Kɔnstipɛshɔn bikɔs ɔf opioid? Na dis na wan sɔlv: Lan bɔt di methylnaltrexone injɛkshɔn!

Sɔntɛnde, we wi tek strɔng pen kil, ɔ opioid, we dɔktɔ dɛn gi wi fɔ siriɔs prɔblɛm, afta dɛn dɔn ɔpreshɔn wi, ɔ fɔ pen we de kɔntinyu, wi kin dɔn wit difrɛn prɔblɛm, nɔto so? Dat na kɔnstipɛshɔn . Fɔ sɔm pipul dɛn, dis kin mek dɛn vɛks so dat dɛn nɔ kin ivin ebul fɔ it ɔ drink. So tide wi go tɔk bɔt wan spɛshal injɛkshɔn we de ɛp wit kɔnstipɛshɔn we opioid kin mek. Dat na wan drɔg we dɛn kɔl methylnaltrexone.

Wetin na dis mɛrɛsin we dɛn kɔl methylnaltrexone? Aw i kin wok?

Naw lɛ wi tek wan luk pan wetin na dis mɛrɛsin we dɛn kɔl methylnaltrexone ɛn aw i kin ɛp yu. Fɔ tɔk am simpul wan, dɛn mek am spɛshal fɔ trit kɔnstipɛshɔn we de kam bikɔs ɔf di opioid dɛn we yu de tek fɔ pen.

Tink bɔt am, de opioid wae yu de tek kin rili ridyus pen. Na tru dat. Bɔt dɛn kin slo yu bɔdi muvmɛnt bak, we kin mek yu insay dɛn ‘lɛs’ smɔl. Di spid we di stɔl de muv tru yu insay de slo. Na da tɛm de di bɔdi kin delay, sɔntɛnde i kin las fɔ sɔm dez, ɔ i kin rili at.

So, dis methylnaltrexone drɔg de du wan rili wɔndaful tin. I de blok di ifekt dεm we dεn opioid dεm de gi na yu gכt, we na fכ stכp di bכdi fכ wok. Bɔt, di tin we impɔtant pas ɔl na dat, i nɔ de go na yu bren fɔ mek yu nɔ fil pen. I jɔs de wok dairekt pan yu insay. Dɔn di mɔsul dɛn na yu insay kin bigin fɔ wok fayn bak, ɛn dis kin ɛp yu fɔ pas stɔl. Bɔku tɛm, yu kin si di tin dɛn we kin apin insay af awa. Wi kin kɔl dis kayn drɔg ‘opioid blɔk’ . Dat min se i de blok sɔm pan di akshɔn dɛm we opioid de du, mɔ di ifɛkt we dɛn gɛt pan di intestinal dɛm.

Sɔntɛnde, dɔktɔ kin gi yu dis mɛrɛsin fɔ ɔda sik, so if yu gɛt ɛni kwɛstyɔn, aks yu dɔktɔ ɔ di fama. Dis mɛrɛsin de kam bak ɔnda di brand nem `(Relistor)`.

Wetin na de tin wae yu nid fɔ tɛl yu dɔktɔ bifo yu tek dis mɛrɛsin?

Bifo yu bigin fɔ tek methylnaltrexone, i impɔtant fɔ gi yu dɔktɔ kɔmplit diskripshɔn bɔt yu wɛlbɔdi kɔndishɔn. Dis na bikɔs na da tɛm de nɔmɔ yu go ebul fɔ no if dis mɛrɛsin fayn fɔ yu. Na sɔm tin dɛn we yu fɔ rili no:

• If yu gɛt sik na yu kidni . Bikɔs bɔku mɛrɛsin dɛn kin kɔmɔt na di bɔdi tru di kidni, if yu gɛt prɔblɛm wit yu kidni, yu nid fɔ tink gud wan bɔt di doz fɔ di mɛrɛsin.
• If yu gɛt liva sik . Di liva na wan men ɔgan bak we de klin wi bɔdi frɔm drɔgs. So if liva prɔblɛm de, wi fɔ tɔk bɔt dat bak.
• Sɔntin we nɔ fayn wit yu bɛlɛ ɔ yu insay?If i de. Fɔ ɛgzampul, if di intestinal blɔk, ɔlsa, ɔ ɔda siriɔs tin. Bikɔs dis mɛrɛsin de mek di intestinal dɛn wok mɔ, i nɔ kin fayn fɔ pipul dɛn we gɛt dɛn kayn sik ya.
• If yu dɔn gɛt alɛji fɔ methylnaltrexone, ɛni ɔda mɛrɛsin, it, day, ɔ tin dɛn we de mek yu nɔ pwɛl.
• If yu gɛt bɛlɛ ɔ yu de tray fɔ gɛt bɛlɛ, i impɔtant fɔ tɔk to yu dɔktɔ bifo yu tek ɛni mɛrɛsin dis tɛm.
• If yu na mama we de gi pikin in mama in bɛlɛ, yu fɔ no bak se sɔm mɛrɛsin kin pas to yu pikin tru in mama in milk.

Nɔto dɛn tin ya nɔmɔ, bɔt i rili impɔtant bak fɔ tɛl yu dɔktɔ bɔt ɛni wɛlbɔdi prɔblɛm we yu gɛt ɛn ɛni ɔda mɛrɛsin we yu de tek.

Aw a go yuz dis mɛrɛsin? Wetin na di bɛst we?

Dɛn kin gi dis mɛrɛsin we dɛn kɔl methylnaltrexone as injɛkshɔn ɔnda di skin . Dɛn kin gi am na ɔspitul ɔ klinik.

Bɔt sɔntɛnde yu kin gɛt fɔ gi yusɛf dis injɛkshɔn na os. If dat apin, nɔ wɔri. Yu dɔktɔ ɔ nɔs go tich yu jɔs aw fɔ pripia am, aw fɔ injɛkt am ɔnda yu skin, ɛn aw fɔ du am klin wan. Yu fɔ du am jɔs lɛk aw dɛn tɛl yu, insay di sem ɔda. I nɔ fayn fɔ tek am mɔ ɔ mɔ pas aw di dɔktɔ tɛl yu.

Di tin we impɔtant pas ɔl na dat, yu nɔ fɔ put yu nidul ɛn sirinj dɛn we yu dɔn yuz na di dɔti? Wan spɛshal shap kɔntena de fɔ dat. Yu kin aks fɔ am na yu famasi ɔ dɔktɔ. Na de yu fɔ put dɛn tin ya we yu dɔn yuz. Dis na fɔ mek wi ɔl sef ɛn fɔ mek wi nɔ put ɔda pipul dɛn pan denja.

We dɛn gi yu dis mɛrɛsin, di famasi go gi yu wan spɛshal infɔmeshɔn liflet we dɛn kɔl ``MedGuide'' . Dɛn kin gi yu dis ɛvri tɛm we yu gɛt nyu mɛrɛsin, ivin we yu gɛt rifil. I gɛt bɔku impɔtant tin dɛn bɔt di mɛrɛsin. So, i rili impɔtant fɔ tek tɛm rid am.

Dɛn fɔ tek tɛm spɛshal we dɛn de gi pikin dɛn dis mɛrɛsin . So if yu want fɔ gi yu pikin dis mɛrɛsin, tek tɛm tɔk to yu dɔktɔ bɔt am ɛn fala wetin dɛn tɛl yu fɔ du.

Wetin fɔ du if yu tek bɔku mɛrɛsin? (Ovadosage) .

If yu tink se yu dɔn tek dis mɛrɛsin tumɔs, kɔl pɔyzin kɔntrol sɛnta ɔ imejensi rum we de nia yu wantɛm wantɛm. If nɔto dat, go wantɛm wantɛm.

Mɛmba se dis mɛrɛsin na fɔ yu nɔmɔ. Nɔ ɛva sheb dis mɛrɛsin wit ɔda pipul dɛn.

Wetin a go du if a mis wan doz?

Dis nɔto mɛrɛsin we dɛn kin tek di sem tɛm ɛvride. Dat min se, i nɔto mɛrɛsin we dɛn kin yuz ɔltɛm. Dɛn kin gi am as nid de. So, nid nɔ de fɔ wɔri bɔt fɔ mis apɔntinmɛnt fɔ tek mɛrɛsin. Bɔt if yu gɛt ɛni kwɛstyɔn bɔt aw yu dɔktɔ tɛl yu fɔ yuz am, aks am.

Us ɔda tin dɛn kin miks wit dis mɛrɛsin? (Intarakshɔn dɛn)

Sɔm mɛrɛsin dɛn de we kin mek yu gɛt prɔblɛm if yu tek am wit methylnaltrexone. Fɔ ɛgzampul:

• Alvimopan we de na di wɔl
• Nalɔkson we dɛn kɔl
• Naltrekson we gɛt di sik

Dis list nɔ kɔmplit. Sɔntɛm ɔda mɛrɛsin dɛn de. So, tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek (ilɛksɛf ɔda dɔktɔ dɛn gi yu ɔ yu bay am na di famasi), ɛbul prɔdak, vaytamɛn, ɛn it we yu de yuz. Dɔn bak, mek shɔ se yu tɛl yu dɔktɔ if yu de smok, drink rɔm, ɔ yuz ɔda drɔgs we nɔ rayt. Sɔm tin kin miks wit dis mɛrɛsin ɛn mek prɔblɛm.

Wetin wi fɔ tek tɛm mɔ we wi de tek dis mɛrɛsin?

Sɔm tin dɛn de we yu fɔ tek tɛm wit we yu de yuz dis mɛrɛsin:

• Afta yu dɔn tek dis injɛkshɔn, de na say we yu go ebul fɔ go na tɔylɛt kwik kwik wan. Yu kin nid fɔ defecate jɔs afta yu dɔn tek dis mɛrɛsin. Sɔntɛnde, i kin apin wantɛm wantɛm.
• We yu de tek dis mɛrɛsin, yu mɛdikal tim go wach yu sik gud gud wan. If yu sik nɔr de bɛtɛ, ɔr if dɛn de wɔs, tɛl yu dɔktɔ ɔr nɔs wantɛm wantɛm.
• Yu kin fil smɔl smɔl ɔ yu kin gɛt diziz afta yu dɔn tek dis mɛrɛsin. So, te yu no gud gud wan aw dis mɛrɛsin de afɛkt yu, nɔ drayv, yuz mashin, ɔ du ɛnitin we nid fɔ pe atɛnshɔn.
• Nɔ tinap ɔ sidɔm wantɛm wantɛm. Tek tɛm mɔ if yu dɔn ol. We yu du dat, i kin mek yu ed de tɔn ɛn yu kin fɔdɔm.
• Nɔ drink rɔm. Rɔm kin ambɔg di wok we dis mɛrɛsin de du.

Wetin na di sayd ɛfɛkt dɛm we dis mɛrɛsin kin gɛt? (Sayd Ɛfɛkt dɛn)

Lɛk ɛni mɛrɛsin, methylnaltrexone kin mek sɔm sayd ɛfɛkt dɛn. Bɔt, nɔto ɔlman kin gɛt dɛn. Sɔm kin siriɔs, ɛn sɔm nɔ kin rili siriɔs.

Di sayd ɛfɛkt dɛm we yu fɔ ripɔt to yu dɔktɔ wantɛm wantɛm:

If yu gɛt ɛni wan pan dɛn sik ya, tɛl yu wɛlbɔdi tim kwik kwik wan:

• Di tin dɛn we kin mek pɔsin gɛt alɛji:Skin rash, it, simptom dɛm we tan lɛk rash, swel na yu fes, lip, tɔng, ɛn trot. Dɛn tin ya kin rili denja.
• Bɛlɛ pen bad bad wan: Dis min se di pen kin tranga, i kin kɔntinyu fɔ de, ɛn i kin go ɔp pas di nɔmal bɛlɛ pen.

Sayd ɛfɛkt dɛm wae nɔr kin nid dɔktɔ advays, bɔt yu fɔ ripɔt to yu dɔktɔ if dɛn kɔntinyu ɔr de mɔna yu:

Bɔku tɛm, dɛn tin ya kin go insay sɔm dez. Bɔt if dɛn kɔntinyu fɔ de ɛn mɔna yu, tɛl yu dɔktɔ se:

• Fɔ fil kol (Chills) .
• Rɔnbɛlɛ
• We pɔsin de swet pasmak
• Ed de at
• Vɔmit
• Bɛlɛ pen (nɔto spɛshal) .

Dis list nɔ de inklud ɔl di sayd ɛfɛkt dɛn we pɔsin kin gɛt. If yu notis ɛni ɔda tin we nɔ de na di list, tɔk to yu dɔktɔ bɔt am. Yu kin ripɔt di sayd ɛfɛkt to di FDA na 1-800-FDA-1088.

Aw fɔ kip dis mɛrɛsin? (Usay fɔ kip)

I rili impɔtant bak fɔ kip di mɛrɛsin dɛn fayn fayn wan.

• Kip dis mɛrɛsin usay pikin ɛn animal dɛn we yu lɛk nɔ go ebul fɔ rich.
• Stɔr am na rum tɛmpracha (bitwin 20 ɛn 25 digri sɛlshiɔs, bitwin 68 ɛn 77 digri F) . Nɔ kip am na say we kol pasmak (lɛk na friza). Dɔn bak, protɛkt frɔm layt.
• Nɔ yuz mɛrɛsin dɛn we dɔn pas. Trowe dɛn fayn fayn wan.

Dis liflet na jɔs sɔmari. Sɔntɛm i nɔ go gɛt ɔl di tin dɛn we yu nid. If yu gɛt ɛni ɔda kwɛstyɔn bɔt dis mɛrɛsin, duya tɔk to yu dɔktɔ, fama, ɔ ɔda pɔsin we de kia fɔ yu wɛlbɔdi biznɛs.

Di tin dɛn we impɔtant pas ɔl fɔ mɛmba (Take-Home Message) .

Okay, so, wi go mɛmba yu bak di impɔtant tin dɛn we yu nid fɔ mɛmba frɔm wetin wi dɔn tɔk bɔt?

1. Methylnaltrexone na spεshal injεkshכn we dεn kin gi fכ kכnstεpshכn we opioid (pen kil dεm) kin mek.

2. Dis de wok pan di intestines nɔmɔ, i nɔ gɛt ɛni ifɛkt pan pen kil.

3. Mek shɔ se yu tɛl yu dɔktɔ bɔt ɛni ɔda sik we yu gɛt ɛn ɛni mɛrɛsin we yu de tek.

4. Yuz di injɛkshɔn jɔs lɛk aw yu dɔktɔ tɛl yu. Trowe di nidul dɛn we yu dɔn yuz fayn fayn wan.

5. Stay nia tɔylɛt afta yu dɔn tek di injɛkshɔn. Yu fɔ no se yu de slip ɛn yu ed de tɔn, bikɔs dis kin apin.

6. If yu gɛt bad bad bɛlɛ pen ɔ yu gɛt alɛji, tɛl yu dɔktɔ wantɛm wantɛm.

A op se yu si dis infɔmeshɔn yusful. Stay wit wɛlbɔdi!

` Methylnaltrexone, Methylnaltrexone, opioid kɔnstipɛshɔn, kɔnstipɛshɔn mɛrɛsin, Relistor, drɔg sayd ifɛkt, injɛkshɔn