Bɔku tɛm yu kin fil taya ɛn yu kin taya? Yu kin si am se i nɔ kin izi fɔ yu fɔ blo we yu de waka fast smɔl ɔ we yu de klaym stej? Sɔntɛm yu kin fil bak se yu skin dɔn pal pas aw yu kin fil. Dɛn tin ya kin bi sayn fɔ se blɔd nɔ de na di bɔdi, we na wetin wi kin kɔl anemia pan mɛrɛsin. Bɔt sɔntɛnde, di tin we kin mek pɔsin gɛt dis anemia kin bi wan sik we kɔmpleks ɛn we nɔ kin bɔku pas aw wi kin tink. Tide wi go tɔk bɔt wan pan dɛn kayn sik ya we nɔ bɔku, bɔt we rili impɔtant we gɛt fɔ du wit blɔd. Dat na Pure Red Cell Aplasia, we wi kɔl PRCA fɔ shɔt.
Fɔ tɔk am simpul wan, wetin na dis PRCA?
Tink bɔt di bon mɛro we de na wi bɔdi as faktri we de mek blɔd. Dis faktri de mek di tri kayn sɛl dɛn we wi bɔdi nid: rɛd blɔd sɛl, wayt blɔd sɛl, ɛn pletlɛt. Di men wok we rɛd blɔd sɛl dɛn de du na fɔ kɛr di ɔksijɛn we de kam insay wi lɔng we wi de blo to ɔl di ɔda sɛl dɛn na wi bɔdi. I tan lɛk trak savis we de gi ɔksijɛn.
Naw, we i kam pan PRCA, di faktri we de mek blɔd, dat na di bon mɛro, kin ridyus ɔ stɔp fɔ mek rɛd blɔd sɛl nɔmɔ . di prodakshכn fכ כda tכp sεl dεm (wayt bכdi sεl dεm εn pletlet dεm) de apin nכmal wan. So we di nɔmba fɔ di rɛd blɔd sɛl dɛn we de kɛr ɔksijɛn go na di bɔdi de go dɔŋ, di ɔgan dɛn na wi bɔdi nɔ de gɛt di ɔksijɛn we dɛn nid. Di siriɔs anemia we kin kɔmɔt frɔm dis na di men prɔblɛm fɔ PRCA.
Us sayn dɛm wae pɔrsin wae gɛt PRCA kin gɛt?
PRCA kin mek yu gɛt di sem sayn dɛn we pɔsin kin gɛt we i nɔ gɛt bɛtɛ blɔd, bɔt dɛn kin rili bad pas di nɔmal anemia. I impɔtant fɔ mek yu no bɔt dɛn sik ya.
| Di sayn we de sho se di sik de | Wan simpul ɛksplen |
|---|---|
| Taya | Fɔ fil se yu nɔ gɛt layf ɛn yu taya ɔltɛm, ilɛksɛf yu slip bɔku. |
| I nɔ izi fɔ blo (Dyspnea) . | Fɔ fil se yu nɔ de blo fayn ivin afta yu dɔn du smɔl wok ɔ yu dɔn waka fɔ shɔt tɛm. |
| Diziz we pɔsin kin gɛt | Fɔ fil diziz, mɔ we yu grap frɔm we yu sidɔm. |
| Pale skin | Di skin, di lip, ɛn ɔnda di nel dɛn kin wayt pas aw i kin wayt. |
| Yu ed kin at ɔltɛm | Di ed we kin at bɔku tɛm kin kam bikɔs di ɔksijɛn we di bren nid nɔ de bɔku. |
| Fɔ yɛri wan ring na yu yes (Pulsatile tinnitus) . | Dɛn kin yɛri wan sawnd we de mek pɔsin wispa na di yes dɛn akɔdin to di ritm we di at de bit. |
| Chɛst pen (Angina) . | chɛst de pen bikɔs ɔf di ɔksijɛn we nɔ de na di at mɔsul dɛm. |
De tin wae impɔtant pas ɔl na, if yu gɛt wan ɔr mɔr pan dɛn sik ya, nɔr panik ɛn tink se na PRCA. Dɛn kin si dɛn tin ya bak pan nɔmal anemia. Bɔt if dɛn sik ya kɔntinyu, i go mɔs bi se yu go to dɔktɔ ɛn gɛt advays.
Wetin mek dis tin we dɛn kɔl PRCA kin apin?
PRCA nɔto wan sik. Bɔku tin dɛn de we kin mek i apin. Sɔntɛnde, i kin bi bak wan sayd ɛfɛkt fɔ ɔda mɛrɛsin.
1. Prɔblɛm dɛn we de na di imyun sistɛm (Autoimmune Diseases) .
Dis na di men tin we de mek PRCA de. Fɔ tɔk am simpul wan, di difɛns sistɛm we wi bɔdi de fɛt, we na di imyun sistɛm, kin mistek bigin fɔ atak di stem sɛl dɛn we de na wi yon bon mɛro we de mek rɛd blɔd sɛl dɛn. Sɔm ɛgzampul dɛn bɔt dɛn kayn tin ya na:
- Lupus sik (Systemik Lupus Ɛritɛmatosɔs) .
- Rimatɔyd Atraytis
- Inflammatory Bowel Disease we pɔsin kin gɛt
2. Kansa
Sɔm kayn kansa kin mek bak PRCA.
- Kansa wae gɛt fɔ du wit blɔd: Chronic Lymphocytic Leukemia (CLL) ɛn Large Granular Lymphocytic Leukemia (LGL) na di tu kayn blɔd kansa dɛm wae kin gɛt fɔ du wit dis.
- Tumɔs: Taymoma, we na kansa na di taymus gland, na di men kansa tɔŋ we gɛt fɔ du wit PRCA.
3. Vayral ɛn baktriyal infɛkshɔn
Sɔm sik dɛn we kin gɛt dis sik kin mek bak PRCA, fɔ sɔm tɛm ɔ fɔ ɔltɛm.
- Vayrɔs: Parvovirus B19 na di wan we pipul dɛn sabi pas ɔl pan dɛn. dis vayrus de atak di sεl dεm na di bon mכro dεm we de kam bi rεd bכdi sεl dεm dεn wan dεm. HIV, Epstein-Barr vayrɔs, ɛn epataytis vayrɔs kin mek am bak.
- Baktri: Kɔndishɔn lɛk Grup C Streptococcus, Tuberculosis, ɛn Bacterial Sepsis kin mek dis bak.
4. Sɔm mɛrɛsin dɛn
PRCA kin apin bak as sayd ɛfɛkt fɔ sɔm mɛrɛsin dɛn. Fɔ ɛgzampul, Erythrocyte-Stimulating Agents (ESAs), we na drɔgs we dɛn kin gi to pipul dɛn we gɛt kidni fɔ mek dɛn gɛt mɔ rɛd blɔd sɛl, kin mek dɛn gɛt dis sik sɔntɛnde.
5. We pɔsin gɛt bɛlɛ
Na smɔl tɛm nɔmɔ, sɔm uman dɛn kin gɛt PRCA we dɛn gɛt bɛlɛ. Laki, di sik kin sכlv insεf afta dεn bכn di pikin.
6. Jεnεtik kכndishכn dεm we de we dεn bכn am
Diamond-Blackfan Anemia na wan sik we dɛn kin bɔn we dɛn bɔn wit blɔd we nɔ kin apin so ɔltɛm. Bɔku tɛm, dɛn kin no am we dɛn smɔl. Dɛn sik pipul ya kin gɛt PRCA bak.
Aw dɔktɔ dɛn kin no dis sik kɔrɛkt wan?
We yu go to dɔktɔ wit di sayn dɛn we wi bin dɔn tɔk bɔt, i go chɛk yu ɛn if i tink se dis sik de, i go sɛn yu fɔ mek dɛn du sɔm tɛst dɛn.
| Tɛst | Wetin yu de si na ya? |
|---|---|
| Kɔmplit Blɔd Kɔnt (CBC) . | Dɛn kin chɛk di blɔd fɔ si if di rɛd blɔd sɛl dɛn rili smɔl, ɛn if di wayt blɔd sɛl ɛn pletlɛt dɛn nɔmal. |
| Rɛtikulosayt Kɔnt | Dis de tɔk bɔt nyu rɛd blɔd sɛl dɛn we dɔn mek ɛn we nɔ machɔ. Insay PRCA, dis nɔmba rili smɔl. Dis min se dɛn nɔ de mek nyu rɛd sɛl dɛn. |
| Pɛriferal Blɔd Smia | Dɛn kin tek wan drɔp blɔd ɛn chɛk am ɔnda maykroskɔp fɔ chɛk aw di rɛd blɔd sɛl dɛn shep ɛn aw dɛn tan. |
| Bone Marrow Aspirashon/Bayopsi we yu de du | Dis na di men tɛst fɔ kɔnfirm di sik . wan rili sכ mכl sεmpl fכ bon mכro dεn kin tek am frכm ples lεk di hip afta dεn anεsthεsia. pan PRCA, dεn nכ de si di stεm sεl dεm we de mek rεd bכdi sεl dεm insay. |
| Ɔda tɛst dɛn | Fɔ no wetin mek di sik, dɛn kin du tɛst lɛk Parvovirus B19 vayrɔs tɛst ɛn CT skan (fɔ chɛk fɔ lumps lɛk taymoma). |
Wetin na di tritmɛnt dɛm fɔ PRCA?
Di tritmɛnt fɔ PRCA de dipen pan wetin de mek di sik kam. Dis min se nɔto ɔlman dɛn kin gi di sem tritmɛnt. Di dɔktɔ go tek tɛm stɔdi yu sik ɛn pik di tritmɛnt we go fayn fɔ yu.
- Immunosuppressants: If di tin we de mek di sik na prɔblɛm wit di imyun sistɛm, dɛn mɛrɛsin ya de wok fɔ kɔntrol di imyun sistɛm we de wok pasmak. Dɛn kin yuz kɔtikosterɔyd lɛk Prednisone ɛn Cyclosporine fɔ dis.
- Blɔd Transfyushɔn: If di anemia rili bad, dɛn kin gi blɔd na do fɔ mek di blɔd lɛvɛl kam bak kwik kwik wan. Bɔt we pɔsin kɔntinyu fɔ transfyuz di blɔd, dat kin mek di ayrɔn we de na di bɔdi go ɔp we i nɔ nid fɔ du am. If na so i bi, dɛn go nid fɔ gɛt sɛpret tritmɛnt (chelation therapy) fɔ pul di ayɔn we pasmak.
- Ɔpreshɔn: If di tin we mek di sik na taymoma, di tritmɛnt na fɔ ɔpreshɔn fɔ pul di gland (Thymectomy).
- Immunoglobulin Therapy: If PRCA na parvovirus B19 infekshɔn, dis tritmɛnt de fɛt di vayrɔs ɛn stɔp am fɔ pwɛl di rɛd blɔd sɛl dɛn.
- Stem Sεl Transplant:Fɔ pipul dɛm wae gɛt dis sik wae dɛn bɔn lɛk Daymɔnd-Blakfan Anemia, tritmɛnt na fɔ transplant wɛl bɔdi stem sɛl dɛm fɔ tek ples fɔ bon mɛrɔ wae sik.
Ɛni bad tin de we di tritmɛnt kin du?
Yɛs, lɛk ɛni tritmɛnt, i kin gɛt bad bad tin dɛn we kin apin to am. Bɔt nid nɔ de fɔ wɔri bɔt dɛn. Yu dɔktɔ go tɛl yu bɔt ɔl dɛn tin ya bifo yu bigin fɔ trit yu. I go gi yu bak di advays we yu nid fɔ kɔntrol di bad tin dɛn we kin apin to yu.
Fɔ ɛgzampul, di mɛrɛsin dɛn we de mek yu bɔdi nɔ ebul fɔ fɛt di sik kin mek yu gɛt mɔ sik, yu blɔd prɛshɔn go ɔp, ɛn mek yu wet go ɔp. Blɔd transfyushɔn kin mek pɔsin gɛt fiva ɛn alɛji. So, i rili impɔtant fɔ pe atɛnshɔn gud wan to di chenj dɛn we de apin na yu bɔdi we yu de trit yu.
Wetin yu nid fɔ no we yu de liv wit PRCA?
Sɔntɛnde, PRCA kin bi sik we nɔ de dɔn. Dis min se ivin afta dɛn dɔn trit am, sɔntɛnde di sik kin kam bak. So, i impɔtant fɔ de ɔnda dɔktɔ in sɔpɔtishɔn.
- Mentɛnans Tɛrapi: Sɔm pipul dɛn kin nid fɔ kɔntinyu fɔ tek di mɛrɛsin dɛn we de mek dɛn nɔ gɛt bɛtɛ wɛlbɔdi fɔ mek dɛn nɔ gɛt di sik bak.
- Kɔntinyu fɔ fala: I impɔtant fɔ go to yu dɔktɔ ɔltɛm ɛn mek dɛn tɛst yu blɔd. Dis kin ɛp yu fɔ no kwik kwik wan if di sik go kam bak ɔr go gɛt ɔda prɔblɛm dɛn.
- Fɔ liv fayn layf:
- It we gɛt fayn fayn tin dɛn fɔ it: I impɔtant fɔ it tin dɛn we gɛt bɔku ayɔn (spinach, mit, pis, lentil). Aks yu dɔktɔ bɔt di it we fayn fɔ yu.
- Drink inof wata: Mek di bɔdi nɔ gɛt wata.
- Protɛkt yusɛf frɔm infɛkshɔn: Was yu an ɔltɛm. Tek tɛm na say dɛn we pipul dɛn kin bɔku. Gɛt di vaysin dɛn we yu nid.
- Ɛksesaiz: Ɛksesaiz na di lɛvul we yu bɔdi go ebul fɔ bia. Dɔn bak, go to yu dɔktɔ bɔt dis.
We yu yɛri bɔt PRCA, yu kin fil fɔ fred. Dat na nɔmal tin. Bɔt mɛmba se na sik we pɔsin kin mɛn. Di tin we impɔtant pas ɔl na fɔ go to dɔktɔ kwik kwik wan ɛn fala di tritmɛnt ɛksaktɔli, ɛn nɔ fɔ pe atɛnshɔn to di sayn dɛm.
Mɛsej we dɛn kin kɛr go na os
- PRCA na wan sik we nɔ kin apin na di blɔd we nɔ kin apin so ɔltɛm we kin mek di bon mɛro nɔ mek rɛd blɔd sɛl dɛn.
- Di men sayn dɛm wae de sho am na wae pɔrsin kin taya ɔltɛm, i kin gɛt blɛsin, ɛn i nɔ kin izi fɔ blo.
- Dis kin kam bikɔs ɔf prɔblɛm wit di imyun sistɛm, kansa, infɛkshɔn, ɛn sɔm mɛrɛsin dɛn.
- di men tεst fכ kכnfכm di sik na bon mכro bayopsi.
- Di we aw dɛn kin trit am kin difrɛn difrɛn wan bay wetin de mek pɔsin gɛt di sik, ɛn di tritmɛnt kin kɔntrol di sayn dɛm.
- Bikɔs dis kin kam bak sɔntɛnde, fɔ de wach am fɔ lɔng tɛm ɛn fɔ chɛk am ɔltɛm, rili impɔtant.
- If yu kɔntinyu fɔ gɛt sayn dɛn we tan lɛk we yu nɔ gɛt blɔd, nɔ panik ɛn go to yu dɔktɔ wantɛm wantɛm.
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