Yu liva na wan wɔndaful ɔgan. I de mek wan wata we dɛn kɔl ‘bile’ we de ɛp wi fɔ dayjɛst di fat it dɛn we wi de it. Bɔt pan pɔsin we gɛt wan sik we dɛn kɔl Primary Biliary Cholangitis (PBC), di dilik dakt dɛn we de kɛr dis bayl kin pwɛl. dis kin mek di bayl nכ de fכlכ fayn fayn wan εn i kin blכk insay di liva. As tɛm de go, dis bayl we dɔn blok kin at fɔ tɔn to ston ɛn mek pɔsin gɛt infɛkshɔn. Afta sɔm tɛm, dis bayl de bak ɛn mek skata insay di liva. Dis na di besik nature of PBC.
Bɔt nɔ wɔri. Gud mɛrɛsin dɛn de we kin ɛp fɔ pul di bayl na di liva ɛn ridyus di fɔmɛshɔn fɔ dɛn skata ya. Bɔt if yu nɔ trit PBC fayn, ɔ if di sik kam tranga smɔl, sɔm prɔblɛm dɛn kin apin. Tide, wi go tɔk bɔt di prɔblɛm dɛn we kin apin to PBC ɛn aw fɔ manej dɛn.
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Sirosis, na wan siriɔs sik
Sirosis na we di hεlty sεl dεm na yu liva de riples wit ska tisu. Fɔ tɔk am simpul wan, di liva kin at smɔl smɔl ɛn tɔn to ston. dis kכndyushכn de apin na di las stej dεm na di PBC. Bay dis tɛm, di liva dɔn ɔlrɛdi pwɛl bad bad wan.
Sirosis na siriɔs sik wae wi nid fɔ no bɔt, bikɔs i kin mek wi gɛt siriɔs sik lɛk wae yu liva nɔr de woke fayn ɛn yu kin gɛt kansa na yu liva.
Trade, dɛn bin de kɔl PBC ‘primary biliary cirrhosis’. Dis na bikɔs ɔf aw di kɔmplikeshɔn fɔ sirosis gɛt fɔ du wit dis sik.
Aw dɛn kin trit dis?
Yu dɔktɔ go gi yu mɛrɛsin fɔ kɔntrol dis sik.
- Bɔku tɛm, di fɔs tritmɛnt na wan mɛrɛsin we dɛn kɔl ursodeoxycholic acid (Ursdiol) . dis de wok bay we i de pul di bayl na di liva εn i de ridyus di damej we di liva de du.
- If yu nɔr fil bɛtɛ wit dis mɛrɛsin nɔmɔ, yu dɔktɔ kin se yu fɔ tek wan mɛrɛsin we dɛn kɔl obeticholic acid (Ocaliva) apat frɔm am.
- Apat frɔm dat, dɛn dɔn gri naw fɔ yuz nyu mɛrɛsin dɛn lɛk elafibranor (Iqirvo) ɛn seladelpar (Livdelzi) wit ursodeoxycholic acid.
- Wan ɔda tin we yu kin du na wan klas we dɛn kɔl fibrates . Pan ɔl we dɛn rili gri fɔ mek dɛn blɔd fat (lipid) smɔl, dɛn dɔn si se dɛn de wok fayn fayn wan pan PBC pasɛnt dɛn we nɔ de ansa fayn to ursodeoxycholic acid. Dis we ya, we dɔktɔ yuz mɛrɛsin fɔ ɔda kɔndishɔn pas di wan we dɛn bin gri fɔ, wi kin kɔl am ‘ɔf-lɛbul’ yus.
Bɔt ilɛk us tritmɛnt yu yuz, if di ska tisu na di liva tumɔs ɛn di liva nɔ ebul fɔ wok, di wangren tin we yu go du na fɔ transplant di liva.Nɔmɔ. Wetin yu de du de na fɔ pul yu liva we dɔn pwɛl ɛn transplant am wit liva frɔm pɔsin we gɛt wɛlbɔdi.
di prεshכn we de go כp na wan vein na di liva (Portal Hypertension) .
Dis na ɔda siriɔs prɔblɛm. Lɛ wi ɔndastand dis. Wi gɛt wan men blɔd vesel we de briŋ blɔd to wi liva. dis na wetin wi kכl di 'pכtal vein'.
naw, we di ska tisu de fכm insay di liva bikoz fכ di kכndishכn fכ sirosis we wi bin tכk bכt, di fכ fכlכ bכdi tru dis ‘pכtal vein’ de bכku. Jɔs lɛk aw trafik jam na rod, di blɔd nɔ kin ebul fɔ flɔ fayn ɛn i kin stɔp insay da vein de. As di blɔd de gɛda lɛk dis, di prɛshɔn we de insay da vein de de go ɔp smɔl smɔl. Dɔktɔ dɛn kɔl dis kɔndishɔn pɔtal haypatɛnshɔn .
Wetin mek dis denja? Dis ay prɛshɔn kin mek di dilik blɔd vesel dɛn we de insay di bɔdi bɔs, ɛn mek blɔd kɔmɔt insay di bɔdi . So, e fayn fɔ trit dis kwik kwik wan.
Lɛ wi jɔs ɔndastand dɛn tu kɔmplikeshɔn ya frɔm di tebul we de dɔŋ ya.
| Kɔmplikɛshɔn | Fɔ tɔk am simpul wan... | Men Risk |
|---|---|---|
| Sirosis sik | fכmeshכn fכ ska tisu insted fכ hεlty liva tisu (liva stכn dεm). | Liva Failure ɛn Liva Kansa. |
| Pɔtal Haypatɛyshɔn | Sirosis kin mek di vein dɛm we de briŋ blɔd na di liva blok, ɛn dis kin mek di prɛshɔn we de de go ɔp. | Blɔd we de kɔmɔt insay pɔsin in bɔdi. |
Wetin na di tritmɛnt dɛm fɔ dis?
Yu dɔktɔ kin gi yu mɛrɛsin lɛk beta-blɔka fɔ ridyus di prɛshɔn we de na dis ‘pɔtal vein.’ Dɛn tin ya kin kɔntrol yu blɔd prɛshɔn fɔ sɔm tɛm.
Bɔt mɛmba se di wangren ɛn pɔrmɛnt tritmɛnt we kin stɔp pɔtal haypatɛyshɔn kpatakpata na fɔ transplant liva.Nɔmɔ. Bikɔs di men tin we kin mek dis apin na di damej we di liva kin gɛt we sik we dɛn kɔl sirosis kin kam wit. Bikɔs dɛn nɔ go ebul fɔ mek da damej de, di las tin we dɛn fɔ du na fɔ pul di liva we dɔn pwɛl ɛn put nyu wan insay.
PBC na sik wae yu kin kɔntrol fayn fayn wan if yu gi yu fayn mɛrɛsin ɛn advays. So, if yu gɛt dis sik, nɔ panik, de tɔk to yu dɔktɔ ɔltɛm, ɛn fala di tritmɛnt we dɛn tɛl yu fɔ du di rayt tin. Dat na di bɛst we fɔ mek yu nɔ gɛt dɛn kayn prɔblɛm dɛn ya.
Mɛsej we dɛn kin kɛr go na os
- Praymari Biliary Cholangitis (PBC) na sik we de pwɛl di dilik dakt dɛm na di liva we de kɛr bayl.
- If dɛn nɔ trit dis sik fayn, siriɔs prɔblɛm dɛn lɛk sirosis ɛn pɔtal haypatɛnshɔn kin apin.
- Sirosis na wan sik wae de mek di ska tisu kin kam pan di liva, we kin mek di liva nɔ wok fayn ɛn ivin gɛt kansa.
- Pɔtal haypatɛnshɔn na we di prɛshɔn de go ɔp na di vein we de kɛr blɔd go na di liva. Dis kin mek blɔd kɔmɔt insay di bɔdi.
- If yu gɛt PBC, tɔk to yu dɔktɔ ɔltɛm bɔt ɛnitin we yu de wɔri bɔt . I rili impɔtant fɔ tek yu mɛrɛsin dɛn jɔs lɛk aw dɛn tɛl yu fɔ tek ɛn fala wetin yu dɔktɔ tɛl yu fɔ du.
- Bɔku tɛm, di las sɔlv kin bi fɔ transplant liva.
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