Yu dɔn yɛri bɔt Tayp 1 dayabitis? dis na di kכndyushכn we wi bכdi in כwn imyun sistεm de go haywire εn atak di sεl dεm we de prodyuz insulin na di pankrias. Dis kin mek pɔsin fred smɔl. Bɔt we di sayɛns bɔt mɛrɛsin dɔn go bifo, nyu we dɛn de kam fɔ mɛn dɛn sik ya. Wan pan dɛn nyu op dɛn de na wan mɛrɛsin we dɛn kɔl Teplizumab. Dis na wetin i de du, i de delay fɔ bigin fɔ gɛt Tayp 1 dayabitis. So lɛ wi tɔk bɔt dis tide insay wan simpul we we yu go ɔndastand.
Us kayn mɛrɛsin na Teplizumab?
Fɔ tɔk am simpul wan, Teplizumab na wan mɛrɛsin wae de alaw pipul dɛm wae de pan risk fɔ gɛt Tayp 1 dayabitis fɔ delay fɔ bigin fɔ gɛt dis sik fɔ sɔm ia. I nɔto mɛrɛsin fɔ dayabitis, bɔt i kin delay fɔ mek di sik bigin. Dat na big tin, nɔto so?
Dis drɔg de pan di grup we dɛn kɔl Monoclonal Antibody . Nɔ fred we yu yɛri da nem de. Imajin se di sojaman dɛm (antibodi dɛm) we de na wi bɔdi in imyun sistɛm de go na di rɔng rod ɛn bigin fɔ atak wi yon gud sɛl dɛm. Da tɛm de, fɔ kɔntrol dɛn sojaman ya we de mek mistek, dɛn kɔl ɔda kayn prɔtin we dɛn mek spɛshal wan na di lɛbɔraytri Monoclonal Antibody. Wetin Teplizumab de du na fɔ stɔp di imyun sistɛm in akshɔn smɔl we de mistek atak di sɛl dɛn we de mek insulin. So, di divɛlɔpmɛnt fɔ gɛt dayabitis kin delay.
Dis mɛrɛsin kin de na di makit ɔnda di brand nem Tzield .
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu bigin dis tritmɛnt
Dis rili impɔtant. Bifo yu bigin fɔ trit yu wit Teplizumab, i impɔtant fɔ tɛl yu dɔktɔ dɛn tin ya. Dɛn tin ya kin afɛkt di tritmɛnt fɔ di sakrifays ɛn yu sef dairekt wan.
| Situeshɔn we yu nid fɔ ripɔt | Wetin mek dat impɔtant? |
|---|---|
| Kɔrɛnt infɛkshɔn kɔndishɔn (e.g. fiva, kol, kɔf) . | Bikɔs dis mɛrɛsin de ridyus di wok we di imyun sistɛm de du, wan infɛkshɔn we dɔn de kin wɔs. |
| Liva sik | Bikɔs di liva impɔtant fɔ di prɔses fɔ pul drɔgs na di bɔdi, yu fɔ tɛl yu dɔktɔ if yu gɛt ɛni prɔblɛm wit di liva. |
| Di tin dɛn we de na di blɔd we dɔn go dɔŋ (rɛd blɔd sɛl dɛn, wayt blɔd sɛl dɛn, pletlɛt dɛn) . | Dis mɛrɛsin kin mek di tin dɛn we de na di blɔd go dɔŋ mɔ, so i denja if di lɛvɛl dɛn dɔn ɔlrɛdi smɔl. |
| Wan vaysin we dɛn jɔs dɔn gi ɔ we gɛt fɔ kam | Layf vayrɔs vaysin dɛn mɔ kin intarakt wit dis mɛrɛsin. So, duya gi wan kɔmplit diskripshɔn bɔt di vaysin. |
| Alɛji to ɔda mɛrɛsin, it, ɔ tin dɛn | Dis impɔtant fɔ no if yu gɛt alɛji to Teplizumab ɔ ɛni wan pan di tin dɛn we de insay am. |
| If yu de tray fɔ gɛt bɛlɛ ɔ yu gɛt bɛlɛ | Nɔr kɔmplit data stil de bɔt aw dis mɛrɛsin sef we yu gɛt bɛlɛ, so yu fɔ tɔk to yu dɔktɔ bɔt dis. |
| If yu na mama we de gi pikin in bɛlɛ | dis infכmeshכn implεnt fכ no if di mεdikeshכn de pas to di pikin tru in mama in milk. |
Aw dɛn kin gi dis mɛrɛsin to di bɔdi?
Teplizumab nɔto mɛrɛsin we yu kin kɛr go na os ɛn yuz.
- Dɛn kin gi dis as infushɔn we dɛn kin put insay di bɛlɛ (IV) .
- Dɛn kin du am na ɔspitul ɔ klinik ɔnda di sɔpɔtishɔn fɔ wan mɛdikal tim.
- Dɛn kin gi dis tritmɛnt ɛvride fɔ 14 dez.
- Bifo yu bigin fɔ trit yu, dɛn go gi yu wan spɛshal liflet (MedGuide) we gɛt di ditel dɛn bɔt dis mɛrɛsin. Rid am gud gud wan ɔltɛm.
- Dɛn kin gi dis mɛrɛsin bak to pikin dɛn we dɔn pas 8 ia ɔnda sɔm tin dɛn. Bɔt sɔm spɛshal tin dɛn de we wi fɔ no bɔt. Tɔk to yu dɔktɔ bɔt dis.
Impɔtant:If yu tink se yu dɔn tek tumɔs pan dis mɛrɛsin, kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta wantɛm wantɛm na di Kɔlɔmbɔ Nashɔnal Ospital ɔ go na di Imejɛnsi Tritmɛnt Yunit (ETU) na di ɔspitul we de nia yu.
Wetin a go du if a mis wan doz fɔ tek mɛrɛsin?
I rili impɔtant fɔ tek ɛni doz fɔ dis tritmɛnt di rayt tɛm. If yu nɔ ebul fɔ atɛnd yu tritmɛnt we dɛn dɔn sɛtul, kɔl yu wɛlbɔdi tim wantɛm wantɛm.
Tin dɛn we yu fɔ tink bɔt we yu de du tritmɛnt
Yu mɛdikal tim go tek tɛm wach yu we yu de tek dis mɛrɛsin.
- Blɔd tɛst: Yu go nid fɔ du blɔd tɛst ɔltɛm. Dɛn tin ya go chɛk di lɛvɛl we tin dɛn lɛk wayt blɔd sɛl, rɛd blɔd sɛl, ɛn di liva de wok na yu blɔd.
- Risk fɔ gɛt infɛkshɔn: Dis mɛrɛsin de ridyus di wok we di imyun sistɛm de du, we de mek yu risk fɔ gɛt infɛkshɔn. If yu gɛt sɔm sayn dɛn lɛk fiva, kol, trot we de at, ɔ kɔf, nɔr de mɛn yusɛf ɛn kɔl yu dɔktɔ wantɛm wantɛm. I fayn bak fɔ mek yu nɔ go na say dɛn we pipul dɛn sik insay dis tɛm.
- Vaysin: Dis rili impɔtant. Bitwin 6 ɛn 52 wik afta yu tek Teplizumab, yu bɔdi nɔ kin ansa di vaysin dɛn we yu kin gɛt. So if yu nid fɔ gɛt vaysin, tɛl yu dɔktɔ se yu dɔn tek Teplizumab. Yu kin nid fɔ gɛt bɔsta dos ɔ chenj yu vaksin schedule.
Sayd ɛfɛkt dɛn we kin apin bikɔs ɔf mɛrɛsin
Lɛk ɛni mɛrɛsin, Teplizumab kin mek yu gɛt sayd ɛfɛkt. Sɔm kin siriɔs, ɛn ɔda wan dɛn kin kɔmɔn.
| Sayd ɛfɛkt dɛn we dɛn fɔ ripɔt to di dɔktɔ wantɛm wantɛm | |
|---|---|
| Sayd ɛfɛkt we pɔsin kin gɛt | Tɔk bɔt |
| Alɛji Riakshɔn dɛn | Skin rash, it, swel na di fes, lip, tong ɔ trot. |
| Saytokin Rilis Sindrom (CRS) . | Dis na siriɔs tin we kin kam bikɔs di imyun sistɛm kin atak am wantɛm wantɛm. Di sayn dɛm kin bi fiva, kol, wik, ed pen, diziz, i nɔ kin izi fɔ blo, ɛn at kin bit kwik kwik wan . |
| Di sayn dɛn we de sho se pɔsin gɛt di sik | Fiva, kol, kɔf, trot we de at. |
| Sayd ɛfɛkt dɛm wae nɔr kin siriɔs (bɔt dɛn fɔ ripɔt to dɔktɔ if dɛn kɔntinyu fɔ de) . | |
| Rɔnbɛlɛ | Di bɛlɛ we de kɔmɔt na di bɛlɛ. |
| Ed de at | Ed de at. |
| Vɔmit | Fɔ fil lɛk se yu de vɔmit. |
| Skin rash we de kɔmɔt na di skin | Smɔl smɔl blista ɔ rɛdnɛs na di skin. |
Dis list nɔ de inklud ɔl di sayd ɛfɛkt dɛn we pɔsin kin gɛt. If yu gɛt ɛnitin we nɔ kɔmɔn, duya kɔntak yu dɔktɔ fɔ mek dɛn gi yu advays.
Mɛsej we dɛn kin kɛr go na os
- Teplizumab nɔto mɛrɛsin fɔ Tayp 1 dayabitis, bɔt na mɛrɛsin we kin rili delay fɔ bigin.
- Dis na spɛshal tritmɛnt we dɛn kin gi to wan vein na ɔspitul, ɔnda dɔktɔ in sɔpɔtishɔn.
- Bifo yu bigin fɔ trit yu, gi yu dɔktɔ kɔmplit diskripshɔn bɔt ɔl yu mɛrɛsin, mɛrɛsin dɛn we yu de tek, ɛn mɔ ɛni vaysin we yu dɔn gɛt.
- We dɛn de du tritmɛntTek tɛm bad bad wan pan sayn dɛm we de sho se yu gɛt di sik lɛk fiva, kɔf, ɔ Saytokine Rilis Sindrom (CRS) . If ɛni wan pan dɛn tin ya apin, tɛl yu dɔktɔ wantɛm wantɛm.
- If yu gɛt ɛni kwɛstyɔn bɔt dis mɛrɛsin, di bɛst pɔsin fɔ aks na yu dɔktɔ . Nɔ wɔri fɔ aks ɔda pipul dɛn.
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