɔblɛm lɛk:

• Fat liva sik / epatik steatosis
• insulin rεsistεns εn εlevεt insulin lεvεl na di bכdi (hyperinsulinemia) .
• Dayabitis (Dayabetes Mɛlitɔs) .
• di lεvεl dεm we di triglisεrayd dεm na di bכdi de go כp (hypertriglyceridemia) .
• Pankriaytis we gɛt sik
• Mεtabolik sεndrכm
• Koronari at sik

Bɔt mɛmba se nɔto ɔlman we gɛt lipodystrophy go gɛt dɛn kayn tin ya. Sɔm kin gɛt fɔm wae nɔr kin pasmak, wae ɔda wan kin gɛt wae tranga pasmak.

Efεkt dεm we Lεptin Dεfisiεns Gεt pan di Bכdi

As pipul dɛn we gɛt lipodystrophy de lɔs dɛn fat tisu, dɛn kin lɔs sɔm ɔmon dɛn bak, mɔ di ɔmon we dɛn kɔl lɛptin .

Lɛptin na ɔmon we wi fat tisu de mek. I de ɛp wi fɔ gɛt nɔmal bɔdi wet fɔ lɔng tɛm. Yu no aw fɔ du am? Na bay we i de mek wi fil ful ɛn kɔntrol wi angri. Sayɛnsman dɛn stil de du risach bɔt lɛptin. Dɛn biliv se lɛptin de afɛkt wi mɛtabolism , di wok we di ɛndokrin sistɛm de du , ɛn di we aw di imyun sistɛm de wok.

Pipul dɛm wae gɛt lipodystrophy kin gɛt di lɛptin lɛvɛl we kin go dɔŋ, we kin mek dɛn angri pasmak, dɛn nɔr kin ebul fɔ gɛt insulin, ɛn ɔda kayn wɛl bɔdi prɔblɛm.

Wetin na di sayn dɛm wae de sho se yu gɛt lipodystrophy?

Bikɔs bɔku kayn lipodystrophy de, di sayn dɛm bak kin rili difrɛn.

Di sayn we kin apin mɔ na we di fat kin lɔs klia wan ɛn we kin kɔntinyu fɔ de na sɔm pat dɛn na di bɔdi, ɛn di sem tɛm, di fat kin gɛda we nɔmal ɔ we i nɔ want na ɔda say dɛn na di bɔdi.

Fɔ ɛgzampul, pipul dɛn we gɛt acquired partial lipodystrophy (APL) kin lɔs fat smɔl smɔl na dɛn fes, nɛk, an, ɛn chɛst we dɛn smɔl. Sɔm pipul dɛm wae gɛt APL kin gɛt pasmak fat bak na say dɛm lɛk dɛn bɛlɛ, dɛn leg, ɛn dɛn bɔdi.

Dipen pan di kayn lipodystrophy wae yu gɛt ɛn yu ej, yu nɔr kin notis ɛni big wɛl bɔdi prɔblɛm fɔ lɔng lɔng tɛm. Bɔt bɔku kayn lipodystrophy kin mek di blɔd kɔlɔstrel, triglisɛrɛyd, ɛn shuga (glukɔs) lɛvɛl go ɔp. Yu dɔktɔ kin no dɛn tin ya wit blɔd tɛst we yu kin du ɔltɛm, lɛk lipid panɛl ɛn bɛsik mɛtabolik panɛl .

Sɔm kayn lipodystrophy, mɔ di pat pan di lipodystrophy, kin tranga fɔ no. So, i impɔtant fɔ go to dɔktɔ if yu ɔ yu pikin gɛt nyu sik ɔ if wan sik we dɔn de de wɔs, ilɛk wetin mek yu gɛt am.

Wetin na di tin dɛm wae kin mek pɔrsin gɛt lipodystrophy?

di tin dεm we kin mek yu gεt lipodystrophy kin difrεn dipכnt if na jεnεtik כ we dεn gεt am.

Di tin dɛn we kin mek pɔsin gɛt Jɛnɛtik Lipodistrofi

di jεnεtik fכm dεm fכ lipodistrofi – we na di kכnεnital jεnaral lipodistrofi (CGL) εn famili pat pan di lipodystrofi (FPLD) – na sכm jεnεtik mכtεshכn dεm de kכz am .

jεnεtik mכtεshכn na chenj na wi DNA sikεns. di sikyud we wi de du DNA na in de gi wi sεl dεm di infכmeshכn we dεn nid fכ du dεn wok. So, if pat pan dis DNA sikεns nכ kכmplit כ damej, wi kin divεlכp sכmtεm dεm fכ wan jεnεtik sik.

• di kכz dεm fכ kכnεjital jεnaralized lipodystrophy (CGL): di CGL tayp 1 to 4 de kכz bay mכtεshכn insay di jin dεm AGPAT2, BSCL2, CAV1 , εn CAVIN1 . dis jin dεm imכtant fכ di growth εn fכnshכn fכ di fεt-stכr sεl dεm (adiposocytes) insay wi fεt tisu. di mכtayshכn dεm na dεn jin dεm ya de afekt di strכkchכ εn di wok we di adiposyt dεm de du. pikin we gεt CGL kin gεt dεn jin mכtεshכn ya frכm in mama εn papa. Ivin if dɛn mama ɛn papa ɔl tu gɛt wan kɔpi fɔ di jin we dɔn chenj, bɔku tɛm dɛn nɔ kin sho di sayn dɛn.
• di tin dεm we de mek di famili pat pan di lipodystrophy (FPLD): di mכtεshכn dεm we de insay sεvεra jin dεm kin mek FPLD. Di wan we kɔmɔn pas ɔl na LMNA.Wan muteshon na wan jin we dɛn kɔl LMNA. di LMNA jin εn כda jin dεm we de involv insay FPLD de instrכkt adiposyt dεm fכ stכr fεt εn mek difrεn protin dεm we imכtant fכ stכr fεt. if mכtεshכn apin insay εni wan pan dεn jin dεm ya, di growth, strכkchכ, כ fכnshכn fכ di adiposyt dεm de afekt bad bad wan. כl di kes dεm fכ FPLD de inhεrit insay wan כtosom dכminant patεn . Dis min se if yu gɛt wan kɔpi fɔ di jin we dɔn chenj na ɛni sɛl, na in go du fɔ mek yu gɛt di sik. Sɔntɛnde, pɔsin we gɛt FPLD kin gɛt di muteshon frɔm wan pan dɛn mama ɛn papa we di sik afɛkt. Ɔda tɛm dɛn, dɛn kin kam bikɔs ɔf nyu, random mutations na di jin, ɛn dɛn kin apin ivin if nɔbɔdi na di famili nɔ bin dɔn gɛt dis sik bifo.

Di tin dɛn we kin mek pɔsin gɛt Acquired Lipodystrophy

Acquired lipodystrophy kin bi bikɔs ɔf mɛrɛsin, ɔtoimyun riakshɔn , ɔ idiopathic kɔz . Pan ɔl we no dairekt jɛnɛtik bies nɔ de fɔ akwyayz lipodystrophy, sɔm risach pipul dɛn biliv se sɔm pipul dɛn kin gɛt jɛnɛtik prɛdispɔzishɔn fɔ gɛt akwyayz lipodystrophy.

• Di tin dɛn we kin mek pɔsin gɛt Acquired Generalized Lipodystrophy (AGL): AGL kin apin afta infɛkshɔn ɔ afta sik na di imyun sistɛm. Infεkshכn dεm we dεn bin dכn lεk wit AGL inklud:
• Chikinpoks (Chikinpoks / varicella) .
• Mizɛl
• Kɔf we de mek pɔsin kɔf (pertussis) .
• Difteria we pɔsin kin gɛt
• Nyumonia
• Osteomyelitis we gɛt di sik
• Mononucleosis (Mononucleosis / wan sik we dɛn kɔl mono) .

I nɔ shɔ se yu go gɛt AGL jɔs bikɔs yu gɛt dɛn infɛkshɔn ya.

di כtoimyun kכndishכn dεm we de asai wit AGL inklud:

• Awtoimyun tayroyditis
• Autoimyun epataytis we pɔsin kin gɛt
• Juvenail dɛmatomyositis we dɛn kin gɛt
• Rimatɔyd at at sik
• Di sik we dɛn kɔl Sjogren in sindrom
• Awtoimyun ɛmolaytik anemia

If yu gɛt dɛn imyun sistɛm sik ya, dɛn nɔ go se yu go rili gɛt AGL.

Bɔku tɛm, dɛn nɔ kin ebul fɔ no di tin we mek AGL de (idiopathic).

• Di tin dɛn we kin mek pɔsin gɛt Acquired Partial Lipodystrophy (APL): Sayɛnsman dɛn biliv se APL kin kam bikɔs wi imyun sistɛm kin mistek pwɛl di fat sɛl dɛn. Mɔ pas 80% pan di pipul dɛm we gɛt APL gɛt Kɔmplimɛnt 3 na dɛn blɔd.wan lכw lεvεl de fכ wan protin we dεn kכl kompliment fכktכ. dis protin de nכmal fכ involv insay wi imyun sistεm in rεspכns. Bɔku tɛm pipul dɛn we gɛt APL kin gɛt wan ɔtoantibodi we dɛn kɔl kɔmplimɛnt 3-nɛfritik faktɔ na dɛn blɔd. כtoantibodi na wan protin we de insay di imyun sistεm we de mistek atak εn pwεl di hεlty tisu.

• Di tin dɛn we kin mek pɔsin gɛt ayli aktif antiretroviral therapy (HAART)-induced lipodystrophy (LD-HIV): Sayɛnsman dɛn stil nɔ shɔ wetin mek HAART, we gɛt HIV-1 protease inhibitors, kin mek pɔsin gɛt lipodystrophy.

Di gud nyus na dat, bɔrku pipul dɛm wae kin bigin fɔ gɛt HIV tritmɛnt naw nɔr kin wɔri tumɔs bɔt lipodystrophy, bikɔs nyu HIV mɛrɛsin kin mek di sik nɔr kin apun.

Aw yu go no if yu gɛt lipodystrophy?

If yu gɛt sayn dɛm fɔ lipodystrophy, yu dɔktɔ go du yu bɔdi ɛgzam, aks yu bɔt yu mɛdikal istri ɛn yu famili mɛdikal histri, dɔn ɔda sɔm tɛst dɛm fɔ kɔnfirm di sik ɛn fɔ si if ɔda tin de fɔ yu simptom dɛm.

Us tɛst dɛn kin yuz fɔ no if pɔsin gɛt lipodystrophy?

Yu dɔktɔ kin ɔda fɔ du sɔm tɛst fɔ no if yu gɛt lipodystrophy ɛn/ɔ fɔ si if ɔda tin dɛn de we kin mek yu gɛt di sik. Dɛn tin ya na:

• Full-body MRI (Magnetic Resonance Imaging) scan: MRI de yuz big magnet, redio wev, ɛn kɔmpyuta fɔ mek ditayli pikchɔ dɛn bɔt di ɔgan dɛn ɛn ɔda tin dɛn we de insay yu bɔdi. Yu dɔktɔ kin ɔda dis tɛst fɔ no aw di fat we de na yu bɔdi ɛn aw i de sheb.
• Comprehensive Metabolic Panel: Dis na blɔd tɛst we de mɛzhɔ 14 difrɛn tin dɛn na yu blɔd. I de gi impɔtant infɔmeshɔn bɔt yu bɔdi in kemikal balans ɛn mɛtabolism. Di dɔktɔ go luk spɛshal wan pan yu blɔd shuga (glukɔs) lɛvɛl ɛn di ɛnzaym dɛn na yu liva .
• Lipid Panel: Dis na blɔd tɛst bak. I de mכsu di כmכnt כf fεt mכlikul dεm we dεn kכl lipid dεm na yu bכdi. Dis tɛst kin gɛt 4 kɔlɔstrel mɛzhɔmɛnt ɛn wan triglisrayd mɛzhɔmɛnt. Bɔrku tɛm, lipodystrophy kin mek di kɔlɔstrel lɛvɛl nɔr nɔr fayn.
• Lɛptin Tɛst: Dis de mɛzhɔ di lɛvɛl we lɛptin de na yu blɔd. If yu gɛt lipodystrophy ɛn yu lɛptin lɛvɛl smɔl pas aw i nɔmal, dis kin gi yu sɔm aidia bɔt aw yu bɔdi go ansa to lɛptin riplesmɛnt tɛrapi.
• Jɛnɛtik Tɛst: If yu dɔktɔ sɔprayz se yu gɛt wan kayn Lipodystrophy we yu gɛt frɔm yu mama ɛn papa, dɛn kin se yu fɔ du jenɛtik tɛst fɔ kɔnfirm di sik.
• Kidni bayɔpsi:Dis involv fɔ ɔpreshɔn fɔ pul wan sampul pan di kidni tisu ɛn chɛk am ɔnda maykroskɔp. Yu dɔktɔ kin ɔda dis tɛst fɔ si if yu kidni dɛn dɔn afɛkt wit lipodystrophy.

Wetin na di tritmɛnt dɛm fɔ lipodystrophy?

Di tritmɛnt ɛn manejmɛnt fɔ lipodystrophy de dipen pan di patikyula kayn we yu gɛt, ɛn if yu gɛt ɔda tin dɛn we gɛt fɔ du wit am, lɛk dayabitis ɔ di kɔlɔstrel lɛvɛl we nɔmal.

di mεnejmεnt tritmεnt dεm we dεn kin yus fכ lipodystrophy na:

• Mεdikeshכn fכ riples lεptin: Yu dכkta kin gi yu wan sεntetik fכm fכ di כmon lεptin we dεn kכ l mεtreleptin . Bɔku tɛm, pipul dɛn we gɛt lipodystrophy nɔ kin gɛt bɛtɛ lɛptin. dis כmon de εp fכ rεgεl di bכdi in mεtabolism εn i kin ridyus di hכy kכlestכl εn triglisεrayd lεvεl dεm bak.
• Tritmɛnt fɔ dayabitis ɛn insulin rɛsistɛns: If yu gɛt insulin rɛsistɛns ɛn/ɔ dayabitis bikɔs ɔf lipodystrophy, yu dɔktɔ kin gi yu mɛrɛsin dɛn we yu kin it lɛk pioglitazone, metformin, sulfonylureas , ɔ thiazolidinediones fɔ trit am. Sɔm pipul dɛm wae gɛt lipodystrophy kin nid bak fɔ tek sintetik insulin fɔ trit dɛn dayabitis. Yu kin nid bak fɔ chɛk yu blɔd shuga ɔltɛm na os wit glukomita .
• Fɔ kɔntrol di triglisrayd ɛn kɔlɔstrel lɛvɛl: Di mɛrɛsin dɛn we dɛn kin tek bay mɔt we wi bin dɔn tɔk bɔt we kin ɛp fɔ trit dayabitis kin ɛp fɔ kɔntrol di kɔlɔstrel lɛvɛl bɔku tɛm. Yu dɔktɔ kin gi yu bak statin dɛn lɛk rosuvastatin ɛn pravastatin . Pipul dεm we gεt hכy triglisεrayd lεvεl kin nid fכ tek supliment fכ fibrik asid dεrivεt כ n-3 polyunsaturated fεt asid , lεk dεn wan dεm we de insay fish כyl.
• Kɔsmɛtik ɔpreshɔn ɛn di we aw dɛn kin du am: Pipul dɛn we gɛt lipodystrophy na di say dɛn we dɛn kin kɔsmɛtik, lɛk di fes, chɛst, ɛn di say dɛn we dɛn kin gɛt bɔdi, kin gɛt kɔsmɛtik ɔpreshɔn fɔ mek dɛn luk fayn ɛn fɔ mek dɛn gɛt kɔnfidɛns pan dɛnsɛf. Plastik sajin kin du autologous adipose tissue transplantation, fes rikostrɔkshɔn yuz fri flap, ɛn silikon ɔ ɔda implant. dεn kin yuz liposuksh כn כ כspitul tεknik dεm bak fכ pul di fεt we dεn nכ want na di εria dεm lεk di chin כ bak pan di nεk (dεn kin kכl am "bכfalo hכmp" ).

Sayɛnsman dɛn stil gɛt bɔku tin fɔ lan bɔt aw fɔ trit ɛn mɛn lipodystrophy. As dεn de diskova mכr bכt di kכmplisiti dεm fכ mεtabolik prכsεs, mכr tritmεnt opshכn dεm kin kam.

Yu tink se dɛn kin mek dɛn nɔ gɛt lipodystrophy?

Bɔrku tɛm, dɛn nɔ kin ebul fɔ stɔp Lipodystrophy.

di jεnεtik fכm dεm fכ lipodystrophy nכ kin bכku, biכs na di rizulεt fכ wan inhεrit jin mכtεshכn. If yu de plan fɔ bɔn pikin, ɔndastand di prɔblɛm we kin apin we yu bɔn pikin we gɛt wan sik ɛn tɔk to yu dɔktɔ bɔt aw fɔ tɛst yu jɛnɛtiks.

Bɔku tɛm, di lipodystrophy we pɔsin kin gɛt kin kam bikɔs ɔf infεkshɔn ɔ sik we de mek di imyun sistɛm sik. Pan ɔl we sɔm infɛkshɔn, lɛk chikinpoks ɛn kɔf, dɛn kin ebul fɔ avɔyd bay we dɛn gi yu vaysin, ɔda infɛkshɔn ɛn imyun sistɛm sik dɛn we gɛt fɔ du wit akwyayz lipodystrophy nɔ kin ebul fɔ avɔyd.

Wetin na di prɔgnosis fɔ lipodystrophy?

Di luk fɔ lipodystrophy de dipen mɔ pan us kayn lipodystrophy yu gɛt, ɛn if yu gɛt ɔda kɔndishɔn ɔ kɔmplikeshɔn dɛn we gɛt fɔ du wit am, lɛk dayabitis, liva ɔ kidni prɔblɛm.

Kɔsmɛtik kɔrɛkshɔn fɔ di say dɛn we gɛt smɔl fat ɛn di say dɛn we gɛt bɔku fat kin ɛp fɔ mek di kwaliti fɔ layf fɔ pipul dɛn we gɛt lipodystrophy bɛtɛ.

If dɛn no se yu ɔ yu pikin gɛt lipodystrophy, tɔk to yu dɔktɔ bɔt wetin fɔ ɛkspɛkt ɛn aw fɔ mɛn di sik fayn fayn wan.

Ustɛm yu fɔ go to dɔktɔ bɔt lipodystrophy?

If yu notis se yu ɔ yu pikin in bɔdi fat de kɔntinyu fɔ go dɔŋ na sɔm patikyula say dɛn, ɔ se di fat de go ɔp na sɔm say dɛn, tɔk to yu dɔktɔ.

If yu ɔ yu pikin gɛt Lipodystrophy, yu fɔ mit wit yu mɛdikal tim ɔltɛm fɔ mek shɔ se yu tritmɛnt de wok fayn fɔ yu.

Fɔ dɔn, tin dɛn we wi fɔ mɛmba

Lipodystrophy na wan sik wae nɔr kin bɔrku bɔt wae kin siriɔs. Pan ɔl we no mɛrɛsin nɔ de, sɔm tritmɛnt dɛn kin ɛp fɔ kɔntrol di sik dɛn we i gɛt ɛn di tin dɛn we gɛt fɔ du wit am, lɛk dayabitis ɛn di kɔlɔstrel we nɔ de wok fayn.

Di tritmɛnt we dɛn kin gi kin difrɛn frɔm wan pɔsin to ɔda pɔsin. So, yu mɛdikal tim go wok wit yu fɔ mek wan plan we go fayn fɔ yu. Nɔ fred fɔ aks yu dɔktɔ kwɛstyɔn dɛn. Dɛn de de fɔ ɛp yu. Dis no we yu no go mɔs ɛp yu fɔ liv fayn layf!

` lipodystrophy, adipos tisu, lεptin, jεnεtik, akwyayz, dayabεtis, kכlestכl, triglisεrayd, HIV, mεtabolik sik dεm