Wetin na di sik we dɛn kɔl Wernicke-Korsakoff Syndrome? Lɛ wi tɔk bɔt am!

Yu dɔn ɛva yɛri bɔt wan strenj tin we kin afɛkt di bren ɛn mɛmori? Sɔntɛnde, wi nɔ kin ivin no se we wi bɔdi nɔ gɛt sɔm vaytamɛn dɛn, mɔ di vaytamɛn B1 we dɛn kɔl ``Thiamine``, wi bren kin pwɛl bad bad wan. Wan pan dɛn kayn siriɔs sik ya na Wernicke-Korsakoff Syndrome (WKS) . Dis na sik wae rili nid fɔ gɛt tritmɛnt kwik kwik wan. Wi go tɔk bɔt dis simpul wan, di we we yu go ɔndastand?

Wetin ɛksaktɔli na Wernicke-Korsakoff sindrom (`WKS`)?

Fɔ tɔk am simpul wan, dis na sik we de afɛkt wi bren ɛn mɛmori. di men rizin fכ dis na dat wi bכdi gεt bכku bכku dכ n pan 'Thiamine' (`Thiamine`) כ vaytam in B1 . Tink bɔt am, wi bɔdi tan lɛk motoka. Di injin fɔ dis motoka na di bren. Di injin nid petrol fɔ mek i ebul fɔ rɔn. semweso, di vaytam in we dεn kכl 'Thiamine` (`Thiamine`) implεnt fכ wi bren εn nεv sεstem fכ wok. Dis vaytamɛn na in de chenj di it we wi de it to ɛnaji. so we dis ‘Thiamine` (`Thiamine`) dכn rεdכks, di bren nכ de gεt di enεji we i nid, εn afta dat di bren sεl dεm de bigin fכ dכn.

Tu men stej de na dis `WKS`:

1. Wernicke encephalopathy: Dis na di fɔs, wantɛm wantɛm, bad bad injury na in bren. I nid fɔ gɛt tritmɛnt wantɛm wantɛm.

2. Korsakoff syndrome: Dis na wan sik wae kin teik lɔng tɛm wae kin afɛkt mɛmori bad bad wan.

Dɛn gi am in nem to wan Jamani nyurolɔjist we nem Carl Wernicke ɛn wan Rɔshian nyurolɔjist we nem Sergei Korsakoff, we bin fɔs no di sik.

Wetin na di rilayshɔn bitwin ‘Wernicke’s encephalopathy’ ɛn ‘Korsakoff syndrome’?

Dɛn tu tin ya gɛt sɔntin fɔ du wit dɛnsɛf. fכ bi prεsis, wan kכndyushכn we dεn kכl ``Wernicke encephalopathy``, if dεn nכ trit am in tεm, na in de divεlכp sכmtεm to wan siriכs mεmכri prכblεm we dεn kכl ``Korsakoff syndrome``.

Bɔrku tɛm, tri men sayn dɛm de fɔ Wernicke encephalopathy:

• Kɔnfyushɔn: Nɔ de lɔs yu kɔnshɛns, yu nɔ de gɛt ples ɛn tɛm.
• di bεlε we yu de lכs εn i nכ ebul fכ kכntrכl di muvmεnt dεm (`Ataxia`): We yu de waka nכ de stedi εn di limb dεm de at fכ kכntrכl.
• Yu kin chenj di we aw yu de si ɛn yu yay kin gɛt prɔblɛm wit yu yay: I nɔ kin muv di yay we nɔ kin muv, lɛk fɔ si tu tɛm.

Apat frɔm dis, sɔntɛnde ivin di mɔsul dɛn kin wik.

If dɛn sayn ya de fɔ lɔng tɛm, di bren ɛn di nɛv sɛl dɛn kin pwɛl fɔ ɔltɛm. Dis na wae pɔrsin kin mɛmba bad bad wan ɛn nɔr kin mɛmba nyu mɛmori. Dɛn kɔl dis ``Korsakoff syndrome``.

Wernicke-Korsakoff Syndrome (WKS) na wan sik wae kin de wɔs smɔl smɔl as tɛm de go ɛn kin ivin mek pɔrsin in layf de pan denja. So, i impɔtant fɔ trit pɔsin kwik kwik wan wit thiamine. If yu du dat, i go ɛp fɔ mek yu nɔ gɛt di sik ɛn mek yu nɔ gɛt prɔblɛm wit yu maynd ɛn ɔda tin dɛn we yu bren de du fɔ ɔltɛm.

If yu ɔ pɔsin we de nia yu gɛt dɛn sik ya, yu fɔ go to dɔktɔ wantɛm wantɛm ɔ go na ɔspitul we de nia yu.

Udat dɛn dis kayn tin kin afɛkt mɔ?

Wernicke-Korsakoff syndrome (WKS) kin bɔku pan man dɛn pas uman dɛn. I kin apin to pipul dɛm wae ol bitwin 30 ɛn 70. Bɔrku pipul dɛm wae gɛt WKS bikɔs dɛn de drink rɔm na man dɛm wae dɔn pas 40. Bɔt uman ɛn yɔŋ pipul dɛm kin gɛt dis sik bak fɔ ɔda rizin pas rɔm. Dɛn nɔ kin ripɔt am pan yɔŋ pikin dɛn.

Udat dɛn kin gɛt bɔku prɔblɛm wit di sik we dɛn kɔl Wernicke-Korsakoff syndrome?

Wernicke encephalopathy na wan sik wae dɛn kin si mɔr pan pipul dɛm wae de yuse rɔm pasmak (alcohol use disorder). We pɔsin drink rɔm fɔ lɔng tɛm, i kin pwɛl di bɛlɛ ɛn di dijestiv sistɛm. i de ambɔg bak di bכdi in ebul fכ abzכp vaytam in dεm (malabsorption). Dɛn se lɛk 80% pan di wan dɛn we de drink te dɛn chak nɔ kin ebul fɔ absɔb ɔ kip inof thiamine.

Apat frɔm dat, pipul dɛm we nɔ kin ebul fɔ absɔb it fayn fayn wan bikɔs ɔf sɔm mɛdikal kɔndishɔn dɛm kin gɛt `WKS` bak. fכ egzampl, i kin apin afta dεn du כpεrayshכn fכ lכs yu wet (`bariatric surgery`) כ as sayd ifekt fכ `kimothεrapi` fכ kεnsar.

Na sɔm ɔda tin dɛn we kin mek pɔsin gɛt prɔblɛm:

• Intestinal sik dɛm, fɔ ɛgzampul, inflammatory bowel disease ɔ gastropathy.
• Kansa (especially if i gɛt siriɔs kes dɛm).
• di tayroyd כmon lεvεl dεm we de hכy pasmak (tayrotoksikosis).
• Sɔm tin dɛn we kin chenj na di jɛnɛtiks.
• Yuz diuretic therapy fɔ at pwɛl fɔ lɔng tɛm.
• Di sik dɛn we pɔsin kin gɛt we i nɔ gɛt tiamin lɛk HIV/AIDS.
• di kidni fεil, biכs di tritmεnt fכ dayalaysis fכ lכng tεm de ridyus di bכdi in ebul fכ abzכp thiamine.
• Nɔ gɛt say fɔ mɛn pipul dɛn ɔ it we gɛt fayn fayn tin dɛn fɔ it.
• Vכmit pasmak εn nכs we yu bεlε (hyperemesis gravidarum).

Wetin na di tin dɛm wae kin mek pɔrsin gɛt ‘Wernicke-Korsakoff syndrome’?

di men rizin fכ dis na di dεfisit fכ ``Thiamine``. Dis impɔtant vaytamɛn na in de chenj di shuga we wi de it to ɛnaji. so we wi nכ gεt inof ``Thiamine``, wi bren nכ de gεt di enεji we i nid fכ wok fayn fayn wan.

Di men tin we kin mek pɔsin nɔ gɛt thiamine naFɔ drink pasmak fɔ lɔng tɛm. Alkol kin mek i nɔ izi fɔ di bɔdi fɔ tek thiamine ɛn kip am na di liva. Alkol de ambɔg bak di yus fɔ vaytamɛn B1 fɔ ɔda impɔtant wok dɛn.

Ɔda rizin dɛn de bak:

• Nɔ it fayn: Nɔ it tin we balans.
• Disɔda wae de kam wit aw pɔrsin de it: lɛk anorexia ɛn bulimia.
• Infɛkshɔn dɛn we nɔ de mɛn.
• Ɔpreshɔn: Ɛspɛshali ɔpreshɔn lɛk gastric bypass ɔpreshɔn fɔ mek yu nɔ gɛt bɔku bɔku bɔdi.
• Traumatik bren injuri: Bɔt dis nɔ kin apin smɔl.

Wetin na di sayn dɛm fɔ ‘Wernicke-Korsakoff syndrome’?

Dis kin sho pan difrɛn kayn sayn dɛm. Wan pan di kɔmɔn sayn dɛm we dɛn kin si pan siriɔs kes na ‘kɔnfabuleshɔn’ . Dat min se fɔ mek stori dɛn na yu maynd fɔ kɔba tin dɛn we yu nɔ mɛmba. Imajin, pɔsin nɔ mɛmba sɔntin we dɛn du yestede, bɔt dɛn kin lay fɔ kɔba am, bɔt dɛn nɔ de lay bikɔs dɛn tink se i rili apin. Dɛn biliv di stori.

Bɔrku tɛm, pipul dɛm wae gɛt dis sik kin fil fɔ kɔnfyus ɔr nɔr de fil fayn. Dis kɔnfyushɔn kin mek i nɔ izi fɔ dɛn fɔ no se sɔntin nɔ de apin to dɛn ɛn fɔ go to tritmɛnt.

Di kɔmɔn simptom dɛm fɔ Wernicke encephalopathy:

• di bεlε we i de lכs כ we i nכ ebul fכ kכntrכl di muvmεnt dεm (ataxia).
• 'Kɔnfabuleshɔn'.
• Kɔnfyushɔn, delirium.
• I nɔ izi fɔ waka, yu nɔ de waka fayn.
• Di we aw pɔsin kin slip.
• di tεmprachכ na di bכdi we nכ nכmal (haypothermia).
• At prɔblɛm: at rit we de go ɔp (tachycardia) ɔ blɔd prɛshɔn we de dɔŋ (haypotension).
• di kכdכnayshכn na di mכsul dεm we de lכs (ataxia).

Prɔblɛm dɛn we kin apin na di yay kin bɔku bak:

• Abnɔmal ay muvmɛnt (nystagmus).
• Dabl vishɔn.
• Di ɔpa aylid we de drɔp (ptosis).
• di ay mכsul dεm nכ de wok fayn כ i wik (ophthalmoplegia).

If dɛn nɔ trit di Wernicke encephalopathy, i kin go to Korsakoff syndrome, we na wan prɔblɛm we kin mek pɔsin mɛmba fɔ lɔng tɛm. Di sayn dɛm we i kin gɛt na:

• Kכmplit lכs fכ mεmכri (`Amnesia`) כ we yu nכ ebul fכ mεmba εni nyu tin.
• Di chenj dɛn we de apin na di we aw pɔsin de biev: i kin vɛks, i kin vɛks kwik.
• 'Kɔnfabuleshɔn'.
• Delirium ɛn disoriɛnteshɔn.
• Taya ɔ taya.
• Hallucinations, mɔ we yu de lɛf fɔ drink rɔm.
• Nɔ ebul fɔ pe atɛnshɔn pan sɔntin.
• We yu nɔ de waka fayn.

Sɔm sayn dɛm nɔ kin bɛtɛ ɔltogɛda ivin if dɛn trit am. If yu gɛt siriɔs kes, yu kin lɔs yu kɔnshɛns (`koma`). If yu ɔ pɔrsin wae de nia yu nɔr no natin, ɔr if yu gɛt sayn dɛm fɔ `Wernicke-Korsakoff syndrome`, go to dɔktɔ ɔr go na imejensi rum kwik kwik wan.

Aw dɛn kin no se pɔsin gɛt ‘Wernicke-Korsakoff syndrome’?

fכ no dis `WKS` kכndishכn kwik kwik wan na implεnt fכ saksesful tritmεnt. Dɔktɔ dɛn kin no if yu gɛt am bay we dɛn de du ɛgzam pan yu bɔdi, aks bɔt di sayn dɛn we yu gɛt, ɛn aks bɔt yu famili istri. Bɔt i nɔ kin izi fɔ no if pɔsin kɔnfyus ɔ we i nɔ ebul fɔ mɛmba.

Di dɔktɔ go chɛk fɔ dɛn tin ya spɛshal wan:

• Ɛni prɔblɛm de fɔ yuse rɔm (`Alcohol use disorder`)?
• Yu tink se pipul dɛn nɔ de it fayn?
• Yu tink se thiamine deficiency de?

Us tɛst dɛn kin ɛp fɔ no if pɔsin gɛt di sik we dɛn kɔl Wernicke-Korsakoff syndrome?

Yu dɔktɔ go ɔda fɔ mek dɛn du blɔd tɛst fɔ chɛk yu blɔd shuga ɛn thiamine lɛvɛl. Dɛn kin ɔda bak fɔ mek dɛn du blɔd alkol tɛst fɔ chɛk if yu de drink rɔm ɛn fɔ mek dɛn liva wok fɔ chɛk di liva we de wok, bikɔs dis kin sho se di liva dɔn pwɛl.

Dɛn kin du ɔda tɛst fɔ chɛk fɔ ɔda tin dɛn we kin mek dɛn du am:

• Arterial blood gas (ABG) test, we de chɛk di lɛvɛl we di kabon dayɔgzayd ɛn ɔksijɛn de na di blɔd.
• 'Kɔmplit blɔd kɔnt' (`Kɔmplit blɔd kɔnt - CBC`).
• Toksikɔlɔji skrinin.

Yu kin nid bak fɔ gɛt imej tɛst dɛn lɛk dɛn wan ya:

• 'CT skan' we dɛn kɔl.
• 'MRI' (`MRI`) we dɛn kɔl.
• 'Ilektrokardiogram' (`Ilektrokardiogram - EKG`).

Yu tink se dɛn kin mɛn di sik we dɛn kɔl Wernicke-Korsakoff Syndrome? Aw dɛn kin trit am?

Infakt, i nɔ kin wɛl ɔl. Bɔt if dɛn bigin fɔ trit am kwik, di sayn dɛn kin kɔmɔt ɛn sɔm pan dɛn kin chenj. dis min se dεn kin stכp di kכndyushכn ``Wernicke encephalopathy`` fכ wכs to ``Korsakoff syndrome``.

Bɔrku tɛm, tritmɛnt kin kɔntrol ɔr kin ɛp fɔ mek pɔrsin fil fayn lɛk fɔ kɔnfyus, fɔ gɛt prɔblɛm wit yu yay, ɛn fɔ lɛ yu nɔr gɛt bɛtɛ balans. Yu dɔktɔ go mek wan tritmɛnt plan we go fayn fɔ yu.

Dɛn kin du dɛn tin ya as tritmɛnt:

• Gi vaytamɛn B1 tru pils ɔ injɛkshɔn.
• If di bɔdi nɔ gɛt wata, gi salin tru ``IV fluid``.
• Fɔ trit prɔblɛm dɛn we gɛt fɔ du wit fɔ drink rɔm.
• Fɔ gi sɔpɔt we gɛt fɔ du wit nyutrishɔn.
• Gi ɔda mɛrɛsin dɛn if nid de.

Aw yu go ridyus de risk fɔ gɛt dis sik?

Bɔrku tɛm, fɔ stɔp ɔr nɔr de drink pasmak na di impɔtant tin wae yu kin du fɔ ridyus yu risk fɔ gɛt Wernicke-Korsakoff syndrome. Dɔn bak, fɔ gɛt gud it ɛn if nid de, fɔ tek thiamine sɔpɔtmɛnt dɛn we tan lɛk injɛkshɔn ɔ pils kin ɛp fɔ ridyus yu risk, mɔ fɔ di wan dɛn we gɛt adikshɔn to rɔm.

Wetin na di prɔgnosis fɔ pɔrsin wae gɛt Wernicke-Korsakoff syndrome?

If yu ɔr pɔrsin wae de nia yu gɛt dis sik, de prɔgnosis de dipen pan aw de sik kin tranga ɛn aw kwik fɔ no ɛn trit de sik. If yu trit yu kwik kwik wan, i kin rivεs di sayn dεm εn i kin mek i nɔr gɛt prɔblɛm dɛn we go de fɔ lɔng tɛm. Bɔt if dɛn nɔ trit am, i kin mek i nɔ ebul fɔ waka ɛn i kin ivin day.

Ustɛm yu fɔ go to dɔktɔ fɔ dis sik?

If yu ɔ pɔrsin wae yu sabi gɛt sɔm kayn sik wae de mɛk yu gɛt dis sik, go to dɔktɔ kwik kwik wan. Yu kin nid fɔ kɔl yu dɔktɔ ɔ go na di ɔspitul imejensi rum we de nia yu fɔ gɛt imejensi tritmɛnt.

Aw a kin kia fɔ misɛf?

Fɔ gɛt diagnosis fɔ Wernicke-Korsakoff syndrome nɔto izi wok. Yu kin nid fɔ go na ɔspitul ɛn gɛt tritmɛnt. Di tin we impɔtant pas ɔl na fɔ fala yu dɔktɔ in advays, lɛk fɔ stɔp fɔ drink rɔm (ɔ fɔ kɔt am kɔmɔt kpatakpata) ɛn fɔ it tin dɛn we gɛt fayn fayn tin dɛn fɔ du. Dɛn tin ya go rili sɔpɔt yu fɔ wɛl.

Fɔ fala yu dɔktɔ in instrɔkshɔn dɛn fayn fayn wan fɔ manej di prɔblɛm dɛn ɛn trit di sayn dɛm. I go mek wan pɔrsin in yon kia plan we go fayn fɔ yu ɛn ɛp yu fɔ gɛt yu wɛlbɔdi bak.

Wernicke-Korsakoff syndrome na wan sik wae nɔr kin bɔrku bɔt wae kin siriɔs fɔ mɛmba. I nid fɔ gɛt tritmɛnt kwik kwik wan fɔ mek i nɔ gɛt di sik ɛn fɔ mek i nɔ gɛt prɔblɛm dɛn. As di sik de go bifo, sɔm sayn dɛm fɔ di nervɔs sistɛm, lɛk fɔ kɔnfyus bad bad wan ɛn fɔ nɔr de no wetin fɔ du, kin apin. Dɛn sayn ya kin mek i nɔr izi fɔ yu ɔr pɔrsin wae de nia yu fɔ no yu sik. So, i impɔtant fɔ no di sik kwik kwik wan. Yu dɔktɔ go tɛl yu fɔ gi yu tritmɛnt plan we go mek yu nid am.

Di tin dɛn we impɔtant pas ɔl fɔ mɛmba (Take-Home Message) .

Okay, so na di men tin dɛm fɔ mɛmba bɔt di `Wernicke-Korsakoff Syndrome` we wi bin tɔk bɔt:

• dis na siriכs kכndyushכn we de afekt di bren εn mεmכri biכs fכ di dεfisit fכ thiamine (vitamin B1).
• Di men tin we kin mek pɔsin gɛt dis sik na fɔ drink pasmak.
• Di fɔs stej na Wernicke encephalopathy, we if dɛn nɔ trit am, i kin mek yu gɛt prɔblɛm wit mɛmori fɔ lɔng tɛm we dɛn kɔl Korsakoff syndrome.
• Kɔnfyushɔn, i nɔ kin izi fɔ waka, i nɔ kin si fayn, ɛn i nɔ kin mɛmba bɛtɛ tin kin bi di men sayn dɛm.
• Fɔ no di sik kwik kwik wan ɛn fɔ trit am kwik kwik wan wit thiamine impɔtant.
• Pan ɔl we i nɔ go ebul fɔ wɛl ɔl, tritmɛnt kwik kwik wan kin kɔntrol di sayn dɛn ɛn mek i nɔ pwɛl sote go.
• If yu ɔ pɔsin we yu sabi de sho dɛn kayn sik ya, go to dɔktɔ wantɛm wantɛm.

A op se dis infɔmeshɔn go yusful to yu. Stay wit wɛlbɔdi!

` Wernicke-Korsakoff syndrome, thiamine deficiency, vaytamɛn B1, yus rɔm, mɛmori pwɛl, bren dizayd, nyurolɔjik sik